OOIR: Observatory of International Research

Papers

(The H4-Index of Medicinal Chemistry Research is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Synthesis, characterization and in vitro antitumor activity of asiatic acid derivatives	109
Potent α-glucosidase inhibitory activity of inoscavin A from fruiting bodies of Fulvifomes fastuosus: Mechanism of action, molecular docking and ADMET	96
Targeting cAMP signaling and phosphodiesterase 4 for liver disease treatment	81
Computer-aided design, synthesis and evaluation of new SARS-CoV-2 Mpro inhibitors based on 1,5,6,7-tetrahydro-4H-indazol-4-one scaffold	78
Design, synthesis, and antitumor activity evaluation of carbazole derivatives with potent HDAC inhibitory activity	67
Carbamoyl flavonoids as dual inhibitors of acetylcholinesterase and monoacylglycerol lipase: synthesis, in vitro evaluation, and computational studies	62
Novel imino-thiazoloquinoxaline derivatives against renal cell carcinoma: less radiation-damaging approach	55
Evaluation of a series of nucleoside analogs as effective anticoronaviral-2 drugs against the Omicron-B.1.1.529/BA.2 subvariant: A repurposing research study	55
Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal m	54
Antibacterial, antifungal activities and toxicity of new synthetic fatty acid salicylate esters	52
Synthesis of the dibenzylbutane lignan LCA derivatives and evaluation of their anti-inflammatory activities	46
Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic antic	44
Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent	44
Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids	42
Anticancer activity of amide and ester derivatives of the ent-labdane 2α-hydroxyeperuic acid obtained via sonochemical synthesis	40
Monoamine oxidase inhibition by thiazole derivatives substituted with the benzenesulfonamide moiety	39
Glutathione and glutathione disulfide – their biomedical and pharmaceutical applications	39
Synthesis of berberine derivatives and their antiviral activity toward respiratory syncytial virus	36
Asciminib: first FDA approved allosteric inhibitor of BCR-ABL1 for the treatment of chronic myeloid leukemia	36
Synthesis of tetrahydro-β-carboline analogs with N11 modifications and study of their antimalarial activities	35
Screening of small molecule compounds targeting hnRNPA2 protein	34
Design and synthesis of diphenyl-1H-imidazole analogs targeting Mpro/3CLpro enzyme of SARS-CoV-2	33
Contrasting effect of different crowding agents on pseudoknot RNA stability	31
Plant-derived pyroptosis inducers as a therapeutic strategy in drug-resistant cancers	30
A versatile strategy for the synthesis of various lumazine peptides	29

Evaluation of benzoylacetonitriles as novel anti-neuroinflammatory agents