Molecular Biology of the Cell

Article	Citations
Role of 2-hydroxy acyl-CoA lyase HACL2 in odd-chain fatty acid production via α-oxidation in vivo	106
A role for Nup153 in nuclear assembly reveals differential requirements for targeting of nuclear envelope constituents	75
The Toxoplasma gondii homolog of ATPase inhibitory factor 1 is critical for mitochondrial cristae maintenance and stress response	55
Optogenetic control of receptor-mediated growth cone dynamics in neurons	53
Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2	41
TUDCA modulates drug bioavailability to regulate resistance to acute ER stress in Saccharomyces cerevisiae	41
Valosin-containing protein p97 extracts capping protein CP110 from the mother centriole to promote ciliogenesis	40
Roles for the canonical polarity machinery in the de novo establishment of polarity in budding yeast spores	38
When everything is a master regulator, nothing is	36
Preprint Highlight: Distinct regions of Helicobacter pylori's bactofilin CcmA regulate protein-protein interactions to control helical cell shape	35
Preprint Highlight: Mitotic clustering of pulverized chromosomes from micronuclei	34
In vivo imaging reveals independent intraflagellar transport of the nexin–dynein regulatory complex subunits DRC2 and DRC4	33
Yeast Nst1 is a novel component of P-bodies and is a specific suppressor of proteasome base assembly defects	32
Tracheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating	32
Inclusion: an individual pursuit requiring organization-level investment to sustain it	32
The Arp2/3 complex enhances cell migration on elastic substrates	32
Laser ablation reveals the impact of Cdc15p on the stiffness of the contractile ring	31
Evaluation of cell segmentation methods without reference segmentations	31
Dynamics of intracellular neonatal Fc receptor–ligand interactions in primary macrophages using biophysical fluorescence techniques	30
2021 ASCB Annual Meeting abstracts	29
Bistability in the polarity circuit of yeast	28
A WICB 50th Favorite: Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment	27
Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration	27
Results from the MBoC Preprint Highlight experiment	26
Inner-nuclear-membrane–associated degradation employs Dfm1-independent retrotranslocation and alleviates misfolded transmembrane-protein toxicity	25

ALK1 regulates the internalization of endoglin and the type III TGF-β receptor	25
Synaptobrevin-2 dependent regulation of single synaptic vesicle endocytosis	24
CANVS: an easy-to-use application for the analysis and visualization of mass spectrometry–based protein–protein interaction/association data	24
Centromere proteins are asymmetrically distributed between newly divided germline stem and daughter cells and maintain a balanced niche in Drosophila males	23
Science: priceless, but costly	23
Modulating RhoA effectors induces transitions to oscillatory and more wavelike RhoA dynamics in Caenorhabditis elegans zygotes	23
2020 in 20/20 hindsight	23
A fine balance among key biophysical factors is required for recovery of bipolar mitotic spindle from monopolar and multipolar abnormalities	22
p52Shc regulates the sustainability of ERK activation in a RAF-independent manner	22
E2F4’s cytoplasmic role in multiciliogenesis is mediated via an N-terminal domain that binds two components of the centriole replication machinery, Deup1 and SAS6	22
Calcineurin promotes adaptation to chronic stress through two distinct mechanisms	22
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic	22
Preprint Highlight: Multiplexed bioluminescence microscopy via phasor analysis	21
Preprint Highlight: Shelterin components modulate nucleic acids condensation and phase separation in the context of telomeric DNA	21
Dimerization activates the Inversin complex in C. elegans	21
Preprint Highlight: PGC1α regulates the endothelial response to fluid shear stress via telomerase reverse transcriptase control of heme oxygenase‐1	21
The cell-end protein Tea4 spatially regulates hyphal branch initiation and appressorium remodeling in the blast fungus Magnaporthe oryzae	21
Preprint Highlight: All-optical visualization of specific molecules in the ultrastructural context of brain tissue	21
A novel tool for the unbiased characterization of epithelial monolayer development in culture	21
The outer kinetochore components KNL-1 and Ndc80 complex regulate axon and neuronal cell body positioning in the C. elegans nervous system	20
Preprint Highlight: Disentangling cadherin-mediated cell-cell interactions in collective cancer cell migration	20
Preprint Highlight: Hyphal compartmentalization and sporulation in Streptomyces require the conserved cell division protein SepX	20
SET levels contribute to cohesion fatigue	19
Recruitment of PI4KIIIβ to the Golgi by ACBD3 is dependent on an upstream pathway of a SNARE complex and golgins	19
STMND1 is a phylogenetically ancient stathmin which localizes to motile cilia and exhibits nuclear translocation that is inhibited when soluble tubulin concentration increases	19
Preprint Highlight: Lateral and longitudinal compaction of PRC1 overlap zones drives stabilization of interzonal microtubules	19
Preprint Highlight: A lysosomal lipid transport pathway that enables cell survival under choline limitation	18
The ring saga: looking back at the discovery of γ-tubulin and γ-tubulin ring complexes	18
Preprint Highlight: LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia via Transcription Factor E3 Inhibition	18
You are the most valuable reagent in the lab: mental health before and during the pandemic	17
The roles of yeast formins and their regulators Bud6 and Bil2 in the pheromone response	17
The p24-family and COPII subunit SEC24C facilitate the clearance of alpha1-antitrypsin Z from the endoplasmic reticulum to lysosomes	17
Preprint Highlight: Dodecaploid Xenopus longipes provides insight into the emergence of size scaling relationships during development	17
Load adaptation by endocytic actin networks	17
Whi5 is diluted and protein synthesis does not dramatically increase in pre-Start G1	17
Disruption of a ∼23–24 nucleotide small RNA pathway elevates DNA damage responses inTetrahymena thermophila	17
p97/VCP Promotes the Recycling of Endocytic Cargo	17
A model of actin-driven endocytosis explains differences of endocytic motility in budding and fission yeast	16
We need to address ableism in science	16
ER-localized phosphatidylethanolamine synthase plays a conserved role in lipid droplet formation	16
Spatial variation of microtubule depolymerization in large asters	16
Cell adaptation to aneuploidy by the environmental stress response dampens induction of the cytosolic unfolded-protein response	16
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to intraflagellar transport turnaround involving ICK/CILK1	16
Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1	16
The N-terminal tail of C. elegans CENP-A interacts with KNL-2 and is essential for centromeric chromatin assembly	16
Cdc7-mediated phosphorylation of Cse4 regulates high-fidelity chromosome segregation in budding yeast	16
Sequestration of the exocytic SNARE Psy1 into multiprotein nodes reinforces polarized morphogenesis in fission yeast	15
Improved tools for live imaging of F-actin structures in yeast	15
Landmarks in the discovery of a role for actin in cell locomotion	15
BORC-ARL8-HOPS ensemble is required for lysosomal cholesterol egress through NPC2	15

Trisomy 21 increases microtubules and disrupts centriolar satellite localization	15
Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience	15
Coordinated efforts of different actin filament populations are needed for optimal cell wound repair	15
After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells	15
Superresolution light microscopy of the Drosophila histone locus body reveals a core–shell organization associated with expression of replication–dependent histone genes	15
Interface extension is a continuum property suggesting a linkage between AP contractile and DV lengthening processes	15
Tip60 acetylation of histone H3K4 temporally controls chromosome passenger complex localization	15
Identification of defined structural elements within TOR2 kinase required for TOR complex 2 assembly and function in Saccharomyces cerevisiae	15
Evidence for low-level translation in human erythrocytes	15
Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence	15
The biochemical composition of the actomyosin network sets the magnitude of cellular traction forces	15
Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei	14
The ciliary lumen accommodates passive diffusion and vesicle-assisted trafficking in cytoplasm–ciliary transport	14
K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15	14
Centrosomal enrichment and proteasomal degradation of SYS-1/β-catenin requires the microtubule motor dynein	14
L-bodies are RNA–protein condensates driving RNA localization in Xenopus oocytes	14
Sec18 binds the tethering/SM complex HOPS to engage the Qc-SNARE for membrane fusion	14
An invariant C-terminal tryptophan in McdB mediates its interaction and positioning function with carboxysomes	14
Modeling a disease-correlated tubulin mutation in budding yeast reveals insight into MAP-mediated dynein function	14
Image-based discrimination of the early stages of mesenchymal stem cell differentiation	14
Mutation of the PEBP-like domain of the mitoribosomal MrpL35/mL38 protein results in production of nascent chains with impaired capacity to assemble into OXPHOS complexes	14
Regulation of neurofilament length and transport by a dynamic cycle of phospho-dependent polymer severing and annealing	13
Identification of a Golgi-localized peptide reveals a minimal Golgi-targeting motif	13
How many authors does it take to publish a high profile or classic paper?	13
The tubulin structure, a quarter of a century later	13
Endosomal actin branching, fission, and receptor recycling require FCHSD2 recruitment by MICAL-L1	13
A conundrum in 3-D genome organization and expression?	13
The ASCB andMBoC: Our cell biology power couple	13
The mitochondrial RNA granule modulates manganese-dependent cell toxicity	13
On the role of myosin-induced actin depolymerization during cell migration	13
Actin contraction controls nuclear blebbing and rupture independent of actin confinement	13
SARS-CoV-2 down-regulates ACE2 through lysosomal degradation	13
Cardiac inducing colonies halt fibroblast activation and induce cardiac/endothelial cells to move and expand via paracrine signaling	13
An approach for quantitative mapping of synaptic periactive zone architecture and organization	13
Plasma membrane protrusions mediate host cell–cell fusion induced by Burkholderia thailandensis	12
Newfound features of meiotic chromosome organization that promote efficient congression and segregation in Caenorhabditis elegans oocytes	12
α–Catenin-dependent vinculin recruitment to adherens junctions is antagonistic to focal adhesions	12
BioID2 screening identifies KIAA1671 as an EPS8 proximal factor that marks sites of microvillus growth	12
From pixels to phenotypes: Integrating image-based profiling with cell health data as BioMorph features improves interpretability	12
Systematic analysis of microtubule plus-end networks defines EB-cargo complexes critical for mitosis in budding yeast	12
Suppression of chromosome instability by targeting a DNA helicase in budding yeast	12
Differential nuclear import regulates nuclear RNA inheritance following mitosis	12
Scaling of nuclear numbers and their spatial arrangement in skeletal muscle cell size regulation	12
Lithium-induced ciliary lengthening sparks Arp2/3 complex–dependent endocytosis	12
F-actin–rich territories coordinate apoptosome assembly and caspase activation during DNA damage–induced intrinsic apoptosis	12
A defined tubby domain β-barrel surface region of TULP3 mediates ciliary trafficking of diverse cargoes	11
Deciphering the roles of cell shape and Fat and Dachsous planar polarity in arranging the Drosophila apical microtubule network through quantitative image analysis	11
The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells	11
Violin SuperPlots: visualizing replicate heterogeneity in large data sets	11
CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis	11
Breast cancer cells promote osteoclast differentiation in an MRTF-dependent paracrine manner	11
Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E	11
Activation of CWI pathway through high hydrostatic pressure, enhancing glycerol efflux via the aquaglyceroporin Fps1 in Saccharomyces cerevisiae	11
Branched microtubule nucleation and dynein transport organize RanGTP asters in Xenopus laevis egg extract	11
Fluorescence complementation-based FRET imaging reveals centromere assembly dynamics	11
Survey of cancer cell anatomy in nonadhesive confinement reveals a role for filamin-A and fascin-1 in leader bleb–based migration	11
CDK signaling via nonconventional CDK phosphorylation sites	11
Mannose receptor (MRC1) mediates uptake of dextran by bone marrow–derived macrophages	11
Loss of the HOPS complex disrupts early-to-late endosome transition, impairs endosomal recycling and induces accumulation of amphisomes	10
TFG regulates inner COPII coat recruitment to facilitate anterograde secretory protein transport	10
Cytoplasmic redox imbalance in the thioredoxin system activates Hsf1 and results in hyperaccumulation of the sequestrase Hsp42 with misfolded proteins	10
Docosahexanoic acid signals through the Nrf2–Nqo1 pathway to maintain redox balance and promote neurite outgrowth	10
Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch	10
Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis	10
Divergent regulation of α-arrestin ARRDC3 function by ubiquitination	10
Calcium-binding Cab45 regulates the polarized apical secretion of soluble proteins in epithelial cells	10
Mitotic spindle membranes	10
PI(3)P and DFCP1 regulate the biogenesis of lipid droplets	10
Polymer models reveal how chromatin modification can modulate force at the kinetochore	10
Occludin and tricellulin facilitate formation of anastomosing tight-junction strand network to improve barrier function	10
DNA damage–induced EMT controlled by the PARP-dependent chromatin remodeler ALC1 promotes DNA repair efficiency through RAD51 in tumor cells	10
Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity	10
Nucleoli and the nucleoli–centromere association are dynamic during normal development and in cancer	10
Nanotopography modulates cytoskeletal organization and dynamics during T cell activation	10
Preprint Highlight: Contractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis	10
Polysome profiling is an extensible tool for the analysis of bulk protein synthesis, ribosome biogenesis, and the specific steps in translation	10
Cross talk-dependent cortical patterning of Rho GTPases during cell repair	10
Depicting a cellular space occupied by condensates	10
Plakophilin 3 and Par3 facilitate desmosomes’ association with the apical junctional complex	10
In pancreatic β-cells myosin 1b regulates glucose-stimulated insulin secretion by modulating an early step in insulin granule trafficking from the Golgi	10

Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia	10
Calcium dynamics of skin-resident macrophages during homeostasis and tissue injury	10
Proteomic analysis of microtubule inner proteins (MIPs) in Rib72 null Tetrahymena cells reveals functional MIPs	10
The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activity	10
Zooming in on the cell biology of disease	9
Modeling and analysis of the macronutrient signaling network in budding yeast	9
Baculovirus actin-rearrangement-inducing factor ARIF-1 induces the formation of dynamic invadosome clusters	9
Mechanobiology: forcing the second act	9
Scaling of stochastic growth and division dynamics: A comparative study of individual rod-shaped cells in the Mother Machine and SChemostat platforms	9
The story of science: successes, failures, luck, privilege, and bias	9
Quantitative biophysical metrics for rapid evaluation of ovarian cancer metastatic potential	9
Negative-sense RNA viruses: An underexplored platform for examining virus–host lipid interactions	9
Preprint Highlight: Transcriptomic changes highly similar to Alzheimer's disease are observed in a subpopulation of individuals during normal brain aging	9
Calcium flow at ER-TGN contact sites facilitates secretory cargo export	9
LIN-10 can promote LET-23 EGFR signaling and trafficking independently of LIN-2 and LIN-7	9
Evolutionary divergence of anaphase spindle mechanics in nematode embryos constrained by antagonistic pulling and viscous forces	9
Quantitative visualization of endocytic trafficking through photoactivation of fluorescent proteins	9
Heterologous expression of Dictyostelium discoideum NE81 in mouse embryo fibroblasts reveals conserved mechanoprotective roles of lamins	9
ZC3HC1 is a structural element of the nuclear basket effecting interlinkage of TPR polypeptides	9
Tepsin binds LC3B to promote ATG9A trafficking and delivery	9
Preprint Highlight: Vimentin intermediate filaments organize organellar ER architecture in response to stress	8
Preprint Highlight: A motor-based approach to induce chromosome-specific mis-segregations in human cells	8
Preprint Highlight: Polarized Disheveled dissolution and condensation drives embryonic axis specification in oocytes	8
Career advice from my father: “Go where you are loved”	8
Preprint Highlight: Actomyosin cables position cell cohorts during Drosophila germband retraction by entraining their morphodynamic and mechanical properties	8
Salmonella-induced cholesterol accumulation in infected macrophages suppresses autophagy via mTORC1 activation	8
Preprint Highlight: ERK-mediated curvature feedback regulates branching morphogenesis in lung epithelial tissue	8
Preprint Highlight: ATR protects centromere identity by promoting DAXX association with PML nuclear bodies	8
Preprint Highlight: Self‐supervised deep learning encodes high-resolution features of protein subcellular localization	8
Preprint Highlight: Dynamic interplay of protrusive microtubule and contractile actomyosin forces drive tissue extension	8
Preprint Highlight: Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding	8
The ER protein Ema19 facilitates the degradation of nonimported mitochondrial precursor proteins	8
Cell type- and transcription-independent spatial proximity between enhancers and promoters	8
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation	8
Preprint Highlight: Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer	8
Preprint Highlight: A synthetic signaling network imitating the action of immune cells in response to bacterial metabolism	8
EHD2 regulates plasma membrane integrity and downstream insulin receptor signaling events	8
Preprint Highlight: Collagen remodeling dictates pancreatic cancer bioenergetics and outcome through DDR1 activation or degradation	8
Nascent adhesions shorten the period of lamellipodium protrusion through the Brownian ratchet mechanism	8
CARMIL1-AA selectively inhibits macropinocytosis while sparing autophagy	8
Solo regulates the localization and activity of PDZ-RhoGEF for actin cytoskeletal remodeling in response to substrate stiffness	8
Preprint Highlight: Detyrosination enrichment on microtubule subsets is established by the interplay between a stochastically acting enzyme and microtubule stability	8
The nuclear isoforms of the Fragile X mental retardation RNA-binding protein associate with genomic DNA bridges	7
Preprint Highlight: Pressure and curvature control of contact inhibition in epithelia growing under spherical confinement	7
Agent-based modeling predicts RAC1 is critical for ovarian cancer metastasis	7
TSC2-mTORC1 axis regulates morphogenesis and neurological function of Gli1+ adult-born dentate granule cells	7
Correction	7
Cortical dynein drives centrosome clustering in cells with centrosome amplification	7
Nonmuscle myosin IIB is a driver of cellular reprogramming	7
Paradigms Lost Perspectives: revisiting well-worn models and concepts	7
Regulation ofBlos1by IRE1 prevents the accumulation of Huntingtin protein aggregates	7
Direct observation of the conformational states of formin mDia1 at actin filament barbed ends and along the filament	7
A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly	7
Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins	7
Superresolution microscopy reveals actomyosin dynamics in medioapical arrays	7
Fast and parallel nanoscale three-dimensional tracking of heterogeneous mammalian chromatin dynamics	7
Quantitative live-cell PALM reveals nanoscopic Faa4 redistributions and dynamics on lipid droplets during metabolic transitions of yeast	7
Resolving the two-body problem: A postulated role for the V0 sector of the V0V1-ATPase in exosome biogenesis and multivesicular body fate	7
Katnip is needed to maintain microtubule function and lysosomal delivery to autophagosomes and phagosomes	7
High extracellular glucose promotes cell motility by modulating cell deformability and contractility via the cAMP-RhoA-ROCK axis in human breast cancer cells	7
A practical guide to expert learner skills in the research environment	7
VAMP5 promotes Fcγ receptor-mediated phagocytosis and regulates phagosome maturation in macrophages	7
TTBK2 controls cilium stability by regulating distinct modules of centrosomal proteins	7
Noncanonical Wnt/Ror2 signaling regulates cell–matrix adhesion to prompt directional tumor cell invasion in breast cancer	7
DAmFRET measures saturating concentrations and toxicities of protein phase transitions in vivo	7
The kinesin Kar3 is required for endoplasmic reticulum–associated degradation	7
Extracellular matrix regulates force transduction at VE-cadherin junctions	7
Performance of deep learning restoration methods for the extraction of particle dynamics in noisy microscopy image sequences	7
Basal body organization and cell geometry during the cell cycle in Tetrahymena thermophila	7
2024 ASCB Annual Meeting Abstracts	7
Membrane fusion by Drosophila atlastin does not require GTP hydrolysis	7
Mechanosensitive mTORC2 independently coordinates leading and trailing edge polarity programs during neutrophil migration	7
Dendritic effects of genetically encoded actin-labeling probes in cultured hippocampal neurons	7
A modified motor-clutch model reveals that neuronal growth cones respond faster to soft substrates	7
Evidence for a nuclear role for Drosophila Dlg as a regulator of the NURF complex	7
Insights into the role of Nup62 and Nup93 in assembling cytoplasmic ring and central transport channel of the nuclear pore complex	7
Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids	7
Measurement of solubility product reveals the interplay of oligomerization and self-association for defining condensate formation	6
Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane	6
The Role of Nde1 phosphorylation in interkinetic nuclear migration and neural migration during cortical development	6
HSPA8 inhibitors augment cancer chemotherapeutic effectiveness via potentiating necroptosis	6
New signaling kid on the block: the role of the postmitotic midbody in polarity, stemness, and proliferation	6
A methodology for specific disruption of microtubule polymerization into dendritic spines	6
Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone	6
A mathematical model of calcium signals around laser-induced epithelial wounds	6
Maximizing Access to Cell Biology for PEERS: Retracting the term minority in favor of a more inclusive lexicon	6
Endoplasmic Reticulum Exit Sites scale with somato-dendritic size in neurons	6
Sodium arsenite induces aggresome formation by promoting PICK1 BAR domain homodimer formation	6
Myosin light chain kinase-driven myosin II turnover regulates actin cortex contractility during mitosis	6
γ-tubulin complex controls the nucleation of tubulin-based structures in Apicomplexa	6
Role of intraflagellar transport in transcriptional control during flagellar regeneration in Chlamydomonas	6
Dishevelled controls bulk cadherin dynamics and the stability of individual cadherin clusters during convergent extension	6
Damage–repair events increase the instability of cortical microtubules in Arabidopsis	6
Inclusivity in cell biology: cultural identity and the power of authenticity	6
From pipette to palette: Bridging science and art at MBoC	6