Molecular Biology of the Cell

Papers
(The TQCC of Molecular Biology of the Cell is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Suppression of cofilin-1 promotes invasion in 3D hyaluronic acid matrices by promoting actin-based protrusions68
Nonmuscle myosin IIA (NMIIA) regulates anisotropic cell tension to maintain the hexagonal packing of mouse lens meridional row cells62
Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia51
STMND1 is a phylogenetically ancient stathmin which localizes to motile cilia and exhibits nuclear translocation that is inhibited when soluble tubulin concentration increases47
Tubulin Acetylation Deficiency Promotes Axonemal Turnover and Increases Cytoplasmic Microtubules45
Preprint Highlight: Multiplexed bioluminescence microscopy via phasor analysis40
Preprint Highlight: Mitotic clustering of pulverized chromosomes from micronuclei37
Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 237
Mga2-mediated transcription supports mitotic nuclear expansion under lipid saturation conditions in stearoyl-CoA desaturase Ole1 mutant35
Hydrostatic pressure from basal side promotes cancer proliferation, enhances migration, and alters cell polarity: A model of the effects of interstitial fluid pressure in tumor microenvironment31
Sec18 binds the tethering/SM complex HOPS to engage the Qc-SNARE for membrane fusion31
The outer kinetochore components KNL-1 and Ndc80 complex regulate axon and neuronal cell body positioning in the C. elegans nervous system30
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic30
A role for Keratin 17 in Rac1-mediated DNA damage response in keratinocytes30
After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells29
Systematic evaluation of tools for auxin-inducible protein degradation in budding yeast28
Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence27
Mitotic spindle membranes27
Actin contraction controls nuclear blebbing and rupture independent of actin confinement27
p97/VCP Promotes the Recycling of Endocytic Cargo26
Load adaptation by endocytic actin networks26
David Baltimore and the advent of eukaryotic RNA-binding proteins26
Image-based discrimination of the early stages of mesenchymal stem cell differentiation26
Landmarks in the discovery of a role for actin in cell locomotion25
Preprint Highlight: Self‐supervised deep learning encodes high-resolution features of protein subcellular localization24
From pipette to palette: Bridging science and art at MBoC24
Preprint Highlight: Dynamic interplay of protrusive microtubule and contractile actomyosin forces drive tissue extension23
Preprint Highlight: Vimentin intermediate filaments organize organellar ER architecture in response to stress23
Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility23
Osh-dependent and -independent Regulation of PI4P Levels During Polarized Growth ofSaccharomyces cerevisiae23
Cell Painting predicts impact of lung cancer variants23
Preprint Highlight: Contractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis23
A mathematical model of calcium signals around laser-induced epithelial wounds23
Big1 is a newly identified autophagy regulator that is critical for a fully functional V-ATPase22
Calcium-binding Cab45 regulates the polarized apical secretion of soluble proteins in epithelial cells22
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding22
A modified motor-clutch model reveals that neuronal growth cones respond faster to soft substrates22
The nuclear isoforms of the Fragile X mental retardation RNA-binding protein associate with genomic DNA bridges21
Heterologous expression of Dictyostelium discoideum NE81 in mouse embryo fibroblasts reveals conserved mechanoprotective roles of lamins21
FHOD-1 and profilin protect sarcomeres against contraction-induced deformation> in C. elegans21
EHD2 regulates plasma membrane integrity and downstream insulin receptor signaling events21
Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins21
LYSET facilitates integration of both the N- and C-terminal transmembrane helices/cytoplasmic domains of GlcNAc-1-phosphotransferase21
Insights into the role of Nup62 and Nup93 in assembling cytoplasmic ring and central transport channel of the nuclear pore complex21
Delamination of epithelia induced by air–liquid interfaces21
Cell type- and transcription-independent spatial proximity between enhancers and promoters20
DAmFRET measures saturating concentrations and toxicities of protein phase transitions in vivo20
The SNARE-associated protein Sft2 functions in Imh1-mediated SNARE recycling transport upon ER stress20
Scaling of biosynthesis and metabolism with cell size20
Membrane lipids couple synaptotagmin to SNARE-mediated granule fusion in insulin-secreting cells20
The initiation and early development of the tubulin-containing cytoskeleton in the human parasite Toxoplasma gondii20
HSPA8 inhibitors augment cancer chemotherapeutic effectiveness via potentiating necroptosis20
Cytoplasmic preassembly of the flagellar outer dynein arm complex in Trypanosoma brucei19
The biophysical mechanism of mitochondrial pearling19
Lgd regulates ESCRT-III complex accumulation at multivesicular endosomes to control intralumenal vesicle formation19
Intracellular diffusion in the cytoplasm increases with cell size in fission yeast19
Regulation of misfolded protein aggregation and degradation by SUMOylation in budding yeast19
The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential19
Characterization of Orsay virus replication intermediates in Caenorhabditis elegans reveals links to antiviral RNA interference19
Atypical and distinct microtubule radial symmetries in the centriole and the axoneme of Lecudina tuzetae19
MotiQ: an open-source toolbox to quantify the cell motility and morphology of microglia19
A system for high-throughput axonal imaging of induced pluripotent stem cell-derived human i 3 Neurons19
Orchestrating nonmuscle myosin II filament assembly at the onset of cytokinesis19
Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division19
Regulation of membrane scission in yeast endocytosis19
Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells18
The Rab11-family interacting proteins reveal selective interaction of mammalian recycling endosomes with the Toxoplasma parasitophorous vacuole in a Rab118
Spatiotemporal analysis of F-actin polymerization with micropillar arrays reveals synchronization between adhesion sites18
Plectin linkages are mechanosensitive and required for the nuclear piston mechanism of three-dimensional cell migration18
The Kinesin-14 tail: Dual microtubule binding domains drive spindle morphogenesis through tight microtubule cross-linking and robust sliding17
YeastSAM: A Deep Learning Model for Accurate Segmentation of Yeast Cells17
Preexisting tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia17
Visualization of the three-dimensional structure of the human centromere in mitotic chromosomes by superresolution microscopy17
Practical guide to fluorescence lifetime imaging microscopy17
LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis17
Nucleoli in epithelial cell collectives respond to tumorigenic, spatial, and mechanical cues17
Mechanisms underlying Myosin 10′s contribution to the maintenance of mitotic spindle bipolarity17
Cell segregation via differential collision modes between heterotypic cell populations16
Breaking the rules of cell biology: Lessons from the liver's exceptional regenerative capacity16
Multiple tethers of organelle contact sites are involved in α-synuclein toxicity in yeast16
Serotonin 5-HT7 receptor slows down the Gs protein: a single molecule perspective16
Ehg1/May24 stabilizes yeast amino acid permease by facilitating its localization to lipid rafts under high hydrostatic pressure16
FOXO nuclear shuttling dynamics are stimulus-dependent and correspond with cell fate16
Preprint Highlight: Real-time denoising of fluorescence time-lapse imaging enables high-sensitivity observations of biological dynamics beyond the shot-noise limit16
Combining multiple fluorescence imaging techniques in biology: when one microscope is not enough16
Correction for Angiotensin II down-regulates nephrinAkt signaling and induces podocyte injury: role of c-Abl15
Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization15
Tools for live-cell imaging of cytoskeletal and nuclear behavior in the unconventional yeast, Aureobasidium pullulans15
Activation of the ChvG–ChvI pathway promotes survival during cell wall stress in Agrobacterium tumefaciens15
p115RhoGEF activates RhoA to support tight junction maintenance and remodeling15
Interaction of the sorting nexin 25 homologue Snazarus with Rab11 balances endocytic and secretory transport and maintains the ultrafiltration diaphragm in nephrocytes15
Actin and vimentin jointly control cell viscoelasticity and compression stiffening15
2022 ASCB Annual Meeting abstracts15
The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration15
Remodeling of cytoskeleton, chromatin, and gene expression during mechanical rejuvenation of aged human dermal fibroblasts15
Outer-arm dynein light chain LC1 is required for normal motor assembly kinetics, ciliary stability, and motility15
Modification of the neck-linker of KIF18A alters Microtubule subpopulation preference15
Distinct peroxisome populations differentially respond to alcohol-associated hepatic injury15
Antiparallel microtubule bundling supports KIF15-driven mitotic spindle assembly14
Celebrating women in academia and addressing underrepresentation14
Loss of intermicrovillar adhesion factor CDHR2 impairs basolateral junctional complexes in transporting epithelia14
Complex state transitions of the bacterial cell division protein FtsZ14
DLC-1 facilitates germ granule assembly in Caenorhabditis elegans embryo14
Innate immune cross-talk: The central role of neutrophils and macrophages in ANCA-associated vasculitis14
Temporal control of contact site formation reveals a relationship between mitochondrial division and Num1-mediated mitochondrial tethering14
A cross-species analysis of cell wall mechanosensors14
Drosophila Fog/Cta and T48 pathways have overlapping and distinct contributions to mesoderm invagination14
The mammalian class IX myosins Myo9a and Myo9b use different cellular actin assemblies for force production and regulation of Rho activity14
Phospholipase D1 produces phosphatidic acid at sites of secretory vesicle docking and fusion14
Septin organization is regulated by the Gpa1 ubiquitination domain and endocytic machinery during the yeast pheromone response14
Preprint Highlight: Deciphering the tumor-specific immunopeptidome in vivo with genetically engineered mouse models13
Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis13
A role for the kinetochore protein, NUF2, in ribosome biogenesis13
Preprint Highlight: The novel Rab5 effector FERRY links early endosomes with the translation machinery13
Role of Gα–MAPK interaction in mating of Saccharomyces cerevisiae13
Independence of centromeric and pericentromeric chromatin stability on CCAN components13
Loss of CHMP2A implicates an ordered assembly of ESCRT-III proteins during cytokinetic abscission13
Endothelial tip/stalk cell selection requires BMP9-induced βIV-spectrin expression during sprouting angiogenesis13
The role of neurofilament transport in the radial growth of myelinated axons13
Preprint Highlight: Probing the rules of cell coordination in live tissues by interpretable machine learning based on graph neural networks13
The Drosophila spectraplakin Short stop regulates focal adhesion dynamics by cross-linking microtubules and actin13
WAVE facilitates polarized E-cadherin transport13
Neuronal membrane proteasome-derived peptides modulate NMDAR-dependent neuronal signaling to promote changes in gene expression13
A multiparametric activity profiling platform for neuron disease phenotyping and drug screening13
Imaging-based screen identifies novel natural compounds that perturb cell and chloroplast division in Chlamydomonas reinhardtii13
Preprint Highlight: FLAgellum Member 8 modulates extravascular trypanosome distribution in the mammalian host13
Growth cone macropinocytosis of neurotrophin receptor and neuritogenesis are regulated by neuron navigator 113
The TOG5 domain of CKAP5 is required to interact with F-actin and promote microtubule advancement in neurons12
RAD51 regulates eukaryotic chromatin motions in the absence of DNA damage12
The RhoGAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle12
Nucleolar structure connects with global nuclear organization12
Polymer dynamics of Alp7A reveals how two critical concentrations govern assembly of dynamically unstable actin-like proteins12
WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration12
Transient PP2A SIP complex localization to mitotic SPBs for SIN inhibition is mediated solely by the Csc1 FHA domain12
Nkd1 functions downstream of Axin2 to attenuate Wnt signaling12
The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation12
Loss of negative regulation by HDAC1 and REST contributes to MAD1 overexpression in breast cancer12
Recruitment of the lipid kinase Mss4 to the meiotic spindle pole promotes prospore membrane formation in Saccharomyces cerevisiae12
Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells12
Identification of a Golgi-localized peptide reveals a minimal Golgi-targeting motif11
Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei11
Quantitative analysis of morphogenesis and growth dynamics in an obligate intracellular bacterium11
Preprint Highlight: LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia via Transcription Factor E3 Inhibition11
In vivo imaging reveals independent intraflagellar transport of the nexin–dynein regulatory complex subunits DRC2 and DRC411
Nanotopography modulates cytoskeletal organization and dynamics during T cell activation11
How many authors does it take to publish a high profile or classic paper?11
Scaling of nuclear numbers and their spatial arrangement in skeletal muscle cell size regulation11
Systematic analysis of microtubule plus-end networks defines EB-cargo complexes critical for mitosis in budding yeast11
Plasma membrane protrusions mediate host cell–cell fusion induced by Burkholderia thailandensis11
Dynein-dependent collection of membranes defines the architecture and position of microtubule asters in isolated, geometrically confined volumes of cell-free extracts11
Results from the MBoC Preprint Highlight experiment11
A new subset of mitochondrial-derived vesicles perform inter-mitochondrial communications11
A novel tool for the unbiased characterization of epithelial monolayer development in culture11
Strained actin binding by the Prickle2 LIM domains and their regulation in the full-length protein11
A role for Nup153 in nuclear assembly reveals differential requirements for targeting of nuclear envelope constituents11
Polymer models reveal how chromatin modification can modulate force at the kinetochore11
Automated segmentation of soft X-ray tomography: Native cellular structure with submicron resolution at high-throughput for whole-cell quantitative imaging in yeast11
Mutation of the PEBP-like domain of the mitoribosomal MrpL35/mL38 protein results in production of nascent chains with impaired capacity to assemble into OXPHOS complexes11
Fission yeast Pdk1 kinase regulates cytokinesis and eisosomes11
The roles of yeast formins and their regulators Bud6 and Bil2 in the pheromone response11
Preprint Highlight: PGC1α regulates the endothelial response to fluid shear stress via telomerase reverse transcriptase control of heme oxygenase‐111
CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis11
Recruitment of PI4KIIIβ to the Golgi by ACBD3 is dependent on an upstream pathway of a SNARE complex and golgins11
Preprint Highlight: Actomyosin cables position cell cohorts during Drosophila germband retraction by entraining their morphodynamic and mechanical properties10
Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization10
Dishevelled controls bulk cadherin dynamics and the stability of individual cadherin clusters during convergent extension10
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation10
Membrane fusion by Drosophila atlastin does not require GTP hydrolysis10
Superresolution microscopy reveals actomyosin dynamics in medioapical arrays10
Linear Z-line-like alignment of capping protein in obliquely striated muscle of the nematode C. elegans suggests that dense bodies are not equivalent to 10
VAC14 oligomerization is essential for the function of the FAB1/PIKfyve–VAC14–FIG4 complex10
A methodology for specific disruption of microtubule polymerization into dendritic spines10
Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants10
Preprint Highlight: Detyrosination enrichment on microtubule subsets is established by the interplay between a stochastically acting enzyme and microtubule stability10
Traveling-wave chemotaxis of neutrophil-like HL-60 cells10
Breaking the annotation barrier: An initial subcellular localization atlas of Giardia ’s hypothetical and conserved hypothetical proteins provides a reso10
Trafficking of K63-polyubiquitin–modified membrane proteins in a macroautophagy-independent pathway is linked to ATG9A10
Did axons evolve by activating cytokinesis during interphase? A hypothesis on the origin of neurons10
Maximizing Access to Cell Biology for PEERS: Retracting the term minority in favor of a more inclusive lexicon10
Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates10
Basal autophagy during meiotic prophase I is required for accurate chromosome segregation in Drosophila oocytes and declines during oocyte aging10
Diffusion within the synaptonemal complex can account for signal transduction along meiotic chromosomes10
Preprint Highlight: Transcriptomic changes highly similar to Alzheimer's disease are observed in a subpopulation of individuals during normal brain aging10
FAZ assembly in bloodstream form Trypanosoma brucei requires kinesin KIN-E10
A dedicated cytoplasmic container collects extrachromosomal DNA away from the mammalian nucleus10
Ultrastructure of COPII vesicle formation in yeast characterized by correlative light and electron microscopy10
Myosin F controls actin organization and dynamics in Toxoplasma gondii9
Enabled primarily controls filopodial morphology, not actin organization, in the TSM1 growth cone inDrosophila9
Molecular features and clinical significance of cancer-associated fibroblasts in colorectal cancer9
Preprint Highlight: Disruption of lactate metabolism in the peripheral nervous system leads to motor selective deficits9
The unfolded protein response of the endoplasmic reticulum supports mitochondrial biogenesis by buffering nonimported proteins9
Dysregulation of ceramide metabolism causes phytoceramide-dependent induction of the unfolded protein response9
FAP20 is required for flagellum assembly in Trypanosoma brucei9
Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids9
The lipid droplet protein Jabba promotes actin remodeling downstream of prostaglandin signaling during Drosophila oogenesis9
Inhibition of the chromatin remodeling factor NURF rescued sterility by a clinic variant of NuRD9
The DEAD-box RNA helicase DDX28 suppresses cell migration and 3D growth and invasion in MDA-MB-231 cells by altering bioenergetics9
Isoform-specific phosphorylation of axonemal dynein heavy chains9
Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif9
Preprint Highlight: The mechanosensitive ion channel Piezo mediates Rho activation and actin stress fibre formation in Drosophila nephrocytes9
Preprint Highlight: Learning orientation-invariant representations enables accurate and robust morphologic profiling of cells and organelles9
Three types of actomyosin rings within a common cytoplasm exhibit distinct modes of contractility9
Michael Patrick Sheetz, 1946–2025, a devotee of and major contributor to membrane and cytoskeletal biology9
Correction for Article Title “The laforin-malin complex, involved in Lafora disease, promotes the incorporation of K63-linked ubiquitin chains into AMP-activated protein kinase beta subunits”.9
Large-scale mapping of positional changes of hypoxia-responsive genes upon activation9
Solo regulates the localization and activity of LARG for actin cytoskeletal remodeling in cell-substrate adhesions9
A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly9
The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes9
Evidence for novel mechanisms that control cell-cycle entry and cell size9
Powering morphogenesis: multiscale challenges at the interface of cell adhesion and the cytoskeleton9
VAMP2 and synaptotagmin mobility in chromaffin granule membranes: implications for regulated exocytosis9
Membrane stretching activates calcium permeability of a putative channel Pkd2 during fission yeast cytokinesis9
M phase–specific generation of supernumerary centrioles in cancer cells9
A PACAP-activated network for secretion requires coordination of Ca 2+ influx and Ca 2+ mobilizati9
Differentiation-dependent changes in lamin B1 dynamics and lamin B receptor localization9
Septins associate with AP-3 to support trafficking to the vacuole/lysosome in yeast9
VAMP5 promotes Fcγ receptor-mediated phagocytosis and regulates phagosome maturation in macrophages9
Cilia.Pro database of ciliary proteins from vertebrates, Chlamydomonas , and Caenorhabditis9
Inositol 1, 4, 5-trisphosphate receptor is required for spindle assembly in Xenopus oocytes9
Remarkable chromosomes and karyotypes: A top 10 list9
The [PSI+] prion modulates cytochrome c oxidase deficiency caused by deletion of COX129
AP-4 regulates neuronal lysosome composition, function, and transport via regulating export of critical lysosome receptor proteins at the trans-Golgi network9
Med13 is required for efficient P-body recruitment and autophagic degradation of Edc3 following nitrogen starvation8
Mechanical strategies supporting growth and size diversity in Filamentous Fungi8
A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase8
Polarized anionic phospholipids and exocytosis are implicated in the polarized recruitment of budding yeast AP180, an endocytic initiator8
On the inference of ERK signaling dynamics from protein biosensor measurements8
Parkinson disease–associated toxic exposures selectively up-regulate vesicular glutamate transporter vGlut2 in a model of human cortical neurons8
The RhoGEF Trio regulates the formation of tensile linear endothelial junctions to improve barrier function8
MARVEL domain containing CMTM4 affects CXCR4 trafficking8
SEL1L regulates ER homeostasis in Sertoli cells but is dispensable for their function8
SPAK-dependent cotransporter activity mediates capillary adhesion and pressure during glioblastoma migration in confined spaces8
Ras-mediated activation of mTORC2 promotes breast epithelial cell migration and invasion8
The myosin chaperone UNC-45 has an important role in maintaining the structure and function of muscle sarcomeres during adult aging8
Novel cryo-tomography workflow reveals nanometer-scale responses of epithelial cells to matrix stiffness and dimensionality8
Functional fluorescence labeling of actins in live-cell system using engineered split-GFP technology8
Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA8
Preprint Highlight: Cell adhesions link subcellular actomyosin dynamics to tissue-scale-force production during vertebrate convergent extension8
Tubulin CFEOM mutations both inhibit or activate kinesin motor activity8
Quantitative fluorescence emission anisotropy microscopy for implementing homo–fluorescence resonance energy transfer measurements in living cells8
CD56/NCAM mediates cell migration of human NK cells by promoting integrin-mediated adhesion turnover8
Time-resolved cryogenic electron tomography for the study of transient cellular processes8
Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites8
The C-terminus of α-Synuclein Regulates its Dynamic Cellular Internalization by Neurexin 1β8
Endosome maturation during ER stress relies on the ubiquitin-binding domain of histone deacetylase 68
Cytoplasmic keratins couple with and maintain nuclear envelope integrity in colonic epithelial cells8
Lipid droplets are rigid and physically suppress phagocytosis, unless cell compression or stretching activates actomyosin8
Evidence of kinesin motors involved in stable kinetochore assembly during early meiosis8
Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin8
MRE11-independent effects of Mirin on mitochondrial DNA integrity and cellular immune responses8
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