OOIR: Observatory of International Research

Papers

(The TQCC of Osteoarthritis and Cartilage is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Macrophages regulate the progression of osteoarthritis	245
Epidemiology of osteoarthritis	214
Osteoarthritis year in review 2021: epidemiology & therapy	171
The role of macrophages in osteoarthritis and cartilage repair	144
Osteoarthritis year in review 2020: biology	108
Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis	102
Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD)	100
The burden of OA-health services and economics	97
Roles of NLRP3 inflammasome in intervertebral disc degeneration	89
Osteoarthritis year in review 2020: epidemiology & therapy	80
Identifying effector molecules, cells, and cytokines of innate immunity in OA	67
The causal role of gut microbiota in development of osteoarthritis	66
Osteoarthritis year in review 2021: biology	65
Single-cell RNA-seq analysis identifies unique chondrocyte subsets and reveals involvement of ferroptosis in human intervertebral disc degeneration	65
The innate immune response as a mediator of osteoarthritis pain	62
How does hip osteoarthritis differ from knee osteoarthritis?	58
The compartmental distribution of knee osteoarthritis – a systematic review and meta-analysis	55
The role of structure and function changes of sensory nervous system in intervertebral disc-related low back pain	54
Genetics of osteoarthritis	54
Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization	54
Osteoarthritis year in review: genetics, genomics, epigenetics	49
A Phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis	47
Immediate outcomes following the GLA:D® program in Denmark, Canada and Australia. A longitudinal analysis including 28,370 patients with symptomatic knee or hip osteoarthritis	46
A lifespan approach to osteoarthritis prevention	46
Fundamentals of OA. An initiative of Osteoarthritis and Cartilage. Obesity and metabolic factors in OA	45

Osteoarthritis year in review 2020: rehabilitation and outcomes	44
Association between knee inflammation and knee pain in patients with knee osteoarthritis: a systematic review	43
The effects of TNF-alpha inhibition on cartilage: a systematic review of preclinical studies	43
Melatonin activates autophagy via the NF-κB signaling pathway to prevent extracellular matrix degeneration in intervertebral disc	42
MFN2 contributes to metabolic disorders and inflammation in the aging of rat chondrocytes and osteoarthritis	42
tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via AGO-dependent mechanism in IL-1β stimulated chondrocytes	41
Systematic review and meta-analysis of the prevalence of neuropathic-like pain and/or pain sensitization in people with knee and hip osteoarthritis	40
Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental temporomandibular joint osteoarthritis	40
The role of stromal cell-derived factor 1 on cartilage development and disease	39
Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis	39
Are education, exercise and diet interventions a cost-effective treatment to manage hip and knee osteoarthritis? A systematic review	39
Activation of TRPV4 by mechanical, osmotic or pharmaceutical stimulation is anti-inflammatory blocking IL-1β mediated articular cartilage matrix destruction	38
Targeting STING attenuates ROS induced intervertebral disc degeneration	37
Pharmaceutical treatment of osteoarthritis	36
Lysosomal dysfunction in osteoarthritis and aged cartilage triggers apoptosis in chondrocytes through BAX mediated release of Cytochrome c	35
Is hip morphology a risk factor for developing hip osteoarthritis? A systematic review with meta-analysis	34
Comparison of joint degeneration and pain in male and female mice in DMM model of osteoarthritis	34
The diagnostic value of conventional radiography and musculoskeletal ultrasonography in calcium pyrophosphate deposition disease: a systematic literature review and meta-analysis	34
Patient preferences for osteoarthritis pain and chronic low back pain treatments in the United States: a discrete-choice experiment	32
CCL3/CCR1 mediates CD14+CD16− circulating monocyte recruitment in knee osteoarthritis progression	32
A neural network to predict the knee adduction moment in patients with osteoarthritis using anatomical landmarks obtainable from 2D video analysis	31
Intra-articular depletion of macrophages increases acute synovitis and alters macrophage polarity in the injured mouse knee	31
Visual Analogue Scale has higher assay sensitivity than WOMAC pain in detecting between-group differences in treatment effects: a meta-epidemiological study	31
Early stage blockade of the alarmin HMGB1 reduces cartilage destruction in experimental OA	31
Cardiometabolic traits mediating the effect of education on osteoarthritis risk: a Mendelian randomization study	31
Initiation and progression of dental-stimulated temporomandibular joints osteoarthritis	30
Osteoarthritis in year 2021: biochemical markers	30
Comparative efficacy and safety of acetaminophen, topical and oral non-steroidal anti-inflammatory drugs for knee osteoarthritis: evidence from a network meta-analysis of randomized controlled trials	29
Genetically predicted circulating levels of copper and zinc are associated with osteoarthritis but not with rheumatoid arthritis	29
High-fat feeding primes the mouse knee joint to develop osteoarthritis and pathologic infrapatellar fat pad changes after surgically induced injury	28
Mitochondrial quality control in cartilage damage and osteoarthritis: new insights and potential therapeutic targets	28
Inflammation and joint destruction may be linked to the generation of cartilage metabolites of ADAMTS-5 through activation of toll-like receptors	28
Cannabinoid receptor type 2 is upregulated in synovium following joint injury and mediates anti-inflammatory effects in synovial fibroblasts and macrophages	28
The relation between the biochemical composition of knee articular cartilage and quantitative MRI: a systematic review and meta-analysis	28
Rhoifolin ameliorates osteoarthritis via the Nrf2/NF-κB axis: in vitro and in vivo experiments	27
MMP-9 mediated Syndecan-4 shedding correlates with osteoarthritis severity	27
Multi-vendor multi-site T1ρ and T2 quantification of knee cartilage	27
Estimating contextual effect in nonpharmacological therapies for pain in knee osteoarthritis: a systematic analytic review	27
Assessment of quantitative [18F]Sodium fluoride PET measures of knee subchondral bone perfusion and mineralization in osteoarthritic and healthy subjects	27
Efficacy and safety of duloxetine in osteoarthritis or chronic low back pain: a Systematic review and meta-analysis	27
Systemic iron overload exacerbates osteoarthritis in the strain 13 guinea pig	26
The prevalence of radiographic thumb base osteoarthritis: a meta-analysis	26
Fecal metabolomics reveals products of dysregulated proteolysis and altered microbial metabolism in obesity-related osteoarthritis	26
Contribution of nerves within osteochondral channels to osteoarthritis knee pain in humans and rats	26
Proportion and associated factors of meeting the 2018 Physical Activity Guidelines for Americans in adults with or at risk for knee osteoarthritis	26
Exploring the relationship between chronic pain and cortisol levels in subjects with osteoarthritis: results from a systematic review of the literature	26
Degeneration alters the biomechanical properties and structural composition of lateral human menisci	26
Identification of human temporomandibular joint fibrocartilage stem cells with distinct chondrogenic capacity	25
Identification of tissue-dependent proteins in knee OA synovial fluid	25
Multi-tissue epigenetic analysis of the osteoarthritis susceptibility locus mapping to the plectin gene PLEC	25

Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis	25
Osteoarthritis year in review: genetics, genomics, epigenetics	25
Imaging in Osteoarthritis	25
What type of exercise is most effective for people with knee osteoarthritis and co-morbid obesity?: The TARGET randomized controlled trial	25
Microarray analyses of the dorsal root ganglia support a role for innate neuro-immune pathways in persistent pain in experimental osteoarthritis	24
Quantitative sensory testing: identifying pain characteristics in patients with osteoarthritis	24
OA foundations – experimental models of osteoarthritis	24
Disentangling contextual effects from musculoskeletal treatments	24
Burden of osteoarthritis in India and its states, 1990–2019: findings from the Global Burden of disease study 2019	23
Inhibition of LRRK2 restores parkin-mediated mitophagy and attenuates intervertebral disc degeneration	23
Individuals with mild-to-moderate hip osteoarthritis walk with lower hip joint contact forces despite higher levels of muscle co-contraction compared to healthy individuals	23
Statistical shape modeling of the hip and the association with hip osteoarthritis: a systematic review	23
Mitochondrial biogenesis: a potential therapeutic target for osteoarthritis	23
Linc-ROR promotes mesenchymal stem cells chondrogenesis and cartilage formation via regulating SOX9 expression	23
Differentiated activities of decorin and biglycan in the progression of post-traumatic osteoarthritis	22
Alpha defensin-1 attenuates surgically induced osteoarthritis in association with promoting M1 to M2 macrophage polarization	22
The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence	22
Are biomechanics during gait associated with the structural disease onset and progression of lower limb osteoarthritis? A systematic review and meta-analysis	22
Joint synovial macrophages as a potential target for intra-articular treatment of osteoarthritis-related pain	22
Role of TLR2 and TLR4 in regulation of articular chondrocyte homeostasis	22
Flare-ups of osteoarthritis: what do they mean in the short-term and the long-term?	22
Osteoarthritis year in review 2022: biology	22
Novel biomarkers of intervertebral disc cells and evidence of stem cells in the intervertebral disc	22
Cellular therapy and tissue engineering for cartilage repair	21
Development of osteoarthritis in patients with degenerative meniscal tears treated with exercise therapy or surgery: a randomized controlled trial	21
Oral administration of berberine limits post-traumatic osteoarthritis development and associated pain via AMP-activated protein kinase (AMPK) in mice	21
ERK1/2-mediated activation of DRP1 regulates mitochondrial dynamics and apoptosis in chondrocytes	21
Metabolic osteoarthritis – relation of diabetes and cardiovascular disease with knee osteoarthritis	21
Surgical therapy in osteoarthritis	21
Prevalence of early hip OA features on MRI in high-impact athletes. The femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study	20
Adaptive segmentation of knee radiographs for selecting the optimal ROI in texture analysis	20
Association of knee OA structural phenotypes to risk for progression: a secondary analysis from the Foundation for National Institutes of Health Osteoarthritis Biomarkers study (FNIH)	20
[18F]NaF PET-MRI provides direct in-vivo evidence of the association between bone metabolic activity and adjacent synovitis in knee osteoarthritis: a cross-sectional study	19
Leukocyte-dependent effects of platelet-rich plasma on cartilage loss and thermal hyperalgesia in a mouse model of post-traumatic osteoarthritis	19
Severity of intervertebral disc herniation regulates cytokine and chemokine levels in patients with chronic radicular back pain	19
Clinicians’ beliefs and attitudes to physical activity and exercise therapy as treatment for knee and/or hip osteoarthritis: a scoping review	19
Quantitative three-dimensional collagen orientation analysis of human meniscus posterior horn in health and osteoarthritis using micro-computed tomography	19
Osteoarthritis year in review 2021: mechanics	18
Osteoarthritis year in review 2022: Epidemiology & therapy	18
Colchicine is not effective for reducing osteoarthritic hand pain compared to placebo: a randomised, placebo-controlled trial (COLAH)	18
Evidence for causal effects of sleep disturbances on risk for osteoarthritis: a univariable and multivariable Mendelian randomization study	18
The association between walking speed from short- and standard-distance tests with the risk of all-cause mortality among adults with radiographic knee osteoarthritis: data from three large United Stat	18
The microbiome mediates epiphyseal bone loss and metabolomic changes after acute joint trauma in mice	18
Triggers for acute flare in adults with, or at risk of, knee osteoarthritis: a web-based case-crossover study in community-dwelling adults	18
Advances in organ-on-a-chip systems for modelling joint tissue and osteoarthritic diseases	18
Trajectory of excess healthcare consultations, medication use, and work disability in newly diagnosed knee osteoarthritis: a matched longitudinal register-based study	18
International Foot and Ankle Osteoarthritis Consortium review and research agenda for diagnosis, epidemiology, burden, outcome assessment and treatment	18
Association between changes in knee load and effusion-synovitis: evidence of mechano-inflammation in knee osteoarthritis using high tibial osteotomy as a model	18
Osteoarthritis year in review 2020: mechanics	18
A novel quantitative metric for joint space width: data from the Osteoarthritis Initiative (OAI)	18
Effect of exercise on pain processing and motor output in people with knee osteoarthritis: a systematic review and meta-analysis	18
Machine learning to predict incident radiographic knee osteoarthritis over 8 Years using combined MR imaging features, demographics, and clinical factors: data from the Osteoarthritis Initiative	17
Activation of innate immunity by 14-3-3 ε, a new potential alarmin in osteoarthritis	17
Inhibition of fibrotic changes in infrapatellar fat pad alleviates persistent pain and articular cartilage degeneration in monoiodoacetic acid-induced rat arthritis model	17
Transcriptional response of human articular chondrocytes treated with fibronectin fragments: an in vitro model of the osteoarthritis phenotype	17
Post-traumatic osteoarthritis progression is diminished by early mechanical unloading and anti-inflammatory treatment in mice	17
Proof-of-concept for the detection of early osteoarthritis pathology by clinically applicable endomicroscopy and quantitative AI-supported optical biopsy	17
Low levels of type II collagen formation (PRO-C2) are associated with response to sprifermin: a pre-defined, exploratory biomarker analysis from the FORWARD study	17
Effects of progressive resistance training prior to total HIP arthroplasty – a secondary analysis of a randomized controlled trial	17
Performance of the HOOS-12 and KOOS-12 instruments for evaluating outcomes from joint replacement surgery	17
Osteoarthritis year in review 2022: rehabilitation	17
Automated detection of patellofemoral osteoarthritis from knee lateral view radiographs using deep learning: data from the Multicenter Osteoarthritis Study (MOST)	17
N(6)-methyladenosine RNA methyltransferase like 3 inhibits extracellular matrix synthesis of endplate chondrocytes by downregulating sex-determining region Y-Box transcription factor 9 expression unde	17
Tyrosine kinases regulate chondrocyte hypertrophy: promising drug targets for Osteoarthritis	16
Circadian time series proteomics reveals daily dynamics in cartilage physiology	16
Association between statin use and incidence or progression of osteoarthritis: meta-analysis of observational studies	16
Are medical comorbidities contributing to the use of opioid analgesics in patients with knee osteoarthritis?	16
The emperor's new clothes?	16
Associations between comorbidities and immediate and one-year outcomes following supervised exercise therapy and patient education – A cohort study of 24,513 individuals with knee or hip osteoarthriti	16
NF-κB-mediated effects on behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis	16
Does preoperative neuropathic-like pain and central sensitisation affect the post-operative outcome of knee joint replacement for osteoarthritis? A systematic review and meta analysis	16
Osteoarthritis year in review 2020: imaging	16
Efficacy and safety of a supplement combination on hand pain among people with symptomatic hand osteoarthritis an internet-based, randomised clinical trial the RADIANT study	16
Complement component C1q is produced by isolated articular chondrocytes	16
Single cell transcriptomics in human osteoarthritis synovium and in silico deconvoluted bulk RNA sequencing	16
Regulation of inflammatory and catabolic responses to IL-1β in rat articular chondrocytes by microRNAs miR-122 and miR-451	16
gagCEST imaging at 3 T MRI in patients with articular cartilage lesions of the knee and intraoperative validation	16
Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma	15
Forward and reverse degradomics defines the proteolytic landscape of human knee osteoarthritic cartilage and the role of the serine protease HtrA1	15
Synovial fluid from end-stage osteoarthritis induces proliferation and fibrosis of articular chondrocytes via MAPK and RhoGTPase signaling	15

Optimization of histologic grading schemes in spontaneous and surgically-induced murine models of osteoarthritis	15
Fundamentals of osteoarthritis: outcome evaluation with patient-reported measures and functional tests	15
A phase 2, randomized, double-blind, placebo-controlled study of senolytic molecule UBX0101 in the treatment of painful knee osteoarthritis	15
Alarmins S100A8/A9 promote intervertebral disc degeneration and inflammation-related pain in a rat model through toll-like receptor-4 and activation of the NF-κB signaling pathway	15
Lubricin in experimental and naturally occurring osteoarthritis: a systematic review	15
Machine learning augmented near-infrared spectroscopy: In vivo follow-up of cartilage defects	15
Effects of recurrent intra-articular corticosteroid injections for osteoarthritis at 3 months and beyond: a systematic review and meta-analysis in comparison to other injectables	15
Heterogeneity of cartilage damage in Kellgren and Lawrence grade 2 and 3 knees: the MOST study	15
Subregional statistical shape modelling identifies lesser trochanter size as a possible risk factor for radiographic hip osteoarthritis, a cross-sectional analysis from the Osteoporotic Fractures in M	15
Cartilaginous endplate avulsion is associated with modic changes and endplate defects, and residual back and leg pain following lumbar discectomy	15
Individuals with high bone mass have increased progression of radiographic and clinical features of knee osteoarthritis	15
Three-dimensional analysis for quantification of knee joint space width with weight-bearing CT: comparison with non-weight-bearing CT and weight-bearing radiography	15
Differential patterns of pathology in and interaction between joint tissues in long-term osteoarthritis with different initiating causes: phenotype matters	15
The osteoarthritis bone score (OABS): a new histological scoring system for the characterisation of bone marrow lesions in osteoarthritis	14
Identification of a distinct lipidomic profile in the osteoarthritic synovial membrane by mass spectrometry imaging	14
TGFβ1 signaling protects chondrocytes against oxidative stress via FOXO1–autophagy axis	14
Synovial fluid concentrations of matrix Metalloproteinase-3 and Interluekin-6 following anterior cruciate ligament injury associate with gait biomechanics 6 months following reconstruction	14
Auto-antibodies to post-translationally modified proteins in osteoarthritis	14
Bromodomain-containing-protein-4 and cyclin-dependent-kinase-9 inhibitors interact synergistically in vitro and combined treatment reduces post-traumatic osteoarthritis severity in mice	14
Rodent models of knee osteoarthritis for pain research	14
Osteoarthritis Bone Marrow Lesions	14
Does moderate intensity impact exercise and non-impact exercise induce acute changes in collagen biochemical markers related to osteoarthritis? – An exploratory randomized cross-over trial	14
Recommendations for the management of hip and knee osteoarthritis: A systematic review of clinical practice guidelines	14
Dysregulated energy metabolism impairs chondrocyte function in osteoarthritis	14
The KNee OsteoArthritis Prediction (KNOAP2020) challenge: An image analysis challenge to predict incident symptomatic radiographic knee osteoarthritis from MRI and X-ray images	14
Cross-talk of inflammation and chondrocyte intracellular metabolism in osteoarthritis	13
Extracellular vesicles derived from mesenchymal stem cells confer protection against intervertebral disc degeneration through a microRNA-217-dependent mechanism	13
A clinical model including protein biomarkers predicts radiographic knee osteoarthritis: a prospective study using data from the Osteoarthritis Initiative	13
The E3 ubiquitin ligase Itch limits the progression of post-traumatic osteoarthritis in mice by inhibiting macrophage polarization	13
The impact of a significant weight loss on inflammation assessed on DCE-MRI and static MRI in knee osteoarthritis: a prospective cohort study	13
Human articular cartilage is orthotropic where microstructure, micromechanics, and chemistry vary with depth and split-line orientation	13
A novel placental tissue biologic, PTP-001, inhibits inflammatory and catabolic responses in vitro and prevents pain and cartilage degeneration in a rat model of osteoarthritis	13
Cam morphology but neither acetabular dysplasia nor pincer morphology is associated with osteophytosis throughout the hip: findings from a cross-sectional study in UK Biobank	13
“It's the single best thing I've done in the last 10 years”: a qualitative study exploring patient and dietitian experiences with, and perceptions of, a multi-component dietary weight loss program for	13
Cartilage calcification is associated with histological degeneration of the knee joint: a highly prevalent, age-independent systemic process	13
Cross-validation of good versus poor self-reported outcome trajectory types following knee arthroplasty	13
Stem cell-based therapies for temporomandibular joint osteoarthritis and regeneration of cartilage/osteochondral defects: a systematic review of preclinical experiments	13
Abnormal subchondral trabecular bone remodeling in knee osteoarthritis under the influence of knee alignment	13
Proteomic comparison of osteoarthritic and reference human menisci using data-independent acquisition mass spectrometry	13
Evaluating the impact of metformin targets on the risk of osteoarthritis: a mendelian randomization study	13
An altered heparan sulfate structure in the articular cartilage protects against osteoarthritis	13
The effect of hydrostatic pressure on proteoglycan production in articular cartilage in vitro: a meta-analysis	13
Critical appraisal of intra-articular glucocorticoid injections for symptomatic osteoarthritis of the knee	13
Cost-effectiveness of 12 weeks of supervised treatment compared to written advice in patients with knee osteoarthritis: a secondary analysis of the 2-year outcome from a randomized trial	12
Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation	12
Comparative effect of two educational videos on self-efficacy and kinesiophobia in people with knee osteoarthritis: an online randomised controlled trial	12
Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5	12
Ground reaction force patterns in knees with and without radiographic osteoarthritis and pain: descriptive analyses of a large cohort (the Multicenter Osteoarthritis Study)	12
Machine learning-augmented and microspectroscopy-informed multiparametric MRI for the non-invasive prediction of articular cartilage composition	12
Voluntary running attenuates behavioural signs of low back pain: dimorphic regulation of intervertebral disc inflammation in male and female SPARC-null mice	12
Effect of transcutaneous electrical nerve stimulation (TENS) on knee pain and physical function in patients with symptomatic knee osteoarthritis: the ETRELKA randomized clinical trial	12
Assessing causality between osteoarthritis with urate levels and gout: a bidirectional Mendelian randomization study	12
The relation of oral bisphosphonates to bone marrow lesion volume among women with osteoarthritis	12
Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells	12
Osteoarthritis and the incidence of fracture in the United Kingdom: a retrospective cohort study of 258,696 patients	12
Knee and hip osteoarthritis are more alike than different in baseline characteristics and outcomes: a longitudinal study of 32,599 patients participating in supervised education and exercise therapy	12
Individualized predictions of changes in knee pain, quality of life and walking speed following patient education and exercise therapy in patients with knee osteoarthritis – a prognostic model study	12
Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group	12
Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint	12
Effects of long-term exercise and a high-fat diet on synovial fluid metabolomics and joint structural phenotypes in mice: an integrated network analysis	11
Low-dose strength training in addition to neuromuscular exercise and education in patients with knee osteoarthritis in secondary care – a randomized controlled trial	11
Does smoking cessation increase risk of knee replacement? a general population-based cohort study	11
Macromolecular fraction (MMF) from 3D ultrashort echo time cones magnetization transfer (3D UTE-Cones-MT) imaging predicts meniscal degeneration and knee osteoarthritis	11
The relationship between meniscal pathologies, cartilage loss, joint replacement and pain in knee osteoarthritis: a systematic review	11
Deep learning enables the automation of grading histological tissue engineered cartilage images for quality control standardization	11
Effectiveness, safety, and cost–utility of a knee brace in medial knee osteoarthritis: the ERGONOMIE randomized controlled trial	11
The relationship between prescribed pre-operative knee-extensor exercise dosage and effect on knee-extensor strength prior to and following total knee arthroplasty: a systematic review and meta-regres	11
Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5	11
Metformin as a potential disease-modifying drug in osteoarthritis: a systematic review of pre-clinical and human studies	11
Administration of an adeno-associated viral vector expressing interferon-β in patients with inflammatory hand arthritis, results of a phase I/II study	11
Automating three-dimensional osteoarthritis histopathological grading of human osteochondral tissue using machine learning on contrast-enhanced micro-computed tomography	11
Automated MRI assessment confirms cartilage thickness modification in patients with knee osteoarthritis: post-hoc analysis from a phase II sprifermin study	11
Endothelin-1 induces chondrocyte senescence and cartilage damage via endothelin receptor type B in a post-traumatic osteoarthritis mouse model	11
Assessment of the efficacy of intra-articular platelet rich plasma treatment in an ACLT experimental model by dynamic contrast enhancement MRI of knee subchondral bone marrow and MRI T2 measurement o	11
Effective protein extraction combined with data independent acquisition analysis reveals a comprehensive and quantifiable insight into the proteomes of articular cartilage and subchondral bone	11
The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain	11
The cholinergic system in joint health and osteoarthritis: a narrative-review	11
Effectiveness of patient decision aids for total hip and knee arthroplasty decision-making: a systematic review	11
Physical activity thresholds for predicting longitudinal gait decline in adults with knee osteoarthritis	11
Systematic review and meta-analysis of measurement properties of the Hip disability and Osteoarthritis Outcome Score - Physical Function Shortform (HOOS-PS) and the Knee Injury and Osteoarthritis Outc	11
Shoe-stiffening inserts for first metatarsophalangeal joint osteoarthritis: a randomised trial	11
Evaluating the structural effects of intra-articular sprifermin on cartilage and non-cartilaginous tissue alterations, based on sqMRI assessment over 2 years	11
Spectroscopic photoacoustic imaging of cartilage damage	11
Foot structure and lower limb function in individuals with midfoot osteoarthritis: a systematic review	11
Soluble biomarkers in osteoarthritis in 2022: year in review	11
Changes of synovial fluid biomarker levels after opening wedge high tibial osteotomy in patients with knee osteoarthritis	11
Estimating incidence and prevalence of hip osteoarthritis using electronic health records: a population-based cohort study	11
Longitudinal changes in tibial and femoral cartilage thickness are associated with baseline ambulatory kinetics and cartilage oligomeric matrix protein (COMP) measures in an asymptomatic aging populat	11
Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin	11
Subchondral bone changes after joint distraction treatment for end stage knee osteoarthritis	10
Quantitative sensory testing in feline osteoarthritic pain – a systematic review and meta-analysis	10
Osteoarthritis & stroke: a bidirectional mendelian randomization study	10
Association of baseline and change in tibial and femoral cartilage thickness and development of widespread full-thickness cartilage loss in knee osteoarthritis – data from the Osteoarthritis Initiativ	10
Predicting knee replacement in participants eligible for disease-modifying osteoarthritis drug treatment with structural endpoints	10
The difference in joint instability affects the onset of cartilage degeneration or subchondral bone changes	10