Wound Repair and Regeneration

Article	Citations
Donepezil promotes skin flap survival through activation of the HIF‐1α/VEGF signalling pathway	212
Erratum	76
Issue Information	75
The heterogeneous wound microbiome varies with wound care pain, dressing type, and inflammatory gene expression	55
Performance of artificial intelligence chatbots in interpreting clinical images of pressure injuries	45
Cryogel wound dressings based on natural polysaccharides perfectly adhere to irregular wounds for rapid haemostasis and easy disassembly	44
A simplified method for monitoring cytokines in wound fluid	28
Patient and wound factors associated with WOUND‐Q scales measuring health‐related quality of life: An international cross‐sectional study	27
Fat Graft as Regenerative Treatment of Facial Manifestations of Systemic Sclerosis: A Systematic Review on the Role of Adipose Tissue‐Derived Stem Cells and on Surgical Outcomes to Define a New Standa	25
A collagen‐based layered chronic wound biofilm model for testing antimicrobial wound products	25
Interplay between epithelial and mesenchymal cells unveils essential proinflammatory and pro‐resolutive mediators modulated by photobiomodulation therapy at 660 nm	23
Issue Information	23
Current State‐Of‐Play of the EU Advanced Therapy Medicinal Product (ATMP) Field, With an Emphasis on Belgian Human Cell and Tissue Products	23
The Danish wound‐quality of life (Wound‐QoL) questionnaire: Translation and psychometric properties	23
52nd Annual Meeting of the Japanese Society for Wound Healing	21
Reviewers List	20
Issue Information	20
51st Annual Meeting of the Japanese Society for Wound Healing	20
Multimodal imaging device to comprehensively assess infection, oxygenation, and wound analytics—A pilot study	19
Research hotspot and trend of chronic wounds: A bibliometric analysis from 2013 to 2022	19
Basic haematological tests as inflammatory performance markers of patients treated either by conservative surgery or minor amputation for infected diabetic foot ulcers	19
Letter to editor in response to ‘Tian K, Ye J, Zhong Y, Jia Z, Xu W, Gao S, Cao S, Li K, Wu L. Autologous i‐PRF promotes healing of radiation‐induced skin injury. Wound Repair Regen. 2023;3	18
Skin metabolism in obesity: A narrative review	18
Polymicrobial infection in bone biopsies and relapse in diabetic foot osteomyelitis: The role of soft tissue involvement	17
The effect of quince seed mucilage on perineal pain and healing following episiotomy: A randomised, triple‐blind, placebo‐controlled study	17

Gradient expectations: Revisiting Charles Manning Child's theory of metabolic regionalisation in developmental patterning and regeneration	17
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A Matrix‐Derived Bioactive Peptide Enhances Epidermal Thickness and Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites	16
Relaxation intervention to improve diabetic foot ulcer healing: Results from a pilot randomized controlled study	16
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53rd Annual Meeting of the Japanese Society for Wound Healing	15
Effectiveness of Photobiomodulation and Exercise‐Based Rehabilitation on Pain and Functional Recovery in Patients With Rotator Cuff Pathology	14
A prospective, randomized, controlled clinical study on the effectiveness of a single‐use negative pressure wound therapy system, compared to traditional negative pressure wound therapy in the treatme	14
Validation and efficacy of ‘pure’ venous lymph node flap in a rat lymphoedema model	14
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Outcomes of open reduction and internal fixation of calcaneus fractures: A database study comparing patients with and without diabetes	13
What is slough? Defining the proteomic and microbial composition of slough and its implications for wound healing	13
Association of vaping with decreased vascular endothelial growth factor expression and decreased microvessel density in cutaneous wound healing tissue in rats	13
Valsartan nano‐filaments alter mitochondrial energetics and promote faster healing in diabetic rat wounds	13
Digital ulcers associated with scleroderma: A major unmet medical need	13
Nanomaterial interventions for wound healing: Current status of preclinical and clinical studies	12
Evaluating the cost‐effectiveness of diabetic foot ulcer management by wound care specialists in Indonesia	12
Keloids in male genitalia—Systematic review and illustrative case report	12
A story of fibers and stress: Matrix‐embedded signals for fibroblast activation in the skin	12
Topical vanadate improves tensile strength and alters collagen organisation of excisional wounds in a mouse model	11
Autologous i‐PRF promotes healing of radiation‐induced skin injury	11
List of Reviewers	11
Use of incisional preventive negative pressure wound therapy in open incisional hernia repair: Who benefits?	11
A role for vitamin D and the vitamin D receptor in keloid disorder	11
Investigation of the monocyte/high‐density lipoprotein ratio as a prognostic criterion in burn patients	11
Fibrosis: Sirtuins at the checkpoints of myofibroblast differentiation and profibrotic activity	10
Antibiotic‐loaded bone substitutes therapy in the management of the moderate to severe diabetic foot infection: A meta‐analysis	10
Therapeutic potential of silkworm sericin in wound healing applications	10
Animal models for the study of acute cutaneous wound healing	10
Monocyte and macrophage derived myofibroblasts: Is it fate? A review of the current evidence	10
Phenotypic characterisation and associations of leg ulcers in adult sickle cell patients	9
Issue Information	9
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A pro‐reparative bioelectronic device for controlled delivery of ions and biomolecules	9
Strengthening the Psychological Care of Patients With Diabetic Foot Complications	9
Evidence for the in vivo existence and mobilisation of myeloid angiogenic cells and pericyte‐like cells in wound patients after skin grafting	9
Pressure injuries and biofilms: Microbiome, model systems and therapies	9
Candidate Biomarkers for Hard‐to‐Heal Wounds Revealed by Single‐Cell RNA Sequencing of Wound Fluid in Murine Wound Models	8
Low‐temperature plasma jet suppresses bacterial colonisation and affects wound healing through reactive species	8
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Racial/ethnic disparities in chronic wounds: Perspectives on linking upstream factors to health outcomes	8
Minimising donor‐site morbidity following limbs' injuries with keystone perforator island flap reconstruction	8
3D‐printed electrospun fibres for wound healing	8
Pullulan‐Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings	8
Cytokine stability in chronic wound fluid and its association to fibroblast proliferation	8
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Evaluating the impact of an anti‐microbial silver‐impregnated surgical dressing on wound infections and healing: A randomised clinical trial	7
Clinical utility of67Gallium‐SPECT/CTfor determining osteotomy indication in patients with lower‐limb osteomyelitis	7
PI3K/AKT pathway promotes keloid fibroblasts proliferation by enhancing glycolysis under hypoxia	7
Comprehensive analysis of keloid vasculature by tissue clearing and 3D imaging	7

Healing profiles in patients with a chronic diabetic foot ulcer: An exploratory study with machine learning	7
Temporal microbiome changes in axolotl limb regeneration: Stage‐specific restructuring of bacterial and fungal communities with a Flavobacterium bloom during blastema proliferation	7
Risk factors associated with pressure ulcer recurrence after reconstruction: Analysis of a national database	7
Issue Information	7
Poly(lactide‐co‐ε‐caprolactone) scaffold promotes equivalent tissue integration and supports skin grafts compared to a predicate collagen scaffold	6
Antimicrobial peptide derived from insulin‐like growth factor‐binding protein 5 improves diabetic wound healing	6
Issue Information	6
Teleconsulting in wound care: Connecting the primary care to the wound specialist reduces unnecessary referrals	6
Issue Information	6
The myofibroblast and Giulio Gabbiani: An inseparable couple celebrates their 50 years golden wedding anniversary	6
Placenta‐derived mesenchymal stem cells promote diabetic wound healing via exosomal protein interaction networks	6
The paradigm of stem cell secretome in tissue repair and regeneration: Present and future perspectives	6
The effect of high‐voltage monophasic pulsed current on diabetic ulcers and their potential pathophysiologic factors: A systematic review and meta‐analysis	6
Issue Information	6
Safety and efficacy of treating post‐burn pathological scars with extracorporeal shock wave therapy: A meta‐analysis of randomised controlled trials	6
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Synergistic effects of incorporated additives in multifunctional dressings for chronic wound healing: An updated comprehensive review	6
Evaluation of factors affecting the healing process of venous ulcers: A 12‐week longitudinal study	5
Outcomes of dermal substitutes in burns and burn scar reconstruction: A systematic review and meta‐analysis	5
Comparative transcriptomic adaptations of Staphylococcus aureus to the wound environment in non‐diabetic and diabetic mice	5
Preclinical assessment of novel longer‐duration wear negative pressure wound therapy dressing in a porcine model	5
Anaerobic bacteria in chronic wounds: Roles in disease, infection and treatment failure	5
Severe diabetic foot infections without systemic inflammatory response syndrome: Prospective validation of a new category	5
Chronic wounds: Treatment consensus	5
In the face and neck, keloid scar distribution is related to skin thickness and stiffness changes associated with movement	5
Comparison of biopolymer scaffolds for the fabrication of skin substitutes in a porcine wound model	5
A recombinant signalling‐selective activated protein C that lacks anticoagulant activity is efficacious and safe in cutaneous wound preclinical models	5
Commentary on “Vitabiotic: An Alternative Approach to Diabetic Foot”	5
Autologous platelet‐rich fibrin as an adjunct to non‐surgical periodontal therapy—A follow up clinical pilot study	5
Animal experimental models of ischemic wounds – A review of literature	5
Full‐thickness skin columns: A method to reduce healing time and donor site morbidity in deep partial‐thickness burns	5
Role of haematopoietic cell‐specific protein 1‐associated protein X‐1 gene in lipopolysaccharide‐induced apoptosis of human dermal fibroblasts	5
Global Epidemiology, Burden, and Future Projections of Decubitus Ulcers: A Comprehensive Analysis From 1990 to 2050	4
Growth factors for treating chronic venous leg ulcers: A systematic review and meta‐analysis	4
Issue Information	4
Local problems need global solutions: The metabolic needs of regenerating organisms	4
3D skin bioprinting as promising therapeutic strategy for radiation‐associated skin injuries	4
Spectrum of diseases associated with pyoderma gangrenosum and correlation with effectiveness of therapy: New insights on the diagnosis and therapy of comorbid hidradenitis suppurativa	4
2024 WHS Abstract Session List Key	4
Issue Information	4
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Human keratin matrices promote wound healing by modulating skin cell expression of cytokines and growth factors	4
Cell‐free therapy based on stem cell‐derived exosomes: A promising approach for wound healing	4
Bromelain‐based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial	4
An overview of systematic reviews of clinical studies of platelet‐rich plasma for venous ulcers	4
Porcine‐derived collagen peptides promote re‐epithelialisation through activation of integrin signalling	4
The proliferative effects of stem cells from apical papilla‐conditioned medium on rat corneal endothelial cells	4
Further considerations on risk factors for re‐infection in diabetic foot osteomyelitis: Insights and recommendations for future research	4
A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimic	3
Prevalence and characteristics of pain in patients with lower‐extremity ulcers—A cross‐sectional study	3
Photobiomodulation promotes hair regeneration in injured skin by enhancing migration and exosome secretion of dermal papilla cells	3
A randomised, double‐blind, placebo‐controlled study to determine the analgesic efficacy, safety and tolerability of VPX638 administered topically to painful wounds	3
Oral Communications	3
Update of biomarkers to diagnose diabetic foot osteomyelitis: A meta‐analysis and systematic review	3
Impact of malodour on health‐related quality of life of patients with chronic wounds due to volatile organic compounds	3
Effects of a bioengineered allogeneic cellular construct on burn‐related macrophage phenotype	3
Fibroblast‐like synoviocytes: Role in synovial fibrosis associated with osteoarthritis	3
Bacteria in hypertrophic scars promote scar formation through HSBP1‐mediated autophagy	3
Suppression of TRIM72‐mediated endoplasmic reticulum stress facilitates FOXM1 promotion of diabetic ulcer healing	3
Downregulation of aquaporin 3 in patients with pemphigus vulgaris	3
Polyphenol hydroxytyrosol present olive oil improves skin wound healing of diabetic mice	3
Foamy macrophages potentially inhibit tuberculous wound healing by inhibiting the TLRs/NF‐κB signalling pathway	3
2025 WHS Abstract Session List Key	3
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Naturally Derived Biomaterial‐Based Microneedles With Microenvironment‐Response Potential for Diabetic Wound Healing	3
Skin fibrosis is accompanied by increased expression of secreted frizzled‐related protein‐2	3
An evaluation of the usability and durability of 3D printed versus standard suture materials	3
Improved outcomes in patients with diabetic foot ulcers despite of differences in baseline characteristics	3
Abstracts Oral Presentations ETRS‐WHS‐SKINTERM Congress 2024 in Amersfoort	3
Vitabiotic: An alternative approach to diabetic foot	3
Photoactivated rose bengal mitigates a fibrotic phenotype and improves cutaneous wound healing in full‐thickness injuries	3
Increased temperature at the healed area detected by thermography predicts recurrent pressure ulcers	3
A structural equation model predicts chronic wound healing time using patient characteristics and wound microbiome composition	3
THANKS TO OUR REVIEWERS	3
The impact of youth‐onset type 2 diabetes on postoperative wound healing complications	3
Indications for the use of dermal substitutes in patients with acute burns and in reconstructive surgery after burns: A systematic review	3
Mönckeberg's medial calcific sclerosis in diabetic and non‐diabetic foot infections	3
Metabolic mediators in the type 2 diabetes‐osteomyelitis pathway: Complementing clinical risk factors with genetic evidence	3
Manipulating the microbiome alters regenerative outcomes in Xenopus laevis tadpoles via lipopolysaccharide signalling	3
Histone lactylation regulates autophagy of hyperplastic scar fibroblasts by inhibiting the transcriptional activity of phosphatase and tensin homologue	3

Platelet‐Rich Fibrin Mediates Beneficial Effects on Adipose‐Derived Stem Cells via Increased Levels of Key Cytokines	2
Issue Information	2
Uterine scars after caesarean delivery: From histology to the molecular and ultrastructural level	2
Dysregulation of miR‐146a is associated with exacerbated inflammation, oxidative and endoplasmic reticulum stress in the progression of diabetic foot ulcer	2
Expression of Concern: The Effects of Zinc Supplementation on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: A Randomized, Double‐blind, Placebo‐controlled Trial	2
Photosensitizer‐loaded hydrogels: A new antibacterial dressing	2
The associations between diode laser (810 nm) therapy and chronic wound healing and pain relief: Light into the chronic wound patient's life	2
Investigating quality of life instrument measurement properties for adults with active venous leg ulcers: A systematic review	2
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Incidence of and risk factors for self‐load‐related and medical device‐related pressure injuries in critically ill patients: A prospective observational cohort study	2
Bacterial cellulose as an ideal potential treatment for burn wounds: A comprehensive review	2
Uncovering a prominent association between pyoderma gangrenosum and hidradenitis suppurativa	2
Akt activation‐dependent protective effect of wild ginseng adventitious root protein against UVA‐induced NIH‐3T3 cell damage	2
Isotonic medium treatment limits burn wound microbial colonisation and improves tissue repair	2
Association between venous leg ulcers and knee osteoarthritis: A Mendelian randomization study	2
The use of hyperbaric oxygen therapy in the treatment of hand crush injuries	2
Clinical efficacy and patients’ perception of virtual reality during wound care in adults: A systematic review with meta‐analysis of randomised clinical trials	2
Nanofibrous polycaprolactone/gelatin scaffold containing gold nanoparticles: Physicochemical and biological characterization for wound healing	2
Global insights into keloid formation: An international systematic review of regional genetic risk factors and commonalities	2
Differential impact of missed initial wound clinic visit on 6‐month wound healing by race/ethnicity among patients with chronic limb‐threatening ischemia	2
Assessing the role of wound debridement in pyoderma gangrenosum—A retrospective cohort study	2
Novel multi‐spectral short‐wave infrared imaging for assessment of human burn wound depth	1
2023 Annual Meeting of the Wound Healing Society SAWC‐Spring/WHS Joint Meeting	1
Issue Information	1
Healing of diabetic neuropathic foot ulcers receiving standard treatment in randomised controlled trials: A random effects meta‐analysis	1
Protecting human amnion and chorion matrices during processing: Performance enhancement in a diabetic mouse model and human co‐culture system	1
To regenerate or not to regenerate: Vertebrate model organisms of regeneration‐competency and ‐incompetency	1
Iliac vein recanalisation and stenting accelerate healing of venous leg ulcers associated with severe venous outflow obstruction	1
Intervention effects of low‐level laser therapy (LLLT) on grade I–II ulcers in diabetic foot patients: A meta‐analysis	1
Further psychometric evaluation of the WOUND‐Q: A responsiveness study	1
Healing rates and outcomes following closed transmetatarsal amputations: A systematic review and random effects meta‐analysis of proportions	1
Exploring the role of dermal sheath cells in wound healing and fibrosis	1
Rapid angiogenic hydrogel nanofiber scaffold promotes random flap regeneration and modulates inflammation	1
Comparing mechanical and enzymatic isolation procedures to isolate adipose‐derived stromal vascular fraction: A systematic review	1
Risk factors for venous ulceration in patients with varicose veins of lower extremities	1
CORRIGENDUM	1
Novel insights into negative pressure wound healing from an in situ porcine perspective	1
Progress in copper‐based materials for wound healing	1
Effectiveness of broad‐spectrum antiseptics in production of disinfected maggots of Lucilia sericata for use in wound debridement therapy	1
Retrospective analysis of thermographic imaging in early detection of pressure injuries	1
Issue Information	1
Food and Drug Administration perspective: Advancing product development for non‐healing chronic wounds	1
Image‐based non‐invasive assessment of suction blister wounds for clinical safety and efficacy	1
Evaluation of contraction of the split‐thickness skin graft using three dermal matrices in the treatment of burn contractures: A randomised clinical trial	1
The effect of anatomic location on porcine models of burn injury and wound healing	1
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Chromatin accessibility analysis reveals distinct functions for HDAC and EZH2 activities in early appendage regeneration	1
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Correlation of vascular change with TRPV1, TRPV4, and TRPA1 in a rat model of inferior gluteal artery perforator flap	1
Concise review of non‐invasive physical plasma as a promising treatment option for radiation injuries of the skin	1
Issue Information	1
A Delphi Survey to Develop International Consensus on the Timeframe for Defining a Hospital‐Acquired Pressure Injury (HAPI)	1
Issue Information	1
A systematic review of clinical practice guidelines and other best practice recommendations for pressure injury risk assessment in the United States	1
Sociodemographic predictive factors of increased hospital stay and cost among hospitalised patients with pressure injuries—National Inpatient Sample 2009–2019 (pooled sample)	1
Protection with a collagen wound matrix containing polyhexamethylene biguanide supports innate wound healing in biofilm‐infected porcine wounds	1
Using systems biology approaches to identify signalling pathways activated during chronic wound initiation	1
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2022 Annual Meeting of the Wound Healing Society SAWC‐Spring/WHS Joint Meeting	1
The role of bacterial extracellular vesicles in chronic wound infections: Current knowledge and future challenges	1
Silk proteins in reconstructive surgery: Do they possess an inherent antibacterial activity? A systematic review	1
Photoacoustic monitoring of angiogenesis predicts response to therapy in healing wounds	1
Factors influencing lower extremity amputation outcomes in people with active foot ulceration in regional Australia: A retrospective cohort study	1
Exploring exudate viscosity: A rheological analysis of wound exudates	1
MRSA infection, re‐infection and clinical outcomes in diabetic foot infections	1
The effect of VEGF stimulation in diabetic foot ulcers: A systematic review	1
Efficacy of photobiomodulation therapy on pain, swelling, and trismus following fixation of mandibular fractures	1
Effects of physical activity as an adjunct treatment on healing outcomes and recurrence of venous leg ulcers: A scoping review	1
The pig as a model system for investigating the recruitment and contribution of myofibroblasts in skin healing	1
A novel method to assess photobiomodulation in stimulating regenerative capacity and vascularization in zebrafish	1
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Issue Information	1
Commentary on “The infected diabetic foot: Incidence and risk factors for dehiscence after surgery for diabetic foot infections”	1
Understanding Staphylococcus aureus in hyperglycaemia: A review of virulence factor and metabolic adaptations	1