OOIR: Observatory of International Research

Papers

(The TQCC of Wound Repair and Regeneration is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Donepezil promotes skin flap survival through activation of the HIF‐1α/VEGF signalling pathway	237
Erratum	47
Issue Information	46
A simplified method for monitoring cytokines in wound fluid	36
Interplay between epithelial and mesenchymal cells unveils essential proinflammatory and pro‐resolutive mediators modulated by photobiomodulation therapy at 660 nm	27
The heterogeneous wound microbiome varies with wound care pain, dressing type, and inflammatory gene expression	27
Performance of artificial intelligence chatbots in interpreting clinical images of pressure injuries	25
Cryogel wound dressings based on natural polysaccharides perfectly adhere to irregular wounds for rapid haemostasis and easy disassembly	23
A collagen‐based layered chronic wound biofilm model for testing antimicrobial wound products	23
Patient and wound factors associated with WOUND‐Q scales measuring health‐related quality of life: An international cross‐sectional study	21
Issue Information	20
Fat Graft as Regenerative Treatment of Facial Manifestations of Systemic Sclerosis: A Systematic Review on the Role of Adipose Tissue‐Derived Stem Cells and on Surgical Outcomes to Define a New Standa	20
Current State‐Of‐Play of the EU Advanced Therapy Medicinal Product (ATMP) Field, With an Emphasis on Belgian Human Cell and Tissue Products	20
52^nd Annual Meeting of the Japanese Society for Wound Healing	19
Issue Information	18
Reviewers List	18
Multimodal imaging device to comprehensively assess infection, oxygenation, and wound analytics—A pilot study	18
51^st Annual Meeting of the Japanese Society for Wound Healing	18
Basic haematological tests as inflammatory performance markers of patients treated either by conservative surgery or minor amputation for infected diabetic foot ulcers	17
Letter to editor in response to ‘Tian K, Ye J, Zhong Y, Jia Z, Xu W, Gao S, Cao S, Li K, Wu L. Autologous i‐PRF promotes healing of radiation‐induced skin injury. Wound Repair Regen. 2023;3	17
Research hotspot and trend of chronic wounds: A bibliometric analysis from 2013 to 2022	17
Skin metabolism in obesity: A narrative review	17
Relaxation intervention to improve diabetic foot ulcer healing: Results from a pilot randomized controlled study	16
Gradient expectations: Revisiting Charles Manning Child's theory of metabolic regionalisation in developmental patterning and regeneration	16
Endothelial Cell Responses to Photobiomodulation Treatments in Diabetic Wounds Are Mediated via Concerted PDGF, VEGF and TGF‐β Signalling	16

The effect of quince seed mucilage on perineal pain and healing following episiotomy: A randomised, triple‐blind, placebo‐controlled study	15
A Matrix‐Derived Bioactive Peptide Enhances Epidermal Thickness and Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites	15
Polymicrobial infection in bone biopsies and relapse in diabetic foot osteomyelitis: The role of soft tissue involvement	14
Reconstructed Human Skin Models to Study Superficial and Deep Skin Wound Healing In Vitro	14
Cover Image	13
	13
What is slough? Defining the proteomic and microbial composition of slough and its implications for wound healing	12
53rd Annual Meeting of the Japanese Society for Wound Healing	12
A prospective, randomized, controlled clinical study on the effectiveness of a single‐use negative pressure wound therapy system, compared to traditional negative pressure wound therapy in the treatme	12
	12
Validation and efficacy of ‘pure’ venous lymph node flap in a rat lymphoedema model	12
	12
Digital ulcers associated with scleroderma: A major unmet medical need	11
Effectiveness of Photobiomodulation and Exercise‐Based Rehabilitation on Pain and Functional Recovery in Patients With Rotator Cuff Pathology	11
Outcomes of open reduction and internal fixation of calcaneus fractures: A database study comparing patients with and without diabetes	11
A Macrophage‐Based Cell Therapy Approach Promotes Collagen Deposition in Diabetic Wounds	11
Valsartan nano‐filaments alter mitochondrial energetics and promote faster healing in diabetic rat wounds	11
List of Reviewers	10
A role for vitamin D and the vitamin D receptor in keloid disorder	10
Analgesic Efficacy, Safety and Tolerability of VPX638 Administered Topically to Painful Wounds	10
Therapeutic potential of silkworm sericin in wound healing applications	10
Nanomaterial interventions for wound healing: Current status of preclinical and clinical studies	10
Topical vanadate improves tensile strength and alters collagen organisation of excisional wounds in a mouse model	10
Animal models for the study of acute cutaneous wound healing	10
Keloids in male genitalia—Systematic review and illustrative case report	10
Evaluating the cost‐effectiveness of diabetic foot ulcer management by wound care specialists in Indonesia	10
Investigation of the monocyte/high‐density lipoprotein ratio as a prognostic criterion in burn patients	9
Fibroblast‐Derived TGFβ1 Regulates Skin Repair and Fibrosis	9
Autologous i‐PRF promotes healing of radiation‐induced skin injury	9
	9
Evidence for the in vivo existence and mobilisation of myeloid angiogenic cells and pericyte‐like cells in wound patients after skin grafting	9
Antibiotic‐loaded bone substitutes therapy in the management of the moderate to severe diabetic foot infection: A meta‐analysis	9
A pro‐reparative bioelectronic device for controlled delivery of ions and biomolecules	9
2023 WALT Manipal Abstracts	8
Phenotypic characterisation and associations of leg ulcers in adult sickle cell patients	8
Strengthening the Psychological Care of Patients With Diabetic Foot Complications	8
Issue Information	8
Pressure injuries and biofilms: Microbiome, model systems and therapies	8
Cytokine stability in chronic wound fluid and its association to fibroblast proliferation	7
Pullulan‐Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings	7
	7
Low‐temperature plasma jet suppresses bacterial colonisation and affects wound healing through reactive species	7
Minimising donor‐site morbidity following limbs' injuries with keystone perforator island flap reconstruction	7
	7
Candidate Biomarkers for Hard‐to‐Heal Wounds Revealed by Single‐Cell RNA Sequencing of Wound Fluid in Murine Wound Models	7
3D‐printed electrospun fibres for wound healing	6
Risk factors associated with pressure ulcer recurrence after reconstruction: Analysis of a national database	6
Topical Tranexamic Acid, Adrenaline and Bupivacaine Solution for Pain Management and Healing in Split‐Thickness Skin Graft Donor Sites: An Open‐Label Interventional Study With Randomised Side Allocati	6
Issue Information	6
Healing profiles in patients with a chronic diabetic foot ulcer: An exploratory study with machine learning	6

Clinical utility of⁶⁷Gallium‐SPECT/CTfor determining osteotomy indication in patients with lower‐limb osteomyelitis	6
PI3K/AKT pathway promotes keloid fibroblasts proliferation by enhancing glycolysis under hypoxia	6
Comprehensive analysis of keloid vasculature by tissue clearing and 3D imaging	6
Antimicrobial peptide derived from insulin‐like growth factor‐binding protein 5 improves diabetic wound healing	6
Racial/ethnic disparities in chronic wounds: Perspectives on linking upstream factors to health outcomes	6
Evaluating the impact of an anti‐microbial silver‐impregnated surgical dressing on wound infections and healing: A randomised clinical trial	6
Temporal microbiome changes in axolotl limb regeneration: Stage‐specific restructuring of bacterial and fungal communities with a Flavobacterium bloom during blastema proliferation	6
Issue Information	6
Placenta‐derived mesenchymal stem cells promote diabetic wound healing via exosomal protein interaction networks	6
Comparative transcriptomic adaptations of Staphylococcus aureus to the wound environment in non‐diabetic and diabetic mice	5
Global, Regional, and National Burden of Pressure Ulcers From 1990 to 2021 and Projections Over the Next Decade: Results From the 2021 GBD Study	5
Issue Information	5
Patient Race and Ethnicity Do Not Predict Ulceration Among Ambulatory Patients With Venous Insufficiency	5
Teleconsulting in wound care: Connecting the primary care to the wound specialist reduces unnecessary referrals	5
Issue Information	5
A recombinant signalling‐selective activated protein C that lacks anticoagulant activity is efficacious and safe in cutaneous wound preclinical models	5
	5
The paradigm of stem cell secretome in tissue repair and regeneration: Present and future perspectives	5
Comparison of biopolymer scaffolds for the fabrication of skin substitutes in a porcine wound model	5
Synergistic effects of incorporated additives in multifunctional dressings for chronic wound healing: An updated comprehensive review	5
Commentary on “Polymicrobial Infection in Bone Biopsies and Relapse in Diabetic Foot Osteomyelitis: The Role of Soft Tissue Involvement”	5
Safety and efficacy of treating post‐burn pathological scars with extracorporeal shock wave therapy: A meta‐analysis of randomised controlled trials	5
The effect of high‐voltage monophasic pulsed current on diabetic ulcers and their potential pathophysiologic factors: A systematic review and meta‐analysis	5
Preclinical assessment of novel longer‐duration wear negative pressure wound therapy dressing in a porcine model	5
Outcomes of dermal substitutes in burns and burn scar reconstruction: A systematic review and meta‐analysis	4
Anaerobic bacteria in chronic wounds: Roles in disease, infection and treatment failure	4
Chronic wounds: Treatment consensus	4
Full‐thickness skin columns: A method to reduce healing time and donor site morbidity in deep partial‐thickness burns	4
An overview of systematic reviews of clinical studies of platelet‐rich plasma for venous ulcers	4
The proliferative effects of stem cells from apical papilla‐conditioned medium on rat corneal endothelial cells	4
	4
2024 WHS Abstract Session List Key	4
Severe diabetic foot infections without systemic inflammatory response syndrome: Prospective validation of a new category	4
Evaluation of factors affecting the healing process of venous ulcers: A 12‐week longitudinal study	4
In the face and neck, keloid scar distribution is related to skin thickness and stiffness changes associated with movement	4
Animal experimental models of ischemic wounds – A review of literature	4
Commentary on “Vitabiotic: An Alternative Approach to Diabetic Foot”	4
Update of biomarkers to diagnose diabetic foot osteomyelitis: A meta‐analysis and systematic review	4
Cell‐free therapy based on stem cell‐derived exosomes: A promising approach for wound healing	4
Local problems need global solutions: The metabolic needs of regenerating organisms	4
Issue Information	4
Growth factors for treating chronic venous leg ulcers: A systematic review and meta‐analysis	4
Autologous platelet‐rich fibrin as an adjunct to non‐surgical periodontal therapy—A follow up clinical pilot study	4
Effectiveness of Negative Pressure Wound Therapy With Instillation and Dwell in Removing Nonviable Tissue, Promoting Granulation Tissue, and Reducing Surgical Debridements: A Systematic Literature Rev	4
Global Epidemiology, Burden, and Future Projections of Decubitus Ulcers: A Comprehensive Analysis From 1990 to 2050	4
Role of haematopoietic cell‐specific protein 1‐associated protein X‐1 gene in lipopolysaccharide‐induced apoptosis of human dermal fibroblasts	4
Mönckeberg's medial calcific sclerosis in diabetic and non‐diabetic foot infections	4
The impact of youth‐onset type 2 diabetes on postoperative wound healing complications	4
	4
Porcine‐derived collagen peptides promote re‐epithelialisation through activation of integrin signalling	4