OOIR: Observatory of International Research

Papers

(The median citation count of Free Radical Research is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Down-regulation of Selenoprotein K impairs the proliferation and differentiation of chicken skeletal muscle satellite cells by inhibiting the Nrf2 antioxidant signaling pathway	96
Three-dimensional electron paramagnetic resonance imaging of mice using ascorbic acid sensitive nitroxide imaging probes	48
The relationship between serum superoxide dismutase and thyroid function in obese patients after Laparoscopic sleeve gastrectomy	48
Assessment of antioxidant and antiparkinsonian potential of a new diterpene isolated from Croton argyrophylloides	45
Thermodynamic and kinetic studies on antioxidant capacity of amentoflavone: a DFT (density functional theory) computational approach	31
The Val16Ala MnSOD gene polymorphism is associated with hypertension in self-declared black individuals	29
Molecular dissection of anti-colon cancer activity of NARI-29: special focus on H₂O₂ modulated NF-κB and death receptor signaling	29
Hydroxyl radical scavenging and chemical repair capabilities of positively charged peptides (PCPs): a pulse radiolysis study	24
Unveiling an oxidative stress-linked diagnostic signature and molecular subtypes in preeclampsia: novel insights into pathogenesis	20
Inhibition of glutamine metabolism increases sensitivity to plasma-activated medium-induced cytotoxicity	18
Brca2 ^{(p.T1942fs/+)} dissipates ovarian reserve in rats through oxidative stress in follicular granulosa cells	17
Biocompatibility assessment of bovine serum albumin conjugated manganese dioxide nanoparticle and their therapeutic role against microwave radiation induced haematological toxicity in male Wistar rats	17
Bis(1-methylimidazol-2-yl) diselenide and its evaluation as a chemical radio-protector: role of kinetic rate constants for ROS scavenging and glutathione peroxidase like activity	17
In vitro analysis of catalase and superoxide dismutase mimetic properties of blue tattoo ink	16
Reduction of oxidative damage in prostate tissue caused by radiation and/or chloroquine by apocynin	15
Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy	15
Effects of LET on oxygen-dependent and-independent generation of hydrogen peroxide in water irradiated by carbon-ion beams	14
Current understanding of plasma-activated solutions for potential cancer therapy	14
Urban aerosol particulate matter promotes cellular senescence through mitochondrial ROS-mediated Akt/Nrf2 downregulation in human retinal pigment epithelial cells	13
Hypoxia induces proliferation via NOX4-Mediated oxidative stress and TGF-β3 signaling in uterine leiomyoma cells	12
Circadian rhythm and time-of-day-effects of (anti)oxidant biomarkers for epidemiological studies	12
Ferritin with methylglyoxal produces reactive oxygen species but remains functional	12
The mitochondrial antioxidant SS-31 attenuated lipopolysaccharide-induced apoptosis and pyroptosis of nucleus pulposus cells via scavenging mitochondrial ROS and maintaining the stability of mitochond	12
Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials	12
MicroRNA-328-3p facilitates the progression of gastric cancer via KEAP1/NRF2 axis	11

Oxidative damage in the liver and brain of the rats exposed to frequency-dependent radiofrequency electromagnetic exposure: biochemical and histopathological evidence	11
Chemistry of the carboxylic acid of dihydrofluorescein in oxidation and its application to fluorogenic ROS sensing	10
Upregulation of p67^phox in response to ischemia/reperfusion is cardioprotective by increasing ZIP2 expression via STAT3	10
Generation and measurement of low-temperature plasma for cancer therapy: a historical review	10
Comparison of three methods for in vivo quantification of glutathione in tissues of hypertensive rats	10
Redox system and ROS-related disorders in peroxisomes	9
In-gel SOD assay reveals SOD-2 is the single active, water-soluble SOD enzyme in C. elegans	9
Ginsenoside Re protects against kainate-induced neurotoxicity in mice by attenuating mitochondrial dysfunction through activation of the signal transducers and activators of transcription 3 signaling	9
Superoxide dismutase and glutathione peroxidase activities in a population exposed to high indoor radon concentration: a preliminary report	9
Autoxidation of ascorbate mediates lysine N-pyrrolation	9
Untargeted metabonomic analysis of non-alcoholic fatty liver disease with iron overload in rats via UPLC/MS	8
Growth acceleration of Nile tilapia at 21 to 31 weeks of age with plasma-treated air-supplied water	8
The radical scavenger capacity and mechanism of prenylated coumestan-type compounds: a DFT analysis	8
Plasma activated Ringer’s lactate solution	8
Hydrogen peroxide activates APE1/Ref-1 via NF-κB and Parkin: a role in liver cancer resistance to oxidative stress	8
Role of oxidative stress in induction of trans-differentiation of neutrophils in patients with rheumatoid arthritis	7
Cutting-edge insights into Helicobacter research	7
Andrographolide attenuates sepsis-induced acute kidney injury by inhibiting ferroptosis through the Nrf2/FSP1 pathway	7
Exploring the Oxidative Mechanism of Methotrexate on Catalase Enzyme: An In Vitro Study	7
VDR promotes nucleus pulposus cell mitophagy as a protective mechanism against oxidative stress injury	7
Rhabdomyolysis aggravates renal iron accumulation and acute kidney injury in a humanized mouse model of sickle cell disease	7
Arachidonic acid: reconciling the dichotomy of its oxidative cascade through specific deuteration	7
Superoxide-producing associates from gastrointestinal bacteria: stimulation of its growth by exogenous superoxide-producing complex from raspberries	7
Antioxidant activity of caffeic acid: thermodynamic and kinetic aspects on the oxidative degradation pathway	7
Epoxides: an underestimated lipid oxidation product	7
Redox remodeling of central metabolism as a driving force for cellular protection, proliferation, differentiation, and dysfunction	7
Tetrahydrocurcumin exhibits neuroprotective effects by inhibiting neuron ferroptosis via activity of iPLA2β/p38 MAPK phosphorylation in rat TBI model	7
Melatonin alleviates hydrogen peroxide induced oxidative damage in MC3T3-E1 cells and promotes osteogenesis by activating SIRT1	7
Metformin ameliorates gestational diabetes mellitus via inhibiting ferroptosis of trophoblasts through the Nrf2/HO-1 signaling pathway	6
DhHP-6 alleviates inflammation and reduces vascular permeability by eliminating reactive oxygen species	6
Ameliorative effect of salidroside on the cyclophosphamide-induced premature ovarian failure in a rat model	6
Formation of free radicals in Chi-aroma Baijiu during aging process with fat pork	6
Gold nanoparticles-supported iron oxide particles endows bone scaffolds with anti-tumor function	6
Correction	5
Correction	5
Implication of mitochondrial ROS-NLRP3 inflammasome axis during two-hit mediated acute lung injury in mice	5
Mechanistic insight into the free radical scavenging and xanthine oxidase (XO) inhibitor potent of monoacetylphloroglucinols (MAPGs)	5
Hypoxia induces dichotomous and reversible attenuation of T cell responses through reactive oxygen species-dependent phenotype redistribution and delay in lymphoblast proliferation	5
Lipid composition dictates the rate of lipid peroxidation in artificial lipid droplets	5
Protective effects of krill oil on high fat diet-induced cognitive impairment by regulation of oxidative stress	4
Exploring the impact of Apelin and Reactive Oxygen Species on autophagy and cell senescence in pre-eclampsia	4
Prevention of ferroptosis in acute scenarios: an in vitro study with classic and novel anti-ferroptotic compounds	4
Changes in tumor suppressors and inflammatory responses during hydrogen peroxide-induced senescence in rat fibroblasts	4
Reactive oxygen species: the root cause of nanoparticle-induced toxicity in Drosophila melanogaster	4
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury	4
Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress	4
Modulation of reactive oxygen species in cancers: recent advances	4
Non-thermal plasma elicits ferrous chloride-catalyzed DMPO-OH	4
Adsorption of free radical TEMPO onto Al₂O₃ nanoparticles and evaluation of radical scavenging activity	4
Modulation of inflammatory signaling by vitamin E metabolites and its therapeutic implications	4

Identification of narciclasine as a novel NRF2 inhibitor	4
A new mitochondrial probe combining pyrene and a triphenylphosphonium salt for cellular oxygen and free radical detection via fluorescence lifetime measurements	4
Relationship between toxicity and oxidative stress of the nanoencapsulated colchicine in a model of Drosophila melanogaster	4
Potential role of free-radical processes in biomolecules damage during COVID-19 and ways of their regulation	4
Anti-oxidants as therapeutic agents for oxidative stress associated pathologies: future challenges and opportunities	4
Increased production of 8-oxo-7,8-dihydroguanine in human urine, a novel biomarker of osteoporosis	4
Statement of Retraction: ‘Up regulation of IL-6 by ischemic preconditioning in normal and fatty rat livers: Association with reduction of oxidative stress	4
SIRT2 tyrosine nitration by peroxynitrite in response to renal ischemia/reperfusion injury	4
Efficacy of periodic cold plasma treatment in a paddy to produce white-core grains in brewer’s rice cultivar Yamadanishiki	4
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway	4
Antioxidant action of persulfides and polysulfides against free radical-mediated lipid peroxidation	3
Astaxanthin protects human ARPE-19 retinal pigment epithelium cells from blue light-induced phototoxicity by scavenging singlet oxygen	3
Chemical and biological basis for development of novel radioprotective drugs for cancer therapy	3
Hyperoxia induces autophagy in pulmonary epithelial cells: insights from in vivo and in vitro experiments	3
Association of poly(rC)-binding protein-2 with sideroflexin-3 through TOM20 as an iron entry pathway to mitochondria	3
Catechol-derived Mannich bases: radical regulatory properties, cytotoxicity and interaction with biomolecules	3
Ferroptosis: a new target for hepatic ischemia-reperfusion injury?	3
Serum and cecal metabolic profile of the insulin resistant and dyslipidemic p47^phoxknockout mice	3
Melittin induces ferroptosis and ER stress-CHOP-mediated apoptosis in A549 cells	3
FeTMPyP a peroxynitrite decomposition catalyst ameliorated functional and behavioral deficits in chronic constriction injury induced neuropathic pain in rats	3
Relationship between hemodynamic alteration and sympathetic nerve activation following a single oral dose of cinnamtannin A2	3
Decreased plasma H₂O₂ levels are associated with the pathogenesis leading to COVID-19 worsening and mortality	3
Ferulic acid protects renal tubular epithelial cells against anoxia/reoxygenation injury mediated by AMPKα1	3
Trafficking of oxidative stress-generated lipid hydroperoxides: pathophysiological implications	3
Modified quantum mechanical approach for the estimation of single-electron reduction potential of nitroaromatic compounds in aqueous medium	3
The downregulation of NADPH oxidase Nox4 during hypoxia in hemangioendothelioma cells: a possible role of p22^phox on Nox4 protein stability	3
Constitutive oxidants from hepatocytes of male iPLA2β-null mice increases the externalization of phosphatidylethanolamine on plasma membrane	3
A novel approach to the analysis of spin-trapped free radicals using dimethyl sulfoxide and gas chromatography – mass spectrometry (GC-MS) with both solvent extraction and headspace solid phase microe	3
Cancer-specific cytotoxicity of Ringer’s acetate solution irradiated by cold atmospheric pressure plasma	3
The impact of aerobic exercise timing on BMAL1 protein expression and antioxidant responses in skeletal muscle of mice	2
Continuously increased generation of ROS in human plasma after cardiac arrest as determined by Amplex Red oxidation	2
Theoretical studies on the antioxidant activity of potential marine xanthones	2
Febuxostat reduces muscle wasting in tumor-bearing mice with LM8 osteosarcoma cells via inhibition of reactive oxygen species generation	2
Enhancing effect of the coexisting alpha-tocopherol on quercetin absorption and metabolism	2
Modifications of DJ-1 in which pI shifts to acidic in red blood cells a potential biomarker for Parkinson’s disease at early stages	2
Extracellularly secreted cysteine derived from cystine regulates oxidative and electrophilic stress in HepG2 cells	2
NRF2 signaling and amino acid metabolism in cancer	2
MicroRNA-1287-5p promotes ferroptosis of osteosarcoma cells through inhibiting GPX4	2
Redox interactions of immune cells and muscle in the regulation of exercise-induced pain and analgesia: implications on the modulation of muscle nociceptor sensory neurons	2
Molecular targets for anti-oxidative protection of açaí berry against diabetes myocardial ischemia/reperfusion injury	2
Defense systems to avoid ferroptosis caused by lipid peroxidation-mediated membrane damage	2
Upregulation of microRNA-34a enhances myocardial ischemia-reperfusion injury via the mitochondrial apoptotic pathway	2
Formation of radicals in irradiated maltose – the role of hydrogen bonding with water	2
Edaravone inhibits neuronal ferroptosis and alleviates acute Central nervous system injury induced by diquat via enhancement of METTL14-mediated m6A methylation of Aldh1	1
New era of plasma dentistry	1
Metabolomics analysis of the effects of quercetin on Cd-induced hepatotoxicityin rats	1
Role and management of oxidative stress in human disease	1
Elevated oxidative stress in patients with congenital heart disease and the effect of cyanosis: a meta-analysis	1
Enhanced anticancer activity of (–)-epigallocatechin-3-gallate (EGCG) encapsulated NPs toward colon cancer cell lines	1
Correction	1
Combined action of FOXO1 and superoxide dismutase 3 promotes MDA-MB-231 cell migration	1
In memoriam: Emeritus Professor Robin L. Willson	1
Redox factors in the antioxidant activity of nitroxides toward DNA guanyl and 2-deoxyribose-peroxyl radicals	1
Nitric oxide is an irreversible human diamine oxidase inhibitor	1
The impact of hyperbaric oxygen therapy on the redox balance of patients with diabetic foot syndrome	1
Karyoptosis as a novel type of UVB-induced regulated cell death	1
MiR-125b-5p is targeted by curcumin to regulate the cellular antioxidant capacity	1
FOXO signaling pathway participates in oxidative stress-induced histone deacetylation	1
EP4 receptor agonist CAY10598 upregulates ROS-dependent Hsp90 cleavage in colorectal cancer cells	1
Ascorbic acid induces ferroptosis via STAT3/GPX4 signaling in oropharyngeal cancer	1
Oxidative stress and gender disparity in cancer	1
Uranium induces kidney cells pyroptosis in culture involved in ROS/NLRP3/caspase-1 signaling	1
Examining the prognostic and clinicopathological significance of GPX4 in human cancers: a meta-analysis	1
The role of miR-199b-3p in regulating Nrf2 pathway by dihydromyricetin to alleviate septic acute kidney injury	1
Indole-3-carbinol loaded-nanocapsules modulated inflammatory and oxidative damages and increase skin wound healing in rats	1
Retrograde response to mitochondrial dysfunctions associated to LOF variations in FLAD1 exon 2: unraveling the importance of RFVT2	1
Low-temperature plasma as a strategy to achieve SDGs	1
The role of oxidative stress and inflammation biomarkers in pre- and postoperative monitoring of prostate cancer patients	1
The effect of low-level laser therapy on the oxidative stress level and quality of life in patients with Hashimoto’s thyroiditis	1
Distribution and quantitative analysis of homoanserine and its 2-oxo derivative in mouse tissues	1