OOIR: Observatory of International Research

Papers

(The TQCC of Free Radical Research is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Autoxidation of ascorbate mediates lysine N-pyrrolation	52
Untargeted metabonomic analysis of non-alcoholic fatty liver disease with iron overload in rats via UPLC/MS	49
Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy	48
Rhabdomyolysis aggravates renal iron accumulation and acute kidney injury in a humanized mouse model of sickle cell disease	43
Urban aerosol particulate matter promotes cellular senescence through mitochondrial ROS-mediated Akt/Nrf2 downregulation in human retinal pigment epithelial cells	29
In-gel SOD assay reveals SOD-2 is the single active, water-soluble SOD enzyme in C. elegans	25
Down-regulation of Selenoprotein K impairs the proliferation and differentiation of chicken skeletal muscle satellite cells by inhibiting the Nrf2 antioxidant signaling pathway	24
Effects of LET on oxygen-dependent and-independent generation of hydrogen peroxide in water irradiated by carbon-ion beams	20
Unveiling an oxidative stress-linked diagnostic signature and molecular subtypes in preeclampsia: novel insights into pathogenesis	19
MicroRNA-328-3p facilitates the progression of gastric cancer via KEAP1/NRF2 axis	19
Andrographolide attenuates sepsis-induced acute kidney injury by inhibiting ferroptosis through the Nrf2/FSP1 pathway	18
Reduction of oxidative damage in prostate tissue caused by radiation and/or chloroquine by apocynin	18
Chemical and biological basis for development of novel radioprotective drugs for cancer therapy	17
Urinary 8-oxo-7,8-dihydroguanosine as a potential biomarker for the prognosis of acute poisoning patients in the emergency Intensive-care unit: a prospective observational study	17
Prevention of ferroptosis in acute scenarios: an in vitro study with classic and novel anti-ferroptotic compounds	16
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury	16
Melittin induces ferroptosis and ER stress-CHOP-mediated apoptosis in A549 cells	15
Cancer-specific cytotoxicity of Ringer’s acetate solution irradiated by cold atmospheric pressure plasma	14
Molecular targets for anti-oxidative protection of açaí berry against diabetes myocardial ischemia/reperfusion injury	14
Ferulic acid protects renal tubular epithelial cells against anoxia/reoxygenation injury mediated by AMPKα1	14
The role of miR-199b-3p in regulating Nrf2 pathway by dihydromyricetin to alleviate septic acute kidney injury	14
Graphene oxide nanoflakes prevent reperfusion injury of Langendorff isolated rat heart providing antioxidative activity in situ	13
Involvement of iron ions in 6-hydroxydopamine-induced disruption of intracellular copper metabolism	13
Modifications of DJ-1 in which pI shifts to acidic in red blood cells a potential biomarker for Parkinson’s disease at early stages	13
Role and management of oxidative stress in human disease	12

NADPH oxidase derived ROS promote arterial contraction in early postnatal rats by activation of L-type voltage-gated Ca ²⁺ channels	12
Hydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway	12
Distal substituents effect of 4-oxo-TEMPO derivatives bearing a benzyl group at the 2-position on the reduction resistance toward ascorbate	12
Involvement of hydrogen peroxide in sonodynamical effect with sinoporphyrin sodium in hypoxic situation	12
Effect of the nature of the chelated metal on the photodynamic activity of metalloporphyrins	11
Oxidative imbalance linked to impaired mitochondrial bioenergetics mediates the toxicity of mesoionic compounds MI-D and MI-J in hepatocarcinoma cells (HepG2)	10
SARS-CoV-2 induces mitochondrial dysfunction and cell death by oxidative stress/inflammation in leukocytes of COVID-19 patients	10
The microbiota catabolites of quercetin glycosides concertedly enhance the resistance against acetaldehyde-induced oxidative stress	10
Effects of lysosomal low-density lipoprotein oxidation by ferritin on macrophage function	10
Betulinic acid mitigates oxidative stress-mediated apoptosis and enhances longevity in the yeast Saccharomyces cerevisiae model	10
Low density lipoprotein oxidized under lysosomal conditions decreases arterial vasodilatation	9
Apelin deficiency exacerbates cardiac injury following infarction by accelerating cardiomyocyte ferroptosis	9
Carbonylation induced by antibiotic and pesticide residues on casein increases its IgE binding and allergenicity	9
Association of circulatory PCSK-9 with biomarkers of redox imbalance and inflammatory cascades in the prognosis of diabetes and associated complications: a pilot study in the Indian population	9
Metformin suppresses metabolic dysfunction-associated fatty liver disease by ferroptosis and apoptosis via activation of oxidative stress	9
Beneficial effects of vitamin B ₁₂ treatment in pediatric patients diagnosed with vitamin B ₁₂ deficiency regarding total-native t	9
Hyper-energy metabolism of oxidative phosphorylation and enhanced glycolysis contributes to radioresistance in glioma cells	8
Growth acceleration of Nile tilapia at 21 to 31 weeks of age with plasma-treated air-supplied water	8
Dissecting the potential role of ferroptosis in liver diseases: an updated review	8
The Val16Ala MnSOD gene polymorphism is associated with hypertension in self-declared black individuals	8
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway	7
Modulation of inflammatory signaling by vitamin E metabolites and its therapeutic implications	7
Thermodynamic and kinetic studies on antioxidant capacity of amentoflavone: a DFT (density functional theory) computational approach	7
Circadian rhythm and time-of-day-effects of (anti)oxidant biomarkers for epidemiological studies	7
Antioxidant action of persulfides and polysulfides against free radical-mediated lipid peroxidation	7
The mitochondrial antioxidant SS-31 attenuated lipopolysaccharide-induced apoptosis and pyroptosis of nucleus pulposus cells via scavenging mitochondrial ROS and maintaining the stability of mitochond	7
Assessment of antioxidant and antiparkinsonian potential of a new diterpene isolated from Croton argyrophylloides	7
Superoxide dismutase and glutathione peroxidase activities in a population exposed to high indoor radon concentration: a preliminary report	7
Serum and cecal metabolic profile of the insulin resistant and dyslipidemic p47^phoxknockout mice	7
Epoxides: an underestimated lipid oxidation product	7
In vitro analysis of catalase and superoxide dismutase mimetic properties of blue tattoo ink	7
Potential role of free-radical processes in biomolecules damage during COVID-19 and ways of their regulation	6
Formation of free radicals in Chi-aroma Baijiu during aging process with fat pork	6
Relationship between toxicity and oxidative stress of the nanoencapsulated colchicine in a model of Drosophila melanogaster	6
Changes in tumor suppressors and inflammatory responses during hydrogen peroxide-induced senescence in rat fibroblasts	6
Decreased plasma H₂O₂ levels are associated with the pathogenesis leading to COVID-19 worsening and mortality	6