OOIR: Observatory of International Research

Papers

(The TQCC of American Journal of Respiratory and Critical Care Medicine is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Very Late Antigen-4: A Novel Receptor for Club Cell Secretory Protein 16 to Control Inflammation	1461
Rare Case of Isolated Systemic Arterial Supply to Upper Lobe of Left Lung	326
Electromagnetic Navigation Bronchoscopy and Transthoracic Sampling of Peripheral Pulmonary Nodules: One Step Back, One Leap Forward for the Evaluation of Technology Targeting the Lung Periphery	295
Waxing and Waning Cysts and Nodules	257
Dyspnea in the ICU: It Is Difficult to See What Patients Feel	254
Retraction: Altered Antibiotic Pharmacokinetics during Extracorporeal Membrane Oxygenation: Cause for Renal Function?	238
Be the Change: Advancing Lung Health and Closing the Global Healthcare Gap	226
The Exposome Applied: A Step toward Defining the Totality of Environmental Exposures in Asthma	224
Is Reverse Triggering in Pressure-Support Ventilation an Oxymoron? Maybe Not!	190
Is Achieving a Fully Race-Neutral Approach to Lung Function Classification Even Possible?	189
Timing of Noninvasive Ventilation Initiation for Chronic Hypercapnic Respiratory Failure of Chronic Obstructive Pulmonary Disease	178
Atorvastatin in Severity-Stratified Pulmonary Sarcoidosis: A Phase II Randomized Controlled Trial	173
Location of Care Delivery for Pulmonary Arterial Hypertension in the United States	167
Reply to Hatipoğlu et al., Wijkstra et al., and Crimi and Carlucci	157
Differences in Patient Outcomes across the Pulmonary Fibrosis Foundation Care Center Network	157
Asthma and COVID-19: Preconceptions about Predisposition	150
Beyond Septic Shock: Who Else Requires Immediate Antibiotics?	147
Airway Androgen Receptor Expression: Regulator of Sex Differences in Asthma?	145
Pulmonary Hypertension Care Delivery in the U.S.: Is It Time to Get with the Guidelines?	135
Select Airway Specialized Pro-Resolving Mediators Are Associated with Recovery from Non-Viral COPD Exacerbations	134
Reply to Jha: Understanding the Pathophysiological and Clinical Changes in Lung Injury Models	133
Large Vessel Vasculitis in a Young Woman with EIF2AK4-associated Pulmonary Capillary Hemangiomatosis/Pulmonary Veno-Occlusive Disease	131
Reply to Jimenez and Hyzy and to Le Stang and Dres	128
The Many Roles of Cholesterol in Sepsis: A Review	127
DNA Methylome Alterations Are Associated with Airway Macrophage Differentiation and Phenotype during Lung Fibrosis	123

Bronchoscopic Lung Volume Reduction: To the Heart of the Matter	122
The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality	122
Genetically Identifying the “Thromboembolic” in Chronic Thromboembolic Pulmonary Hypertension	119
Specific Respiratory System Compliance in COVID-19 and Non–COVID-19 Acute Respiratory Distress Syndrome	113
August 15 Highlight	113
Reply to He et al.	111
Concerning the Growth Failure during Lung Function Development: Beyond the Evaluation	110
Reply to Jha	107
Identification of Large Airway Collapse with Symptoms Using Dynamic Chest Radiography	107
April 15 Highlight	107
Remodeling Phenotypes Take Center Stage in the Prediction of Preschool Wheeze Attacks	105
Enhanced Postbronchoscopic Lung Volume Reduction Pneumothorax Detection with Digital Tomosynthesis	100
2022-2023 Journal Award Winners	98
Equitably Allocating Resources during Crises: Racial Differences in Mortality Prediction Models	96
Prognosis of Patients with Chronic Obstructive Pulmonary Disease Not Eligible for Major Clinical Trials	94
Prime Time for Proteomics in Pulmonary Arterial Hypertension Risk Assessment?	94
Research Needs for Inpatient Management of Severe Alcohol Withdrawal Syndrome: An Official American Thoracic Society Research Statement	92
Right Atrial Angiosarcoma with Embolic Lung Metastases Masquerading as Atypical Pneumonitis	91
Extracellular Vesicles as Therapy for Congenital Diaphragmatic Hernia–associated Pulmonary Hypoplasia: Extra! Extra! Read All About Autophagy!	89
Lessons from the North: CanCOLD, Exercise, and Chronic Obstructive Pulmonary Disease	87
Retraction: Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques	86
No One Left Behind: Access to Prevention and Treatment for All: Message on World Lung Day from M. Patricia Rivera, M.D. President of the American Thoracic Society	86
Endovascular Forceps Biopsy of Pulmonary Artery Intimal Sarcoma: A Safer Approach	84
Reply to Chung et al. and to Rogliani and Calzetta	84
Reply to Santos et al.: Open Up the Lung and Keep the Lung Vessels Open	84
Stop the Asthma Treatment Elevator, We Need to Get Off!	83
Nasal High Flow to Modulate Dyspnea in Orally Intubated Weanable Patients	82
COPD Detection: Hurdles and Struggles	81
Maldevelopment of the Immature Pulmonary Vasculature and Prolonged Patency of the Ductus Arteriosus: Association or Cause?	80
Disconcerting and Counterintuitive Findings from a Trial of Exercise in Cystic Fibrosis: Can Exercise Make Our Patients Worse?	80
Long-Term Doxycycline Therapy for Stable Chronic Obstructive Pulmonary Disease: Do the Benefits Outweigh the Drawbacks?	80
Population Prevalence of Hypercapnic Respiratory Failure from Any Cause	80
Reply to Tiruvoipati et al.: VENT-AVOID Trial: Avoiding Acute Hypercapnic Respiratory Failure!	79
Systemic Air Embolism and Mediastinal Emphysema after Pneumonia	76
Stress Is in the Air: Ambient Reactive Oxygen Species and COVID-19	76
Lung Function as a Biomarker of Health: An Old Concept Rediscovered	76
Cleaving the Acute Respiratory Distress Syndrome into Treatable Traits: A Role for Caspase 1?	76
Pneumothorax: Challenging the Paradigm of Persistent Air Leak, but Where Is the Leak?	75
Low-Dose Anticoagulation to Prevent Intracranial Hemorrhage in COVID-19 Patients under Extracorporeal Membrane Oxygenation Support	75
Reply to Wendel-Garcia et al.: Low-Dose Anticoagulation to Prevent Intracranial Hemorrhage in COVID-19 Patients under Extracorporeal Membrane Oxygenation Support	75
Development of a Mask for Bronchoscopy to Prevent Infection during the COVID-19 Pandemic: Image Evaluation	74
The Long-Term Respiratory Perils of War	74
Scrutinizing the Mechanisms of West Non–Zone 3 Conditions during Tidal Ventilation	72
Dynamic Metabolic Risk Profiling of World Trade Center Lung Disease: A Longitudinal Cohort Study	71
A Further Step Toward Meaningful Trial Outcomes for Patients with Pulmonary Arterial Hypertension: Minimal Important Difference in 6-minute-walk Distance	71
Individualized Treatment Duration in Tuberculosis Treatment: Precision versus Simplicity	70
Managing Your Asthma: Avoiding Irritants	70
Pulmonary Hypertension Caused by Interstitial Lung Disease: A New iNK(T)ling into Disease Pathobiology	68
Treatment of Hypersensitivity Pneumonitis (HP)	68
Interpreting the Deep Sulcus Sign	67

Can Pulse Rate Responses Be a Metric of Cardiovascular Outcome in Patients with Obstructive Sleep Apnea?	66
Update in Pediatrics 2020	66
Mechanisms of Obesity-related Asthma: Is Insulin Getting on Your Nerves?	65
Relevant Factors for Physical, Mental, and Cognitive Problems in ICU Survivors	65
Lung Cancer Risk and Delivering on the Promise of the Genomic Era	65
Tracheal Y-Stent–induced Carinal Reunion after Complicated Aerodigestive Fistula	64
Double Trouble: Airflow and Pulmonary Vascular Obstruction	64
Can Breathing Poor-quality Air Lead to Poor-quality Sleep in Children?	64
Reply to: Sookaromdee and Wiwanitkit	64
March 1 Highlight	63
Triple-Therapy Trials for Chronic Obstructive Pulmonary Disease: Methodological Considerations in the Mortality Effect	62
Use of Computed Tomography Lung Densitometry as an Outcome Measure for Emphysema Progression: The Case of Losartan	62
Rasmussen Aneurysm: A Forgotten Complication	62
Olfactory Nasal Nitric Oxide Link in COVID-19: A Marker of Neurogenesis or Risk Factor for Chronic Rhinosinusitis?	62
Pulmonary Involvement in Sweet’s Syndrome	61
Good’s Syndrome: Thymoma with Acquired Immunodeficiency	60
Informing Healthcare Decisions with Observational Research Assessing Causal Effect: An American Thoracic Society Statement Not Ready for Implementation	59
Epirubicin and Cyclophosphamide–induced Acute Fibrinous and Organizing Pneumonia	59
Thiamine for Septic Shock: Take Your Vitamins?	59
Tuberculosis Diagnoses Following Wildfire Smoke Exposure in California	59
Outdoor Air Pollution and Your Health	58
A Novel Computed Tomography Score Reveals More about Air Trapping in Asthma	58
Reply to: Huang et al.	57
The Effectiveness of Prophylactic Use of High-Flow Nasal Cannula Oxygen Therapy and Noninvasive Positive Pressure Ventilation on Reintubation: Concerning the Heterogeneity of Patients with Acute Brain	57
High-Dose Inhaled Nitric Oxide in Acute Hypoxemic Respiratory Failure: Need for Patient Phenotyping?	57
Tacrolimus and the Treatment of Pulmonary Fibrosis	57
Lung Cryobiopsy Versus Surgical Lung Biopsy for Diagnosing Fibrotic Interstitial Lung Disease: Still Looking for the “Perfect” Trial	56
Larger Mediastinal Lymph Nodes Are Associated with Worse Lung Function in Persistent Asthma	56
“KEAP”ing Alveolar Macrophage Mitochondria Content in Chronic Obstructive Pulmonary Disease	56
Use of CAPTURE to Identify Individuals Who May or May Not Require Treatment for Chronic Obstructive Pulmonary Disease	56
Research Accomplishments in Pulmonary, Critical Care, and Sleep: A Retrospective Review	55
Inhaled NO in COVID-19 Acute Respiratory Distress Syndrome: Yes or No?	55
Use FEV₁/FVC Z-Score Staging to Minimize Sex and Age Bias in Staging Chronic Obstructive Pulmonary Disease	55
Uncontrollable Hemoptysis owing to Pseudoangiosarcomatous Carcinoma of the Lung	54
Persistent Lymphocytopenia Does Not Increase Nosocomial Infection Risk in the ICU	54
Cystic Fibrosis: From Tragedy to Triumph	54
Surrogate Markers for Pulmonary Hypertension May Inform Prognosis in Lung Cancer	54
Addressing the Use of the CAPTURE (a Chronic Obstructive Pulmonary Disease Screening Tool) in Chronic Obstructive Pulmonary Disease Treatment Decisions	54
The Ongoing Quest for Predictive Biomarkers in Chronic Obstructive Pulmonary Disease	53
Opioids for Sedation: Has the Pendulum Swung Too Far?	53
Definitions of Dysbiosis in Chronic Lung Allograft Dysfunction and High Bacterial Biomass	53
The Yin and Yang of the Renin–Angiotensin–Aldosterone System in Acute Kidney Injury	53
October 1 Highlight	53
An Alarmin Role for P2Y₁₃ Receptor during Viral-driven Asthma Exacerbations	52
List of Reviewers—2021	52
Erratum: Selective Modulation of the Pulmonary Innate Immune Response Does Not Change Lung Microbiota in Healthy Mice	52
Sudden Breathlessness	51
Bronchial Atresia and Bronchogenic Cyst with Saprophytic Aspergilloma	51
Cell Therapy with the Cell or without the Cell for Premature Infants?: Time Will Tell	51
Electrical Impedance Tomography to Evaluate Sigh Effects in Unilateral Lung Injury	51
Endobronchial Clear-Cell Sugar Tumor	50
Reply to Zheng et al.	50
Reply to Jin et al.: Inhaled Treprostinil after Initial Clinical Worsening: To Continue or Not to Continue, That’s the Question	49
Reply to Florio et al.: A Physiological Hypothesis to Support the Use of Continuous Positive Airway Pressure at Extubation among Patients with Obesity	49
PAP Therapy–Quick Tips for Troubleshooting to Address Problems with Use	49
Unusual Pneumothorax with Cardiac Perforation by Bone Cement after Percutaneous Vertebroplasty	49
Reduced Aerobic Exercise Capacity in Adults Born at Very Low Birth Weight: No Small Matter!	49
Bronchial Mucosal Microcirculation in SARS-CoV-2 Infection: Role in Innate Humoral Defense?	49
NOTCH-ing up Surface Tension in the Fibrotic Lung	48
Reviewers—2022	48
Can Intermittent Hypoxemia Help Detect Pulmonary Hypertension in High-risk Preemies?	48
Reply to Donovan and Patel	48
Time to Tailor the One-Size-Fits-All Approach?	48
Better to Be an Agnostic than a Believer (at Least in Pulmonary Fibrosis)	48
Evaluation of Droplet Countermeasures by a Particle Visualization System in Simulated Bronchoscopy	47
A Proposed Revision of the Stepwise Treatment Algorithm in Asthma	47
Update in Sleep 2021	47
Enhancing Our Understanding of Breathing Mechanics in Nonintubated Patients with Acute Hypoxemic Respiratory Failure	47
Reply to Jain: Olfactory Nitric Oxide Link in COVID-19: A Marker of Neurogenesis or Risk Factor for Chronic Rhinosinusitis?	47
COVID-19–related Acute Respiratory Distress Syndrome Subphenotypes and Differential Response to Corticosteroids: Time for More Precision?	47
Revisiting Old Friends: Adjunctive Therapies in Acute Respiratory Distress Syndrome	46
Reply to Camporota et al.: The 4DPRR Index and Mechanical Power: A Step Ahead or 4 Steps Backward?	46
Air Pollution and Bronchitis: Childhood Exposure, Lifelong Consequences	46
In Case of Invasive Nodule, Break Ground Glass	46
High- versus Low-Flow Extracorporeal Respiratory Support in Experimental Hypoxemic Acute Lung Injury	46
Nanoplastics in the Human Respiratory System	46
November 1 Highlight	46
Individualized Treatment Effects: Machine Learning Can Revolutionize Observations, but Let’s Understand What We Are Observing	45
Moving Beyond Antibiotics: Exploring the Potential of an Antivirulence Monoclonal Antibody against Pseudomonas aeruginosa in Bronchiectasis	45
Reply to: Intervening on Social Determinants for Better Outcomes in Pediatric Tuberculosis Management	45

Reply to Wang et al.	45
Aspirating Pneumothorax: Clearing the Air or Muddying the Water?	45
The 4DPRR Index and Mechanical Power: A Step Ahead or Four Steps Backward?	45
Crossing Kingdoms: Host–Microbial Endotyping and the Quest to Understand Treatable Traits in Chronic Obstructive Pulmonary Disease	45
Extracorporeal Membrane Oxygenation instead of Invasive Mechanical Ventilation in a Patient with Severe COVID-19–associated Acute Respiratory Distress Syndrome	44
CFTR Modulators to the Rescue of Individuals with Cystic Fibrosis and Advanced Lung Disease	44
Exposing Pre–Chronic Obstructive Pulmonary Disease: When Physiology Matters!	44
Mucus Plugs in Medium-sized Airways: A Novel Imaging Biomarker for Phenotyping Chronic Obstructive Pulmonary Disease	44
Race-based Reference Equation for Lung Function Testing in African Americans	43
“Bull’s-eye” Sign and Its Longitudinal Change on High-Resolution Computed Tomography in Pulmonary Sarcoidosis	43
Sleep Apnea and Poor COVID-19 Outcomes: Beware of Causal Intermediates and Colliders	43
Extending the Benefits of Pulmonary Rehabilitation to New Groups: Reply to Anidi et al.	43
Outcomes of Patients Denied Extracorporeal Membrane Oxygenation during the COVID-19 Pandemic in Greater Paris, France	42
Hereditary Hemorrhagic Telangiectasia with Diffuse Bronchopulmonary Arteriovenous Malformations	42
Asthma Phenotypes and COVID-19 Risk: A Population-based Observational Study	42
Risks of Mortality and Airflow Limitation in Japanese Individuals with Preserved Ratio Impaired Spirometry	42
Blood Eosinophil Counts in Chronic Obstructive Pulmonary Disease: Adding Within-Day Variability to the Equation	42
Leveraging Microbiome Composition Variability for Precision Medicine in Idiopathic Pulmonary Fibrosis	41
High-Resolution Computed Tomography-approximated Perfusion Is Comparable to Nuclear Perfusion Imaging in Severe Chronic Obstructive Pulmonary Disease	41
Lung Function as a Predictor of Cardiovascular Morbidity	41
Longitudinal Cytokine Profiling in Patients with Severe COVID-19 on Extracorporeal Membrane Oxygenation and Hemoadsorption	41
Exploring the Varied Clinical Presentation of Pediatric Asthma through the Metabolome	41
Reviewers—2023	41
Impaired Lung Function in Extremely Preterm–Born Adults in Their Fourth Decade of Life	41
October 1 Highlight	41
Spondylothoracic Dysostosis: Crab-like Rib Cage Configuration in a Neonate with Jarcho-Levin Syndrome	40
Balancing Act: Tailoring Ventilation Strategies in Acute Brain Injury	40
Undiagnosed Alpha-1 Antitrypsin Deficiency and the Perpetuation of Lung Health Inequity	40
Viscosity-Corrected Pulmonary Vascular Resistance Index in Pediatric Pulmonary Arterial Hypertension	40
What COVID-19 Has Taught Us: Ventilator-associated Pneumonia Is Back!	39
Reply to Campagna and Caci: Taking for Granted Conclusions from Studies that Cannot Prove Causality of Respiratory Symptoms and Vaping	39
Additional Thoughts on Intrinsic Dysanapsis	39
Editorial Position of the American Thoracic Society Journal Family on the Evolving Role of Artificial Intelligence in Scientific Research and Review	39
Pharmacologic Therapy for Obstructive Sleep Apnea: Are We Seeing Some Light at the End of the Tunnel?	38
Impact of the COVID-19 Pandemic on a Program to Screen for Subclinical Familial Pulmonary Fibrosis	38
Savvy About SAVI	38
Diaphragm Dysfunction as a Contributor to Breathlessness after COVID-19 Infection	38
Autofluorescence Imaging of Bronchoscopy in Mounier-Kuhn Syndrome: Negative Autofluorescence Sign	38
Beyond Air Pollution: Addressing Multifactorial Contributors to Asthma Disparities in Black and Latinx Populations	38
A Novel Protective Role for Matrix Metalloproteinase-8 in the Pulmonary Vasculature	38
When Health Disparities Hit Home: Redlining Practices, Air Pollution, and Asthma	38
Treatment of Early-Stage Non–Small Cell Lung Cancer	38
Update in Adult Asthma 2020	37
Nontraumatic Pneumocephalus after Noninvasive Ventilation	37
Obstructive Apneas in a Mouse Model of Congenital Central Hypoventilation Syndrome	37
Let’s Talk About Respiratory Swings!	37
Significant Airway Obstruction by Carbonaceous Fibrin Casts in a Child with Smoke Inhalation Injury	37
Upfront Combination Therapy for Pulmonary Arterial Hypertension: Time to Be More Ambitious than AMBITION	37
Progressive Pulmonary Fibrosis: Putting the Cart Before the Horse	37
Morphological Differences between Patient Self-inflicted and Ventilator-induced Lung Injury: An Experimental Study	37
Mycobacterium tuberculosis: A Pathogen That Can Hold Its Breath a Long Time	36
From Laënnec’s Stethoscope to the Magic of Imaging, Big Data and Artificial Intelligence: A Timeline of Precision Medicine for Patients with Chronic Obstructive Pulmonary Disease	36
Treatment Trials in Young Patients with Chronic Obstructive Pulmonary Disease and Pre–Chronic Obstructive Pulmonary Disease Patients: Time to Move Forward	36
Trends in Chronic Obstructive Pulmonary Disease Prevalence, Incidence, and Health Services Use in Younger Adults in Ontario, Canada, 2006–2016	36
Reduced COVID-19 Vaccine Response in Patients Treated with Biologic Therapies for Asthma	36
Science-based Policy Recommendations for Fine Particulate Matter in the United States	36
The Future of Highly Effective Modulator Therapy in Cystic Fibrosis	36
What Is Fatigue?	36
Tracheal Lobular Capillary Hemangioma	36
Reply to Kasugai et al.: The Mystery of Futility of Appropriate Antibiotics for Coinfection in COVID-19	35
Nonlinear Association of Occlusion Pressure at 100 MS and Patient Survival	35
Why Home Noninvasive Ventilation Should Begin in the Hospital, Not at Home	35
August 1 Highlight	35
Pulmonary Embolus and Hemoptysis Revealing Rare Intralobar Sequestration	35
Accuracy of Nasal Pressure Swing to Predict Failure of High-Flow Nasal Oxygen in Patients with Acute Hypoxemic Respiratory Failure	34
Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate-to-Severe Asthma	34
Reply to Piehler et al.: Depression Symptoms in Patients with Cystic Fibrosis Fluctuate at Baseline and Improve with Elexacaftor/Tezacaftor/Ivacaftor Therapy	34
Access to Medically Necessary Reproductive Care for Individuals with Pulmonary Hypertension	34
The Clinical Spectrum of PRISm	33
Inhaled Marijuana and the Lungs	33
Mediastinal Lymph Node Silicotic Nodules and Occupational Exposure to Respirable Crystalline Silica: A Controlled Study in Patients with Lung Cancer	33
Fossil Industry and Respiratory Societies: Time for a Clear Stand	33
Clinical Phenotype and Outcomes of Pulmonary Hypertension Associated with Myeloproliferative Neoplasms: A Population-based Study	33
Strategies for Identifying Biomarkers in Severe Asthma	33
Extracorporeal Membrane Oxygenation Transport for Severe COVID-19: Why We Can and Should!	33
Understanding How Asthma Starts: Longitudinal Patterns of Wheeze and the Chromosome 17q Locus	33
The Evolving Contours of Chronic Obstructive Pulmonary Disease	33
Adolescents and Young Adults: An Understudied, yet Likely Informative, Population in ARDS	32
Walking the Tightrope: Characterizing Acute Respiratory Distress Syndrome in Resource- and Data-constrained Settings	32
Risk and Prevention of Cardiovacular Events after Exacerbations of Respiratory Symptoms in Patients with COPD	32
What Is RSV Infection in Adults?	32
Mucosal Petechiae and Hemorrhage in Pulmonary Barotrauma in Breath-Hold Diving: Direct Observation of a Suspected Pathophysiologic Mechanism	32
Effect of Continuous Positive Airway Pressure on Arrhythmia in Atrial Fibrillation and Sleep Apnea: A Randomized Controlled Trial	32
Funding Population-based Cohorts: Still Relevant for Respiratory Epidemiology in the Era of Big Data	32
Occupational Benzene Exposure: An Unrecognized Threat for Lung Cancer Development	32
October 1 Highlight	32
Reply to Divo and Celli: To Our Knowledge, You Are Not the First…	31
An ALARMINg Type 2 Response in Cystic Fibrosis—The Key to Understanding ABPA?	31
Pulmonary FABP4 Is an Inverse Biomarker of Pneumonia in Critically Ill Children and Adults	31
Upward Diaphragm Motion on Four-Dimensional Computed Tomography in Severe Diaphragm Weakness	31
All-Cause Mortality of Staging of Airflow Obstruction by Ratio-categorized Patients with Chronic Obstructive Pulmonary Disease among the General Population	31
Chronicity Counts: The Impact of Pseudomonas aeruginosa, Staphylococcus aureus, and Coinfection in Cystic Fibrosis	31
Reply to Gan et al.: Ventilatory Burden in Obstructive Sleep Apnea: A Novel Indicator for Assessing Severity?	31
Differential Effects of Cannabis and Tobacco on Lung Function in Mid–Adult Life	31
Determinants of Lung Fissure Completeness	31