OOIR: Observatory of International Research

Papers

(The H4-Index of Immunity is 94. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
CD4+ T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection	1022
Microbiota translocation following intestinal barrier disruption promotes Mincle-mediated training of myeloid progenitors in the bone marrow	511
Nerve-racking worms	471
A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease	445
Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus	436
Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis	430
Laying the foundation for single-cell studies in bats	411
Releasing the brake: CTLA-4 loss turbocharges CAR T cells	411
How does Epstein-Barr virus trigger MS?	404
IFN-γ(g)uarding the niche—Keeping ILC2 in check	395
Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants	393
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling	353
ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING	335
The transcription factor MEF2C restrains microglial overactivation by inhibiting kinase CDK2	328
Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs	304
IgG sialylation puts lung inflammation to REST	303
Response to Are NKT cells a useful predictor of COVID-19 severity?	283
An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains	276
Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures	274
The Spleen in Local and Systemic Regulation of Immunity	262
Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma	260
Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation	239
Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance	235
Long-lasting B cell convergence to distinct broadly reactive epitopes following vaccination with chimeric influenza virus hemagglutinins	219
The best offense is a good beta-defensin	212

Navigating COVID-19: Starting a lab during the pandemic	206
Monocytes asphyxiate germinal centers	206
Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface	205
Not so aDAMant after all: Plasticity of phagocytic microglia	203
Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME	202
Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection	201
Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity	198
Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis	180
IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage	179
Contamination of isolated mouse Kupffer cells with liver sinusoidal endothelial cells	178
25-hydroxycholesterol: Gatekeeper of intestinal IgA	178
Superficial ice and deep blaze: A defense strategy of the skin	176
On blood and tissue-resident natural killer cells	173
Upper airway and brain protection by plasma cells: A local affair	172
IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis	171
Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation	167
NK resident memory cells arise from NK cells that accumulate in tissues independently of persistent local infection	165
BCG vaccination alters the epigenetic landscape of progenitor cells in human bone marrow to influence innate immune responses	160
Innate riddle of CD4+ T cells and the control of enteric infections	158
Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming	152
Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis	150
LAGging behind no more: PD-1 has a new immunotherapy partner	150
Home at last: Mixed signals guide memory T cells to residency	150
Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation	142
The microbiota control the neonatal WNT-ernet	140
Not immune to stress: LBP’s link to depression	140
Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling	140
Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity	135
IRF2 integrates inflammatory signals to balance T cell exhaustion	133
Exploring vast microbial epitope spaces	128
Metabolism in type 2 immune responses	127
Integrating population and single-cell variations in vaccine responses identifies a naturally adjuvanted human immune setpoint	126
A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus	123
Ovarian tumors orchestrate distinct cellular compositions	122
The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation	121
A no-Wnt situation for alveolar macrophage self-renewal	121
The folate way to T cell fate	121
It takes a village to skew a lymph node	119
Something old, something new: The marriage of PD-1 and IL-2	119
Many Langerhans make light work of skin immunity	119
Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer	115
Fragile-like regulatory T cells modulate opioid withdrawal in humans and mice	115
B cells! Don’t go the wrong way in this tumor	114
RIPK1: Inflamed if you do, inflamed if you don’t	114
The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation	113
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance	113
Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8+ T cell responses post SARS-CoV-2 infection	111
Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity	111
Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design	110
Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir	110

Progressive polyadenylation and m6A modification of Ighg1 mRNA maintain IgG1 antibody homeostasis in antibody-secreting cells	109
A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation	108
CD1 and MR1: An update after a long-awaited reunion	107
SARS-CoV-2 Omicron BA.1 breakthrough infection drives late remodeling of the memory B cell repertoire in vaccinated individuals	106
The CD4+ T cell response to a commensal-derived epitope transitions from a tolerant to an inflammatory state in Crohn’s disease	102
Learning from the nexus of autoimmunity and cancer	102
Analysis of antibody binding specificities in twin and SNP-genotyped cohorts reveals that antiviral antibody epitope selection is a heritable trait	101
Dopamine inhibits group 2 innate lymphoid cell-driven allergic lung inflammation by dampening mitochondrial activity	101
Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C	99
The landscape of immune dysregulation in Crohn’s disease revealed through single-cell transcriptomic profiling in the ileum and colon	99
Cytotoxic Th1 cells mushroom after fungal exposures in Crohn’s disease	98
Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine	97
Autoimmune CD4+ T cells fine-tune TCF1 expression to maintain function and survive persistent antigen exposure during diabetes	96
Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis	95
CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation	95
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression	95
PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis	95
SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic	94
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells	94