Immunity

Article	Citations
Immunology of COVID-19: Current State of the Science	1302
Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals	905
Herd Immunity: Understanding COVID-19	827
COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome	565
Inflammation in obesity, diabetes, and related disorders	533
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms	502
Cytokine Storms: Understanding COVID-19	493
Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses	432
CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity	384
Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination	352
Autophagy in inflammation, infection, and immunometabolism	352
Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway	338
Distinct Early Serological Signatures Track with SARS-CoV-2 Survival	331
Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation	307
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver	300
MDSC: Markers, development, states, and unaddressed complexity	300
The immunology of sepsis	289
The CD47-SIRPα Immune Checkpoint	288
Determinants of Resident Tissue Macrophage Identity and Function	285
Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients	283
Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity	281
SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation	279
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses	276
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors	274
Chemokines and the immune response to cancer	273

Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease	272
Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein	272
Lessons for COVID-19 Immunity from Other Coronavirus Infections	265
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging	265
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19	264
A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice	264
Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19	262
Low-Avidity CD4+ T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19	260
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis	255
Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease	250
The Neutrophil	239
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection	236
Germinal Center and Extrafollicular B Cell Responses in Vaccination, Immunity, and Autoimmunity	234
Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer	234
Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease	227
Plasma Proteomics Identify Biomarkers and Pathogenesis of COVID-19	215
Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses	214
Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions	214
Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations	212
Microglia: Immune and non-immune functions	210
Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells	204
Respiratory Virus Infections: Understanding COVID-19	202
Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis	196
Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species	190
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity	188
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation	186
SARS-CoV-2 Epitopes Are Recognized by a Public and Diverse Repertoire of Human T Cell Receptors	186
Cytotoxic CD4+ T cells in cancer: Expanding the immune effector toolbox	185
Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion	181
Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling	181
PD-1-Expressing SARS-CoV-2-Specific CD8+ T Cells Are Not Exhausted, but Functional in Patients with COVID-19	177
Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity	176
COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses	173
Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity	173
Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity	170
Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies	167
Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke	166
An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity	162
Accelerated COVID-19 vaccine development: milestones, lessons, and prospects	162
Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children	160
Fibroblast-macrophage reciprocal interactions in health, fibrosis, and cancer	159
The Intersection of Epigenetics and Metabolism in Trained Immunity	158
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy	158
FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells	153
Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity	153
Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo	151
Biology of lung macrophages in health and disease	147
Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans	147
Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor	145
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy	145

CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses	142
The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans	141
The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis	136
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19	136
Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens	136
Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity	132
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade	131
Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response	130
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses	126
Implications of Sex Differences in Immunity for SARS-CoV-2 Pathogenesis and Design of Therapeutic Interventions	124
An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells	122
T Cell Memory: Understanding COVID-19	118
CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis	118
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2	117
Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid	117
Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes	117
Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration	116
Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage	116
Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids	114
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA	114
The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts	113
Temporal maturation of neutralizing antibodies in COVID-19 convalescent individuals improves potency and breadth to circulating SARS-CoV-2 variants	112
Astrocyte-immune cell interactions in physiology and pathology	109
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake	109
Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation	109
Distinct developmental pathways from blood monocytes generate human lung macrophage diversity	109
Paneth Cell-Derived Lysozyme Defines the Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine	108
mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants	108
A subset of Kupffer cells regulates metabolism through the expression of CD36	107
m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development	106
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity	106
Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant	105
The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24	104
Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer	103
B cell memory: understanding COVID-19	102
A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages	102
Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection	100
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets	100
A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver	99
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment	98
Metabolic adaptation of lymphocytes in immunity and disease	97
Germline genetic contribution to the immune landscape of cancer	96
Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease	96
Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge	95
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control	94
Transcriptional Networks Driving Dendritic Cell Differentiation and Function	92
Innate immune mechanisms of mRNA vaccines	91
MAIT Cell Development and Functions: the Microbial Connection	91
Modification of Proteins by Metabolites in Immunity	91
Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons	90
The unique biology of germinal center B cells	90
Transition to endemicity: Understanding COVID-19	88
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors	88
Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy	86
Liver macrophages in health and disease	86
Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy	85
CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor	85
Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection	84
Resident cardiac macrophages mediate adaptive myocardial remodeling	83
Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity	82
MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function	82
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes	82
Deconstructing Mechanisms of Diet-Microbiome-Immune Interactions	81
COVID-19 vaccine access in Africa: Global distribution, vaccine platforms, and challenges ahead	81
Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins	81
Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation	80
Itch: A Paradigm of Neuroimmune Crosstalk	80
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells	80
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery	80
Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING	79
mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concern	78
CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells	78
Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses	78
The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation	78
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming	78
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas	77
Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity	77
Antibody-mediated neutralization of SARS-CoV-2	77
SARS-CoV-2 infections in children: Understanding diverse outcomes	77
Antigenic drift: Understanding COVID-19	76

Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses	75
Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells	75
Systemic Immunometabolism: Challenges and Opportunities	75
Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis	74
Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties	74
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis	74
Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques	73
Mucosal immune responses to infection and vaccination in the respiratory tract	73
Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia	73
Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease	72
Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells	72
Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis	72
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases	71
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs	71
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections	71
Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow	70
SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic	70
The pathogenesis of rheumatoid arthritis	70
IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation	70
Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection	69
Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response	68
Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function	68
Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β	68
Redefining macrophage and neutrophil biology in the metastatic cascade	68
Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche	68
Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages	67
TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures	67
Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1	67
A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope	67
Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma	66
Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut	66
Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses	66
Dietary Regulation of Immunity	66
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching	66
COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge	65
Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage	65
A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function	65
Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron	64
Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones	64
Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity	64
Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment	64
Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring	64
Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development	62
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade	62
Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity	61
Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3+ Regulatory T Cells via a miR-342-Dependent Mechanism	61
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes	61
Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses	61
Atlas of currently available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/BA.1.1/BA.2/BA.3	61
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway	61
A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation	60
Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy	60
Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses	60
Adrenergic regulation of the vasculature impairs leukocyte interstitial migration and suppresses immune responses	60
The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries	60
SARS-CoV-2 in immunocompromised individuals	59
Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses	59
Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation	59
Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer	58
Principles of regulatory T cell function	57
The cancer-immunity cycle: Indication, genotype, and immunotype	57
Emerging roles of innate and adaptive immunity in Alzheimer’s disease	57
Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation	57
Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer	57
Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers	56
Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93	55
Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress	55
Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges	54
The COVID-19 Serology Studies Workshop: Recommendations and Challenges	54
Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function	54
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity	54
In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma	53
Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers	53
Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites	52
Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles	52
Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection	52
T Cell Receptor Is Required for Differentiation, but Not Maintenance, of Intestinal CD4+ Intraepithelial Lymphocytes	52
Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation	52
Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma	52
APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis	52
The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses	51
Nucleic Acid Sensors as Therapeutic Targets for Human Disease	51
Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response	50
Dietary and Microbial Determinants in Food Allergy	50
β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression	50
Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development	50
Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells	50
Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells	49
GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair	49
An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development	49
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis	49
Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation	48
The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination	48
Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment	48
Single-cell immunology: Past, present, and future	48