Nature Medicine

Article	Citations
SCOTUS v. reproductive health in United States	1559
Rise in ambient temperature is associated with increased mortality in Latin America	1463
Telemonitoring for complicated pregnancies	1458
How virtual reality therapy is shaping mental health	957
LLMs get a medical education	789
Questionable role of new techniques in IVF embryo culture	761
A genetic test to predict adverse drug reactions	719
Easing the pain of endometriosis	671
Liquid biopsies and tumor mutational burden: the cutoff conundrum	640
A global metric of immune health	622
Author Correction: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology	602
Solving medicine’s data bottleneck: Nightingale Open Science	573
Recapitulating sensory feedback in artificial skin	570
In vivo gene editing for inherited vision loss	569
A fluid biomarker accurately detects tau aggregate pathology in Alzheimer’s disease	566
First tumor-agnostic approval for an ADC	519
Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids	516
Not all KRAS-mutated pancreatic cancers are equal — mutant dosage matters	491
Longitudinal analysis shows how microbiome changes might influence responses to immune checkpoint blockade	476
Author Correction: Financial incentives for COVID-19 vaccines in a rural low-resource setting: a cluster-randomized trial	467
Author Correction: Dapagliflozin in heart failure with improved ejection fraction: a prespecified analysis of the DELIVER trial	449
An AI chatbot for talking therapy referrals	438
Can an implanted minipump deliver for diabetes patients?	424
The capacity of brain circuits to enhance psychiatry	423
HIV prevention through PrEP in cisgender women	421

Author Correction: Pembrolizumab and cabozantinib in recurrent metastatic head and neck squamous cell carcinoma: a phase 2 trial	417
Estimating the total effect of anthropogenic climate change on human health and wellbeing	416
Promoting gender equity in the scientific and health workforce is essential to improve women’s health	412
Combating vaccine revisionism	411
HIPAA is a misunderstood and inadequate tool for protecting medical data	409
Gene-edited pig liver successfully transplanted into human	409
FDA approves first drug to delay type 1 diabetes	405
The WHO genomics program of work for equitable implementation of human genomics for global health	396
Estimating future heat-related and cold-related mortality under climate change, demographic and adaptation scenarios in 854 European cities	393
Supported decision-making can advance clinical research participation for people with disabilities	382
Changing climate and socioeconomic factors contribute to global antimicrobial resistance	377
Anemia in women — an intractable problem that requires innovative solutions	376
Publisher Correction: Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes	375
In utero origin of myelofibrosis presenting in adult monozygotic twins	372
Author Correction: Digital consults in heart failure care: a randomized controlled trial	365
The role of research in China’s successful elimination of malaria	362
Concerns about the Burden of Proof studies	360
Allogeneic CD5-specific CAR-T therapy for relapsed/refractory T-ALL: a phase 1 trial	358
PD-L1 and the dawn of modern cancer immunotherapy	357
The inconvenient reality of AI-assisted embryo selection in IVF	354
The uncertain science of preimplantation and prenatal genetic testing	348
Targeted therapy for osteoarthritis: progress and pitfalls	342
Integrating the environmental and genetic architectures of aging and mortality	338
Author Correction: Unexplained post-acute infection syndromes	334
An explainable foundation model for drug repurposing	333
Low-voltage-area ablation for persistent atrial fibrillation: a randomized controlled trial	330
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial	327
Will ChatGPT transform healthcare?	320
Continuous glucose monitoring and intrapersonal variability in fasting glucose	320
Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial	320
The landscape of mRNA nanomedicine	319
Licensed H5N1 vaccines generate cross-neutralizing antibodies against highly pathogenic H5N1 clade 2.3.4.4b influenza virus	319
Hippocampal network activity forecasts epileptic seizures	314
Pregnant and lactating women should be included in clinical trials for cardiovascular disease	311
Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease	308
Phenotypic signatures in clinical data enable systematic identification of patients for genetic testing	303
In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial	299
A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s disease	297
Molecular classification to refine surgical and radiotherapeutic decision-making in meningioma	297
Remotely delivered weight management for people with long COVID and overweight: the randomized wait-list-controlled ReDIRECT trial	295
IL-6 inhibition with clazakizumab in patients receiving maintenance dialysis: a randomized phase 2b trial	293
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy	291
CanScreen5, a global repository for breast, cervical and colorectal cancer screening programs	291
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants	289
Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality	287
Pembrolizumab for advanced urothelial carcinoma: exploratory ctDNA biomarker analyses of the KEYNOTE-361 phase 3 trial	287
Trastuzumab deruxtecan in HER2-positive breast cancer with brain metastases: a single-arm, phase 2 trial	285
Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19	283
AI as a new paradigm for risk-based screening for breast cancer	281
Integrated image-based deep learning and language models for primary diabetes care	280

Patritumab deruxtecan in leptomeningeal metastatic disease of solid tumors: the phase 2 TUXEDO-3 trial	280
Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses	277
Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial	272
Urgent action is needed to confront artemisinin partial resistance in African malaria parasites	269
WHO sets research agenda for refugee and migrant health	267
Machine learning improves prediction of clinical outcomes for invasive breast cancers	266
The Yearbook	265
An anti-obesity drug from the diabetes toolbox	263
An outdated loophole is letting faulty lab tests hit the market	262
Rethinking aspirin for heart health	260
High COVID-19 death toll in Africa	260
Health in the Amazon	259
The visible and hidden mortality caused by flooding	257
Mapping the cellular landscape of the brain	255
Acquired blood mutations cause acute kidney injury via dysregulated inflammation	252
Familial confounding in the associations between maternal health and autism	251
Anti-amyloid could help prevent genetic form of Alzheimer’s disease	251
Steps to prevent and respond to an H5N1 epidemic in the USA	250
Technology-assisted cognitive-behavioral therapy for perinatal depression delivered by lived-experience peers: a cluster-randomized noninferiority trial	248
Oral obeldesivir provides postexposure protection against Marburg virus in nonhuman primates	246
Microbiome–metabolome dynamics associated with impaired glucose control and responses to lifestyle changes	246
Simulation-based estimates and projections of global, regional and country-level maternal mortality by cause, 1990–2050	245
A benchmarking crisis in biomedical machine learning	245
The expanding universe of checkpoint inhibitors for nasopharyngeal cancer	244
Reply to Guyton, J. R. & Boden, W. E.; Schreiber, S. et al.	242
Open Letter to G7 and G20 leaders: resolve global crises to secure our future	240
From neoadjuvant to organ-sparing immunotherapy for colorectal cancer	240
Coproducing health research with Indigenous peoples	239
Immune reconstitution inflammatory syndrome drives emergence of HIV drug resistance from multiple anatomic compartments in a person living with HIV	236
An African One Health network for antimicrobial resistance and neglected tropical diseases	236
A gene-by-sex interaction contributes to liver disease susceptibility in women	235
Health benefits of calorie restriction	232
How patient advocates influence health policy	231
Prenatal exposure to famine affects lifelong health	231
siRNA therapy lowers triglycerides in patients with rare condition	226
Meningioma risk stratification with a targeted gene-expression biomarker	225
The effect of embryonic genome imbalances on pregnancy	223
Using genetics to predict toxicity of cancer immunotherapy	220
Brain pathology of COVID-19	220
Menstrual health without stigma	220
Author Correction: Autologous T cell therapy for PRAME+ advanced solid tumors in HLA-A*02+ patients: a phase 1 trial	219
Use of mobile diagnostics and digital clinical trials in cardiology	219
Author Correction: Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury	216
AI-generated text may have a role in evidence-based medicine	213
Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial	212
D3S-001 in advanced solid tumors with KRASG12C mutations: a phase 1 trial	210
Self-improving generative foundation model for synthetic medical image generation and clinical applications	209
Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts	208
Multi-omic profiling a defined bacterial consortium for treatment of recurrent Clostridioides difficile infection	207
Personalized brain circuit scores identify clinically distinct biotypes in depression and anxiety	207
Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial	205
Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial	205
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations	202
Distinct mechanisms of long-term virologic control in two HIV-infected individuals after treatment interruption of anti-retroviral therapy	202
Clinical AI tools must convey predictive uncertainty for each individual patient	200
The airway microbiome mediates the interaction between environmental exposure and respiratory health in humans	200
Mutations in the U4 snRNA gene RNU4-2 cause one of the most prevalent monogenic neurodevelopmental disorders	196
Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis	196
Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial	195
Dupilumab in patients with prurigo nodularis: two randomized, double-blind, placebo-controlled phase 3 trials	194
Using unlabeled data to enhance fairness of medical AI	193
Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination	193
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia	193
A digital health algorithm to guide antibiotic prescription in pediatric outpatient care: a cluster randomized controlled trial	192
Mpox continues to spread in Africa and threatens global health security	192
Smartwatch- and smartphone-based remote assessment of brain health and detection of mild cognitive impairment	192
Evaluation of the extended efficacy of the Dengvaxia vaccine against symptomatic and subclinical dengue infection	191
Determinants of COVID-19 vaccination status and hesitancy among older adults in China	190
Maternal diabetes and risk of attention-deficit/hyperactivity disorder in offspring in a multinational cohort of 3.6 million mother–child pairs	190
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity	189
Salt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial	188
The limits of fair medical imaging AI in real-world generalization	188
Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults	187
A meta-analysis of GFR slope as a surrogate endpoint for kidney failure	186
Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial	186
Prospective implementation of AI-assisted screen reading to improve early detection of breast cancer	186
Genome-wide polygenic score to predict chronic kidney disease across ancestries	186
Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer	185
Emerging diagnostics and therapeutics for Alzheimer disease	185
Advancing global antibiotic research, development and access	184

An integrated cell atlas of the lung in health and disease	183
Gene therapy for alcohol-use disorder	182
Could video games be good for your health?	181
Pig-to-human transplants inch closer to reality	179
ALS therapy hits molecular mark but misses clinical one	179
A human brain circuit for addiction remission	177
A smart solution for detecting ear problems	175
A pinch of salt for heart disease	175
Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial	175
Challenges with benchmarking of MDMA-assisted psychotherapy	174
The impact of school opening model on SARS-CoV-2 community incidence and mortality	172
Immunogenicity and safety of the CoronaVac inactivated vaccine in patients with autoimmune rheumatic diseases: a phase 4 trial	170
Deciphering the heritability of human height	170
The unseen climate health risks of antimicrobial resistance in urban informal settlements	170
Targeted radiation adds precision to cancer therapy	169
Author Correction: T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection	169