Journal of Ocular Pharmacology and Therapeutics

Article	Citations
Eyes on New Product Development	64
Eyes on New Product Development	35
Survival of Neural Progenitors Derived from Human Embryonic Stem Cells Following Subretinal Transplantation in Rodents	31
Topical Porphyrin Antioxidant Protects Against Ocular Surface Pathology in a Novel Rabbit Model for Particulate Matter-Induced Dry Eye Disease	30
Lidocaine Hydrochloride Gel for Ocular Surface Anesthesia: Pharmacokinetic Evaluation and Randomized Placebo-Controlled Trial in China	20
Novel Combined Lidocaine/Povidone Iodine Delivery System for Preintravitreal Injection	20
Corticosteroid as Treatment in Infective Conjunctivitis: A Systematic Literature Review and Meta-Analysis	19
Review of Janus Kinase Inhibitors as Therapies for Noninfectious Uveitis	18
N-Methyl-d-Aspartate-Induced Excitotoxicity and Its Impact on the Renin–Angiotensin System in Retinal Tissue	16
Eyes on New Product Development	15
Are Alpha-2 Adrenergic Agonists Being Used in Infants?	15
Comment on: “Duration of Bare Sclera Pterygium Surgery Combined with Mitomycin C with and Without Tranexamic Acid: A Randomized Double-Blind Controlled Trial”	13
Clinical Pharmacokinetics of Atropine Administered Ocularly Using an Ultrasensitive Bioanalytical Assay	13
Age-Related Macular Degeneration Pathophysiology and Therapeutic Potential of Tocotrienols: An Update	13
Eyes on New Product Development	12
Eyes on New Product Development	11
Development of Anterior Segment Focused Biologic Therapies to Regenerate Corneal Tissue for the Treatment of Disease: Drug Development Experience	11
Prostaglandin-Associated Periorbitopathy Symptom Alleviation After Switching Prostaglandin F Receptor Agonist to EP2 Receptor Agonist in Patients with Glaucoma	11
Acknowledgment of Reviewers 2023	9
Kaempferol Protects Against Retinal Photoreceptor Degeneration in a Mouse Model of Light-Induced Retinal Injury	9
Ex Vivo Pig Eye Model for Studying Diffusion of Acylcarnitines with Different Physicochemical Properties	9
Prevention of Choroidal Thinning by 0.01% Atropine Administered 24 h Before Exposure to Hyperopic Blur in Young Myopes	9
Differential Effects of Benzalkonium Chloride on Human Trabecular Meshwork Cells Not Treated or Treated with Transforming Growth Factor-β2 or Dexamethasone	9
Comparative Efficacy of Topical Ophthalmic Ganciclovir and Oral Famciclovir in Cats with Experimental Ocular Feline Herpesvirus-1 Epithelial Infection	9
Unraveling the Complexities of Severe Acute Respiratory Syndrome Coronavirus 2: A Comprehensive Ophthalmic and Systemic Perspective	9

AOPT XV Biennial Meeting: Restoring Vision Through Regeneration	9
Interspecialty Opioid Prescribing Patterns in Ophthalmology Following Declaration of a Public Health Emergency	8
Eyes on New Product Development	8
Gene Delivery of a Caspase Activation and Recruitment Domain Improves Retinal Pigment Epithelial Function and Modulates Inflammation in a Mouse Model with Features of Dry Age-Related Macular Degenerat	8
Context-Dependent Effects of the Ketogenic Diet on Retinal Ganglion Cell Survival and Axonal Regeneration After Optic Nerve Injury	8
Ocular Safety and Toxicokinetics of Bevacizumab-bvzr (Zirabev), a Bevacizumab Biosimilar, Administered to Cynomolgus Monkeys by Intravitreal Injection	8
Preformulation-Assisted Design of Ketorolac Tromethamine for Effective Ophthalmic Delivery	7
Effectiveness of Topical Cyclosporin A 0.1%, Diquafosol Tetrasodium 3%, and Their Combination, in Dry Eye Disease	7
Transport of Vitamin E from Ethanol/Water Solution into Contact Lenses and Impact on Drug Transport	7
Eyes on New Product Development	7
Effect of Chemical Injury on Autophagy in Canine Corneal Stromal Fibroblasts	7
A Comparative Study on Efficacy of Intraocular Pressure Lowering of Two Fixed-Dose Antiglaucoma Drug Combination Brinzolamide-Brimonidine Versus Latanoprost-Timolol in Primary Open-Angle Glaucoma and	7
Eyes on New Product Development	7
Eyes on New Product Development	7
N-of-1 Clinical Trials: A Scientific Approach to Personalized Medicine for Patients with Rare Retinal Diseases Such as Retinitis Pigmentosa	7
Regulating Generic Ophthalmologic Drug Bioequivalence—Envisioning Accessibility for Patients	7
Benzalkonium Chloride-Induced Corneal Epithelial Injury in Rabbit Reduced by Rebamipide	6
Role of NADPH Oxidase 4 on Dry Eye Syndrome in Mice	6
Inhibition of Experimental Corneal Neovascularization by the Tight Junction Protein ZO-1	6
Another Etiological Factor of Meibomian Gland Loss in Patients with Polycystic Ovary Syndrome: Inflammation	6
Dual Delivery of Cyclosporin A and Etodolac Using Polymeric Nanocapsules in a Rabbit Eye Model: Ocular Biodistribution and Pharmacokinetic Study	6
Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: Results from the VISIONARY Study Population in Spain	6
Eyes on New Product Development	6
Neuritin 1 Drives Therapeutic Preservation of Retinal Ganglion Cells in an Ex Vivo Human Glaucoma Model	6
Inhibition of Connective Tissue Growth Factor Expression in Adult Retinal Pigment Epithelial-19 Cells by Blocking Yes-Associated Protein/Transcriptional Coactivator with PDZ-Binding Motif Activity	6
Neurokinin-1 Receptor Antagonism Reduces Nonallergic Ocular Redness in a Rabbit Model	6
Metabolomic Disparities in Intraocular Fluid Across Varied Stages of Cataract Progression: Implications for the Analysis of Cataract Development	6
Comparisons of α2-Adrenergic Agents, Medetomidine and Xylazine, with Pentobarbital for Anesthesia: Important Pitfalls in Diabetic and Nondiabetic Rats	6
Factors Related to Axial Length Elongation in Myopic Children Who Received 0.05% Atropine Treatment	5
Extracellular Vesicles Derived from Adipose-Derived Mesenchymal Stem Cells Alleviate Apoptosis and Oxidative Stress of Retinal Pigment Epithelial Cells Through Activation of Nrf2 Signaling Pathway	5
The Results of Preoperative Use of Topical Brimonidine in Strabismus Surgery	5
Antibiotic Prescribing Patterns Among U.S. Ophthalmologists and Optometrists from 2018 to 2021 in the Medicare Part D Database	5
Therapeutic Profile of Human Umbilical Cord Blood Serum and Autologous Serum Therapies in Treatment of Ocular Surface Disorders: A Pilot Study	5
Mammalian Target of Rapamycin Inhibitor Rapamycin Alleviates 7-Ketocholesterol Induced Inflammatory Responses and Vascular Endothelial Growth Factor Elevation by Regulating MAPK Pathway in Human Retin	5
ZD6474 Attenuates Fibrosis and Inhibits Neovascularization in Human Pterygium by Suppressing AKT-mTOR Signaling Pathway	5
Eyes on New Product Development	5
Topical Losartan: Practical Guidance for Clinical Trials in the Prevention and Treatment of Corneal Scarring Fibrosis and Other Eye Diseases and Disorders	5
Celastrol Regulates the Secretion of Interleukin-17 in Patients with Sympathetic Ophthalmia Through Signal Transducer and Activator of Transcription 3	5
Discovery and Development of the Quininib Series of Ocular Drugs	5
Acknowledgment of Reviewers 2021–2022	5
Retinal and Choroidal Neovascularization Antivascular Endothelial Growth Factor Treatments: The Role of Gene Therapy	5
Aquaporin5-Targeted Treatment for Dry Eye Through Bioactive Compounds and Gut Microbiota	5
MicroRNA Therapy for Dry Eye Disease	5
Characteristics of Mitomycin C-Loaded Peptide Hydrogel In Vitro and Antiscarring Effects in Rat Ocular Injury Model	5
V-ATPase Regulates Retinal Progenitor Cell Proliferation During Eye Regrowth in Xenopus	4
Basic Fibroblast Growth Factor Supports the Function of Limbal Niche Cells via the Wnt/β-Catenin Pathway	4
Intracameral Drug Delivery: A Review of Agents, Indications, and Outcomes	4
Novel Peptide NT/K-CRS Derived from Kringle Structure of Neurotrypsin Inhibits Neovascularization In Vitro and In Vivo	4
Effects of Regular/Dilute Proparacaine Anesthetic Eye Drops in Combination with Ophthalmic Antibiotics on Corneal Wound Healing	4
Tauroursodeoxycholic Acid Alleviates Endoplasmic Reticulum Stress-Mediated Visual Deficits in Diabetic tie2-TNF Transgenic Mice via TGR5 Signaling	4

Eyes on New Product Development	4
Eyes on the Prize: Decoding the Ophthalmic Product Regulations and Intricacies of the U.S. Food and Drug Administration Approval	4
Regulatory Requirements of Biosimilars: Drug Development in Ophthalmology, Part 1	4
Ocular Distribution and Pharmacokinetics of 8-Oxo-2′-Deoxyguanosine: A Novel Therapeutic Candidate of Ocular Surface Diseases	4
NCX 1741, a Novel Nitric Oxide-Donating Phosphodiesterase-5 Inhibitor, Exerts Rapid and Long-Lasting Intraocular Pressure-Lowering in Cynomolgus Monkeys	4
Hyperopic LASIK Enhanced by Pharmacological Treatment of Presbyopia	4
Call for Special Issue Papers: Ocular Drug Delivery Technology Special Issue	4
Two Decades of Research in Drug Delivery Systems for the Treatment of Diseases of the Posterior Segment of the Eye	4
Intraocular Axon Regeneration in a Model of Penetrating Eye Injury	4
Grading the Severity of Damage to the Perijunctional Actomyosin Ring and Zonula Occludens-1 of the Corneal Endothelium by Ensemble Learning Methods	4
Eyes on New Product Development	4
Regeneration and Vision Restoration	4
A Multicenter, Randomized, Double-Blind Evaluation of the Efficacy of TJO-087 Versus 0.05% Cyclosporine A in Moderate to Severe Dry Eye	3
Novel Photodynamic/Photothermal Treatment of Fungal Keratitis Using Rose Bengal-Loaded Polypyrrole-Gold Nanoparticles in Wistar Albino Rats	3
Topical Administration of Bevacizumab to Facilitate the Functional Filtering Bleb After Trabeculectomy in the Rabbit	3
Novel Drug Delivery Systems for the Management of Fungal Keratitis	3
Ocular Treatments Targeting Separate Prostaglandin Receptors in Mice Exhibit Alterations in Intraocular Pressure and Optic Nerve Lipidome	3
Use of a Cationic Emulsion of Latanoprost to Treat Glaucoma Patients with Ocular Surface Disease: A Preclinical Review	3
Effects of Topical Antiglaucomatous Medications on Conjunctival Thickness: A Prospective Anterior Segment Optical Coherence Tomography Study	3
Innovative Optical Technologies in Ophthalmology and Eye Research	3
Evaluation of Retinal and Choroidal Microcirculation Alterations After a Single Dose of Oral 5-mg Tadalafil: A Prospective Pilot Optical Coherence Tomography Angiography Study	3
Pharmacokinetic and Ocular Toxicity Evaluation of Latanoprost Ophthalmic Solution, 0.005%, with Preservative Level Reduced to Below the Limit of Quantitation	3
Functional and Morphological Responses to Fluocinolone Acetonide 0.19 mg in Noninfectious Uveitic Macular Edema Evaluated as the Area-Under-the-Curve	3
AG-920 (Articaine) Ophthalmic Solution: A Masked, Active-Controlled Evaluation of Its Local Anesthetic Efficacy and Safety in Pediatric Patients	3
Eyes on New Product Development	3
Review of Risk Factors and Complications of Anterior Migration of Ozurdex Implant: Lessons Learnt from the Previous Reports	3
Eyes on New Product Development	3
Using a Novel, Subconjunctival, Sustained-Release Mitomycin C Formulation in a Rabbit Model of Filtration Surgery with Gel Stent Implantation	3
Blood-Derived Eye Drops for the Treatment of Corneal Neuropathic Pain	3
Ocular Surface Disease in Glaucoma Patients Randomized to Benzalkonium Chloride-Containing Latanoprost and Preservative-Free Bimatoprost	3
Pharmacological Therapy of Proliferative Vitreoretinopathy: Systematic In Vitro Comparison of 36 Pharmacological Agents	2
Structure–Function Relationships in the Rodent Streptozotocin-Induced Model for Diabetic Retinopathy: A Systematic Review	2
Corticosteroids in the Management of Infectious Keratitis: A Concise Review	2
Real-World Clinical Impact of Netarsudil 0.02% at an Urban Safety-Net Hospital	2
Sustained Release of Antibody-Conjugated DNA Nanocarriers from a Novel Injectable Hydrogel for Targeted Cell Depletion to Treat Cataract Posterior Capsule Opacification	2
Efficacy of Intravitreal Dexamethasone After Combined Phacoemulsification and Pars Plana Vitrectomy for Diabetic Tractional Retinal Detachments	2
Nanotechnology in Retinal Disease: Current Concepts and Future Directions	2
Eyes on New Product Development	2
Gene and Stem Cell-Based Therapies: Emerging Therapeutic Modalities in Ophthalmology	2
Comparison of Proparacaine, Tetracaine, and Oxybuprocaine in Corneal Sensitivity Measurement	2
Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for the Journal of Ocular Pharmacology and Therapeutics	2
Pharmacological Profile and Ocular Hypotensive Effects of Cromakalim Prodrug 1, a Novel ATP-Sensitive Potassium Channel Opener, in Normotensive Dogs and Nonhuman Primates	2
Ophthalmic Nanoemulsion Fingolimod Formulation for Topical Application	2
13-cis Retinoic Acid-Mediated Modulation of Human Meibomian Gland Epithelial Cells Development: Implications for In Vitro Modeling of Meibomian Gland Dysfunction	2
Evaluation of Dose–Response Relationship in Novel Extended Release of Targeted Nucleic Acid Nanocarriers to Treat Secondary Cataracts	2
Carbonic Anhydrase Inhibitor Modulation of Intraocular Pressure Is Independent of Soluble Adenylyl Cyclase	2
Comprehensive Preclinical Assessment of ADVM-022, an Intravitreal Anti-VEGF Gene Therapy for the Treatment of Neovascular AMD and Diabetic Macular Edema	2
Intravitreal Brolucizumab and Aflibercept for Polypoidal Choroidal Vasculopathy	2
Medicare Part D Glaucoma Drug Prescribing Patterns by Ophthalmologists from 2018 to 2022	2
Internalization of Angiotensin-(1–12) in Adult Retinal Pigment Epithelial-19 Cells	2
The Effect of Oral Vitamin A Supplementation on Chalazion in Young Children with Vitamin A Deficiency: A Pilot Study	2
Eyes on New Product Development	2
NCX 470 Restores Ocular Hemodynamics and Retinal Cell Physiology After ET-1-Induced Ischemia/Reperfusion Injury of Optic Nerve and Retina in Rabbits	2
Clinical Efficacy of an Eyedrop Containing Hyaluronic Acid and Ginkgo Biloba in the Management of Dry Eye Disease Induced by Cataract Surgery	2
The Transcriptome Profile of Retinal Pigment Epithelium and Müller Cell Lines Protected by Risuteganib Against Hydrogen Peroxide Stress	2
Effects of Rebamipide for Dry Eye on Optical Quality and Efficacy: A Systematic Review and Meta-Analysis	2
Novel Drug Delivery Systems to Improve the Treatment of Keratitis	2
ROCK Inhibitors as an Alternative Therapy for Corneal Grafting: A Systematic Review	2
Eyes on New Product Development	2
Effect of Age and Viscosity on Duration of Corneal Anesthesia with Topical 2% Lidocaine Administration	2
Toxicity Evaluation of a Novel Rapamycin Liposomal Formulation After Subconjunctival and Intravitreal Injection	1
Novel Lipids of the Rabbit Harderian Gland Improve Tear Stability in an Animal Model of Dry Eye Disease	1
Clinical Results of the Use of a Combined Solution of 0.5% Carboxymethylcellulose, 0.9% Glycerin, and 3% Trehalose for the Treatment of Dry Eye Disease	1
Editor's Letter	1
Surgical Procedures in the Treatment of Dry Eye Disease	1
Trends in Ophthalmological Patents, 2005–2020	1
Simultaneous Effects of a Selective EP2 Agonist, Omidenepag, and a Rho-Associated Coiled-Coil Containing Protein Kinase Inhibitor, Ripasudil, on Human Orbital Fibroblasts	1
Phospho-Sulindac (OXT-328) Inhibits Dry Eye Disease in Rabbits: A Dose-, Formulation- and Structure-Dependent Effect	1
Duration of Vascular Endothelial Growth Factor Suppression After Intravitreal Injection of Brolucizumab and Aflibercept in Macaque Eyes	1
Eyes on New Product Development: Regulations, Generics, and Disruptive Technologies	1
Neuroprotective Effects of Citicoline on Methanol-Intoxicated Retina Model in Rats	1
Sustained Delivery of Olopatadine from Vitamin-E Loaded Contact Lenses	1
Effects of Diquafosol Sodium Ophthalmic Solution on Tear Film Matrix Metallopeptidase-9 and Corneal Nerve Density in Patients with Type 2 Diabetic Dry Eye	1
Eyes on New Product Development	1
Cysteinyl Leukotriene Receptor Antagonism by Montelukast to Treat Visual Deficits	1
Letter to the Editor: Steroid/AntiVascular Endothelial Growth Factor Combination Therapy for Neovascular Age-Related Macular Degeneration	1
Efficacy of Intravitreal Multi-Characteristic Opsin (MCO-010) Optogenetic Gene Therapy in a Mouse Model of Leber Congenital Amaurosis	1
Eyes on New Product Development	1
2018-2020 Reviewer Acknowledgment	1
Complement Factor B Inhibition or Deletion Is Not Sufficient to Prevent Neurodegeneration in a Murine Model of Glaucoma	1

Eyes on New Product Development	1
Inhibition of HDAC1 and 3 in the Presence of Systemic Inflammation Reduces Retinal Degeneration in a Model of Dry Age-Related Macular Degeneration	1
Pharmacokinetics of Sirolimus Eye Drops Following Topical Ocular Administration in Rabbits	1
The Development of a SIBS Shunt to Treat Glaucoma	1
Magic Bullets: The Coming Age of Meaningful Pharmacological Control of the Corneal Responses to Injury and Disease	1
Cytotoxic, Apoptotic, and Oxidative Effects of Preserved and Preservative-Free Brimonidine in a Corneal Epithelial Cell Line	1
The JOPT Story: 40 Years of Growth and Focus	1
Eyes on New Product Development	1
Nanoliposomes for Sensing Local Osmolarity of the Tear Film on the Corneal Surface	1
Improved Topical Ophthalmic Natamycin Suspension for the Treatment of Fungal Keratitis	1
7,8-Dihydroxyflavone Simultaneously Provides Neuroprotection of Retinal Explants and Proangiogenesis of Human Umbilical Vein Endothelial Cells via the Tropomyosin-Related Kinase Receptor B Signaling P	1
Phase 2b, Randomized, 3-Month, Dose-Finding Study of Sepetaprost in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: The ANGEL Study	1
Effects of Bone Marrow and Adipose-Derived Mesenchymal Stem Cells on microRNA Expressions in Acute Alkaline Corneal Burn	1
Eyes on New Product Development	1
Effects of Anti-Vascular Endothelial Growth Factor Drugs Before and After Pars Plana Vitrectomy in Patients with Polypoidal Choroidal Vasculopathy and Vitreous Hemorrhage	1
Duration of Bare Sclera Pterygium Surgery Combined with Mitomycin C with and Without Tranexamic Acid: A Randomized Double-Blind Controlled Trial	1
Eyes on New Product Development	1
Pre-Emptive Topical Ketorolac Tromethamine 0.5% for Panretinal Photocoagulation	1
Difluprednate-Hydroxypropyl-β-Cyclodextrin-Based Ophthalmic Solution for Improved Delivery in a Porcine Eye Model	1
The Effect of Citicoline on Ethambutol Optic Neuropathy: Histopathology and Immunohistochemistry Analysis of Retina Ganglion Cell Damage Level in Rat Model	1
Neurotrophic Factors Secreted by Induced Pluripotent Stem Cell-Derived Retinal Progenitors Promote Retinal Survival and Preservation in an Adult Porcine Neuroretina Model	1
Solanum nigrum Toxicity and Its Neuroprotective Effect Against Retinal Ganglion Cell Death Through Modulation of Extracellular Matrix in a Glaucoma Rat Model	1
Efficacy of Topical 0.05% Cyclosporine A for Ocular Surface Disease Related to Topical Anti-Glaucoma Medications	1
Intraocular Pressure-Lowering Efficacy of a Sustained-Release Bimatoprost Implant in Dog Eyes Pretreated with Selective Laser Trabeculoplasty	1
Eyes on New Product Development	1
Impact of Various Concentrations of Low-Dose Atropine on Pupillary Diameter and Accommodative Amplitude in Children with Myopia	1
Chimeric Helper-Dependent Adenoviruses Transduce Retinal Ganglion Cells and Müller Cells in Human Retinal Explants	1
NCX 470 Reduces Intraocular Pressure More Effectively Than Lumigan in Dogs and Enhances Conventional and Uveoscleral Outflow in Non-Human Primates and Human Trabecular Meshwork/Schlemm's Canal Constru	1
Oxidative Stress Induces a Breakdown of the Cytoskeleton and Tight Junctions of the Corneal Endothelial Cells	1
Anti-Inflammatories in the Treatment of Dry Eye Disease: A Review	1
Diagnostic Uses of Common Eye Drops	1
Mucoadhesive Polymers Enhance Ocular Drug Delivery: Proof of Concept Study with 0.5% Tropicamide in Dogs	1
Vitamin B3 Supplementation for Optic Neuropathies: A Comprehensive Review	1
Changes in Ocular Biometric Parameters Over a 24-Hour Period in Ocular Hypertensive Patients	1
Letter to the Editor: Effect of Aqueous Tears on Topical Fluorescein Tracer Emission Signal from Cornea and Anterior Chamber	1
Eyes on New Product Development: Regulations, Generics, and Disruptive Technologies	1
One-Year Efficacy and Safety of Omidenepag Isopropyl in Patients with Normal-Tension Glaucoma	1
Preclinical Evaluation of a Novel Once-a-Day Brimonidine Ophthalmic Nanosuspension	1
Ocular Side Effects of Bisphosphonates: A Review of Literature	1
Ribonucleic Acid (RNA) Therapeutics: Role of Long Noncoding RNAs in Ocular Vascular Diseases	1
Pharmacokinetics of Sirolimus in a Novel Liposome Delivery System in Selected Ocular Tissues and Plasma Following a Single Subconjunctival Injection in Dutch Belted Rabbits	1