Journal of Investigative Medicine

Article	Citations
CIAP1/2 can regulate the inflammatory response and lung injury induced by apoptosis in septic rats	162
The scientific value of medical student research: The experience at the Arrow Program for Medical Research Education	126
Stem bark of Fraxinus rhynchophylla ameliorates the severity of pancreatic fibrosis by regulating the TGF-β/Smad signaling pathway	103
Basic Fibroblast Growth Factor Inhibits Aortic Valvular Interstitial Cells Calcification via Notch1 Pathway	44
Circulating lipid and lipoprotein profiles and their correlation to cardiac function and cardiovascular outcomes in patients with acute myocardial infarction	43
Telomere Length in Patients with Alcohol-Associated Liver Disease: A Brief Report	40
Diagnostic role of multislice spiral computed tomography combined with clinical manifestations and laboratory tests in acute appendicitis subtypes	35
Does anticoagulation in combination with immunosuppressive therapy prevent recurrent thrombosis in Behçet’s disease?	30
The prevalence and characteristics of misinformation on “TikTok” related to cirrhosis and liver disease: A comparative analysis of accurate and misleading content	27
The Data Error Criteria (DEC) for retrospective studies: development and preliminary application	26
CircZFR involves propofol-triggered ferroptosis in lung cancer cells through the IGF2BP2/GPX4 axis	25
Magnesium intake is associated with the metabolically healthy obese phenotype	22
EXPRESS: Gender-Specific Effects of Appendectomy on Inflammatory Bowel Disease: Increased Odds of Crohn’s Disease and Decreased Odds of Ulcerative Colitis in Women—An Analysis Using the National Inpat	22
Hyperbilirubinemia in hospitalized patients: Etiology and outcomes	20
Non-Surgical Animal Model of Gastroesophageal Reflux Disease by Overeating Induced in Mice	20
Colonoscopy in the young: Rethinking the yield	20
COVID-19-related mortality in Texas border counties vs non-border counties	19
The role of pentraxin 3 and oxidative status in the prognosis of multiple myeloma	19
Evaluation of Glycemic Control in Critically ill Patients with Bacteremia: A Retrospective, Single-Center Cohort Study	18
COVID-19 Pneumonia in Patients with Impaired Fasting Glucose, Newly Diagnosed Diabetes and Pre-Existing Diabetes: A Tertiary Center Experience	17
Tocilizumab in Patients Hospitalized with COVID-19 Pneumonia: Systematic Review and Meta-Analysis of Randomized Controlled Trials	16
Serum Talin-1 and Pentraxin-3 levels as biomarkers for vulnerable plaques in STEMI: Correlation with SYNTAX and Gensini scores	15
Importance of beta-lactam pharmacokinetics and pharmacodynamics on the recovery of microbial diversity in the airway of persons with cystic fibrosis	15
Relationship between circulating serum omentin-1 levels and nascent metabolic syndrome in patients with hypertension	15
Unveiling sarcopenia in Sjögren’s syndrome: A hidden comorbidity	15

Bifidobacterium bifidum BGN4 fractions ameliorate palmitic acid-induced hepatocyte ferroptosis by inhibiting SREBP1-CYP2E1 pathway	14
Analysis of risk factors for abdominal aortic calcification in dialysis patients and its influence on long-term recovery	14
Human microglia polarization following infection with the Lyme disease spirochete	14
FK-binding protein 5: Possible relevance to the pathogenesis of metabolic dysfunction and alcohol-associated liver disease	14
EXPRESS: Effect of insulin aspart combined with insulin detemir and metformin on islet function in newly diagnosed type 2 diabetes mellitus	14
2022 Southern Medical Research Conference	14
Yet Another Amyloidosis	13
Combined treatment with ruxolitinib and MK-2206 inhibits ERα activity by inhibiting MAPK signaling in BT474 breast cancer cells	12
Inhaled corticosteroids on mortality in COVID-19: A systematic review and meta-analysis of randomized controlled trials	12
Deferasirox Combination with Eltrombopag Shows Anti-Myelodysplastic Syndrome Effects by Enhancing iron Deprivation–Related Apoptosis	12
Response to: Faculty should be cautiously optimistic about the role of generative AI in medical education	12
Introduction of 2024 International Conference on Advances in Biological Science and Technology, September 28-30, 2024, Online Video Conference	12
Trends and Demographic Patterns in Biologic and Corticosteroid Prescriptions for Inflammatory Bowel Disease: Findings from Electronic Medical Records, 2011–2020	12
MEF2A restrains cisplatin resistance in gastric cancer cells by modulating NFKBIA/NF-κB signaling pathway	12
An innovative approach to comprehensive communication skills training for residents: A resident-led communication curriculum	12
Patient perception of voxelotor treatment benefit in sickle cell disease	11
Utility of Serum Neuropilin-1 and Angiopoietin-2 as Markers of Hepatocellular Carcinoma	11
Cancer Immunotherapy in Adult Patients with HIV	11
Bronchodilatory Effect of Higenamine as Antiallergic Asthma Treatment	11
Dynamic Albumin Values as Clinical Surrogate for Covid-19 Therapeutics	10
Latin Americans and US Hispanics show Differences in IBD Phenotype: A Systematic Review with Meta-Analysis	10
Predictors of misperceptions, risk perceptions, and personal risk perceptions about COVID-19 by country, education and income	10
Historical view of medical Spanish instruction in a medical school at the US–Mexico border region	10
Clinical characteristics, prognostic factors, and outcomes of ventricular septal rupture in patients with acute myocardial infarction	10
Serum liver enzymes and metabolic syndrome from the Rafsanjan Cohort Study	9
Beyond age and family history: Symptoms as predictors in colorectal cancer screening	9
LECT-2 Amyloidosis: What do we Know?	9
COVID-19 in the intensive care unit: Unmasking the critical factors impacting patient survival	9
Epidemiology, diagnosis, and management of cardiac amyloidosis	9
Mitochondria Signaling Pathways in Allergic Asthma	9
The role of immune activation and antigen persistence in acute and long COVID	9
Large language model content detectors: Effects of human editing and ChatGPT mimicking individual style—A preliminary study	8
Current status of novel weight loss interventions	8
Clinical differences in symptomology, characteristics, and risk factors in patients with post-acute sequelae of COVID-19: an experience from a tertiary-care academic center	8
Bleeding Ectopic Varices: Clinical Presentation, Natural History, and Outcomes	8
Metabolic Derangement in Patients with Vitiligo: A Cross-Sectional Study	8
Venous Capacitance and Venous Return in Young Adults with Typical Vasovagal Syncope: A Cross-Sectional Study	8
Evaluation of thiol–disulfide homeostasis and oxidative stress parameters in newborns receiving phototherapy	8
The association of systemic lupus erythematosus with short-term mortality in sepsis: a population-level analysis	8
Comparison of outcome among type 2 vs type 1 myocardial infarction: a systematic review and meta-analysis	8
Network analysis of genes associated with esophageal squamous cell carcinoma progression	8
Study of antibiotic resistance and virulence genes in Escherichia coli isolated from urinary tract infection patients in Tanta University Hospitals	8
Liver fibrosis prediction models in a population of Latina and White women	8
Normal saline vs balanced intravenous fluids in acute ischemic stroke: A retrospective study	8
Peripheral ICOS+CD4 T cell frequency: An indicator for short-term progression in resectable advanced gastric cancer following platinum-based chemotherapy	8
Clinical characteristics and social determinants of health associated with 30-day hospital readmissions of patients with COVID-19	8
Applicant essays and recommendation letters in residency selection:How generative artificial intelligence is changing them	8
Depressive Symptomatology in Adults during the COVID-19 Pandemic	7
Wegovy (Semaglutide): A New Weight Loss Drug for Chronic Weight Management	7
Health insurance prevalence and acute pancreatitis mortality: a cross-sectional analysis	7

Translational science and related disciplines	7
COVID-19’s immuno-pathology and cardiovascular diseases	7
Comparing the Effects of Twice-Daily Exenatide and Insulin on Renal Function in Patients with Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Controlled Trial	7
Association of intermittent versus continuous hemodialysis modalities with mortality in the setting of acute stroke among patients with end-stage renal disease	7
Response to: Applicant essays and recommendation letters in residency selection: How generative artificial intelligence is changing them	7
Autophagy and Cancer Metastasis: A Trojan Horse	7
Expanded hemodialysis: a new concept of renal replacement therapy	7
Management of deep neck infections in adults and importance of clinical and laboratory findings	7
Association between monocyte to high-density lipoprotein-cholesterol ratio and osteoporosis: An analysis of the National Health and Nutrition Examination Survey 2013–2014	7
Effects of non-surgical treatment of chronic periodontitis on insulin resistance and glucose tolerance in subjects without diabetes (PARODIA 2 study)	7
Effect of Bisphosphonate on Hip Fracture in Patients with Osteoporosis or Osteopenia According to age: A Meta-Analysis and Systematic Review	7
Prediction of overall survival after radical gastrectomy using nomograms created by tumor markers	6
Comparing Patient Characteristics and Outcomes in Type 1 versus Type 2 Diabetes with Diabetic Ketoacidosis: A Review and a Propensity-Matched Nationwide Analysis	6
Natriuretic Peptides, Extracellular Volume, and Subclinical Cardiovascular Changes in Chronic Kidney Disease Stages 1–3: A Pilot Study	6
Patterns and seasonality in pediatric referrals for functional somatic symptoms	6
Response to: Correspondence on ‘Prospective Predictive Performance Comparison between Clinical Gestalt and Validated COVID-19 Mortality Scores’ by Meza-Comparán	6
Nasopharyngeal airway-assisted sedation enhances oxygenation and reduces perioperative adverse events in pediatric dental surgery: A comparative clinical study	6
Glucose ingestion does not lower testosterone concentrations in men on testosterone therapy	6
Cholesterol deficiency as a mechanism for autism: A valproic acid model	6
Incidence and Risk Factors for Mucormycosis in Renal Transplant Patients	6
Cannabinoid hyperemesis syndrome: prevalence and management in an era of cannabis legalization	6
EXPRESS: Bispecific T-cell Engagers for Relapsed/Refractory Multiple Myeloma After Solid Organ Transplantation: A Case Series	6
The effect of over- and undertreatment of hypothyroidism on hospitalization outcomes of patients with decompensated heart failure	6
American Federation for Medical Research 2025 Southeastern Regional Meeting	6
Screening for presence of primary Sjogren’s syndrome in patients with autoimmune thyroid diseases	6
Serum Levels of IL-37 and Correlation with Inflammatory Cytokines and Clinical Outcomes in Patients with Coronary Artery Disease	5
Assessing the causal relationship between obesity and hypothyroidism using Mendelian randomization	5
In-vivo Skeletal Muscle Mitochondrial Function in Klinefelter Syndrome	5
Cohen's d and Physicians’ Opinion on Effect Size: A Questionnaire on Anemia Treatment	5
Epidemiological and Clinical Characteristics of Non-Severe and Severe Pediatric and Adult COVID-19 Patients across Different Geographical Regions in the Early Phase of Pandemic: A Systematic Review an	5
Direct-to-patient telemedicine: Expanding access to regional pediatric specialty care	5
Retrospective Evaluation of Patients with and without 14-Day Readmissions following Hospitalization for COVID-19	5
Effects of prehabilitation resistance training in mild to moderate clinically frail patients awaiting coronary artery bypass graft surgery	5
A novel predictive model based on pericarotid adipose tissue and lumen stenosis for stroke risk in patients with asymptomatic carotid stenosis	5
Implementation of telepsychiatry in an urban pediatric satellite emergency department	5
Correspondence on “Prognostic significance of complement factors in severely ill patients with COVID-19”	5
Evaluating Trends In Rumination Syndrome: A Retrospective Analysis	5
Author Index	5
Rapid qPCR-based quantitative immune cell phenotyping in mouse tissues	5
Association of exposure to nonpersistent endocrine disruptors with sex hormones and metabolic health in US females	5
Dual-specificity phosphatase 8 (DUSP8) induces drug resistance in breast cancer by regulating MAPK pathways	5
Specific Changes of Erythroid Regulators and Hepcidin in Patients Infected by SARS-COV-2	4
Semaglutide 2.4 Mg: The Latest GLP-1RA Approved for Obesity	4
Association between Blood Carboxyhemoglobin Level and Bronchopulmonary Dysplasia in Extremely Low Birthweight Infants	4
Spexin as a potential biomarker for autoimmune inflammation in Graves’ disease	4
Protective effect of Shenfu on gut epithelium in a porcine model of hemorrhagic shock	4
Butylphthalide protects against ischemia-reperfusion injury in rats via reducing neuron ferroptosis and oxidative stress	4
Hematological ratios in coronavirus disease 2019 patients with and without invasive mechanical ventilation	4
AFMR Southeastern Regional Meeting Supplement	4
Trends of Sources of Clinical Research Funding from 1990 to 2020: A Meta-Epidemiological Study	4
A new therapeutic perspective: Erastin inhibits tumor progression by driving ferroptosis in myelodysplastic syndromes	4
Reflections on my presidency of American Federation of Medical Research (AFMR)	4
Abstracts	4
Treatment and Outcomes among Patients ≥85 Years Hospitalized with Community-Acquired Pneumonia	4
Strengthening research capacity of early-mid career researchers: Implementation and evaluation of the Excellence in Non-COmmunicable disease REsearch (ENCORE) program	4
Polymorphism of Angiotensin-Converting Enzyme 2 Gene ( rs 2285666 ) and its susceptibility to COVID-19 infection and severity of the disea	4
Construction and validation of an autophagy-related long non-coding RNA signature to predict the prognosis of kidney renal papillary cell carcinoma	4
Correspondence on ‘Role of AMPK/mTOR-independent autophagy in clear cell renal cell carcinoma’ by Radovanovic et al	4
The incidence and characteristics of giant cell arteritis in Hispanics and the associated outcomes of ischemic ocular events and stroke	4
Public health initiatives: Addressing social vulnerability in research and practice	4
Pharmacokinetic advantages of lipophilic statins over rosuvastatin in COVID-19 management	4
Comparison of clinicopathological characteristics and response to neoadjuvant systemic therapy in patients with HER2-low-positive and HER2-zero breast cancer	4
Correlation of Rate of Serum Albumin Decline with other Acute Phase Reactants and Effect of Current Treatment Options on Serum Albumin Level in Covid-19	4
GANT61, an inhibitor of Gli1, inhibits the proliferation and migration of hepatocellular carcinoma cells	4
Ambulatory Cardiology Telemedicine: A Large Academic Pediatric Center Experience	4
Overview of Severe Asthma, with Emphasis on Pediatric Patients: A Review for Practitioners	4
Study of role of melanoma-associated antigen D1 (MAGE-D1) in hepatocellular carcinoma	4
Understanding the association between admission source and in-hospital delirium: A cross-sectional study	4
Challenging biological samples and strategies for DNA extraction	4
Outcomes of beta-blocker therapy in methamphetamine users with cardiovascular conditions	4
Timing of convalescent plasma administration and 28-day mortality in COVID-19 pneumonia	4
Single-center outcomes of artificial intelligence in management of pulmonary embolism and pulmonary embolism response team activation	4
Severe COVID-19-associated hyperinflammatory syndrome versus classic hemophagocytic lymphohistiocytosis: similarities, differences, and the way forward	4
Association between nonalcoholic fatty liver disease and atrial fibrillation and other clinical outcomes: a meta-analysis	4
Effect of intramuscular depot betamethasone injection in patients with fibromyalgia and elevated C-reactive protein levels	4
Corrigendum to “GDF11 Level and Its Effect on Prognosis in Patients with Acute Myeloid Leukemia”	4
Prevalence, outcomes, and complications of vitamin D deficiency among patients with multiple myeloma: Nationwide burden of disease	4
Assessment of serum level of galectin-9 in systemic lupus erythematosus patients in Tanta University hospitals, case-control research	4
Clinical predictions of COVID-19 patients using deep stacking neural networks	4
State of the art: Alternative overlap syndrome—asthma and obstructive sleep apnea	4

N-Terminal Pro-Brain Natriuretic Peptide is an Independent Predictor of Mortality in Patients with Sepsis	4
Sequential administration of pemetrexed and cisplatin reprograms tumor immune microenvironment and potentiates PD-1/PD-L1 treatment in a lung cancer model	4