Seminars in Cell & Developmental Biology

Article	Citations
Editorial Board/Publication Information	554
Outside Front Cover	184
Alzheimer’s Disease: Effects on brain circuits and synapses	177
In memoriam: Huib Ovaa, the brain behind the formula (18/12/1973–19/05/2020)	172
Removal of cellular protrusions	150
Plasma membrane repair empowers the necrotic survivors as innate immune modulators	144
Approximating the living	80
Balance between the cell viability and death in 3D	76
Dissecting the neurobiology of linguistic disorganisation and impoverishment in schizophrenia	75
Epitranscriptomic regulation of cognitive development and decline	73
Fundamentals of bone vasculature: Specialization, interactions and functions	72
Thrombospondin-1 in vascular development, vascular function, and vascular disease	70
Somite development and regionalisation of the vertebral axial skeleton	66
Editorial	64
Rearrangement of co-cultured cellular systems: Biological and physical aspects	63
Outside Front Cover	62
The tubulin code: Empowering microtubules	61
Outside Front Cover	60
Understanding the interplay of membrane trafficking, cell surface mechanics, and stem cell differentiation	59
Editorial Board/Publication Information	58
Editorial Board/Publication Information	58
Planar cell polarity (PCP) proteins support spermatogenesis through cytoskeletal organization in the testis	57
Start early and pack light: Collaborative adventures in theory and experiment	57
Antibodies in the intracellular domain	57
Mechanisms of formation and functions of the early embryonic cavities	55

Chromoanagenesis, the mechanisms of a genomic chaos	55
All eggs in one basket: How potyvirus infection is controlled at a single cap-independent translation event	54
Natural variation in metabolism of the Calvin-Benson cycle	53
RNA Polymerases I and III in development and disease	51
Modelling the dynamics of mammalian gut homeostasis	50
Parallels between the extracellular matrix roles in developmental biology and cancer biology	50
Evolution of the insect Hox gene cluster: Comparative analysis across 243 species	49
Mechanical mechanisms of morphogenesis as potential substrates for evolutionary change	48
The C. elegans anchor cell: A model to elucidate mechanisms underlying invasion through basement membrane	47
The emerging roles of the cytoskeleton in intestinal epithelium homeostasis	47
Snapshots from within the cell: Novel trafficking and non trafficking functions of Snap29 during tissue morphogenesis	46
Outside Front Cover	46
Membrane compartmentalisation of the ubiquitin system	46
rDNA transcription, replication and stability in Saccharomyces cerevisiae	46
Editorial Board/Publication Information	46
An emerging role for the endoplasmic reticulum in stress granule biogenesis	45
Editorial Board/Publication Information	45
Carnegie in 4D? Stem-cell-based models of human embryo development	44
Out with the old, in with the new: Meiotic driving of sex chromosome evolution	43
Stem Leydig cells: Current research and future prospects of regenerative medicine of male reproductive health	42
The developmental and evolutionary origins of cellular pluripotency in the vertebrate neural crest	42
Sertoli cells as key drivers of testis function	42
The ever-diversifying landscape of intra-genomic conflict	40
The tubulin code in platelet biogenesis.	39
Recent advances in understanding cell types during human gastrulation	39
Genome instability from nuclear catastrophe and DNA damage	38
C. elegans: An elegant experimental system for the study of cilia biology	37
Outside Front Cover	37
Establishing and maintaining Hox profiles during spinal cord development	37
Deep conservation and co-option of programmed cell death facilitates evolution of alternative phenotypes at multiple biological levels	37
MicroRNA-1: Diverse role of a small player in multiple cancers	37
Thrombospondin proteins – Versatile extracellular proteins with multiple biological functions	37
Self-organized collective cell behaviors as design principles for synthetic developmental biology	36
Molecular cell types as functional units of the efferent vagus nerve	36
Recent insights into atrial chamber formation	35
S-cone circuits in the primate retina for non-image-forming vision	35
Epithelial to mesenchymal transition during mammalian neural crest cell delamination	35
Hox, homology, and parsimony: An organismal perspective	34
Editorial Board/Publication Information	33
The Calvin Benson cycle in bacteria: New insights from systems biology	33
Engineered implementations of spatial computation in biological systems	33
Hydrostatic pressure as a driver of cell and tissue morphogenesis	33
The Drivers of Diversity: Integrated genetic and hormonal cues regulate neural diversity	33
Outside Front Cover	32
Outside Front Cover	32
Breaking the vicious circle: Extrachromosomal circular DNA as an emerging player in tumour evolution	32
Kidney development to kidney organoids and back again	31
Genetically encoded intrabodies as high-precision tools to visualize and manipulate neuronal function	31
Nuclear organization by satellite DNA, SAF-A/hnRNPU and matrix attachment regions	30
Towards a molecular understanding of the 5′TOP motif in regulating translation of ribosomal mRNAs	30

The mechanics of shaping organs in plants	30
The HERC proteins and the nervous system	30
Maternal selection of human embryos in early gestation: Insights from recurrent miscarriage	29
Dynamic regulation of ribosome levels and translation during development	29
Apoptotic signaling: Beyond cell death	29
Tissue interplay during morphogenesis	29
Viral manipulation of host cell gene expression	28
Human placental development and function	28
Recent advancement in the spatial immuno-oncology	28
High-resolution omics of vascular ageing and inflammatory pathways in neurodegeneration	28
Developmental energetics: Energy expenditure, budgets and metabolism during animal embryogenesis	28
Collective cell migration across scales: A systems perspective	28
Novel concepts of molecular mechanisms in spermatogenesis	28
Direct cardiac reprogramming comes of age: Recent advance and remaining challenges	28
Evolvability in vertebrate segmentation	28
Strategic use of organoids and organs-on-chip as biomimetic tools	27
How to get the most out of your cancer spatial transcriptomics data	27
Neuronal identity and cognitive control dynamics in the PFC	27
Evolution, structure and function of divergent macroH2A1 splice isoforms	27
Imaging spatiotemporal translation regulation in vivo	27
Direct reprogramming as a route to cardiac repair	27
Dermal extracellular matrix molecules in skin development, homeostasis, wound regeneration and diseases	27
Neuronal ensembles in memory processes	27
TALE transcription factors: Cofactors no more	27
A near death experience: The secret stem cell life of caspase-3	26
Muscle-derived factors influencing bone metabolism	26
Ubiquitin and Legionella: From bench to bedside	26
Outside Front Cover	26
Epigenetics of inflammation in hypothalamus pituitary gonadal and neuroendocrine disorders	25
Moving through the crowd. Where are we at understanding physiological axon growth?	25
Assigning function to SNPs: Considerations when interpreting genetic variation	25
Editorial Board/Publication Information	25
Charting the cardiac landscape: Advances in spatial transcriptomics for heart biology	25
Mitochondrial Apoptotic Signaling Involvement in Remodeling During Myogenesis and Skeletal Muscle Atrophy	25
Cover image of cell death and resilience in health and disease	25
Recent advances in understanding microRNA function and regulation in C. elegans	25
C. elegans as a model for health and disease	25
Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly	25
Stress granules and P-bodies – New ideas and experimental models worth exploring	25
Cellular and tissue crosstalk in musculoskeletal development	25
Unravelling the mysteries of human embryogenesis	24
Pinpointing the locus of GABAergic vulnerability in Alzheimer’s disease	24
Force: A messenger of axon outgrowth	24
Towards deciphering the bone marrow microenvironment with spatial multi-omics	24
Epigenetic regulation of inflammation	24
Timing without coding: How do long non-coding RNAs regulate circadian rhythms?	24
MicroRNAs: Key modulators of inflammation-associated diseases	24
Editorial Board/Publication Information	24
Mitochondrial-derived vesicles in skeletal muscle remodeling and adaptation	24
Dickkopf signaling, beyond Wnt-mediated biology	24
Host plant physiological transformation and microbial population heterogeneity as important determinants of the Soft Rot Pectobacteriaceae–plant interactions	23
Homeodomain complex formation and biomolecular condensates in Hox gene regulation	23
Outside Front Cover	23
Developmental heterogeneity of vascular cells: Insights into cellular plasticity in atherosclerosis?	23
Editorial	23
The microbiome: A heritable contributor to bone morphology?	23
Editorial on “Vascular cell fate in health and disease”	23
Outside Front Cover	23
Editorial Board/Publication Information	23
WNT5B in cellular signaling pathways	23
Inflammation in Hernia and the epigenetic control	23
Regulation of organelle size and organization during development	22
Temporal control of neuronal wiring	22
Nuclear envelope assembly and dynamics during development	22
The interplay of tissue mechanics and gene regulatory networks in the evolution of morphogenesis	22
The implications of physiological biomolecular condensates in amyotrophic lateral sclerosis	22
Novel approaches to increase synaptic resilience as potential treatments for Alzheimer’s disease	22
Mitochondrial recovery by the UPRmt: Insights from C. elegans	22
Emerging roles of DNA repair factors in the stability of centromeres	21
Editorial Board/Publication Information	21
Biomechanical models and mechanisms of cellular morphogenesis and cerebral cortical expansion and folding	21
Start-Shape-Stop: Cell communication mechanisms controlling organ size	21
Gradients, waves and nematics: quantitative perspectives on regeneration	21
“Transfer” of power: The intersection of DNA virus infection and tRNA biology	21
Editorial Board/Publication Information	21
Hox gene functions in the C. elegans nervous system: From early patterning to maintenance of neuronal identity	21
Mechanics of neural tube morphogenesis	21
Thrombospondin-1 in drug activity and tumor response to therapies	21
Transcription-coupled H3.3 recycling: A link with chromatin states	21
Circadian NAD(P)(H) cycles in cell metabolism	21

P-body-like condensates in the germline	21
The molecular clockwork of mammalian cells	20
The influence of epigenetics and inflammation on cardiometabolic risks	20
Microtubule and auditory function – an underestimated connection	20
Thrombospondins modulate cell function and tissue structure in the skeleton	20
Collective sperm movement in mammalian reproductive tracts	20
Histone variant-specific post-translational modifications	20
Sex differences in daily timekeeping and circadian clock circuits	20
Time to see: How temporal identity factors specify the developing mammalian retina	20
Biochemical mechanisms of period control within the mammalian circadian clock	19
Nuclear size and shape control	19
Capturing ovarian dynamics through spatial profiling of the mechano-microenvironment	19
miRNAs as novel immunoregulators in cancer	19
In vivo reprogramming as a new approach to cardiac regenerative therapy	19
Deciphering the interplay between autophagy and polarity in epithelial tubulogenesis	19
Gastrulation morphogenesis in synthetic systems	19
Special issue: “Novel functions of programmed cell death in development: Current status and future challenges”	19
Reframing research on evolutionary novelty and co-option: Character identity mechanisms versus deep homology	19
The why and how of sleep-dependent synaptic down-selection	19
The dynamics along the biointerface between the epithelial and cancer mesenchymal cells: Modeling consideration	18
Cardiac specification during gastrulation – The Yellow Brick Road leading to Tinman	18
For Special Issue: Tissue size and shape	18
Editorial Board/Publication Information	18
Multi-layered transcriptional control of cranial neural crest development	18
Interaction between bone and immune cells: Implications for postmenopausal osteoporosis	18
Collective mitochondrial dynamics resolve conflicting cellular tensions: From plants to general principles	18
MicroRNAs in shaping the resolution phase of inflammation	18
Editorial Board/Publication Information	18
Every refuge has its price: Ostreobium as a model for understanding how algae can live in rock and stay in business	18
Lessons for cardiac regeneration from non-mammalian model organisms	18
The wonderful wanderer	18
Outside Front Cover	18
Molecular mechanisms regulating the spatial configuration of neurites	18
Editorial Board/Publication Information	18
Dynamical systems of fate and form in development	17
A genome-wide perspective of the maternal mRNA translation program during oocyte development	17
Outside Front Cover	17
Outside Front Cover	17
Alliances of the gut and bone axis	17
Outside Front Cover	17
Mechanistic origins of diverse genome rearrangements in cancer	17
Coping with uncertainty: Challenges for robust pattern formation in dynamical tissues	17
Mesoderm differentiation in vertebrate development and regenerative medicine	17
Outside Front Cover	17
The impact of antidepressants on human neurodevelopment: Brain organoids as experimental tools	17
Impairments of glutamatergic synaptic transmission in Alzheimer’s disease	17
On the evolutionary origins and regionalization of the neural crest	17
Outside Front Cover	17
Editorial Board/Publication Information	17
Cilia-derived vesicles: An ancient route for intercellular communication	16
Regulation and integration of membrane transport in marine diatoms	16
Human epiblast lumenogenesis: From a cell aggregate to a lumenal cyst	16
Presubiculum principal cells are preserved from degeneration in knock-in APP/TAU mouse models of Alzheimer’s disease	16
Editorial Board/Publication Information	16
Ciliary signaling in stem cells in health and disease: Hedgehog pathway and beyond	16
Generative models of morphogenesis in developmental biology	16
Principles and functions of pericentromeric satellite DNA clustering into chromocenters	16
Cellular protrusions in 3D: Orchestrating early mouse embryogenesis	16
Distributed computing inspired by biology	16
Directing with restraint: Mechanisms of protrusion restriction in collective cell migrations	16
Untangling the relationship between developmental and evolutionary integration	16
Fatal attraction: How Phytophthora zoospores find their host	16
Editorial Board/Publication Information	15
Bridging the gap between non-canonical and canonical Wnt signaling through Vangl2	15
Sexual conflict drive in the rapid evolution of new gametogenesis genes	15
Regulating metabolism to shape immune function: Lessons from Drosophila	15
Force of change: How biomechanical cues drive endothelial plasticity and morphogenesis	15
Vagal sensory pathway for the gut-brain communication	15
Targeted protein degradation using intracellular antibodies and its application to neurodegenerative disease	15
Outside Front Cover	15
Outside Front Cover	15
Dynamic interplay between human alpha-satellite DNA structure and centromere functions	15
Viscoelasticity during development: What is it? and why should you care?	15
Genomic stability and epigenetic inheritance in holocentric Caenorhabditis elegans and insects	15
An emergent Wnt5a/YAP/TAZ regulatory circuit and its possible role in cancer	15
Genetic conflicts in budding yeast: The 2μ plasmid as a model selfish element	15
Colorectal keratins: Integrating nutrition, metabolism and colorectal health	14
Regulation of cell signaling pathways by circular RNAs and microRNAs in different cancers: Spotlight on Wnt/β-catenin, JAK/STAT, TGF/SMAD, SHH/GLI, NOTCH and Hippo pathways	14
Organoids as a novel tool in modelling infectious diseases	14
Chemical biology tools to study Deubiquitinases and Ubl proteases	14
Better late than never: A unique strategy for late gene transcription in the beta- and gammaherpesviruses	14
Editorial Board/Publication Information	14
Orchestration of tissue shape changes and gene expression patterns in development	14
Emerging roles for microproteins as critical regulators of endoplasmic reticulum function and cellular homeostasis	14
Circuit mechanisms for cortical plasticity and learning	14
Cell biology of the gut	13
The multiple roles of enteric glial cells in intestinal homeostasis and regeneration	13
Why cellular computations challenge our design principles	13
An organismal understanding of C. elegans innate immune responses, from pathogen recognition to multigenerational resistance	13
Editorial Board/Publication Information	13
The mechanics behind the Drosophila egg	13
Editorial Board/Publication Information	13
Direct cardiac reprogramming: A new frontier in heart regeneration	13
Polycystic ovary syndrome and related inflammation in radiomics; relationship with patient outcome	13
Ribosome homeostasis	13