Seminars in Cell & Developmental Biology

Article	Citations
TGF-β1 – A truly transforming growth factor in fibrosis and immunity	261
Interaction between bone and immune cells: Implications for postmenopausal osteoporosis	222
Spindle assembly checkpoint activation and silencing at kinetochores	124
The substrate repertoire of γ-secretase/presenilin	117
Non-canonical (non-SMAD2/3) TGF-β signaling in fibrosis: Mechanisms and targets	95
Hepatic lipid droplet homeostasis and fatty liver disease	94
Motile cilia and airway disease	86
Filopodia and their links with membrane traffic and cell adhesion	84
Iron in immune cell function and host defense	84
Direct trafficking pathways from the Golgi apparatus to the plasma membrane	84
Revisiting remyelination: Towards a consensus on the regeneration of CNS myelin	83
Mammalian cell cycle cyclins	80
GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer’s disease	78
Origin and evolution of gibberellin signaling and metabolism in plants	78
Microglia and lipids: how metabolism controls brain innate immunity	77
Evolution and functional diversification of FLOWERING LOCUS T/TERMINAL FLOWER 1 family genes in plants	74
Magnesium and inflammation: Advances and perspectives	70
Mechanisms regulating myoblast fusion: A multilevel interplay	66
Senotherapeutics: Targeting senescence in idiopathic pulmonary fibrosis	65
Towards a structural understanding of the remodeling of the actin cytoskeleton	62
Primary cilia biogenesis and associated retinal ciliopathies	60
Lipid droplets in plants and algae: Distribution, formation, turnover and function	60
LC3-associated phagocytosis - The highway to hell for phagocytosed microbes	59
Transcriptional regulation of multiciliated cell differentiation	59
Developmental and regenerative paradigms of cilia regulated hedgehog signaling	58

Mitotic chromosomes	58
Dermal extracellular matrix molecules in skin development, homeostasis, wound regeneration and diseases	57
Human placental development and function	56
Aluminium adjuvants in vaccines – A way to modulate the immune response	56
Sertoli cells as key drivers of testis function	55
Tracing insights into de novo lipogenesis in liver and adipose tissues	55
Synovial fibroblasts and articular tissue remodelling: Role and mechanisms	52
Autophagy in intracellular bacterial infection	52
Endothelium-mediated contributions to fibrosis	51
Intraflagellar transport trains and motors: Insights from structure	50
Macrophage-mediated inflammation in diabetic wound repair	50
On the biosynthesis and evolution of apocarotenoid plant growth regulators	50
The molecular basis of mammary gland development and epithelial differentiation	48
Metabolic regulation of calcium signaling in beta cells	48
Visual adaptations of diurnal and nocturnal raptors	47
Lipid droplet biogenesis: A mystery “unmixing”?	46
Human centrosome organization and function in interphase and mitosis	46
Human and mouse skeletal muscle stem and progenitor cells in health and disease	46
Contribution of the Presenilins in the cell biology, structure and function of γ-secretase	45
RIPK protein kinase family: Atypical lives of typical kinases	44
Mechanisms of protein targeting to lipid droplets: A unified cell biological and biophysical perspective	44
Role of autophagy during plant-virus interactions	44
Manipulation of autophagy by (+) RNA viruses	44
Lipid metabolism in astrocytic structure and function	42
RIP-roaring inflammation: RIPK1 and RIPK3 driven NLRP3 inflammasome activation and autoinflammatory disease	42
A fork in the road: Where homologous recombination and stalled replication fork protection part ways	42
A centralized communication network: Recent insights into the role of the cancer associated fibroblast in the development of drug resistance in tumors	41
Life-long oligodendrocyte development and plasticity	41
Cilia signaling and obesity	40
Pancreatic α-cells – The unsung heroes in islet function	40
Macrophage regulation of angiogenesis in health and disease	39
Lipids in regulating oligodendrocyte structure and function	39
Kinetochore assembly throughout the cell cycle	39
The biology of lipid droplet-bound mitochondria	39
Aging: All roads lead to mitochondria	39
The exceptional diversity of visual adaptations in deep-sea teleost fishes	39
Fundamentals of bone vasculature: Specialization, interactions and functions	39
Nucleolar stress: From development to cancer	37
Right, left and cilia: How asymmetry is established	37
RAD51: Beyond the break	37
Role of Notch signaling in neurovascular aging and Alzheimer’s disease	37
Crossroads in the evolution of plant specialized metabolism	37
Mechanisms of neurodegeneration — Insights from familial Alzheimer’s disease	36
Roles of CDK/Cyclin complexes in transcription and pre-mRNA splicing: Cyclins L and CDK11 at the cross-roads of cell cycle and regulation of gene expression	36
Lipid droplets, bioenergetic fluxes, and metabolic flexibility	36
Inflammation during post-injury skeletal muscle regeneration	36
Contributions of alternative splicing to muscle type development and function	35
Cilia and polycystic kidney disease	35
Visual system diversity in coral reef fishes	35
Aging biomarkers and the brain	34

Noradrenaline in the aging brain: Promoting cognitive reserve or accelerating Alzheimer's disease?	34
Unraveling the complexity of γ-secretase	33
Maternal selection of human embryos in early gestation: Insights from recurrent miscarriage	32
Selenoproteins as regulators of T cell proliferation, differentiation, and metabolism	32
SUMO-SIM interactions: From structure to biological functions	31
Control of the chromatin response to DNA damage: Histone proteins pull the strings	31
Cilia, neural development and disease	31
Coming of age in the frontal cortex: The role of puberty in cortical maturation	31
Multigenerational epigenetic inheritance: Transmitting information across generations	31
The retinal basis of vision in chicken	31
The adverse impact of cadmium on immune function and lung host defense	30
Perisynaptic schwann cells - The multitasking cells at the developing neuromuscular junctions	30
Chromoanagenesis, the mechanisms of a genomic chaos	30
Cellular complexity in brain organoids: Current progress and unsolved issues	30
From model organism to application: Bacteria-induced growth and development of the green seaweed Ulva and the potential of microbe leveraging in algal aquaculture	30
Successive cleavage of β-amyloid precursor protein by γ-secretase	30
Comparative mammary gland postnatal development and tumourigenesis in the sheep, cow, cat and rabbit: Exploring the menagerie	29
Nuclear actin dynamics in gene expression and genome organization	29
Osteoclast formation at the bone marrow/bone surface interface: Importance of structural elements, matrix, and intercellular communication	29
The many implications of actin filament helicity	29
Human CtIP: A ‘double agent’ in DNA repair and tumorigenesis	29
Ciliogenesis membrane dynamics and organization	29
Making choices: DNA replication fork recovery mechanisms	29
Prolactin: A hormone with diverse functions from mammary gland development to cancer metastasis	28
There and back again: An evolutionary perspective on long-distance coordination of plant growth and development	28
Synapse pathology in Alzheimer’s disease	28
DNA double-strand break repair: Putting zinc fingers on the sore spot	28
Therapeutic strategies for miRNA delivery to reduce hepatocellular carcinoma	28
Regulation of actin isoforms in cellular and developmental processes	28
RIPK2 NODs to XIAP and IBD	28
On being the right shape: Roles for motile cilia and cerebrospinal fluid flow in body and spine morphology	27
Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases	27
A direct look at the dysfunction and pathology of the β cells in human type 2 diabetes	27
The diverse roles of RIP kinases in host-pathogen interactions	27
Novel insights into the coupling of osteoclasts and resorption to bone formation	27
Intrinsic and extrinsic regulators of oligodendrocyte progenitor proliferation and differentiation	26
Synaptic modifications in learning and memory – A dendritic spine story	26
Role of cilia in the pathogenesis of congenital heart disease	26
Dickkopf signaling, beyond Wnt-mediated biology	26
25 years of research put RIPK1 in the clinic	26
Regulation of mammalian spermatogenesis by miRNAs	26
Embryonic mammary gland development	26
Functions of TopBP1 in preserving genome integrity during mitosis	26
Sleep timing and the circadian clock in mammals: Past, present and the road ahead	25
Modelling neurodegenerative disease using brain organoids	25
Substrate recognition by TRIM and TRIM-like proteins in innate immunity	25
The role of lipids in the central nervous system and their pathological implications in amyotrophic lateral sclerosis	24
Crossing boundaries: Interplay between the immune system and oligodendrocyte lineage cells	24
The evolution of cytokinin signaling and its role in development before Angiosperms	24
Transgenerational programming of nephron deficits and hypertension	24
A frog’s eye view: Foundational revelations and future promises	24
Modeling neurological disorders using brain organoids	24
Myogenesis control by SIX transcriptional complexes	24
Microfluidic organoids-on-a-chip: The future of human models	23
The why and how of sleep-dependent synaptic down-selection	23
Stem Leydig cells: Current research and future prospects of regenerative medicine of male reproductive health	23
Oligodendrogenesis and myelination regulate cortical development, plasticity and circuit function	23
Hydrostatic pressure as a driver of cell and tissue morphogenesis	23
Heart organoids and tissue models for modeling development and disease	23
Muscle development : a view from adult myogenesis in Drosophila	23
Genome (in)stability at tandem repeats	23
Integrated stress response in hepatitis C promotes Nrf2-related chaperone-mediated autophagy: A novel mechanism for host-microbe survival and HCC development in liver cirrhosis	23
Endoplasmic Reticulum Protein Quality Control in β Cells	22
A classical revival: Human satellite DNAs enter the genomics era	22
Sex differences in daily timekeeping and circadian clock circuits	22
Bioengineering tissue morphogenesis and function in human neural organoids	22
The roles of microRNAs in regulation of autophagy during bacterial infection	22
Growth and mechanobiology of the tendon-bone enthesis	22
Cellular evasion strategies of Helicobacter pylori in regulating its intracellular fate	22
Tissue cross talks governing limb muscle development and regeneration	22
Patterning and mechanics of somite boundaries in zebrafish embryos	21
Maturation of human pluripotent stem cell derived cardiomyocytes in vitro and in vivo	21
Chromothripsis as a pathogenic driver of multiple myeloma	21
Histone H2A variants: Diversifying chromatin to ensure genome integrity	21
Deconstructing and reconstructing the human brain with regionally specified brain organoids	21
Multifarious roles of lipid droplets in autophagy – Target, product, and what else?	21
Anti-fibrotic mechanisms of exogenously-expanded mesenchymal stromal cells for fibrotic diseases	21
Mechanical regulation of formin-dependent actin polymerization	21
Principles and functions of pericentromeric satellite DNA clustering into chromocenters	21
Developmental regulation of excitatory-inhibitory synaptic balance in the prefrontal cortex during adolescence	20

The homeostatic regulation of ribosome biogenesis	20
MicroRNA regulation of prefrontal cortex development and psychiatric risk in adolescence	20
The centriolar tubulin code	20
New friends for seipin — Implications of seipin partner proteins in the life cycle of lipid droplets	20
Anaphase B: Long-standing models meet new concepts	20
Evolution of CLE peptide signalling	20
The detyrosination/re-tyrosination cycle of tubulin and its role and dysfunction in neurons and cardiomyocytes	20
Regulatory mechanisms of RIPK1 in cell death and inflammation	20
The essence of the engram: Cellular or synaptic?	20
Axes of visual adaptation in the ecologically diverse family Cichlidae	20
Thyroid hormone, gene expression, and Central Nervous System: Where we are	20
Death versus dedifferentiation: The molecular bases of beta cell mass reduction in type 2 diabetes	20
Viral non-coding RNAs: Stealth strategies in the tug-of-war between humans and herpesviruses	20
The dynamics of γ-secretase and its substrates	20
Long non-coding RNAs in antiviral immunity	20
Mammary gland development from a single cell ‘omics view	20
Olfactory modulation of the medial prefrontal cortex circuitry: Implications for social cognition	20
The metaphase spindle at steady state – Mechanism and functions of microtubule poleward flux	19
A unifying model for extrachromosomal circular DNA load in eukaryotic cells	19
Manganese homeostasis at the host-pathogen interface and in the host immune system	19
Nuclear positioning during development: Pushing, pulling and flowing	19
Rationally-based therapeutic disease modification in systemic sclerosis: Novel strategies	19
γ-Secretase inhibitors and modulators: Mechanistic insights into the function and regulation of γ-Secretase	19
Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis	19
Centrosome dysfunction in human diseases	19
Tenascin-C in fibrosis in multiple organs: Translational implications	19
Biogenesis of circular RNAs and their role in cellular and molecular phenotypes of neurological disorders	19
A focus on yeast mating: From pheromone signaling to cell-cell fusion	19
Effect of varicoceles on spermatogenesis	19
Membrane-actin interactions in morphogenesis: Lessons learned from Drosophila cellularization	18
Imaging fetal anatomy	18
Regulating metabolism to shape immune function: Lessons from Drosophila	18
Brain organoids, consciousness, ethics and moral status	18
Cilia and centrosomes: Ultrastructural and mechanical perspectives	18
Vertebrate Wnt5a – At the crossroads of cellular signalling	18
Ubiquitin and Legionella: From bench to bedside	18
Control of cardiomyocyte differentiation timing by intercellular signaling pathways	18
Genome instability from nuclear catastrophe and DNA damage	18
Estrogens and the circadian system	18
Roadblocks and fast tracks: How RNA binding proteins affect the viral RNA journey in the cell	18
Impact of the actin cytoskeleton on cell development and function mediated via tropomyosin isoforms	17
Evolution of holocentric chromosomes: Drivers, diversity, and deterrents	17
The De-, Re-, and trans-differentiation of β-cells: Regulation and function	17
Wiring of higher-order cortical areas: Spatiotemporal development of cortical hierarchy	17
The molecular clockwork of mammalian cells	17
Neuronal filopodia: From stochastic dynamics to robustness of brain morphogenesis	17
A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity	17
Spatial regulation of mTORC1 signalling: Beyond the Rag GTPases	17
MicroRNAs in shaping the resolution phase of inflammation	17
Establishing compartment boundaries in Drosophila wing imaginal discs: An interplay between selector genes, signaling pathways and cell mechanics	17
Lipid profiling of brain tissue and blood after traumatic brain injury	17
Pubertal mammary gland development is a key determinant of adult mammographic density	17
Ubiquitin-mediated mechanisms of translational control	17
Actin-based regulation of ciliogenesis – The long and the short of it	17
Brain-based mechanisms of late-life depression: Implications for novel interventions	17
The multiple functions of hindbrain boundary cells: Tinkering boundaries?	17
Function of peripheral nerves in the development and healing of tendon and bone	17
Vision in sharks and rays: Opsin diversity and colour vision	17
Copper in infectious disease: Using both sides of the penny	16
Less-well known functions of cyclin/CDK complexes	16
MicroRNAs: Harbingers and shapers of periodontal inflammation	16
Dissecting the neurobiology of linguistic disorganisation and impoverishment in schizophrenia	16
Mechanics and self-organization in tissue development	16
Role of cyclins and cyclin-dependent kinases in pluripotent stem cells and their potential as a therapeutic target	16
The impact of ageing and sex on sympathetic neurocirculatory regulation	15
RIPK1 ubiquitination: Evidence, correlations and the undefined	15
The lifecycle of the neuronal microtubule transport machinery	15
Alliances of the gut and bone axis	15
Neuronal ensembles in memory processes	15
Genome diversity and instability in human germ cells and preimplantation embryos	15
Nuclear size and shape control	15
The future of cerebral organoids in drug discovery	15
RNA Polymerases I and III in development and disease	15
The interplay of autophagy and enterovirus	15
Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly	15
The m6A-epitranscriptome in brain plasticity, learning and memory	15
Transcription blockage by DNA damage in nucleotide excision repair-related neurological dysfunctions	15
Centrosome structure and biogenesis: Variations on a theme?	15
Endothelial cell mechanics and blood flow forces in vascular morphogenesis	15
Cell sorting and morphogenesis in early Drosophila embryos	15
Tissue segregation in the early vertebrate embryo	15
Directing with restraint: Mechanisms of protrusion restriction in collective cell migrations	15
Impairments of glutamatergic synaptic transmission in Alzheimer’s disease	15
Mechanistic origins of diverse genome rearrangements in cancer	15
Chatterboxes: the structural and functional diversity of cyclins	15