International Journal of Toxicology

Papers
(The median citation count of International Journal of Toxicology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Safety Assessment of Adenosine as Used in Cosmetics19
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats17
Isopropyl Lanolate15
Mink Oil12
Effect of Chronic Consumption of Fluoridated Water on Sciatic Nerve Conduction Velocity in Male Wistar Rats12
In Utero Exposure to Di-n-butyl Phthalate Causes Modulation in Neurotransmitter System of Wistar Rats: A Multigenerational Assessment10
Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro9
Editor’s Response to Jorge A. García-Valenzuela and Martha R. Baez-Gaxiola8
Sodium α-Olefin Sulfonates8
Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics8
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics8
A Characterization of the Nonclinical Pharmacology and Toxicology of Aficamten, a Reversible Allosteric Inhibitor of Cardiac Myosin8
I Wish I Had Known That! Impactful Guidance and Perspectives for a Fulfilling Career in Toxicology8
Editor’s Note7
Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics7
The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development7
Recent Advances in Analytical Techniques for Antidepressants Determination in Complex Biological Matrices: A Review7
Glycol Stearate and Glycol Stearate SE7
In Silico Human Cardiomyocyte Action Potential Modeling: Exploring Ion Channel Input Combinations7
Model Characterization: Total Body Irradiation or Busulfan for Conditioning in Human Cell Therapy Toxicology and Tumorigenicity Studies using NOD/SCID/IL2Rγnull (NSG) Mice6
Safety Assessment of Hydrogen Peroxide as Used in Cosmetics6
In vitro Safety Assessment of Extracts and Compounds From Plants as Sunscreen Ingredients6
Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species6
Novel Finding of Urinary Erythropoietin as an Early Biomarker of Cisplatin-Induced Nephrotoxicity6
Amyl Acetate and Isoamyl Acetate6
Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics6
Safety Assessment of Apple-Derived Ingredients as Used in Cosmetics6
Dose Range-Finding Toxicity Study in Rats With Recombinant Human Lactoferrin Produced in Komagataella phaffii6
Hepatitis A Virus Infection in Cynomolgus Monkeys Confounds the Safety Evaluation of a Drug Candidate6
A Commentary on Fasting of Nonclinical Research Animals6
Amended Safety Assessment of Acid Violet 43 as Used in Cosmetics6
Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics6
Lard and Lard-Derived Ingredients5
Safety Assessment of Methylxanthines as Used in Cosmetics5
Polyamino Sugar Condensate5
Assessment of Global DNA Methylation in SH-SY5Y Cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam5
Toxicology Certification: The Need, the Value, and an Evolving Landscape5
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats5
Book Review: Reproductive and Developmental Toxicology Third Edition4
Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex4
Amended Safety Assessment of Methylchloroisothiazolinone and Methylisothiazolinone as Used in Cosmetics4
A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults4
Safety Assessment of Keratin and Keratin-Derived Ingredients as Used in Cosmetics4
Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity, Drug Abuse Liability, and Pediatric Safety4
Comparative Analyses of the Influences of Vehicles on Selected Biological Parameters Following Single-Dose Oral Administration in Sprague-Dawley Rats4
Thank you to our ad hoc reviewers!4
Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review4
AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration4
Non-Human Primate Husbandry and Impact on Non-Human Primates Health: Outcomes From an IQ DruSafe/3RS Industrial Benchmark Survey4
Effects of Solvent Dimethyl Sulfoxide Invites a Rethink of Its Application in Amyloid Beta Cytotoxicity4
Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines4
Book Review: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals4
Chromium [Cr(VI)] Exposure Causes Cytotoxicity of Human Bronchial Epithelial Cells (16-HBE) and Proteomic Alterations3
Shp2 in Alveolar Macrophages Regulates Macrophage I Phenotype in Acute Lung Injury3
Book Review: Haschek and Rousseaux’s Handbook of Toxicologic Pathology3
Effects of Vanadium Inhalation and Sweetened Beverage Ingestion in Mice: Morphological and Biochemical Changes in the Liver3
Exploring the Biological Effects of Polystyrene Nanoplastics on Spermatogenesis: Insights From Transcriptomic Analysis in Mouse Spermatocytes3
Recovery Animals in Toxicology Studies: An Innovation and Quality Consortium Perspective on Best Practices With Case Study Examples3
Book Reviews3
Quaternium-18 and Quaternium-18 Bentonite3
Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers3
NRX-101, a Rapid-Acting Anti-Depressant, Does Not Cause Neurotoxicity Following Ketamine Administration in Preclinical Models3
The Non-Human Primate in Safety Assessment of a Bifunctional Long-Acting Insulin Analogue3
Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics3
Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics3
Final Amended Safety Assessment of Sodium Sulfate as Used in Cosmetics3
Non-Clinical Cell Therapy Development Using the NCG Mouse Model as a Test System3
Safety Assessment of Alkyl Amide MIPA Ingredients as Used in Cosmetics3
Comments on the Risks From Exposure to Denatonium Benzoate (Bitrex®): Denatured Alcohol Disinfection and Pandemic Times2
Eleventh Triennial Toxicology Salary Survey2
Safety Assessment of Citrus Fruit-Derived Ingredients as Used in Cosmetics2
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics2
Evaluation of the Carcinogenic Potential of Enarodustat (JTZ-951), a Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor, in 26-Week Tg.rasH2 Mouse Study and 2-Year Sprague-Dawley Rat Study2
An Evaluation of Zebrafish, an Emerging Model Analyzing the Effects of Toxicants on Cognitive and Neuromuscular Function2
Biotin2
An Industry Perspective on the Use of Novel Excipients in Lipid Nanoparticles—Nonclinical Considerations2
Hexamidine and Hexamidine Diisethionate2
A Review of the Main Considerations for Formulation Development in Preclinical Toxicology Studies2
Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics2
Safety Evaluation of KP-10 (Metastin 45–54) Following once Daily Intravenous Administration for 14 Days in Dog2
Recent Advances in Drug Discovery Toxicology2
Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid™2
Isobutane, Isopentane, Butane, and Propane2
Evaluation of the Expression Profile of Antibiotic-Induced Thrombocytopenia Using the Japanese Adverse Drug Event Report Database2
Protein Expression in the Gastrocnemius Muscle of a Rodent Shrapnel-Injury Model2
Harihara M. Mehendale: A Life Dedicated to Mentoring and Research2
Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study,2
Editor’s note2
Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics2
The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients—The Putative Mechanism Behind ILD2
Safety Assessment of Palm-Derived Ingredients as Used in Cosmetics2
Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate2
Identifying and Understanding Seizure Liability in Drug Development2
Safety Evaluation of a Prototypical Diazirine-Based Covalent Crosslinker and Molecular Adhesive2
Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent2
Editor’s note2
A Retrospective Comparison of Electrocardiographic Parameters in Ketamine and Tiletamine-Zolazepam Anesthetized Indian Rhesus Monkeys (Macaca mulatta)2
In Vitro Evaluation of Vancomycin-Induced Toxicity in Human Primary Knee Chondrocytes2
Sodium Lauryl Sulfoacetate1
BHT – Butylated Hydroxytoluene1
Thank you to our ad hoc reviewers!1
Corrigendum to “Eleventh Triennial Toxicology Salary Survey”1
Putting a Face on Research1
Glyoxal1
Amended Safety Assessment of Triglycerides as Used in Cosmetics1
Safety Assessment of Cocos nucifera (Coconut)-Derived Ingredients as Used in Cosmetics1
Triacetin1
Amended Safety Assessment of Mentha piperita (Peppermint)–Derived Ingredients as Used in Cosmetics1
Safety Assessment of Alkane Diols as Used in Cosmetics1
Assessing the Safety of MA-[D-Leu-4]-OB3, a Synthetic Peptide Leptin Mimetic: Two Pre-Clinical Toxicity Studies in Male and Female C57BL/6 Mice1
Dioscorea Villosa (Wild Yam) Root Extract1
Mutagenicity Assessment of Homologous Series of Methyl Ester Sulphonates (MES) Using the Bacterial Reverse Mutation (Ames) Test1
Safety Assessment of Inorganic Hydroxides as Used in Cosmetics1
Safety Assessment of Citrus Plant- and Seed-Derived Ingredients as Used in Cosmetics1
Mutagenesis and Carcinogenesis Risk Evaluation for AAV and Lentiviral Gene Therapies1
Corrigendum to “Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex”1
PPG-11 and PPG-15 Stearyl Ether1
Methacrylate Ester Monomers1
Distortion Product Otoacoustic Emission Test is Not the Test to Use in Nonclinical Safety Assessment1
Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics1
Phytantriol1
Sodium Naphthalenesulfonate and Sodium Polynaphthalenesulfonate1
Sodium Dehydroacetate and Dehydroacetic Acid1
Juvenile Bone Toxicity: Study Considerations, Regulations, and Techniques for Assessment1
Liquiritigenin Blocks Breast Cancer Progression by Inhibiting Connective Tissue Growth Factor Expression via Up-Regulating miR-383-5p1
Safety Assessment of Ginkgo biloba-Derived Ingredients as Used in Cosmetics1
Apoptotic Effects of a Thioether Analog of Vitamin K3 in a Human Leukemia Cell Line1
Evaluation of Pulmonary Effects of 3-D Printer Emissions From Acrylonitrile Butadiene Styrene Using an Air-Liquid Interface Model of Primary Normal Human-Derived Bronchial Epithelial Cells1
Co-Culturing Rat Dorsal Root Ganglion Neurons With Rat Schwann Cells Protects Them Against the Cytotoxic Effects of Silver and Gold Nanoparticles1
Toxicological Implications of Biological Heterogeneity1
Book Review: Drug Safety Evaluation, Fourth Edition1
Book Review: Hayes’ Principles and Methods of Toxicology1
An Overview of Gene Editing Modalities and Related Non-clinical Testing Considerations1
The Effects of Nanoplastics on the Dopamine System of Cerebrocortical Neurons1
The Spontaneous Incidence of Neurological Clinical Signs in Preclinical Species Using Cage-side Observations or High-definition Video Monitoring: A Retrospective Analysis1
A Health Intersection of Toxicology and Clinical Medicine1
Nonclinical Safety Profile of Sotorasib, a KRASG12C-Specific Covalent Inhibitor for the Treatment of KRAS p.G12C-Mutated Cancer1
Four-Week GLP Immunotoxicity Assessment of Lactoferrin Alpha Produced by Komagataella phaffii in Sprague-Dawley Rats1
The Nonclinical Assessment of Trans-1,3,3,3-tetrafluoropropene (HFO-1234ze (E)), a Near Zero Global Warming Potential Propellant for Use in Metered Dose Inhalation Products1
Erythorbic Acid and Sodium Erythorbate1
MicroRNA-9-5p Is Involved in Lipopolysaccharide-Induced Acute Lung Injury Via the Regulation of Macrophage Polarization1
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