International Journal of Toxicology

Papers
(The median citation count of International Journal of Toxicology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Safety Assessment of Adenosine as Used in Cosmetics17
Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics16
Book Title: Neurotoxicity of Solvents, Vol. 14, 1st Edition. In Advances in Neurotoxicology Series AschnerMichaelCostaLucio G. In: ThrielChristoph van Ed. Neurotoxicity of Solvents - Volume 14, 1st Ed14
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats13
I Wish I Had Known That! Impactful Guidance and Perspectives for a Fulfilling Career in Toxicology13
Isopropyl Lanolate13
Effect of Chronic Consumption of Fluoridated Water on Sciatic Nerve Conduction Velocity in Male Wistar Rats13
A Characterization of the Nonclinical Pharmacology and Toxicology of Aficamten, a Reversible Allosteric Inhibitor of Cardiac Myosin13
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics11
Mink Oil11
In Utero Exposure to Di-n-butyl Phthalate Causes Modulation in Neurotransmitter System of Wistar Rats: A Multigenerational Assessment11
Challenges and Opportunities of Cosmeceutical Regulations: A Global Perspective10
Safety Assessment of Polyhydroxystearic Acid, Poly(3-Hydroxyoctanoic Acid), and Polylactic Acid as Used in Cosmetics10
Inhalation of Particulate-free Diesel Engine Exhaust Induces Pulmonary Histopathological Alterations in Rat Models: Role of TRPV1 Receptors and Oxidative Stress During Sub-acute Exposure10
Sodium α-Olefin Sulfonates9
Glycol Stearate and Glycol Stearate SE9
Recent Advances in Analytical Techniques for Antidepressants Determination in Complex Biological Matrices: A Review9
Amended Safety Assessment of Synthetically Manufactured Amorphous Silica and Hydrated Silica as Used in Cosmetics9
Microplastics: A Narrative Review on Modes of Exposure and Impact on Human Health9
Hepatitis A Virus Infection in Cynomolgus Monkeys Confounds the Safety Evaluation of a Drug Candidate8
Pre-clinical Safety Assessment of Quercetagetin: Insights From Repeated-Dose Toxicity and Genotoxicity Studies8
The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development8
Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics8
In Silico Human Cardiomyocyte Action Potential Modeling: Exploring Ion Channel Input Combinations8
A Commentary on Fasting of Nonclinical Research Animals8
Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics8
Acute and Chronic Toxicity Assessment of Diosgenin Polyethylene Glycol Succinate in Wistar Rats: Safety Evaluation of a Novel Universal Solubilizer8
Model Characterization: Total Body Irradiation or Busulfan for Conditioning in Human Cell Therapy Toxicology and Tumorigenicity Studies using NOD/SCID/IL2Rγnull (NSG) Mice7
Novel Finding of Urinary Erythropoietin as an Early Biomarker of Cisplatin-Induced Nephrotoxicity7
Safety Assessment of Glycolactones as Used in Cosmetics7
Safety Assessment of Hydrogen Peroxide as Used in Cosmetics7
In vitro Safety Assessment of Extracts and Compounds From Plants as Sunscreen Ingredients7
Safety Assessment of Apple-Derived Ingredients as Used in Cosmetics7
Dose Range-Finding Toxicity Study in Rats With Recombinant Human Lactoferrin Produced in Komagataella phaffii6
Amyl Acetate and Isoamyl Acetate6
Polyamino Sugar Condensate6
AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration6
Non-Human Primate Husbandry and Impact on Non-Human Primates Health: Outcomes From an IQ DruSafe/3RS Industrial Benchmark Survey6
Lard and Lard-Derived Ingredients6
Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex6
Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity, Drug Abuse Liability, and Pediatric Safety6
Assessment of Global DNA Methylation in SH-SY5Y Cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam6
Toxicology Certification: The Need, the Value, and an Evolving Landscape5
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats5
Thank you to our ad hoc reviewers!5
Subchronic Oral Toxicity and Genotoxicity Assessment of SCFA 455, a Clostridium butyricum S-45-5 Culture Filtrate Powder5
Comparative Analyses of the Influences of Vehicles on Selected Biological Parameters Following Single-Dose Oral Administration in Sprague-Dawley Rats5
Safety Assessment of Methylxanthines as Used in Cosmetics5
Safety Assessment of Fatty Ethers as Used in Cosmetics5
Effects of Solvent Dimethyl Sulfoxide Invites a Rethink of Its Application in Amyloid Beta Cytotoxicity5
Incidence of Neoplasms and Selected Non-Neoplastic Findings in Control and Positive Control Groups in CByB6F1-Tg(HRAS)2Jic Hemizygous (rasH2 TM ) Mou5
A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults5
Re-Review Summary of PEG Stearates as Used in Cosmetics4
Predictive Modeling of Pharmacokinetic Drug–Drug and Herb–Drug Interactions in Oncology: Insights From PBPK Studies4
Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review4
Exploring the Biological Effects of Polystyrene Nanoplastics on Spermatogenesis: Insights From Transcriptomic Analysis in Mouse Spermatocytes4
Non-Clinical Cell Therapy Development Using the NCG Mouse Model as a Test System4
Re-Review Summary of VA/Crotonates Copolymer as Used in Cosmetics4
Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers4
Safety Assessment of Carica papaya (Papaya)—Derived Ingredients as Used in Cosmetics4
An Industry Perspective on Key Considerations for the ICH S13 Guidance: Nonclinical Safety Evaluations of Oligonucleotide-Based Therapeutics4
The Non-Human Primate in Safety Assessment of a Bifunctional Long-Acting Insulin Analogue3
Safety Assessment of Alkyl Amide MIPA Ingredients as Used in Cosmetics3
Ozone Preexposure Exacerbates Septic Lung Injury Through ADAR1 Modulation and Pyroptosis Activation3
Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics3
Evaluation of the Carcinogenic Potential of Enarodustat (JTZ-951), a Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor, in 26-Week Tg.rasH2 Mouse Study and 2-Year Sprague-Dawley Rat Study3
The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients—The Putative Mechanism Behind ILD3
Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics3
Recent Advances in Drug Discovery Toxicology3
Quaternium-18 and Quaternium-18 Bentonite3
Recovery Animals in Toxicology Studies: An Innovation and Quality Consortium Perspective on Best Practices With Case Study Examples3
Safety Assessment of Radish Root – Derived Ingredients as Used in Cosmetics3
Safety Assessment of Polyquaternium-6 as Used in Cosmetics3
Book Reviews3
Assay-dependent Artifactual Prolongation of Activated Partial Thromboplastin Time (aPTT) in Cynomolgus Monkeys: Potential Role of POEGMA3
Safety Assessment of Levulinic Acid and Sodium Levulinate as Used in Cosmetics3
Mitochondria: Key Mediator for Environmental Toxicant–Induced Neurodegeneration3
NRX-101, a Rapid-Acting Anti-Depressant, Does Not Cause Neurotoxicity Following Ketamine Administration in Preclinical Models3
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics3
Safety Assessment of Basic Yellow 57 as Used in Cosmetics3
Safety Assessment of Barley-Derived Ingredients as Used in Cosmetics3
Safety Assessment of Centella asiatica -Derived Ingredients as Used in Cosmetics3
Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics3
Eleventh Triennial Toxicology Salary Survey2
An Evaluation of Zebrafish, an Emerging Model Analyzing the Effects of Toxicants on Cognitive and Neuromuscular Function2
Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study,2
Identifying and Understanding Seizure Liability in Drug Development2
Safety Assessment of Melaleuca alternifolia (Tea Tree)-Derived Ingredients as Used in Cosmetics2
BHT – Butylated Hydroxytoluene2
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics2
Editor’s note2
Safety Assessment of Dodecanedioic Acid (Dodecanedioic Acid Disodium Salt) Using Genotoxicity and Repeated 28-day Oral Toxicological Evaluation2
Pathology as a Core Discipline in the Biological Evaluation of Medical Devices2
Hexamidine and Hexamidine Diisethionate2
Editor’s note2
Mutagenesis and Carcinogenesis Risk Evaluation for AAV and Lentiviral Gene Therapies2
Safety Evaluation of a Prototypical Diazirine-Based Covalent Crosslinker and Molecular Adhesive2
Biotin2
Safety Assessment of Palm-Derived Ingredients as Used in Cosmetics2
In Vitro Evaluation of Vancomycin-Induced Toxicity in Human Primary Knee Chondrocytes2
Safety Assessment of Salvia officinalis (Sage)-Derived Ingredients as Used in Cosmetics2
Translational Challenges From Nonclinical to Clinical Program: Case Study Examples2
A Retrospective Comparison of Electrocardiographic Parameters in Ketamine and Tiletamine-Zolazepam Anesthetized Indian Rhesus Monkeys ( Macaca mulatta )2
Re-Review Summary of Sodium Sesquicarbonate, Sodium Carbonate, and Sodium Bicarbonate as Used in Cosmetics2
Isobutane, Isopentane, Butane, and Propane2
Harihara M. Mehendale: A Life Dedicated to Mentoring and Research2
Methylglyoxal Aggregates α-Synuclein by Inhibiting SIRT1-Hif-1α in Intestinal Enteroendocrine Cells2
An Industry Perspective on the Use of Novel Excipients in Lipid Nanoparticles—Nonclinical Considerations2
Safety Assessment of Scutellaria baicalensis -Derived Ingredients as Used in Cosmetics2
Safety Assessment of Zingiber officinale (Ginger) – Derived Ingredients as Used in Cosmetics2
Thank you to our ad hoc reviewers!2
Safety Assessment of Ginkgo biloba -Derived Ingredients as Used in Cosmetics1
Nonclinical Safety Profiles of mRNA Therapeutics Comprising Unmodified or N1-Methyl-Pseudouridine-Modified Nucleosides Are Similar Following Repeated Administration1
Re-Review Summary of Cholesterol as Used in Cosmetics1
Mutagenicity Assessment of Homologous Series of Methyl Ester Sulphonates (MES) Using the Bacterial Reverse Mutation (Ames) Test1
Sodium Naphthalenesulfonate and Sodium Polynaphthalenesulfonate1
Advanced Glycation End Products Induce Cuproptosis and Then Promote the Activation and Migration of Cardiac Fibroblasts1
Re-Review Summary of Ricinus Communis (Castor) Seed Oil and Ricinoleates as Used in Cosmetics1
Safety Assessment of Cocos nucifera (Coconut)-Derived Ingredients as Used in Cosmetics1
Erythorbic Acid and Sodium Erythorbate1
Corrigendum to “Eleventh Triennial Toxicology Salary Survey”1
Thank you to our ad hoc reviewers!1
Safety Assessment of Basic Yellow 87 as Used in Cosmetics1
Sodium Lauryl Sulfoacetate1
Safety Evaluation of Intranasal Nalmefene in Juvenile Rat Studies in Support of Clinical Trials in Pediatric Patients From Birth to 12 Years of Age1
Sodium Dehydroacetate and Dehydroacetic Acid1
An Overview of Gene Editing Modalities and Related Non-clinical Testing Considerations1
Preclinical Safety Evaluation of BB106, a Novel Ketamine–Sulfobutylether-Beta-Cyclodextrin Salt, Following Subcutaneous Administration in Rats and Göttingen Minipigs1
Amended Safety Assessment of Triglycerides as Used in Cosmetics1
PPG-11 and PPG-15 Stearyl Ether1
Four-Week GLP Immunotoxicity Assessment of Lactoferrin Alpha Produced by Komagataella phaffii in Sprague-Dawley Rats1
Safety Assessment of Alkane Diols as Used in Cosmetics1
Safety Assessment of Vanilla as Used in Cosmetics1
Juvenile Bone Toxicity: Study Considerations, Regulations, and Techniques for Assessment1
Assessing the Safety of MA-[D-Leu-4]-OB3, a Synthetic Peptide Leptin Mimetic: Two Pre-Clinical Toxicity Studies in Male and Female C57BL/6 Mice1
Dioscorea Villosa (Wild Yam) Root Extract1
Safety Assessment of Diacetone Alcohol as Used in Cosmetics1
Phytantriol1
Co-Culturing Rat Dorsal Root Ganglion Neurons With Rat Schwann Cells Protects Them Against the Cytotoxic Effects of Silver and Gold Nanoparticles1
Amended Safety Assessment of Mentha piperita (Peppermint)–Derived Ingredients as Used in Cosmetics1
The Spontaneous Incidence of Neurological Clinical Signs in Preclinical Species Using Cage-side Observations or High-definition Video Monitoring: A Retrospective Analysis1
The Comparative Sensitivity to Ketamine-Induced Neuronal Death in Juvenile and Adult Rats1
Safety and Toxicological Evaluation of Subunit Keyhole Limpet Hemocyanin-Loaded Lipid–PLGA Hybrid Nanoparticles (sKLH-hNPs) as a Nanocarrier for an Opioid Use Disorder Vaccine1
Triacetin1
Integrin αvβ3 Antagonist Ameliorates Atherosclerotic Progression by Reducing Platelet Hyperactivation1
Safety Assessment of Diatomaceous Earth as Used in Cosmetics1
Safety Assessment of Starch Phosphates as Used in Cosmetics1
Titanium Complexes as Used in Cosmetics1
Corrigendum to “Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex”1
The Nonclinical Assessment of Trans-1,3,3,3-tetrafluoropropene (HFO-1234ze (E)), a Near Zero Global Warming Potential Propellant for Use in Metered Dose Inhalation Products1
Assessing the Neurotoxicity of Bisphenol A Using Network Toxicology, Molecular Docking, and Molecular Dynamics Simulation1
MicroRNA-9-5p Is Involved in Lipopolysaccharide-Induced Acute Lung Injury Via the Regulation of Macrophage Polarization1
Investigating the Impact of Bisphenol A on Gastric Cancer Through Network Toxicology and Molecular Docking1
Amended Safety Assessment of Naturally-Sourced Clays as Used in Cosmetics1
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