International Journal of Toxicology

Papers
(The median citation count of International Journal of Toxicology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats20
Safety Assessment of Adenosine as Used in Cosmetics20
Isopropyl Lanolate16
Mink Oil14
Effect of Chronic Consumption of Fluoridated Water on Sciatic Nerve Conduction Velocity in Male Wistar Rats13
In Utero Exposure to Di-n-butyl Phthalate Causes Modulation in Neurotransmitter System of Wistar Rats: A Multigenerational Assessment12
Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro11
Editor’s Response to Jorge A. García-Valenzuela and Martha R. Baez-Gaxiola9
A Characterization of the Nonclinical Pharmacology and Toxicology of Aficamten, a Reversible Allosteric Inhibitor of Cardiac Myosin9
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics9
I Wish I Had Known That! Impactful Guidance and Perspectives for a Fulfilling Career in Toxicology9
Glycol Stearate and Glycol Stearate SE8
Sodium α-Olefin Sulfonates8
Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics8
Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics8
In Silico Human Cardiomyocyte Action Potential Modeling: Exploring Ion Channel Input Combinations8
Recent Advances in Analytical Techniques for Antidepressants Determination in Complex Biological Matrices: A Review7
In vitro Safety Assessment of Extracts and Compounds From Plants as Sunscreen Ingredients7
Safety Assessment of Apple-Derived Ingredients as Used in Cosmetics7
Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics7
The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development7
Editor’s Note7
Amended Safety Assessment of Acid Violet 43 as Used in Cosmetics7
Hepatitis A Virus Infection in Cynomolgus Monkeys Confounds the Safety Evaluation of a Drug Candidate6
Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics6
Safety Assessment of Hydrogen Peroxide as Used in Cosmetics6
Novel Finding of Urinary Erythropoietin as an Early Biomarker of Cisplatin-Induced Nephrotoxicity6
Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species6
Model Characterization: Total Body Irradiation or Busulfan for Conditioning in Human Cell Therapy Toxicology and Tumorigenicity Studies using NOD/SCID/IL2Rγnull (NSG) Mice6
A Commentary on Fasting of Nonclinical Research Animals6
Polyamino Sugar Condensate5
Dose Range-Finding Toxicity Study in Rats With Recombinant Human Lactoferrin Produced in Komagataella phaffii5
Assessment of Global DNA Methylation in SH-SY5Y Cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam5
Amyl Acetate and Isoamyl Acetate5
Lard and Lard-Derived Ingredients5
Toxicology Certification: The Need, the Value, and an Evolving Landscape5
Safety Assessment of Methylxanthines as Used in Cosmetics5
Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review4
A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults4
Book Review: Reproductive and Developmental Toxicology Third Edition4
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats4
Effects of Solvent Dimethyl Sulfoxide Invites a Rethink of Its Application in Amyloid Beta Cytotoxicity4
Thank you to our ad hoc reviewers!4
Book Review: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals4
Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity, Drug Abuse Liability, and Pediatric Safety4
Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex4
Predictive Modeling of Pharmacokinetic Drug–Drug and Herb–Drug Interactions in Oncology: Insights From PBPK Studies4
Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines4
Comparative Analyses of the Influences of Vehicles on Selected Biological Parameters Following Single-Dose Oral Administration in Sprague-Dawley Rats4
AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration4
Non-Human Primate Husbandry and Impact on Non-Human Primates Health: Outcomes From an IQ DruSafe/3RS Industrial Benchmark Survey4
Safety Assessment of Keratin and Keratin-Derived Ingredients as Used in Cosmetics4
Quaternium-18 and Quaternium-18 Bentonite3
Exploring the Biological Effects of Polystyrene Nanoplastics on Spermatogenesis: Insights From Transcriptomic Analysis in Mouse Spermatocytes3
Book Review: Haschek and Rousseaux’s Handbook of Toxicologic Pathology3
Chromium [Cr(VI)] Exposure Causes Cytotoxicity of Human Bronchial Epithelial Cells (16-HBE) and Proteomic Alterations3
Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics3
Shp2 in Alveolar Macrophages Regulates Macrophage I Phenotype in Acute Lung Injury3
Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers3
Non-Clinical Cell Therapy Development Using the NCG Mouse Model as a Test System3
Recovery Animals in Toxicology Studies: An Innovation and Quality Consortium Perspective on Best Practices With Case Study Examples3
Book Reviews3
Evaluation of the Carcinogenic Potential of Enarodustat (JTZ-951), a Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor, in 26-Week Tg.rasH2 Mouse Study and 2-Year Sprague-Dawley Rat Study3
Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics3
NRX-101, a Rapid-Acting Anti-Depressant, Does Not Cause Neurotoxicity Following Ketamine Administration in Preclinical Models3
Safety Assessment of Alkyl Amide MIPA Ingredients as Used in Cosmetics3
The Non-Human Primate in Safety Assessment of a Bifunctional Long-Acting Insulin Analogue3
Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics3
Safety Assessment of Citrus Fruit-Derived Ingredients as Used in Cosmetics3
Mutagenesis and Carcinogenesis Risk Evaluation for AAV and Lentiviral Gene Therapies2
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics2
Eleventh Triennial Toxicology Salary Survey2
In Vitro Evaluation of Vancomycin-Induced Toxicity in Human Primary Knee Chondrocytes2
Recent Advances in Drug Discovery Toxicology2
Isobutane, Isopentane, Butane, and Propane2
Safety Evaluation of a Prototypical Diazirine-Based Covalent Crosslinker and Molecular Adhesive2
An Evaluation of Zebrafish, an Emerging Model Analyzing the Effects of Toxicants on Cognitive and Neuromuscular Function2
Biotin2
BHT – Butylated Hydroxytoluene2
Harihara M. Mehendale: A Life Dedicated to Mentoring and Research2
A Review of the Main Considerations for Formulation Development in Preclinical Toxicology Studies2
Editor’s note2
Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid™2
Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate2
Comments on the Risks From Exposure to Denatonium Benzoate (Bitrex®): Denatured Alcohol Disinfection and Pandemic Times2
Editor’s note2
Hexamidine and Hexamidine Diisethionate2
Protein Expression in the Gastrocnemius Muscle of a Rodent Shrapnel-Injury Model2
An Industry Perspective on the Use of Novel Excipients in Lipid Nanoparticles—Nonclinical Considerations2
Evaluation of the Expression Profile of Antibiotic-Induced Thrombocytopenia Using the Japanese Adverse Drug Event Report Database2
A Retrospective Comparison of Electrocardiographic Parameters in Ketamine and Tiletamine-Zolazepam Anesthetized Indian Rhesus Monkeys (Macaca mulatta)2
Safety Assessment of Palm-Derived Ingredients as Used in Cosmetics2
The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients—The Putative Mechanism Behind ILD2
Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics2
Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study,2
Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent2
Identifying and Understanding Seizure Liability in Drug Development2
Four-Week GLP Immunotoxicity Assessment of Lactoferrin Alpha Produced by Komagataella phaffii in Sprague-Dawley Rats1
Juvenile Bone Toxicity: Study Considerations, Regulations, and Techniques for Assessment1
Sodium Lauryl Sulfoacetate1
Safety Assessment of Citrus Plant- and Seed-Derived Ingredients as Used in Cosmetics1
Apoptotic Effects of a Thioether Analog of Vitamin K3 in a Human Leukemia Cell Line1
Phytantriol1
Safety Assessment of Ginkgo biloba-Derived Ingredients as Used in Cosmetics1
Methacrylate Ester Monomers1
Distortion Product Otoacoustic Emission Test is Not the Test to Use in Nonclinical Safety Assessment1
Dioscorea Villosa (Wild Yam) Root Extract1
Safety Assessment of Cocos nucifera (Coconut)-Derived Ingredients as Used in Cosmetics1
Triacetin1
Liquiritigenin Blocks Breast Cancer Progression by Inhibiting Connective Tissue Growth Factor Expression via Up-Regulating miR-383-5p1
Amended Safety Assessment of Mentha piperita (Peppermint)–Derived Ingredients as Used in Cosmetics1
Toxicological Implications of Biological Heterogeneity1
Safety and Toxicological Evaluation of Subunit Keyhole Limpet Hemocyanin-Loaded Lipid–PLGA Hybrid Nanoparticles (sKLH-hNPs) as a Nanocarrier for an Opioid Use Disorder Vaccine1
Thank you to our ad hoc reviewers!1
Evaluation of Pulmonary Effects of 3-D Printer Emissions From Acrylonitrile Butadiene Styrene Using an Air-Liquid Interface Model of Primary Normal Human-Derived Bronchial Epithelial Cells1
Co-Culturing Rat Dorsal Root Ganglion Neurons With Rat Schwann Cells Protects Them Against the Cytotoxic Effects of Silver and Gold Nanoparticles1
PPG-11 and PPG-15 Stearyl Ether1
Book Review: Drug Safety Evaluation, Fourth Edition1
An Overview of Gene Editing Modalities and Related Non-clinical Testing Considerations1
The Effects of Nanoplastics on the Dopamine System of Cerebrocortical Neurons1
Putting a Face on Research1
A Health Intersection of Toxicology and Clinical Medicine1
Sodium Naphthalenesulfonate and Sodium Polynaphthalenesulfonate1
Mutagenicity Assessment of Homologous Series of Methyl Ester Sulphonates (MES) Using the Bacterial Reverse Mutation (Ames) Test1
Safety Assessment of Alkane Diols as Used in Cosmetics1
Erythorbic Acid and Sodium Erythorbate1
MicroRNA-9-5p Is Involved in Lipopolysaccharide-Induced Acute Lung Injury Via the Regulation of Macrophage Polarization1
Safety Assessment of Inorganic Hydroxides as Used in Cosmetics1
Corrigendum to “Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex”1
Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics1
Corrigendum to “Eleventh Triennial Toxicology Salary Survey”1
Glyoxal1
The Spontaneous Incidence of Neurological Clinical Signs in Preclinical Species Using Cage-side Observations or High-definition Video Monitoring: A Retrospective Analysis1
Assessing the Safety of MA-[D-Leu-4]-OB3, a Synthetic Peptide Leptin Mimetic: Two Pre-Clinical Toxicity Studies in Male and Female C57BL/6 Mice1
Amended Safety Assessment of Triglycerides as Used in Cosmetics1
Sodium Dehydroacetate and Dehydroacetic Acid1
The Nonclinical Assessment of Trans-1,3,3,3-tetrafluoropropene (HFO-1234ze (E)), a Near Zero Global Warming Potential Propellant for Use in Metered Dose Inhalation Products1
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