International Journal of Toxicology

Papers
(The median citation count of International Journal of Toxicology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro21
Mink Oil17
Effect of Chronic Consumption of Fluoridated Water on Sciatic Nerve Conduction Velocity in Male Wistar Rats15
Safety Assessment of Adenosine as Used in Cosmetics14
In Utero Exposure to Di-n-butyl Phthalate Causes Modulation in Neurotransmitter System of Wistar Rats: A Multigenerational Assessment14
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats12
A Characterization of the Nonclinical Pharmacology and Toxicology of Aficamten, a Reversible Allosteric Inhibitor of Cardiac Myosin11
I Wish I Had Known That! Impactful Guidance and Perspectives for a Fulfilling Career in Toxicology11
Isopropyl Lanolate11
Book Title: Neurotoxicity of Solvents, Vol. 14, 1st Edition. In Advances in Neurotoxicology Series AschnerMichaelCostaLucio G. In: ThrielChristoph van Ed. Neurotoxicity of Solvents - Volume 14, 1st Ed11
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics10
Inhalation of Particulate-free Diesel Engine Exhaust Induces Pulmonary Histopathological Alterations in Rat Models: Role of TRPV1 Receptors and Oxidative Stress During Sub-acute Exposure10
Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics10
Sodium α-Olefin Sulfonates10
Challenges and Opportunities of Cosmeceutical Regulations: A Global Perspective10
Amended Safety Assessment of Synthetically Manufactured Amorphous Silica and Hydrated Silica as Used in Cosmetics9
Recent Advances in Analytical Techniques for Antidepressants Determination in Complex Biological Matrices: A Review9
In Silico Human Cardiomyocyte Action Potential Modeling: Exploring Ion Channel Input Combinations9
Microplastics: A Narrative Review on Modes of Exposure and Impact on Human Health9
Glycol Stearate and Glycol Stearate SE9
Editor’s Note9
The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development8
Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics8
Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics8
Hepatitis A Virus Infection in Cynomolgus Monkeys Confounds the Safety Evaluation of a Drug Candidate7
Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species7
Novel Finding of Urinary Erythropoietin as an Early Biomarker of Cisplatin-Induced Nephrotoxicity7
Model Characterization: Total Body Irradiation or Busulfan for Conditioning in Human Cell Therapy Toxicology and Tumorigenicity Studies using NOD/SCID/IL2Rγnull (NSG) Mice7
Dose Range-Finding Toxicity Study in Rats With Recombinant Human Lactoferrin Produced in Komagataella phaffii6
Safety Assessment of Apple-Derived Ingredients as Used in Cosmetics6
In vitro Safety Assessment of Extracts and Compounds From Plants as Sunscreen Ingredients6
Safety Assessment of Hydrogen Peroxide as Used in Cosmetics6
A Commentary on Fasting of Nonclinical Research Animals6
Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics6
Lard and Lard-Derived Ingredients5
Comparative Analyses of the Influences of Vehicles on Selected Biological Parameters Following Single-Dose Oral Administration in Sprague-Dawley Rats5
Non-Human Primate Husbandry and Impact on Non-Human Primates Health: Outcomes From an IQ DruSafe/3RS Industrial Benchmark Survey5
Toxicology Certification: The Need, the Value, and an Evolving Landscape5
Polyamino Sugar Condensate5
Effects of Solvent Dimethyl Sulfoxide Invites a Rethink of Its Application in Amyloid Beta Cytotoxicity5
Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity, Drug Abuse Liability, and Pediatric Safety5
Book Review: Reproductive and Developmental Toxicology Third Edition5
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats5
Incidence of Neoplasms and Selected Non-Neoplastic Findings in Control and Positive Control Groups in CByB6F1-Tg(HRAS)2Jic Hemizygous (rasH2 TM ) Mouse Carcinogenici5
Amyl Acetate and Isoamyl Acetate5
Safety Assessment of Methylxanthines as Used in Cosmetics4
Thank you to our ad hoc reviewers!4
A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults4
Book Review: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals4
Predictive Modeling of Pharmacokinetic Drug–Drug and Herb–Drug Interactions in Oncology: Insights From PBPK Studies4
Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines4
AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration4
Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review4
Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers4
Exploring the Biological Effects of Polystyrene Nanoplastics on Spermatogenesis: Insights From Transcriptomic Analysis in Mouse Spermatocytes4
Assessment of Global DNA Methylation in SH-SY5Y Cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam4
Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex4
Safety Assessment of Carica papaya (Papaya)—Derived Ingredients as Used in Cosmetics4
Book Review: Haschek and Rousseaux’s Handbook of Toxicologic Pathology4
Re-Review Summary of VA/Crotonates Copolymer as Used in Cosmetics4
Quaternium-18 and Quaternium-18 Bentonite3
The Non-Human Primate in Safety Assessment of a Bifunctional Long-Acting Insulin Analogue3
Safety Assessment of Levulinic Acid and Sodium Levulinate as Used in Cosmetics3
Ozone Preexposure Exacerbates Septic Lung Injury Through ADAR1 Modulation and Pyroptosis Activation3
Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics3
Non-Clinical Cell Therapy Development Using the NCG Mouse Model as a Test System3
Safety Assessment of Alkyl Amide MIPA Ingredients as Used in Cosmetics3
Recovery Animals in Toxicology Studies: An Innovation and Quality Consortium Perspective on Best Practices With Case Study Examples3
Book Reviews3
Safety Assessment of Basic Yellow 57 as Used in Cosmetics3
Shp2 in Alveolar Macrophages Regulates Macrophage I Phenotype in Acute Lung Injury3
Mitochondria: Key Mediator for Environmental Toxicant–Induced Neurodegeneration3
Re-Review Summary of PEG Stearates as Used in Cosmetics3
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics3
Safety Assessment of Polyquaternium-6 as Used in Cosmetics3
Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate3
Evaluation of the Carcinogenic Potential of Enarodustat (JTZ-951), a Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor, in 26-Week Tg.rasH2 Mouse Study and 2-Year Sprague-Dawley Rat Study3
Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics3
NRX-101, a Rapid-Acting Anti-Depressant, Does Not Cause Neurotoxicity Following Ketamine Administration in Preclinical Models3
Eleventh Triennial Toxicology Salary Survey2
Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics2
Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics2
Editor’s note2
Translational Challenges From Nonclinical to Clinical Program: Case Study Examples2
Safety Evaluation of a Prototypical Diazirine-Based Covalent Crosslinker and Molecular Adhesive2
Mutagenesis and Carcinogenesis Risk Evaluation for AAV and Lentiviral Gene Therapies2
Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent2
Biotin2
Re-Review Summary of Sodium Sesquicarbonate, Sodium Carbonate, and Sodium Bicarbonate as Used in Cosmetics2
In Vitro Evaluation of Vancomycin-Induced Toxicity in Human Primary Knee Chondrocytes2
Safety Assessment of Scutellaria baicalensis -Derived Ingredients as Used in Cosmetics2
Chromium [Cr(VI)] Exposure Causes Cytotoxicity of Human Bronchial Epithelial Cells (16-HBE) and Proteomic Alterations2
Recent Advances in Drug Discovery Toxicology2
Editor’s note2
Harihara M. Mehendale: A Life Dedicated to Mentoring and Research2
An Evaluation of Zebrafish, an Emerging Model Analyzing the Effects of Toxicants on Cognitive and Neuromuscular Function2
BHT – Butylated Hydroxytoluene2
An Industry Perspective on the Use of Novel Excipients in Lipid Nanoparticles—Nonclinical Considerations2
Methylglyoxal Aggregates α-Synuclein by Inhibiting SIRT1-Hif-1α in Intestinal Enteroendocrine Cells2
Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study,2
Pathology as a Core Discipline in the Biological Evaluation of Medical Devices2
Safety Assessment of Palm-Derived Ingredients as Used in Cosmetics2
Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid™2
The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients—The Putative Mechanism Behind ILD2
Hexamidine and Hexamidine Diisethionate2
Sodium Lauryl Sulfoacetate2
Identifying and Understanding Seizure Liability in Drug Development2
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics2
A Retrospective Comparison of Electrocardiographic Parameters in Ketamine and Tiletamine-Zolazepam Anesthetized Indian Rhesus Monkeys (Macaca mulatta)2
Isobutane, Isopentane, Butane, and Propane2
Thank you to our ad hoc reviewers!2
Phytantriol1
Co-Culturing Rat Dorsal Root Ganglion Neurons With Rat Schwann Cells Protects Them Against the Cytotoxic Effects of Silver and Gold Nanoparticles1
Safety Assessment of Cocos nucifera (Coconut)-Derived Ingredients as Used in Cosmetics1
Putting a Face on Research1
Methacrylate Ester Monomers1
Glyoxal1
Book Review: Drug Safety Evaluation, Fourth Edition1
Corrigendum to “Eleventh Triennial Toxicology Salary Survey”1
Dioscorea Villosa (Wild Yam) Root Extract1
Sodium Dehydroacetate and Dehydroacetic Acid1
Sodium Naphthalenesulfonate and Sodium Polynaphthalenesulfonate1
Liquiritigenin Blocks Breast Cancer Progression by Inhibiting Connective Tissue Growth Factor Expression via Up-Regulating miR-383-5p1
Amended Safety Assessment of Triglycerides as Used in Cosmetics1
MicroRNA-9-5p Is Involved in Lipopolysaccharide-Induced Acute Lung Injury Via the Regulation of Macrophage Polarization1
Thank you to our ad hoc reviewers!1
Evaluation of Pulmonary Effects of 3-D Printer Emissions From Acrylonitrile Butadiene Styrene Using an Air-Liquid Interface Model of Primary Normal Human-Derived Bronchial Epithelial Cells1
Juvenile Bone Toxicity: Study Considerations, Regulations, and Techniques for Assessment1
Book Review: Hayes’ Principles and Methods of Toxicology1
Safety Assessment of Alkanoyl Lactyl Lactate Salts as Used in Cosmetics1
The Effects of Nanoplastics on the Dopamine System of Cerebrocortical Neurons1
Distortion Product Otoacoustic Emission Test is Not the Test to Use in Nonclinical Safety Assessment1
Safety and Toxicological Evaluation of Subunit Keyhole Limpet Hemocyanin-Loaded Lipid–PLGA Hybrid Nanoparticles (sKLH-hNPs) as a Nanocarrier for an Opioid Use Disorder Vaccine1
PPG-11 and PPG-15 Stearyl Ether1
Re-Review Summary of Cholesterol as Used in Cosmetics1
Mutagenicity Assessment of Homologous Series of Methyl Ester Sulphonates (MES) Using the Bacterial Reverse Mutation (Ames) Test1
Safety Assessment of Alkane Diols as Used in Cosmetics1
Toxicological Implications of Biological Heterogeneity1
Safety Assessment of Vanilla as Used in Cosmetics1
Erythorbic Acid and Sodium Erythorbate1
Safety Assessment of Diacetone Alcohol as Used in Cosmetics1
Titanium Complexes as Used in Cosmetics1
The Nonclinical Assessment of Trans-1,3,3,3-tetrafluoropropene (HFO-1234ze (E)), a Near Zero Global Warming Potential Propellant for Use in Metered Dose Inhalation Products1
Amended Safety Assessment of Mentha piperita (Peppermint)–Derived Ingredients as Used in Cosmetics1
An Overview of Gene Editing Modalities and Related Non-clinical Testing Considerations1
Assessing the Safety of MA-[D-Leu-4]-OB3, a Synthetic Peptide Leptin Mimetic: Two Pre-Clinical Toxicity Studies in Male and Female C57BL/6 Mice1
Triacetin1
Integrin αvβ3 Antagonist Ameliorates Atherosclerotic Progression by Reducing Platelet Hyperactivation1
Corrigendum to “Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex”1
The Spontaneous Incidence of Neurological Clinical Signs in Preclinical Species Using Cage-side Observations or High-definition Video Monitoring: A Retrospective Analysis1
Assessing the Neurotoxicity of Bisphenol A Using Network Toxicology, Molecular Docking, and Molecular Dynamics Simulation1
Safety Assessment of Ginkgo biloba-Derived Ingredients as Used in Cosmetics1
Re-Review Summary of Ricinus Communis (Castor) Seed Oil and Ricinoleates as Used in Cosmetics1
Four-Week GLP Immunotoxicity Assessment of Lactoferrin Alpha Produced by Komagataella phaffii in Sprague-Dawley Rats1
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