OOIR: Observatory of International Research

Papers

(The median citation count of Physiological Genomics is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Fluxomics combined with shotgun proteomics reveals a differential response of bovine kidney cells to extracellular palmitic and α-linolenic acid	25
Now and then in eukaryotic DNA methylation	24
Identification of shared and disease-specific intratumoral microbiome-host gene associations in gastrointestinal tumors	20
Extracellular vesicle-mediated transfer of lncRNA CLDN10-AS1 aggravates low-density lipoprotein-induced vascular endothelial injury	19
The methylome of buccal epithelial cells is influenced by age, sex, and physiological properties	18
Exploring myometrial microenvironment changes at the single-cell level from nonpregnant to term pregnant states	17
Limited WKY chromosomal regions confer increases in anxiety and fear memory in a F344 congenic rat strain	16
Collagen induction of immune cells in the mammary glands during pregnancy	16
Blood pressure and the kidney cortex transcriptome response to high-sodium diet challenge in female nonhuman primates	15
Lysine demethylase KDM6B regulates HIF-1α-mediated systemic and cellular responses to intermittent hypoxia	15
The role of resistance to inhibitors of cholinesterase 8b in the control of heart rate	15
Impact of exercise on brain-bone marrow interactions in chronic stress: potential mechanisms preventing stress-induced hypertension	14
KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model	14
Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown	14
Neuroendocrine, inflammatory, and extracellular vesicle responses during the Navy Special Warfare Screener Selection Course	12
Distribution of cardiomyocyte-selective adeno-associated virus serotype 9 vectors in swine following intracoronary and intravenous infusion	12
Assessing the impact of boldine on the gastrocnemius using multiomics profiling at 7 and 28 days post-complete spinal cord injury in young male mice	12
Molecular signatures of longissimus dorsi differ between dairy cattle based on prepartum muscle reserves and branched-chain volatile fatty acid supplementation	11
Investigative power of genomic informational field theory relative to genome-wide association studies for genotype-phenotype mapping	11
Estradiol-dependent gene expression profile in the amygdala of young ovariectomized spontaneously hypertensive rats	11
Association of SNP-SNP interactions of surfactant protein genes with severity of respiratory syncytial virus infection in children	11
Podocyte cell-specific Npr1 is required for blood pressure and renal homeostasis in male and female mice: role of sex-specific differences	11
Gill ionocyte remodeling mediates blood pH regulation in rockfish (Sebastes diploproa) exposed to environmentally relevant hypercapnia	10
Prolonged obesity alters males’ adipose profile: implications for disease?	9
Single-cell RNA sequencing of mouse left ventricle reveals cellular diversity and intercommunication	9

SARS-CoV-2 transgressing LncRNAs uncovers the known unknowns	9
Single-cell reconstruction and mutation enrichment analysis identifies dysregulated cardiomyocyte and endothelial cells in congenital heart disease	8
MYL9 binding with MYO19 suppresses epithelial-mesenchymal transition in non-small-cell lung cancer	8
Impact of stress phenotype, elevated temperature, and bacterin exposure on male Atlantic salmon (Salmo salar) growth, stress, and immune biomarker gene expression	8
Age-related differences in gene expression and pathway activation following heatstroke	8
Analysis of a genetic region affecting mouse body weight	8
Ameliorating immune-dependent inflammation and apoptosis by targeting TLR4/MYD88/NF-κB pathway by celastrol mitigates the diabetic reproductive dysfunction	7
DNA methylation dynamics in the small intestine of egg-selected laying hens along egg production stages	7
Maternal and fetal mitochondrial gene dysregulation in hypertensive disorders of pregnancy	7
Deciphering taxonomic and functional patterns of microbial communities associated with the tiger tail seahorse (Hippocampus comes)	7
Genetic background determines renal response to chronic lithium treatment in female mice	7
Pregnancy-specific shifts in the maternal microbiome and metabolome in the BPH/5 mouse model of superimposed preeclampsia	7
Exercise to combat cancer: focusing on the ends	7
Transcriptomic changes in glomeruli in response to a high salt challenge in the Dahl SS rat	6
Dysregulation of miR-21-associated miRNA regulatory networks by chronic ethanol consumption impairs liver regeneration	6
Gene coexpression network analysis reveals perirenal adipose tissue as an important target of prenatal malnutrition in sheep	6
miR155 deficiency reduces breast tumor burden in the MMTV-PyMT mouse model	6
Krüppel-like factor 4 in transcriptional control of the three unique isoforms of Agouti-related peptide in mice	6
Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice	6
Transcriptome analysis reveals disruption of circadian rhythms in late gestation dairy cows may increase risk for fatty liver and reduced mammary remodeling	6
Computational modeling of the synergistic role of GCN2 and the HPA axis in regulating the integrated stress response in the central circadian timing system	5
Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat	5
Transcriptomic profiling of the bovine endosalpinx and endometrium to identify putative embryokines	5
The expression profile of 79 genes from 107 viruses revealed new insights into disease susceptibility in rats, mice, and muskrats	5
Echocardiography phenotyping in murine genetic reference population of BXD strains reveals significant QTLs associated with cardiac function and morphology	5
Adrenal gene expression dynamics support hibernation in 13-lined ground squirrels	5
Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study	5
A long-term high-fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice	5
Drivers of transcriptional variance in human intestinal epithelial organoids	5
BRCA1-specific machine learning model predicts variant pathogenicity with high accuracy	5
Genetic drivers of age-related changes in urinary magnesium excretion	5
Epigenetic fluctuations underlie gene expression timescales and variability	5
Circulating extracellular DNA is in association with continuous metabolic syndrome score in healthy adolescents	5
Nutrient composition influences the gut microbiota in chronic thoracic spinal cord-injured rats	5
Immune and metabolic challenges induce changes in pain sensation and related pathways in the hypothalamus	4
Human endogenous retroviruses: our genomic fossils and companions	4
Cardiac biomarker responses following high-intensity interval and continuous exercise: the influence of ACE-I/D gene polymorphism and training status in men	4
Changes in environmental stress over COVID-19 pandemic likely contributed to failure to replicate adiposity phenotype associated with Krtcap3	4
Preexisting hypertension and pregnancy-induced hypertension reveal molecular differences in placental proteome in rodents	4
Shared aspects of mRNA expression associated with oocyte maturation failure in humans and rhesus monkeys indicating compromised oocyte quality	4
Dose-dependent progression of multiple low-dose streptozotocin-induced diabetes in mice	4
Melanocortin MC₄R receptor is required for energy expenditure but not blood pressure effects of angiotensin II within the mouse brain	4
Tumor MK2 transcript levels are associated with improved response to chemotherapy and patient survival in non-small cell lung cancer	4
Hepatic transcriptional profile reveals the role of diet and genetic backgrounds on metabolic traits in female progenitor strains of the Collaborative Cross	4
Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity	4
Redistribution of SOD3 expression due to R213G polymorphism affects pulmonary interstitial macrophage reprogramming in response to hypoxia	4
Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats	4
Unveiling the connection between gut microbiome and metabolic health in individuals with chronic spinal cord injury	4
Chronic binge alcohol and ovariectomy dysregulate omental adipose tissue metaboproteome in simian immunodeficiency virus-infected female macaques	3
Linking inflammatory adipose tissue to placental abnormalities in obese preeclamptic pregnancies	3

Local and systemic transcriptomic responses from acute exercise induced muscle damage of the human knee extensors	3
Knockdown of deoxythymidylate kinase suppresses progression and epithelial-mesenchymal-transition of lung adenocarcinoma via STAT3 signaling	3
Genetically determined exercise capacity affects systemic glucose response to insulin in rats	3
The Atg16l1 gene: characterization of wild type, knock-in, and knock-out phenotypes in rats	3
Chronic jetlag-induced alterations in pancreatic diurnal gene expression	3
Strain-dependent lung transcriptomic differences in cigarette smoke and LPS models of lung injury in mice	3
Dynamic dysregulation of transcriptomic networks in brainstem autonomic nuclei during hypertension development in the female spontaneously hypertensive rat	3
Single-cell transcriptomic heterogeneity between conduit and resistance mesenteric arteries in rats	3
Whole genome transcriptome analysis of the stomach resected in human vertical sleeve gastrectomy: cutting more than calories	3
Unique circulating microRNA associations with dysglycemia in people living with HIV and alcohol use	3
METTL3-mediated m6A modification promotes processing and maturation of pri-miRNA-19a to facilitate nasopharyngeal carcinoma cell proliferation and invasion	3
Dysregulation of early gene response to a mixed meal in skeletal muscle in obesity and type 2 diabetes	3
The influence of nutrients on mechanical overload-induced changes to skeletal muscle mRNA content	3
Reconstitution of the host holobiont in germ-free born male rats acutely increases bone growth and affects marrow cellular content	3
Nrf2 signaling in heart failure: expression of Nrf2, Keap1, antioxidant, and detoxification genes in dilated or ischemic cardiomyopathy	3
Na⁺/Cl⁻ cotransporter 2 is not fish-specific and is widely found in amphibians, non-avian reptiles, and select mammals	2
Divergent selection for feed efficiency in pigs altered the duodenum transcriptomic response to feed intake and its DNA methylation profiles	2
MicroRNA cargo of extracellular vesicles released by skeletal muscle fibro-adipogenic progenitor cells is significantly altered with disuse atrophy and IL-1β deficiency	2
The effect of high-fiber diet based on gut microbiota in patients with chronic heart failure	2
Systems genetics analysis defines importance of TMEM43/LUMA for cardiac- and metabolic-related pathways	2
Can abnormal chromatin folding cause high-penetrance cancer predisposition?	2
Comparison of long- and short-rest periods during high-intensity interval exercise on transcriptomic responses in equine skeletal muscle	2
mRatBN7.2: familiar and unfamiliar features of a new rat genome reference assembly	2
Integrative physiology of lysine metabolites	2
The uterine secretory cycle: recurring physiology of endometrial outputs that setup the uterine luminal microenvironment	2
Temporal shifts to the gut microbiome associated with cognitive dysfunction following high-fat diet consumption in a juvenile model of traumatic brain injury	2
Effects of the anti-inflammatory drug budesonide on the gut microbiota and cytokine production of 13-lined ground squirrels during prehibernation fattening	2
Physiological, biochemical, and genome-wide expression patterns during graded normobaric hypoxia in healthy individuals	2
Bone marrow mesenchymal stem cells repress renal transplant immune rejection by facilitating the APRIL phosphorylation to induce regulation B cell production	2
Transcriptional response of the heart to vagus nerve stimulation	2
Liver transcriptome response to periparturient hormonal and metabolic changes depends on the postpartum occurrence of subacute ruminal acidosis in Holstein cows	2
Integrated analysis of methylome and transcriptome responses to exercise training in children with overweight/obesity	2
Three decades of rat genomics: approaching the finish(ed) line	2
Drinking pattern and sex modulate the impact of ethanol consumption on the mouse gut microbiome	2
Mitochondrial microRNA profiles are altered in thirteen-lined ground squirrels (Ictidomys tridecemlineatus) during hibernation	2
Endothelial to mesenchymal transition in neonatal hyperoxic lung injury: role of sex as a biological variable	2
The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females	2
Integrated analysis of transcriptome profiling of lncRNAs and mRNAs in livers of type 2 diabetes mellitus	2
Interactions between type of culture medium and addition of serum on development and gene expression of bovine blastocysts produced in vitro	2
Genomic and epigenomic active vitamin D responses in human colonic organoids	1
Platelet proteome dynamics in hibernating 13-lined ground squirrels	1
Landscape of the intratumoral microbiota acting on the tumor immune microenvironment in LUAD and LUSC	1
Predictive modeling of oocyte maternal mRNA features for five mammalian species reveals potential shared and species-restricted regulators during maturation	1
Single-cell profiling of the peripheral blood immune landscape during mid- and late-stage pregnancy	1
Hypothalamic transcriptome response to simulated diel earthen pond hypoxia cycles in channel catfish (Ictalurus punctatus)	1
Dysregulation of cholesterol homeostasis is an early signal of β-cell proteotoxicity characteristic of type 2 diabetes	1
Fecal dysbiosis and inflammation in intestinal-specific Cftr knockout mice on regimens preventing intestinal obstruction	1
Novel whole blood transcriptome signatures of changes in maximal aerobic capacity in response to endurance exercise training in healthy women	1
Comparative transcriptome analysis of experimental cryptorchidism: of mice and cynomolgus monkeys	1
Knockout of Hsp70 genes significantly affects locomotion speed and gene expression in leg skeletal muscles of Drosophila melanogaster	1
Subdiaphragmatic vagal nerve stimulation attenuates the development of hypertension and alters nucleus of the solitary tract transcriptional networks in the spontaneously hypertensive rat	1
Gene expression profile and injury sites in mice treated with Shiga toxin 2 and lipopolysaccharide as a Shiga toxin-associated hemolytic uremic syndrome model	1
Specific circulating miRNAs are associated with plasma lipids in a healthy American cohort	1
Microbiota-induced inflammatory responses in bladder tumors promote epithelial-mesenchymal transition and enhanced immune infiltration	1
Dynamic changes in gene expression of growing nonhuman primate antral follicles	1
LncRNA CARMN inhibits cervical cancer cell growth via the miR-92a-3p/BTG2/Wnt/β-catenin axis	1
Analysis of microRNA expression in rat kidneys after VEGF inhibitor treatment under different degrees of hypoxia	1
Potential molecular mechanisms of Jiedu Tongluo Tiaogan Formula in treating hyperthyroidism based on network pharmacology and in vivo experiments in mice	1
Colorectal cancer subtyping and prognostic model construction based on interleukin-related genes	1
MicroRNA-499-5p promotes vascular smooth muscle cell proliferation and migration via inhibiting SOX6	1
Polycystin-2-dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease	1
Integrated microarray for identifying the hub mRNAs and constructed miRNA-mRNA network in coronary in-stent restenosis	1
Highlighting recent impactful publications in Physiological Genomics	1
Characteristics of circular RNAs expression of peripheral blood mononuclear cells in humans with coronary artery disease	1
Optimization of mouse kidney digestion protocols for single-cell applications	1
Colonic responses to aspirin treatment - transcriptome effects by dose, time and ancestry	1
Relationship between Guillain–Barré syndrome and cardiovascular disease: a bidirectional Mendelian randomization study	1
Transcriptomics and proteomics revealed sex differences in human pulmonary microvascular endothelial cells	1
PANoptosis in vascular smooth muscle cells regulated by TNF-α/IL-1β can be a new target for alleviating the progression of abdominal aortic aneurysm	1
Vacuole membrane protein 1 and acute response to renal ischemia and ischemia/reperfusion	1
Parental cardiorespiratory fitness influences early life energetics and metabolic health	1
White-throated sparrow (Zonotrichia albicollis) liver and pectoralis flight muscle transcriptomic changes in preparation for migration	1
Global phosphoproteomic profiling of skeletal muscle in ovarian hormone-deficient mice	1
Long-term epigenetic and metabolomic changes in the mouse ventricular myocardium after exertional heat stroke	1
The adducin saga: pleiotropic genomic targets for precision medicine in human hypertension—vascular, renal, and cognitive diseases	1
Integrated genomics approaches identify transcriptional mediators and epigenetic responses to Afghan desert particulate matter in small airway epithelial cells	1