OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Genomics is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
The COVID-19 pandemic: a global health crisis	270
SARS-CoV-2, ACE2 expression, and systemic organ invasion	101
Harnessing innate immunity to eliminate SARS-CoV-2 and ameliorate COVID-19 disease	75
Sleep fragmentation increases blood pressure and is associated with alterations in the gut microbiome and fecal metabolome in rats	59
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project	55
Silencing of MYH7 ameliorates disease phenotypes in human iPSC-cardiomyocytes	31
Oxytocin’s anti-inflammatory and proimmune functions in COVID-19: a transcriptomic signature-based approach	31
Implementation of convolutional neural network approach for COVID-19 disease detection	30
Cell dormancy plasticity: quiescence deepens into senescence through a dimmer switch	26
Cell-free DNA and RNA—measurement and applications in clinical diagnostics with focus on metabolic disorders	23
Virus-induced genetics revealed by multidimensional precision medicine transcriptional workflow applicable to COVID-19	21
Nrf2 signaling in heart failure: expression of Nrf2, Keap1, antioxidant, and detoxification genes in dilated or ischemic cardiomyopathy	18
Drivers of transcriptional variance in human intestinal epithelial organoids	18
Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLD	17
Functional genomics analysis of human colon organoids identifies key transcription factors	16
Characterization of the endometrial transcriptome in early diestrus influencing pregnancy status in dairy cattle after transfer of in vitro-produced embryos	16
Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia	16
Methylation of histone 4’s lysine 20: a critical analysis of the state of the field	15
Transcriptomic signature of fasting in human adipose tissue	14
Machine learning-based classification and diagnosis of clinical cardiomyopathies	14
Can cilia provide an entry gateway for SARS-CoV-2 to human ciliated cells?	13
Genomic and epigenomic active vitamin D responses in human colonic organoids	12
Frequency and management of medically actionable incidental findings from genome and exome sequencing data: a systematic review	12
Lysine demethylase KDM6B regulates HIF-1α-mediated systemic and cellular responses to intermittent hypoxia	12
Muscle transcriptional networks linked to resistance exercise training hypertrophic response heterogeneity	12

Identification of a peripheral blood gene signature predicting aortic valve calcification	11
High-fat diet negatively impacts both metabolic and behavioral health in outbred heterogeneous stock rats	11
Molecular signatures of muscle growth and composition deciphered by the meta-analysis of age-related public transcriptomics data	11
Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise	10
Systems genetics analysis defines importance of TMEM43/LUMA for cardiac- and metabolic-related pathways	10
eQTL variants in COL22A1 are associated with muscle injury in athletes	10
Integration of metabolomics and transcriptomics reveals convergent pathways driving radiation-induced salivary gland dysfunction	10
Probing metabolic memory in the hepatic response to fasting	10
Global phosphoproteomic profiling of skeletal muscle in ovarian hormone-deficient mice	10
Time-course analysis of the effect of embedded metal on skeletal muscle gene expression	10
Difference in potential DNA methylation impact on gene expression between fast- and slow-type myofibers	9
Gene expression of the IGF hormones and IGF binding proteins across time and tissues in a model reptile	9
Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity	9
Characteristics of circular RNAs expression of peripheral blood mononuclear cells in humans with coronary artery disease	9
Gestational gut microbial remodeling is impaired in a rat model of preeclampsia superimposed on chronic hypertension	8
mRatBN7.2: familiar and unfamiliar features of a new rat genome reference assembly	8
High-resolution analysis of differential gene expression during skeletal muscle atrophy and programmed cell death	8
Progesterone-dependent and progesterone-independent modulation of luminal epithelial transcription to support pregnancy in cattle	8
METTL3-mediated m6A modification promotes processing and maturation of pri-miRNA-19a to facilitate nasopharyngeal carcinoma cell proliferation and invasion	8
Platelet proteome dynamics in hibernating 13-lined ground squirrels	8
Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice	8
Gut microbiota of wild fish as reporters of compromised aquatic environments sleuthed through machine learning	7
Human endogenous retroviruses: our genomic fossils and companions	7
Chronic jetlag-induced alterations in pancreatic diurnal gene expression	7
Transcriptome analysis reveals disruption of circadian rhythms in late gestation dairy cows may increase risk for fatty liver and reduced mammary remodeling	7
Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats	7
Distribution of cardiomyocyte-selective adeno-associated virus serotype 9 vectors in swine following intracoronary and intravenous infusion	7
The Atg16l1 gene: characterization of wild type, knock-in, and knock-out phenotypes in rats	6
Liver transcriptome response to periparturient hormonal and metabolic changes depends on the postpartum occurrence of subacute ruminal acidosis in Holstein cows	6
Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study	6
Integrated analysis of transcriptome profiling of lncRNAs and mRNAs in livers of type 2 diabetes mellitus	6
An integrative proteogenomics approach reveals peptides encoded by annotated lincRNA in the mouse kidney inner medulla	6
The adducin saga: pleiotropic genomic targets for precision medicine in human hypertension—vascular, renal, and cognitive diseases	6