OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Cell is 91. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
SLC4A7 and mTORC1 raise nucleotide synthesis with bicarbonate	772
TADs do not stay in the loop	760
S6K1 Regulates GSK3 under Conditions of mTOR-Dependent Feedback Inhibition of Akt	517
Meet the authors: Meiling Wang, Wenjing Li, and Weixing Zhao	468
Meet the authors: Shouqiao Hou and Daichao Xu	443
You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion	309
BARBEKO’ing in the lab: Versatile CRISPR screens with barcoded base editors	308
A DNA helicase remodeling proteins: How DNA-protein crosslink repair unfolds via FANCJ	303
eIF4G as a switch for heat shock mRNA translation	295
The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs	291
Meet the authors: Mei-Sheng Xiao, Arun Prasath Damodaran, and Thomas Gonatopoulos-Pournatzis	276
Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers	274
Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain	273
The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release	262
CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance	246
The molecular basis of tRNA selectivity by human pseudouridine synthase 3	240
HelR is a helicase-like protein that protects RNA polymerase from rifamycin antibiotics	222
Altered nucleocytoplasmic export of adenosine-rich circRNAs by PABPC1 contributes to neuronal function	218
Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses	215
SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis	213
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition	212
Cryo-EM structure of the periplasmic tunnel of T7 DNA-ejectosome at 2.7 Å resolution	211
POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps	209
TIGR on the loose: A dual-guide RNA system for DNA targeting	201
ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition	193

RNA polymerase and ppGpp deliver a one-two punch to antibiotics	192
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication	186
Mitochondria: A “pacemaker” for species-specific development	184
Sister chromatid cohesion halts DNA loop expansion	177
Gene architecture directs splicing outcome in separate nuclear spatial regions	177
BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation	175
FUBP1 is a general splicing factor facilitating 3′ splice site recognition and splicing of long introns	173
Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID	169
DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production	168
Spatial control of m6A deposition on enhancer and promoter RNAs through co-acetylation of METTL3 and H3K27 on chromatin	166
Now open: Evolving insights to the roles of lysine acetylation in chromatin organization and function	158
INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II	158
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs	155
RNA:DNA hybrids from Okazaki fragments contribute to establish the Ku-mediated barrier to replication-fork degradation	147
Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions	146
STING: Stay near to STIM(1) neuroprotection	145
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha	145
Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes	142
Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease	140
Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses	139
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules	137
Nucleosomes specify co-factor access to p53	137
Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB	135
Hydrogen sulfide: A whiff of trouble for cancer cell survival	135
Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP	135
Mitochondrial protein transport: Versatility of translocases and mechanisms	130
MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape	130
Introducing new group leaders: Wen Zhou	129
Silent silencers: Leave no trace	126
Bacterial ligases reveal fundamental principles of polyubiquitin specificity	123
The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress	122
FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress	121
Mycobacterium abscessus HelR interacts with RNA polymerase to confer intrinsic rifamycin resistance	117
A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization	117
Senescence suppresses the integrated stress response and activates a stress-remodeled secretory phenotype	114
ATR promotes clearance of damaged DNA and damaged cells by rupturing micronuclei	113
Filament formation activates protease and ring nuclease activities of CRISPR Lon-SAVED	112
Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination	111
A new chromatin flavor to cap chromosomes: Where structure, function, and evolution meet	110
A domain of all trades: The enzymatic versatility of the NiRAN domain	109
Are nanopore technologies ready for the proteomic challenge primetime?	109
Meet the authors: Irene Beusch and Hiten Madhani	108
Meet the authors: Emily R. Feierman and Erica Korb	102
Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin	101
Dual allosteric modulation of voltage and calcium sensitivities of the Slo1-LRRC channel complex	101
NLRP12 senses heme and PAMPs to drive necrotic cell death and inflammation	101
A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells	99
Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma	99
BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability	98
The γ-secretase substrate proteome and its role in cell signaling regulation	98

Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag	97
Bacterial Shedu immune nucleases share a common enzymatic core regulated by diverse sensor domains	96
Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2	96
VPS4A is the selective receptor for lipophagy in mice and humans	95
The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism	95
Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity	95
A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis	95
ZC3H14 facilitates backsplicing by binding to exon-intron boundary and 3′ UTR	94
Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest	93
IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance	93
Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome	93
Single-molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes	92
Recent technical advances in the study of nucleic acid modifications	92
Structural snapshots of R-loop formation by a type I-C CRISPR Cascade	91
Heat shock induces premature transcript termination and reconfigures the human transcriptome	91
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate	91