OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Cell is 92. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
SLC4A7 and mTORC1 raise nucleotide synthesis with bicarbonate	816
S6K1 Regulates GSK3 under Conditions of mTOR-Dependent Feedback Inhibition of Akt	810
Meet the authors: Meiling Wang, Wenjing Li, and Weixing Zhao	532
Meet the authors: Shouqiao Hou and Daichao Xu	489
You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion	466
A DNA helicase remodeling proteins: How DNA-protein crosslink repair unfolds via FANCJ	319
eIF4G as a switch for heat shock mRNA translation	318
The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs	316
Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers	311
Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain	301
The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release	288
HelR is a helicase-like protein that protects RNA polymerase from rifamycin antibiotics	285
Altered nucleocytoplasmic export of adenosine-rich circRNAs by PABPC1 contributes to neuronal function	283
TIGR on the loose: A dual-guide RNA system for DNA targeting	270
ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition	263
RNA polymerase and ppGpp deliver a one-two punch to antibiotics	227
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication	225
Mitochondria: A “pacemaker” for species-specific development	216
Sister chromatid cohesion halts DNA loop expansion	215
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha	211
DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production	211
CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance	196
BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation	193
The molecular basis of tRNA selectivity by human pseudouridine synthase 3	191
Structural determinants of DANGEROUS MIX 3, an alpha/beta hydrolase that triggers NLR-mediated genetic incompatibility in plants	184

Meet the authors: Mei-Sheng Xiao, Arun Prasath Damodaran, and Thomas Gonatopoulos-Pournatzis	183
STING: Stay near to STIM(1) neuroprotection	182
MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape	177
Spatial control of m6A deposition on enhancer and promoter RNAs through co-acetylation of METTL3 and H3K27 on chromatin	175
Nucleosomes specify co-factor access to p53	173
Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID	172
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition	164
Gene architecture directs splicing outcome in separate nuclear spatial regions	162
SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis	157
Hydrogen sulfide: A whiff of trouble for cancer cell survival	157
The power of two: Combining imaging and sequencing as readouts for in vivo pooled genetic screens	156
Sticky business: Rationalizing CRBN’s zinc-finger targeting by molecular glues	152
Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses	149
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules	144
INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II	143
Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes	142
Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses	140
Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB	140
Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions	140
FUBP1 is a general splicing factor facilitating 3′ splice site recognition and splicing of long introns	138
RNA:DNA hybrids from Okazaki fragments contribute to establish the Ku-mediated barrier to replication-fork degradation	137
Mitochondrial protein transport: Versatility of translocases and mechanisms	135
Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease	133
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs	131
Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP	126
TADs do not stay in the loop	125
POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps	123
Now open: Evolving insights to the roles of lysine acetylation in chromatin organization and function	122
Introducing new group leaders: Wen Zhou	120
The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress	117
Bacterial ligases reveal fundamental principles of polyubiquitin specificity	117
Mycobacterium abscessus HelR interacts with RNA polymerase to confer intrinsic rifamycin resistance	116
Senescence suppresses the integrated stress response and activates a stress-remodeled secretory phenotype	114
Filament formation activates protease and ring nuclease activities of CRISPR Lon-SAVED	113
Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma	112
The γ-secretase substrate proteome and its role in cell signaling regulation	111
Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest	110
Silent silencers: Leave no trace	108
FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress	105
Are nanopore technologies ready for the proteomic challenge primetime?	105
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate	104
A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis	104
VPS4A is the selective receptor for lipophagy in mice and humans	104
ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency	103
Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin	102
A new chromatin flavor to cap chromosomes: Where structure, function, and evolution meet	101
Universal features of Nsp1-mediated translational shutdown by coronaviruses	101
A domain of all trades: The enzymatic versatility of the NiRAN domain	99
Single-molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes	97
NLRP12 senses heme and PAMPs to drive necrotic cell death and inflammation	97

Heat shock induces premature transcript termination and reconfigures the human transcriptome	97
Meet the authors: Irene Beusch and Hiten Madhani	97
Structural basis for product specificities of MLL family methyltransferases	95
Structural snapshots of R-loop formation by a type I-C CRISPR Cascade	95
A tRF nucleator for Nucleolin in cancer metastasis	94
Putative looping factor ZNF143/ZFP143 is an essential transcriptional regulator with no looping function	94
A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization	94
BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability	93
Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms	93
Bacterial Shedu immune nucleases share a common enzymatic core regulated by diverse sensor domains	93
Meet the authors: Emily R. Feierman and Erica Korb	93
ZC3H14 facilitates backsplicing by binding to exon-intron boundary and 3′ UTR	92
Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling	92
The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism	92
Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2	92
Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination	92
Structural basis for promoter recognition and transcription factor binding and release in human mitochondria	92