OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Cell is 89. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Structural determinants of DANGEROUS MIX 3, an alpha/beta hydrolase that triggers NLR-mediated genetic incompatibility in plants	894
Meet the authors: Mei-Sheng Xiao, Arun Prasath Damodaran, and Thomas Gonatopoulos-Pournatzis	567
STING: Stay near to STIM(1) neuroprotection	537
Meet the authors: Shouqiao Hou and Daichao Xu	503
CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance	340
Nucleosomes specify co-factor access to p53	316
Hydrogen sulfide: A whiff of trouble for cancer cell survival	306
RNA:DNA hybrids from Okazaki fragments contribute to establish the Ku-mediated barrier to replication-fork degradation	305
FUBP1 is a general splicing factor facilitating 3′ splice site recognition and splicing of long introns	286
ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition	283
Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease	244
Spatial control of m6A deposition on enhancer and promoter RNAs through co-acetylation of METTL3 and H3K27 on chromatin	235
Now open: Evolving insights to the roles of lysine acetylation in chromatin organization and function	231
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication	229
Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses	221
Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB	217
Sister chromatid cohesion halts DNA loop expansion	198
Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP	198
MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape	193
Sticky business: Rationalizing CRBN’s zinc-finger targeting by molecular glues	192
The power of two: Combining imaging and sequencing as readouts for in vivo pooled genetic screens	192
eIF4G as a switch for heat shock mRNA translation	190
TIGR on the loose: A dual-guide RNA system for DNA targeting	186
RNA polymerase and ppGpp deliver a one-two punch to antibiotics	185
SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis	183

The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release	174
Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID	172
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha	169
Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers	165
HelR is a helicase-like protein that protects RNA polymerase from rifamycin antibiotics	160
INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II	159
You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion	159
Mitochondria: A “pacemaker” for species-specific development	154
Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions	152
A DNA helicase remodeling proteins: How DNA-protein crosslink repair unfolds via FANCJ	148
Meet the authors: Meiling Wang, Wenjing Li, and Weixing Zhao	146
S6K1 Regulates GSK3 under Conditions of mTOR-Dependent Feedback Inhibition of Akt	142
Gene architecture directs splicing outcome in separate nuclear spatial regions	136
SLC4A7 and mTORC1 raise nucleotide synthesis with bicarbonate	135
Altered nucleocytoplasmic export of adenosine-rich circRNAs by PABPC1 contributes to neuronal function	134
The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs	134
Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain	133
Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes	133
TADs do not stay in the loop	128
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition	124
The molecular basis of tRNA selectivity by human pseudouridine synthase 3	124
Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses	122
POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps	120
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules	116
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs	116
Mitochondrial protein transport: Versatility of translocases and mechanisms	115
DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production	115
Silent silencers: Leave no trace	112
Using SPIDRs to map the RNA-protein web	111
A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization	110
A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis	110
ZC3H14 facilitates backsplicing by binding to exon-intron boundary and 3′ UTR	110
Meet the authors: Emily R. Feierman and Erica Korb	110
The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism	107
Targeted citrullination enables p53 binding to non-canonical sites	107
Putative looping factor ZNF143/ZFP143 is an essential transcriptional regulator with no looping function	106
Structural basis for promoter recognition and transcription factor binding and release in human mitochondria	106
Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome	106
Cryo-EM reveals open and closed Asgard chromatin assemblies	105
Structural basis for product specificities of MLL family methyltransferases	105
IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance	104
Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity	104
Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2	104
POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells	102
ATR promotes clearance of damaged DNA and damaged cells by rupturing micronuclei	102
Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin	100
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate	100
Tuning insulin receptor signaling using de novo-designed agonists	99
Filament formation activates protease and ring nuclease activities of CRISPR Lon-SAVED	99
Dual allosteric modulation of voltage and calcium sensitivities of the Slo1-LRRC channel complex	98

The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress	98
Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag	98
Are nanopore technologies ready for the proteomic challenge primetime?	97
NLRP12 senses heme and PAMPs to drive necrotic cell death and inflammation	96
Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination	96
Bacterial ligases reveal fundamental principles of polyubiquitin specificity	95
Mycobacterium abscessus HelR interacts with RNA polymerase to confer intrinsic rifamycin resistance	94
A new chromatin flavor to cap chromosomes: Where structure, function, and evolution meet	94
Meet the authors: Irene Beusch and Hiten Madhani	92
Introducing new group leaders: Wen Zhou	91
A domain of all trades: The enzymatic versatility of the NiRAN domain	91
Structural snapshots of R-loop formation by a type I-C CRISPR Cascade	91
Senescence suppresses the integrated stress response and activates a stress-remodeled secretory phenotype	90
FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress	90
Universal features of Nsp1-mediated translational shutdown by coronaviruses	89
A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells	89
Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma	89