Nature Neuroscience

Article	Citations
Salty licorice taste receptor	706
Non-REM sleep substates separate old and new memories	585
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	416
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	339
A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease	320
Alcohol’s necessary accessory	297
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development	287
Neural basis of anticipation and premature impulsive action in the frontal cortex	268
Author Correction: Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development	259
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	252
Computational complexity drives sustained deliberation	250
Author Correction: Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas	249
Amyloid-β-driven glymphatic dysfunction in Alzheimer’s disease model mice is driven by Ca2+-mediated increases in astrocytic cholesterol	237
Daily feeding entrains hunger-sensing neurons	227
Climbing fibers provide essential instructive signals for associative learning	225
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	225
The choreography of cerebral vasculature development	222
A hippocampal ‘sharp-wave sleep’ state that is dissociable from cortical sleep	221
Implementation and validation of single-cell genomics experiments in neuroscience	202
Pervasive environmental chemicals impair oligodendrocyte development	201
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	199
Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape	198
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	191
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	191
Differential replay of reward and punishment paths predicts approach and avoidance	191

Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	177
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	172
Intracellular chloride regulation mediates local sleep pressure in the cortex	172
Neural basis of concurrent deliberation toward a choice and confidence judgment	172
Neurons in the caudal ventrolateral medulla mediate descending pain control	167
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	162
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	161
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	157
A prefrontal cortex map based on single-neuron activity	152
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics	147
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	147
Computational strategies for deliberative thought	145
Guest star in OCD	145
COVID-19 and brain aging	142
How cancer and cortex collude	141
Lessons from resilience	139
Glioblastoma–neuron networks	139
Negative self-experiences shape responses to others’ emotional states	132
An organoid biobank for neurodevelopmental disorders	129
Widespread brain–body integration during changes of arousal	129
Marc G. Caron (1946–2022)	129
The developmental emergence of reliable cortical representations	128
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	128
A neural mechanism for conserved value computations integrating information and rewards	125
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	125
TDP-43 loss induces cryptic polyadenylation in ALS/FTD	125
CRISPRi screening in cultured human astrocytes uncovers distal enhancers controlling genes dysregulated in Alzheimer’s disease	124
Neuroimmune interferon signals sustain arthritis pain	123
Activity map of a cortico-cerebellar loop underlying motor planning	121
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	120
Astrocytes make room for microglia	120
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	120
Screening for photoreceptor survival	120
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	118
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	118
Adult-born dentate granule cells promote hippocampal population sparsity	118
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	118
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	118
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing	116
Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD	115
Aversion crosses over	114
Psychedelic research must be grounded in pharmacology	114
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease	113
A European perspective on structural barriers to women’s career progression in neuroscience	113
Spatial proteomic analysis in human Alzheimer’s disease brains enables identification of microenvironment-dependent microglial cell states	112
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	112
Aging and injury drive neuronal senescence in the dorsal root ganglia	110
Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy	110
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	108
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	106

Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	105
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes	105
In conversation with Corey Harwell	104
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	104
Cerebellar organoids get active	102
Translation for transmission	102
Real control in virtual rats	101
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	101
Flipping APOE to reverse Alzheimer’s disease traits	100
Commensals boost nerve regeneration	99
Big data for classifying ASD	98
Comparing primate cerebellums	98
Chronic brain recordings reveal objective biomarkers of chronic pain	98
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	97
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	97
Facial expressions in mice reveal latent cognitive variables and their neural correlates	97
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging	96
Dynamics of mature myelin	96
Increased neural excitability and glioma synaptic activity drives glioma proliferation in human cortex	95
Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms	93
Neuronal tuning aligns dynamically with object and texture manifolds across the visual hierarchy	92
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	92
A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging	91
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	91
Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery	91
How to build a cognitive map	90
In conversation with Carla Shatz	90
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	90
AI predicts risk of mental health disorders	90
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	89
Gene programs driving cortical neuron specifications	89
Publisher Correction: Hormonal milieu influences whole-brain structural dynamics across the menstrual cycle using dense sampling in multiple individuals	88
Author Correction: Autoimmune neuroinflammation leads to neuronal death via MIF nuclease-mediated parthanatos	87
UBQLN2 links proteotoxicity with lipid metabolism in neurodegeneration	87
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement	87
From pain to brain	86
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	86
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	86
Using temperature to analyze the neural basis of a time-based decision	86
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	85
Considering biological limitations of lesion network mapping	85
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	84
How collaboration between bioethicists and neuroscientists can advance research	84
Reply to: A curious concept of CNS clearance	84
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	83
A fragile imbalance	83
Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells	82
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	81
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	81
Thalamus-driven functional populations in frontal cortex support decision-making	80
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	79
TGFβ signaling mediates microglial resilience to spatiotemporally restricted myelin degeneration	78
Charting brain morphology in international healthy and neurological populations	77
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	77
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	77
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	76
Semantic reconstruction of continuous language from non-invasive brain recordings	76
Gonads drive the brain	75
Complex topology meets simple statistics	75
Natural language instructions induce compositional generalization in networks of neurons	75
(Lost) gut feeling	75
Rapid motor skill adjustment is associated with population-level modulation of cerebellar error signals	74
In conversation with Fernando de Castro Soubriet	74
The cell-type underpinnings of the human functional cortical connectome	73
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	73
Freezing forgetting in C. elegans to extend memory retention	73
Estrogen dominance drives distinct patterns of brain plasticity	73
Sleep cycles process memories	73
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	72
Restoring sensation to prosthetics	72
Liver-derived exercise factor boosts brain vasculature	72
Mapping deep brain stimulation-modulated circuits via precision neuroimaging	72
TDP-43 loss brings RNA to a twist ending	71
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	71
A couple of couplings	71
Large-scale high-density brain-wide neural recording in nonhuman primates	71
Spatially clustered neurons in the bat midbrain encode vocalization categories	71
Base barrier cells provide compartmentalization of choroid plexus, brain and CSF	70
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	70
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	70

Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation	70
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	69
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	69
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	68
Neurogenic–angiogenic synchrony via lactate	68
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	67
A. D. (Bud) Craig, Jr. (1951–2023)	67
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	67
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	66
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	65
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	65
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	65
Anorexia nervosa microbiota	63
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	62
A very sexy circuit	62
The eyes have it	62
Salience in the raphe	62
Endocannabinoid protection of the brain vasculature leads to stress resilience	62
A common voice for neural data	62
Resilient cortical maps	61
AI beats neuroscientists’ predictions	61
Author Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain	60
Stress and autophagy	60
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	60
When protein turns toxic	60
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	60
Updating the striatal–pallidal wiring diagram	59
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	59
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	59
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	58
Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning	58
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	58
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	57
Corticothalamic communication for action coordination in a skilled motor behavior	57
High-precision mapping reveals the structure of odor coding in the human brain	57
Persistent interferon signaling causes sensory neuron plasticity and pain before and during arthritis	57
Cerebellar associative learning underlies skilled reach adaptation	57
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	56
The role of the lateral orbitofrontal cortex in creating cognitive maps	56
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	56
Control and recalibration of path integration in place cells using optic flow	56
Convergent information flows explain recurring firing patterns in cerebral cortex	55
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	55
Blood-to-brain communication in aging and rejuvenation	55
Gradients of neurotransmitter receptor expression in the macaque cortex	55
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	55
Propagation of neuronal micronuclei regulates microglial characteristics	55
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	54
In conversation with Aniruddha Das	54
Place fields illuminated	54
Blood proteins control microglia	54
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	53
Altruism and social rewards	53
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	53
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	53
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	53
Lewy body disease can spread via two distinct body-first routes	53
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	52
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning	52
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	52
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes	52
The prefrontal cortex controls memory organization in the hippocampus	52
A distinct hypothalamus–habenula circuit governs risk preference	52
Tirzepatide affects NAc activity and food preoccupation	52
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	51
Leveraging insights from neuroscience to build adaptive artificial intelligence	51
Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS	51
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	51
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	50
Value dynamics affect choice preparation during decision-making	50
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	50
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	50
Multilevel visual motion opponency in Drosophila	49
Twenty-five years of Nature Neuroscience	49
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	49
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	49
Lack of myelin improves axon survival in inflammatory lesions in the CNS	49
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	49
A unifying theory explains seemingly contradictory biases in perceptual estimation	49
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	49
A cholinergic auditory pathway	49
Reducing publication bias with Registered Reports	49
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	48
The stop and go of glymphatic flow	48
Together but opposites in reward	48
Functionally diverse human insular architecture with memory-related hippocampal interactions	48
Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits	47
Parallel gut-to-brain pathways orchestrate feeding behaviors	47
Author Correction: A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function	47
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates	47
Microglia RANK as fertility regulators	47
Prefrontal engrams of long-term fear memory perpetuate pain perception	47
Author Correction: Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories	47
AI predicts how brain injuries disrupt consciousness — and how to restore it once it’s disordered	47
Orexin neurons track temporal features of blood glucose in behaving mice	47