Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	527
Salty licorice taste receptor	495
Non-REM sleep substates separate old and new memories	421
Alcohol’s necessary accessory	410
Neural basis of anticipation and premature impulsive action in the frontal cortex	392
Differential replay of reward and punishment paths predicts approach and avoidance	327
Neurons in the caudal ventrolateral medulla mediate descending pain control	324
Implementation and validation of single-cell genomics experiments in neuroscience	317
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	296
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics	262
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	251
Intracellular chloride regulation mediates local sleep pressure in the cortex	240
Computational complexity drives sustained deliberation	223
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy	221
Daily feeding entrains hunger-sensing neurons	215
Pervasive environmental chemicals impair oligodendrocyte development	215
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	213
Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape	211
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	208
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development	194
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	193
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	192
Climbing fibers provide essential instructive signals for associative learning	191
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	188
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	188

Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	185
Genetic variants associated with longitudinal changes in brain structure across the lifespan	174
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	174
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	174
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	173
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	172
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	170
Guest star in OCD	168
Computational strategies for deliberative thought	165
Organizing principles of the prefrontal cortex from a single-neuron projectome	152
COVID-19 and brain aging	152
How cancer and cortex collude	146
Lessons from resilience	145
Retraction Note: From neurons to microglia, with complements	144
Glioblastoma–neuron networks	142
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	140
Negative self-experiences shape responses to others’ emotional states	140
Marc G. Caron (1946–2022)	139
Aversion crosses over	136
Widespread brain–body integration during changes of arousal	135
A European perspective on structural barriers to women’s career progression in neuroscience	131
Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD	131
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	130
Astrocytes make room for microglia	128
The developmental emergence of reliable cortical representations	128
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing	126
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes	125
Activity map of a cortico-cerebellar loop underlying motor planning	122
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	122
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	122
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	122
A neural mechanism for conserved value computations integrating information and rewards	121
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease	118
TDP-43 loss induces cryptic polyadenylation in ALS/FTD	115
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	114
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	113
Adult-born dentate granule cells promote hippocampal population sparsity	113
Gender and geographical disparity in editorial boards of journals in psychology and neuroscience	112
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	111
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	109
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	107
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	107
A synergistic core for human brain evolution and cognition	107
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	104
Aging and injury drive neuronal senescence in the dorsal root ganglia	102
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	102
Common and stimulus-type-specific brain representations of negative affect	101
In conversation with Corey Harwell	100
Translation for transmission	99
Cerebellar organoids get active	98

Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	98
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging	97
Real control in virtual rats	97
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	96
Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery	96
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	96
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	95
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	94
A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging	93
Chronic brain recordings reveal objective biomarkers of chronic pain	93
Big data for classifying ASD	93
Facial expressions in mice reveal latent cognitive variables and their neural correlates	92
Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	92
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state	92
Dynamics of mature myelin	92
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	91
Microglia contribute to the propagation of Aβ into unaffected brain tissue	89
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	89
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	87
How to build a cognitive map	87
Commensals boost nerve regeneration	87
A fragile imbalance	86
In conversation with Carla Shatz	85
Personalized EES for SCI	85
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	84
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	84
AI predicts risk of mental health disorders	83
Gene programs driving cortical neuron specifications	83
Re-conceptualizing domains in neuroscience, hopes and utopias aside	83
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	82
Using temperature to analyze the neural basis of a time-based decision	82
Reply to: A curious concept of CNS clearance	81
From pain to brain	80
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement	80
Natural language instructions induce compositional generalization in networks of neurons	80
How the brain regulates its own immune system	79
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	79
Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells	79
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	78
Thalamus-driven functional populations in frontal cortex support decision-making	78
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	78
Semantic reconstruction of continuous language from non-invasive brain recordings	77
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	77
How collaboration between bioethicists and neuroscientists can advance research	77
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	76
Shared computational principles for language processing in humans and deep language models	76
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	75
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	75
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways	74
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	74
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	73
(Lost) gut feeling	73
Complex topology meets simple statistics	73
In conversation with Fernando de Castro Soubriet	72
Gonads drive the brain	72
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	72
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	71
Refining the negative into general and specific	71
Sleep cycles process memories	70
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	70
Silencing gut CCK cells alters gut reaction to sugar	70
TDP-43 loss brings RNA to a twist ending	70
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	69
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	69
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	69
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains	69
The cell-type underpinnings of the human functional cortical connectome	69
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	69
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	68
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus	68
Neurogenic–angiogenic synchrony via lactate	67
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	67
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	66
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	65
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	65
A. D. (Bud) Craig, Jr. (1951–2023)	65
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	65
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	64
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	64
Restoring sensation to prosthetics	64

Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	64
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)	64
Spatially clustered neurons in the bat midbrain encode vocalization categories	63
Large-scale high-density brain-wide neural recording in nonhuman primates	62
Anorexia nervosa microbiota	62
Thalamic subnetworks as units of function	62
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error	62
A very sexy circuit	61
Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans	61
Endocannabinoid protection of the brain vasculature leads to stress resilience	61
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	61
A common voice for neural data	61
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	61
AI beats neuroscientists’ predictions	61
The eyes have it	61
Salience in the raphe	61
Resilient cortical maps	61
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	60
Stress and autophagy	60
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	60
Magnetic resonance-based eye tracking using deep neural networks	59
Author Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain	59
Gradients of neurotransmitter receptor expression in the macaque cortex	59
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	58
Blood-to-brain communication in aging and rejuvenation	58
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	57
Cortical interneurons in autism	57
The role of the lateral orbitofrontal cortex in creating cognitive maps	57
Control and recalibration of path integration in place cells using optic flow	57
Updating the striatal–pallidal wiring diagram	57
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence	57
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	56
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	56
High-precision mapping reveals the structure of odor coding in the human brain	56
Propagation of neuronal micronuclei regulates microglial characteristics	56
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	55
Adult neurogenesis is altered in neurodegenerative disease	55
Cerebellar associative learning underlies skilled reach adaptation	55
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	55
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	54
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	54
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	54
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	54
Blood proteins control microglia	54
Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning	54
In conversation with Aniruddha Das	53
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	52
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	52
Place fields illuminated	52
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	52
Puberty reverses sex differences in learning	51
Altruism and social rewards	51
Multilevel visual motion opponency in Drosophila	50
Lewy body disease can spread via two distinct body-first routes	50
Reducing publication bias with Registered Reports	50
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	50
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	50
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	49
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	49
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	49
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	49
A unifying theory explains seemingly contradictory biases in perceptual estimation	48
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	48
A distinct hypothalamus–habenula circuit governs risk preference	48
Value dynamics affect choice preparation during decision-making	48
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	48
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning	48
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes	48
Lack of myelin improves axon survival in inflammatory lesions in the CNS	47
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	47
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	47
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	47
Adolescent sleep molds adult social preferences	47
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	47
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	47
Together but opposites in reward	46
A cholinergic auditory pathway	46
Twenty-five years of Nature Neuroscience	46
The stop and go of glymphatic flow	45
Impaired gut barrier affects microglia health	45
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	45
Integrated cardio-behavioral responses to threat define defensive states	45
Functionally diverse human insular architecture with memory-related hippocampal interactions	44
Norepinephrine links astrocytic activity to regulation of cortical state	44
Orexin neurons track temporal features of blood glucose in behaving mice	44
A motor association area in the depths of the central sulcus	44
Author Correction: A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function	44
Parallel gut-to-brain pathways orchestrate feeding behaviors	44
Corticospinal populations broadcast complex motor signals to coordinated spinal and striatal circuits	43
Single-neuron projectome of mouse prefrontal cortex	43
Prefrontal engrams of long-term fear memory perpetuate pain perception	43
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence	42
Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia	42
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates	42
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine	42