Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	432
Salty licorice taste receptor	425
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	420
Non-REM sleep substates separate old and new memories	392
Alcohol’s necessary accessory	358
Maybe too much of a good thing in gene therapy	342
Neural basis of anticipation and premature impulsive action in the frontal cortex	290
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	268
Neurons in the caudal ventrolateral medulla mediate descending pain control	265
Daily feeding entrains hunger-sensing neurons	264
Implementation and validation of single-cell genomics experiments in neuroscience	252
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	232
Computational complexity drives sustained deliberation	215
Pervasive environmental chemicals impair oligodendrocyte development	214
Differential replay of reward and punishment paths predicts approach and avoidance	212
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	187
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	187
Climbing fibers provide essential instructive signals for associative learning	186
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy	185
Intracellular chloride regulation mediates local sleep pressure in the cortex	184
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	184
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	177
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	175
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	174
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	170

Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	163
Genetic variants associated with longitudinal changes in brain structure across the lifespan	161
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	161
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways	158
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	156
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	155
Revisiting the neurovascular unit	155
Guest star in OCD	153
Computational strategies for deliberative thought	151
COVID-19 and brain aging	149
Organizing principles of the prefrontal cortex from a single-neuron projectome	149
Lessons from resilience	145
How cancer and cortex collude	145
Widespread brain–body integration during changes of arousal	140
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	139
Remembering Stephen T. Warren, a pillar of neurogenetics (1953–2021)	137
A European perspective on structural barriers to women’s career progression in neuroscience	137
Marc G. Caron (1946–2022)	135
Aversion crosses over	134
Retraction Note: From neurons to microglia, with complements	129
Glioblastoma–neuron networks	127
Negative self-experiences shape responses to others’ emotional states	126
Aging and injury drive neuronal senescence in the dorsal root ganglia	126
A role for the cortex in sleep–wake regulation	125
The developmental emergence of reliable cortical representations	122
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	120
A neural mechanism for conserved value computations integrating information and rewards	120
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	119
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	118
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	117
Adult-born dentate granule cells promote hippocampal population sparsity	117
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	113
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	113
Common and stimulus-type-specific brain representations of negative affect	113
Gender and geographical disparity in editorial boards of journals in psychology and neuroscience	113
A synergistic core for human brain evolution and cognition	112
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	110
A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging	108
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	106
Activity map of a cortico-cerebellar loop underlying motor planning	105
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	104
Dopamine drives mating via cAMP	103
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	103
In conversation with Corey Harwell	102
Translation for transmission	102
Cerebellar organoids get active	102
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	102
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	101
Real control in virtual rats	101
Commensals boost nerve regeneration	99

Chronic brain recordings reveal objective biomarkers of chronic pain	99
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	96
Causal reductionism and causal structures	95
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	94
Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time	92
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement	91
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	91
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	91
Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	90
How to build a cognitive map	90
Microglia contribute to the propagation of Aβ into unaffected brain tissue	89
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state	89
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	89
Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders	89
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	89
Dynamics of mature myelin	87
In conversation with Carla Shatz	86
Personalized EES for SCI	86
A fragile imbalance	86
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	85
Microglia set the pace for tau spread	84
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	84
AI predicts risk of mental health disorders	83
Natural language instructions induce compositional generalization in networks of neurons	82
From pain to brain	82
Reply to: A curious concept of CNS clearance	82
How collaboration between bioethicists and neuroscientists can advance research	82
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	80
How the brain regulates its own immune system	80
Gene programs driving cortical neuron specifications	80
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	79
Using temperature to analyze the neural basis of a time-based decision	78
Re-conceptualizing domains in neuroscience, hopes and utopias aside	78
Thalamus-driven functional populations in frontal cortex support decision-making	78
Semantic reconstruction of continuous language from non-invasive brain recordings	77
Shared computational principles for language processing in humans and deep language models	77
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	76
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	76
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	75
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	74
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	74
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways	73
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	73
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	73
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	73
(Lost) gut feeling	73
Complex topology meets simple statistics	72
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	71
Gonads drive the brain	71
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	70
In conversation with Fernando de Castro Soubriet	70
Refining the negative into general and specific	70
Restoring sensation to prosthetics	70
Author Correction: Disordered grids in the third dimension	69
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	69
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	69
Spatially clustered neurons in the bat midbrain encode vocalization categories	68
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	68
Silencing gut CCK cells alters gut reaction to sugar	68
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	68
Neurogenic–angiogenic synchrony via lactate	67
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)	66
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	66
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	66
Divergent projections of the paraventricular nucleus of the thalamus mediate the selection of passive and active defensive behaviors	65
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	65
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus	65
The cell-type underpinnings of the human functional cortical connectome	65
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	64
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains	64
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error	64
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	64
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	64
A. D. (Bud) Craig, Jr. (1951–2023)	64
Thalamic subnetworks as units of function	62
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	62
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	61
Polygenic risk scores do not add value for predicting schizophrenia outcomes	61
Salience in the raphe	61
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	60

Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans	60
A very sexy circuit	60
Anorexia nervosa microbiota	60
Adult neurogenesis is altered in neurodegenerative disease	59
The eyes have it	59
A common voice for neural data	59
AI beats neuroscientists’ predictions	58
Endocannabinoid protection of the brain vasculature leads to stress resilience	58
Propagation of neuronal micronuclei regulates microglial characteristics	58
Updating the striatal–pallidal wiring diagram	58
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	58
Stress and autophagy	57
Magnetic resonance-based eye tracking using deep neural networks	57
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	57
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	57
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	57
Serotonin and addiction prevention	57
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	57
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	56
Gradients of neurotransmitter receptor expression in the macaque cortex	56
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	56
High-precision mapping reveals the structure of odor coding in the human brain	56
Cerebellar associative learning underlies skilled reach adaptation	55
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	54
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	54
The role of the lateral orbitofrontal cortex in creating cognitive maps	54
Blood-to-brain communication in aging and rejuvenation	53
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	52
Control and recalibration of path integration in place cells using optic flow	52
Blood proteins control microglia	52
Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility	52
Cortical interneurons in autism	52
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence	52
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	52
In conversation with Aniruddha Das	52
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	51
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	51
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	51
Lewy body disease can spread via two distinct body-first routes	50
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	50
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	50
Puberty reverses sex differences in learning	50
Altruism and social rewards	50
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	50
Place fields illuminated	50
Reducing publication bias with Registered Reports	49
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	49
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	49
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	49
Exome sequencing in obsessive–compulsive disorder reveals a burden of rare damaging coding variants	49
Value dynamics affect choice preparation during decision-making	48
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	48
Multilevel visual motion opponency in Drosophila	48
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	48
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	47
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	47
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	46
Precisely timed theta oscillations are selectively required during the encoding phase of memory	46
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	46
A unifying theory explains seemingly contradictory biases in perceptual estimation	46
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	46
Twenty-five years of Nature Neuroscience	45
A cholinergic auditory pathway	45
Lack of myelin improves axon survival in inflammatory lesions in the CNS	45
Adolescent sleep molds adult social preferences	45
A distinct hypothalamus–habenula circuit governs risk preference	45
Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits	45
Impaired gut barrier affects microglia health	45
Together but opposites in reward	44
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates	44
Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler	44
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	44
Integrated cardio-behavioral responses to threat define defensive states	43
The stop and go of glymphatic flow	43
Prefrontal engrams of long-term fear memory perpetuate pain perception	43
Norepinephrine links astrocytic activity to regulation of cortical state	43
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine	42
Causal role for the primate superior colliculus in the computation of evidence for perceptual decisions	42
Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia	42
A motor association area in the depths of the central sulcus	42
Orexin neurons track temporal features of blood glucose in behaving mice	42
Formalizing planning and information search in naturalistic decision-making	41
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage	41
Parallel gut-to-brain pathways orchestrate feeding behaviors	41
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence	41
Corticospinal populations broadcast complex motor signals to coordinated spinal and striatal circuits	41
Single-neuron projectome of mouse prefrontal cortex	41
Humans can intermittently respond to verbal stimuli when sleeping	40
Sensory and behavioral modulation of thalamic head-direction cells	40
Do all norepinephrine surges disrupt sleep?	40
In conversation with Sonia Mayoral	40
Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction	40
It’s go time	40
A basic role for glia in sleep homeostasis	39
The kainate receptor GluK2 mediates cold sensing in mice	39