Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	465
Salty licorice taste receptor	450
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	442
Non-REM sleep substates separate old and new memories	438
Alcohol’s necessary accessory	382
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	376
Neural basis of anticipation and premature impulsive action in the frontal cortex	328
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	290
Daily feeding entrains hunger-sensing neurons	288
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	278
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	276
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	246
Neurons in the caudal ventrolateral medulla mediate descending pain control	230
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy	222
Differential replay of reward and punishment paths predicts approach and avoidance	217
Pervasive environmental chemicals impair oligodendrocyte development	201
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	201
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	199
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	198
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	194
Computational complexity drives sustained deliberation	193
Intracellular chloride regulation mediates local sleep pressure in the cortex	192
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	188
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	180
Implementation and validation of single-cell genomics experiments in neuroscience	178

Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	177
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways	177
Genetic variants associated with longitudinal changes in brain structure across the lifespan	174
Climbing fibers provide essential instructive signals for associative learning	169
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	169
Revisiting the neurovascular unit	164
Guest star in OCD	161
Computational strategies for deliberative thought	160
COVID-19 and brain aging	157
Organizing principles of the prefrontal cortex from a single-neuron projectome	157
How cancer and cortex collude	156
Lessons from resilience	151
Widespread brain–body integration during changes of arousal	146
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	142
A European perspective on structural barriers to women’s career progression in neuroscience	141
Remembering Stephen T. Warren, a pillar of neurogenetics (1953–2021)	140
Marc G. Caron (1946–2022)	138
Retraction Note: From neurons to microglia, with complements	134
Aversion crosses over	134
Glioblastoma–neuron networks	132
Negative self-experiences shape responses to others’ emotional states	132
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	131
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	131
Gender and geographical disparity in editorial boards of journals in psychology and neuroscience	130
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	128
Activity map of a cortico-cerebellar loop underlying motor planning	127
The developmental emergence of reliable cortical representations	127
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	126
Aging and injury drive neuronal senescence in the dorsal root ganglia	123
A neural mechanism for conserved value computations integrating information and rewards	121
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	121
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	120
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	119
A synergistic core for human brain evolution and cognition	116
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	114
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	114
A role for the cortex in sleep–wake regulation	113
A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging	112
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	111
Adult-born dentate granule cells promote hippocampal population sparsity	111
Common and stimulus-type-specific brain representations of negative affect	110
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	110
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	108
Dopamine drives mating via cAMP	108
Translation for transmission	107
Cerebellar organoids get active	107
Causal reductionism and causal structures	106
In conversation with Corey Harwell	106
Microglia contribute to the propagation of Aβ into unaffected brain tissue	105
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state	105

Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	100
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	100
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	99
How to build a cognitive map	99
Real control in virtual rats	97
Chronic brain recordings reveal objective biomarkers of chronic pain	97
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	97
Commensals boost nerve regeneration	96
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	95
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	94
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	92
Dynamics of mature myelin	92
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	91
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	91
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement	90
A fragile imbalance	89
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	88
In conversation with Carla Shatz	88
Personalized EES for SCI	88
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	87
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	86
Microglia set the pace for tau spread	86
How collaboration between bioethicists and neuroscientists can advance research	85
How the brain regulates its own immune system	85
AI predicts risk of mental health disorders	84
Reply to: A curious concept of CNS clearance	84
Gene programs driving cortical neuron specifications	83
From pain to brain	83
Re-conceptualizing domains in neuroscience, hopes and utopias aside	82
Thalamus-driven functional populations in frontal cortex support decision-making	81
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	81
Using temperature to analyze the neural basis of a time-based decision	80
Natural language instructions induce compositional generalization in networks of neurons	79
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	79
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	78
Shared computational principles for language processing in humans and deep language models	78
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	78
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	78
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	77
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways	77
Semantic reconstruction of continuous language from non-invasive brain recordings	77
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	77
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	77
(Lost) gut feeling	76
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	76
In conversation with Fernando de Castro Soubriet	75
Gonads drive the brain	75
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	75
Complex topology meets simple statistics	75
Restoring sensation to prosthetics	74
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error	73
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	73
Divergent projections of the paraventricular nucleus of the thalamus mediate the selection of passive and active defensive behaviors	72
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus	72
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	72
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	71
Refining the negative into general and specific	71
Large-scale high-density brain-wide neural recording in nonhuman primates	70
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	70
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains	70
Author Correction: Disordered grids in the third dimension	70
Spatially clustered neurons in the bat midbrain encode vocalization categories	69
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	69
Silencing gut CCK cells alters gut reaction to sugar	69
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	69
Sleep cycles process memories	69
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	68
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	67
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	67
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	66
Neurogenic–angiogenic synchrony via lactate	66
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	66
A. D. (Bud) Craig, Jr. (1951–2023)	66
Thalamic subnetworks as units of function	65
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	65
The cell-type underpinnings of the human functional cortical connectome	64
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	64
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)	63
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	63
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	63

Polygenic risk scores do not add value for predicting schizophrenia outcomes	62
Anorexia nervosa microbiota	62
Salience in the raphe	62
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	62
Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans	61
A very sexy circuit	61
A common voice for neural data	61
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	60
The eyes have it	60
Propagation of neuronal micronuclei regulates microglial characteristics	60
Endocannabinoid protection of the brain vasculature leads to stress resilience	59
AI beats neuroscientists’ predictions	59
Control and recalibration of path integration in place cells using optic flow	58
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	58
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	58
Stress and autophagy	58
Serotonin and addiction prevention	58
High-precision mapping reveals the structure of odor coding in the human brain	57
Resilient cortical maps	57
Cerebellar associative learning underlies skilled reach adaptation	57
Updating the striatal–pallidal wiring diagram	57
Adult neurogenesis is altered in neurodegenerative disease	57
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	56
Magnetic resonance-based eye tracking using deep neural networks	56
The role of the lateral orbitofrontal cortex in creating cognitive maps	56
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	56
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence	55
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	55
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	55
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	55
Cortical interneurons in autism	54
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	54
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	54
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	53
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	53
Gradients of neurotransmitter receptor expression in the macaque cortex	53
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	53
Blood-to-brain communication in aging and rejuvenation	53
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	52
In conversation with Aniruddha Das	52
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	52
Blood proteins control microglia	52
Puberty reverses sex differences in learning	51
Place fields illuminated	51
Altruism and social rewards	51
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	51
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	50
Lewy body disease can spread via two distinct body-first routes	50
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	50
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	50
Reducing publication bias with Registered Reports	49
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	49
A unifying theory explains seemingly contradictory biases in perceptual estimation	49
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	49
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	49
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	49
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	48
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	48
A distinct hypothalamus–habenula circuit governs risk preference	48
Multilevel visual motion opponency in Drosophila	48
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	48
Twenty-five years of Nature Neuroscience	47
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	47
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	47
Lack of myelin improves axon survival in inflammatory lesions in the CNS	47
Value dynamics affect choice preparation during decision-making	47
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	47
Precisely timed theta oscillations are selectively required during the encoding phase of memory	47
Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits	45
A cholinergic auditory pathway	45
Impaired gut barrier affects microglia health	45
Adolescent sleep molds adult social preferences	45
The stop and go of glymphatic flow	44
A motor association area in the depths of the central sulcus	44
Together but opposites in reward	44
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	44
Integrated cardio-behavioral responses to threat define defensive states	43
Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler	43
Parallel gut-to-brain pathways orchestrate feeding behaviors	43
Functionally diverse human insular architecture with memory-related hippocampal interactions	43
Prefrontal engrams of long-term fear memory perpetuate pain perception	43
Orexin neurons track temporal features of blood glucose in behaving mice	43
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence	42
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates	42
Corticospinal populations broadcast complex motor signals to coordinated spinal and striatal circuits	42
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage	42
Norepinephrine links astrocytic activity to regulation of cortical state	42
Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia	42
Single-neuron projectome of mouse prefrontal cortex	42
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine	41
Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction	41
It’s go time	41
Humans can intermittently respond to verbal stimuli when sleeping	41
Do all norepinephrine surges disrupt sleep?	41
In conversation with Sonia Mayoral	40