Nature Neuroscience

Article	Citations
Salty licorice taste receptor	769
Non-REM sleep substates separate old and new memories	446
A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease	370
Alcohol’s necessary accessory	337
Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape	323
Author Correction: Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development	304
Computational complexity drives sustained deliberation	284
Author Correction: Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas	277
Daily feeding entrains hunger-sensing neurons	277
The choreography of cerebral vasculature development	274
Implementation and validation of single-cell genomics experiments in neuroscience	266
Neural basis of anticipation and premature impulsive action in the frontal cortex	260
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	254
A hippocampal ‘sharp-wave sleep’ state that is dissociable from cortical sleep	240
Neural basis of concurrent deliberation toward a choice and confidence judgment	238
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	217
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development	215
Differential replay of reward and punishment paths predicts approach and avoidance	211
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	210
Amyloid-β-driven glymphatic dysfunction in Alzheimer’s disease model mice is driven by Ca2+-mediated increases in astrocytic cholesterol	206
A prefrontal cortex map based on single-neuron activity	197
Neurons in the caudal ventrolateral medulla mediate descending pain control	193
Pervasive environmental chemicals impair oligodendrocyte development	181
Climbing fibers provide essential instructive signals for associative learning	176
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics	175

Hippocampus shapes entorhinal cortical output through a direct feedback circuit	170
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	161
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	159
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	158
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	156
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	156
Intracellular chloride regulation mediates local sleep pressure in the cortex	152
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	149
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	146
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	145
Guest star in OCD	143
Computational strategies for deliberative thought	141
COVID-19 and brain aging	141
How cancer and cortex collude	140
Lessons from resilience	140
Negative self-experiences shape responses to others’ emotional states	139
Glioblastoma–neuron networks	139
An organoid biobank for neurodevelopmental disorders	138
Widespread brain–body integration during changes of arousal	136
Marc G. Caron (1946–2022)	136
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	135
Screening for photoreceptor survival	133
Astrocytes make room for microglia	130
Neuroimmune interferon signals sustain arthritis pain	130
Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD	128
Psychedelic research must be grounded in pharmacology	127
Aversion crosses over	126
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing	125
A European perspective on structural barriers to women’s career progression in neuroscience	125
The developmental emergence of reliable cortical representations	124
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	123
Replay of procedural memory is independent of the hippocampus	121
Adult-born dentate granule cells promote hippocampal population sparsity	121
Aging and injury drive neuronal senescence in the dorsal root ganglia	120
Spatial proteomic analysis in human Alzheimer’s disease brains enables identification of microenvironment-dependent microglial cell states	119
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	119
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	118
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	118
Activity map of a cortico-cerebellar loop underlying motor planning	117
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	116
Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice	115
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	114
CRISPRi screening in cultured human astrocytes uncovers distal enhancers controlling genes dysregulated in Alzheimer’s disease	113
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes	113
Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy	112
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	112
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease	112
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	111
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	110
A neural mechanism for conserved value computations integrating information and rewards	109

TDP-43 loss induces cryptic polyadenylation in ALS/FTD	108
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	108
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	108
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	107
In conversation with Corey Harwell	105
Translation for transmission	104
Cerebellar organoids get active	102
Real control in virtual rats	101
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	101
Publisher Correction: TGFβ signaling mediates microglial resilience to spatiotemporally restricted myelin degeneration	100
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	100
Chronic brain recordings reveal objective biomarkers of chronic pain	99
Neuronal tuning aligns dynamically with object and texture manifolds across the visual hierarchy	98
Flipping APOE to reverse Alzheimer’s disease traits	97
Big data for classifying ASD	97
Commensals boost nerve regeneration	96
Increased neural excitability and glioma synaptic activity drives glioma proliferation in human cortex	95
Comparing primate cerebellums	95
Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms	94
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	93
Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery	93
Facial expressions in mice reveal latent cognitive variables and their neural correlates	93
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	93
Dynamics of mature myelin	91
A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging	91
How to build a cognitive map	91
AI predicts risk of mental health disorders	90
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	90
In conversation with Carla Shatz	90
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging	90
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	89
Gene programs driving cortical neuron specifications	89
Publisher Correction: Hormonal milieu influences whole-brain structural dynamics across the menstrual cycle using dense sampling in multiple individuals	89
From pain to brain	88
Author Correction: Autoimmune neuroinflammation leads to neuronal death via MIF nuclease-mediated parthanatos	88
Considering biological limitations of lesion network mapping	87
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	87
Thalamus-driven functional populations in frontal cortex support decision-making	87
Cerebrovascular vulnerability and fibrosis in human brain aneurysms	85
TGFβ signaling mediates microglial resilience to spatiotemporally restricted myelin degeneration	84
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement	83
How collaboration between bioethicists and neuroscientists can advance research	83
Oxytocin promotes socially triggered cataplexy	83
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	82
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	82
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	82
UBQLN2 links proteotoxicity with lipid metabolism in neurodegeneration	81
Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells	81
Mitochondrial stress response drives microglial senescence	81
Using temperature to analyze the neural basis of a time-based decision	81
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	80
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	80
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	80
Reply to: A curious concept of CNS clearance	79
Charting brain morphology in international healthy and neurological populations	79
Semantic reconstruction of continuous language from non-invasive brain recordings	78
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	78
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	77
Complex topology meets simple statistics	77
Natural language instructions induce compositional generalization in networks of neurons	77
(Lost) gut feeling	77
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	77
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	76
In conversation with Fernando de Castro Soubriet	76
A. D. (Bud) Craig, Jr. (1951–2023)	75
Estrogen dominance drives distinct patterns of brain plasticity	75
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	75
Freezing forgetting in C. elegans to extend memory retention	74
Sleep cycles process memories	74
TDP-43 loss brings RNA to a twist ending	73
Liver-derived exercise factor boosts brain vasculature	73
A couple of couplings	73
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	72
Spatially clustered neurons in the bat midbrain encode vocalization categories	72
Mapping deep brain stimulation-modulated circuits via precision neuroimaging	72
Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation	71
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	70
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	70
Base barrier cells provide compartmentalization of choroid plexus, brain and CSF	70
Restoring sensation to prosthetics	70

Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	69
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	69
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	68
Author Correction: FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis	68
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	68
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	68
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	68
Large-scale high-density brain-wide neural recording in nonhuman primates	67
An activity-modulated transport route across myelin (TRAM) for motor-driven organelle transfer in oligodendrocytes	65
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	65
The cell-type underpinnings of the human functional cortical connectome	65
Rapid motor skill adjustment is associated with population-level modulation of cerebellar error signals	64
Salience in the raphe	63
A very sexy circuit	63
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	63
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	63
A common voice for neural data	63
Endocannabinoid protection of the brain vasculature leads to stress resilience	63
Anorexia nervosa microbiota	63
The eyes have it	63
Resilient cortical maps	62
AI beats neuroscientists’ predictions	62
When protein turns toxic	62
Stress and autophagy	61
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	61
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	61
Author Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain	61
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	61
Persistent interferon signaling causes sensory neuron plasticity and pain before and during arthritis	60
The hippocampus is listening	60
Cerebellar associative learning underlies skilled reach adaptation	60
Convergent information flows explain recurring firing patterns in cerebral cortex	60
Control and recalibration of path integration in place cells using optic flow	59
Updating the striatal–pallidal wiring diagram	59
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	59
Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning	59
Corticothalamic communication for action coordination in a skilled motor behavior	58
Propagation of neuronal micronuclei regulates microglial characteristics	58
Blood-to-brain communication in aging and rejuvenation	58
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	58
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	58
Gradients of neurotransmitter receptor expression in the macaque cortex	57
High-precision mapping reveals the structure of odor coding in the human brain	57
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	57
The role of the lateral orbitofrontal cortex in creating cognitive maps	57
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	56
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	56
Altruism and social rewards	56
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	56
Blood proteins control microglia	56
In conversation with Aniruddha Das	56
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	56
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	56
Place fields illuminated	56
Lewy body disease can spread via two distinct body-first routes	55
Multilevel visual motion opponency in Drosophila	55
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	55
Reducing publication bias with Registered Reports	55
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	55
Tirzepatide affects NAc activity and food preoccupation	55
Cell atlas of brain aneurysms reveals fibroblast–macrophage crosstalk	54
Leveraging insights from neuroscience to build adaptive artificial intelligence	54
Tryptamine from wake-active monoaminergic neurons regulates sleep homeostasis	54
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	53
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	53
A unifying theory explains seemingly contradictory biases in perceptual estimation	53
The prefrontal cortex controls memory organization in the hippocampus	53
DBS: from neuromodulation to neuroremodelling	53
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	52
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	52
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning	52
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	52
Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS	52
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	52
Aberrant tau accumulation caused by MAPT mutations induces early pathological changes in axonal transport that are rescued by p38α inhibition	52
Value dynamics affect choice preparation during decision-making	51
A distinct hypothalamus–habenula circuit governs risk preference	51
Focal astrocyte loss reveals nuclear translocation during lesion repopulation	51
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	51
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	50
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	50
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	50
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	50
Lack of myelin improves axon survival in inflammatory lesions in the CNS	50
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes	50
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	50
A cholinergic auditory pathway	50
Together but opposites in reward	49
Author Correction: A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function	49
Functionally diverse human insular architecture with memory-related hippocampal interactions	49
The stop and go of glymphatic flow	49
Author Correction: Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories	49
Twenty-five years of Nature Neuroscience	49
A motor association area in the depths of the central sulcus	49
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	48