Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	683
Salty licorice taste receptor	571
Non-REM sleep substates separate old and new memories	493
Daily feeding entrains hunger-sensing neurons	403
Neurons in the caudal ventrolateral medulla mediate descending pain control	330
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	315
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	285
A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease	281
Alcohol’s necessary accessory	273
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development	263
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	252
Neural basis of anticipation and premature impulsive action in the frontal cortex	246
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	242
Author Correction: Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development	242
Computational complexity drives sustained deliberation	232
Author Correction: Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas	221
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	218
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	217
Neural basis of concurrent deliberation toward a choice and confidence judgment	215
Differential replay of reward and punishment paths predicts approach and avoidance	214
Implementation and validation of single-cell genomics experiments in neuroscience	198
Amyloid-β-driven glymphatic dysfunction in Alzheimer’s disease model mice is driven by Ca2+-mediated increases in astrocytic cholesterol	194
A hippocampal ‘sharp-wave sleep’ state that is dissociable from cortical sleep	192
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	191
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	187

Pervasive environmental chemicals impair oligodendrocyte development	186
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	184
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	174
Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape	170
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	168
Intracellular chloride regulation mediates local sleep pressure in the cortex	167
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	162
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	161
Climbing fibers provide essential instructive signals for associative learning	159
A prefrontal cortex map based on single-neuron activity	153
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics	146
Guest star in OCD	145
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	145
Computational strategies for deliberative thought	144
COVID-19 and brain aging	143
How cancer and cortex collude	142
Glioblastoma–neuron networks	140
Lessons from resilience	140
Negative self-experiences shape responses to others’ emotional states	137
An organoid biobank for neurodevelopmental disorders	137
Marc G. Caron (1946–2022)	132
Widespread brain–body integration during changes of arousal	130
TDP-43 loss induces cryptic polyadenylation in ALS/FTD	128
The developmental emergence of reliable cortical representations	127
Aging and injury drive neuronal senescence in the dorsal root ganglia	126
Adult-born dentate granule cells promote hippocampal population sparsity	125
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	125
CRISPRi screening in cultured human astrocytes uncovers distal enhancers controlling genes dysregulated in Alzheimer’s disease	124
A neural mechanism for conserved value computations integrating information and rewards	124
Common and stimulus-type-specific brain representations of negative affect	124
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	123
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	122
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	121
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	120
A European perspective on structural barriers to women’s career progression in neuroscience	119
Astrocytes make room for microglia	119
Psychedelic research must be grounded in pharmacology	118
Aversion crosses over	118
Neuroimmune interferon signals sustain arthritis pain	116
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes	115
Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy	115
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	115
Activity map of a cortico-cerebellar loop underlying motor planning	114
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	112
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	112
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease	111
Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD	110
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing	110
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	110
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	109

Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	108
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	108
A synergistic core for human brain evolution and cognition	107
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	106
In conversation with Corey Harwell	106
Cerebellar organoids get active	104
Translation for transmission	104
Real control in virtual rats	103
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	103
Flipping APOE to reverse Alzheimer’s disease traits	102
Commensals boost nerve regeneration	101
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	100
Increased neural excitability and glioma synaptic activity drives glioma proliferation in human cortex	100
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	99
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	96
Neuronal tuning aligns dynamically with object and texture manifolds across the visual hierarchy	96
A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging	96
Big data for classifying ASD	96
Comparing primate cerebellums	96
Chronic brain recordings reveal objective biomarkers of chronic pain	95
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	93
Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms	93
Dynamics of mature myelin	93
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	92
Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery	92
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	92
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	92
Facial expressions in mice reveal latent cognitive variables and their neural correlates	91
How to build a cognitive map	90
Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	90
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging	90
A fragile imbalance	89
Gene programs driving cortical neuron specifications	88
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	88
AI predicts risk of mental health disorders	88
How the brain regulates its own immune system	88
In conversation with Carla Shatz	88
Natural language instructions induce compositional generalization in networks of neurons	87
Publisher Correction: Hormonal milieu influences whole-brain structural dynamics across the menstrual cycle using dense sampling in multiple individuals	87
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	86
Author Correction: Autoimmune neuroinflammation leads to neuronal death via MIF nuclease-mediated parthanatos	86
UBQLN2 links proteotoxicity with lipid metabolism in neurodegeneration	86
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement	84
From pain to brain	84
Reply to: A curious concept of CNS clearance	84
TGFβ signaling mediates microglial resilience to spatiotemporally restricted myelin degeneration	84
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	84
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	83
Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells	83
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	83
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	83
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	82
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	82
Using temperature to analyze the neural basis of a time-based decision	82
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	81
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	81
Thalamus-driven functional populations in frontal cortex support decision-making	81
Charting brain morphology in international healthy and neurological populations	81
How collaboration between bioethicists and neuroscientists can advance research	79
Semantic reconstruction of continuous language from non-invasive brain recordings	79
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	79
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	78
Complex topology meets simple statistics	77
(Lost) gut feeling	77
Gonads drive the brain	76
Refining the negative into general and specific	75
In conversation with Fernando de Castro Soubriet	75
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	74
Rapid motor skill adjustment is associated with population-level modulation of cerebellar error signals	73
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	73
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	73
Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation	72
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	72
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	72
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	71
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	71
TDP-43 loss brings RNA to a twist ending	71
Neurogenic–angiogenic synchrony via lactate	71
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	71
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	70

Estrogen dominance drives distinct patterns of brain plasticity	70
Freezing forgetting in C. elegans to extend memory retention	70
The cell-type underpinnings of the human functional cortical connectome	70
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	70
Sleep cycles process memories	70
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	70
A. D. (Bud) Craig, Jr. (1951–2023)	69
Restoring sensation to prosthetics	68
Mapping deep brain stimulation-modulated circuits via precision neuroimaging	68
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	68
Spatially clustered neurons in the bat midbrain encode vocalization categories	68
Liver-derived exercise factor boosts brain vasculature	68
Large-scale high-density brain-wide neural recording in nonhuman primates	67
Base barrier cells provide compartmentalization of choroid plexus, brain and CSF	67
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	67
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	66
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	66
Salience in the raphe	65
Anorexia nervosa microbiota	65
A very sexy circuit	65
A common voice for neural data	64
The eyes have it	63
Endocannabinoid protection of the brain vasculature leads to stress resilience	63
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	63
AI beats neuroscientists’ predictions	62
When protein turns toxic	61
Resilient cortical maps	61
Stress and autophagy	60
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	60
Author Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain	60
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	60
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	60
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	60
Control and recalibration of path integration in place cells using optic flow	60
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	59
Convergent information flows explain recurring firing patterns in cerebral cortex	59
Propagation of neuronal micronuclei regulates microglial characteristics	59
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	58
Persistent interferon signaling causes sensory neuron plasticity and pain before and during arthritis	58
Cerebellar associative learning underlies skilled reach adaptation	57
Updating the striatal–pallidal wiring diagram	57
Corticothalamic communication for action coordination in a skilled motor behavior	57
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	56
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	56
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	56
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	55
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	55
Blood-to-brain communication in aging and rejuvenation	55
The role of the lateral orbitofrontal cortex in creating cognitive maps	55
Gradients of neurotransmitter receptor expression in the macaque cortex	55
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	55
High-precision mapping reveals the structure of odor coding in the human brain	55
Blood proteins control microglia	54
Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning	54
In conversation with Aniruddha Das	54
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	53
Lewy body disease can spread via two distinct body-first routes	53
Place fields illuminated	53
Tirzepatide affects NAc activity and food preoccupation	53
Altruism and social rewards	53
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	52
Reducing publication bias with Registered Reports	52
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	52
Leveraging insights from neuroscience to build adaptive artificial intelligence	52
A unifying theory explains seemingly contradictory biases in perceptual estimation	52
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	52
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	51
Multilevel visual motion opponency in Drosophila	51
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	51
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	51
Value dynamics affect choice preparation during decision-making	51
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	51
Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS	51
A distinct hypothalamus–habenula circuit governs risk preference	51
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	50
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning	50
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	50
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	50
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	50
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	50
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	50
The prefrontal cortex controls memory organization in the hippocampus	50
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	49
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	49
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes	49
Twenty-five years of Nature Neuroscience	48
Lack of myelin improves axon survival in inflammatory lesions in the CNS	48
A cholinergic auditory pathway	48
Together but opposites in reward	48
Adolescent sleep molds adult social preferences	48
Parallel gut-to-brain pathways orchestrate feeding behaviors	47
The stop and go of glymphatic flow	47
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	47
Functionally diverse human insular architecture with memory-related hippocampal interactions	47
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine	47