Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	577
Salty licorice taste receptor	527
Non-REM sleep substates separate old and new memories	451
Alcohol’s necessary accessory	436
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	352
Daily feeding entrains hunger-sensing neurons	343
Neural basis of anticipation and premature impulsive action in the frontal cortex	315
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics	271
Neural basis of concurrent deliberation toward a choice and confidence judgment	269
Differential replay of reward and punishment paths predicts approach and avoidance	267
Computational complexity drives sustained deliberation	245
A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease	243
A hippocampal ‘sharp-wave sleep’ state that is dissociable from cortical sleep	238
Neurons in the caudal ventrolateral medulla mediate descending pain control	229
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	228
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy	227
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	225
Implementation and validation of single-cell genomics experiments in neuroscience	214
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	208
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	208
Climbing fibers provide essential instructive signals for associative learning	204
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	203
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	195
Pervasive environmental chemicals impair oligodendrocyte development	192
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	192

The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development	192
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	190
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	184
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	179
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	179
Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape	175
Genetic variants associated with longitudinal changes in brain structure across the lifespan	165
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	160
Intracellular chloride regulation mediates local sleep pressure in the cortex	159
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	158
Guest star in OCD	153
Organizing principles of the prefrontal cortex from a single-neuron projectome	151
Computational strategies for deliberative thought	151
How cancer and cortex collude	149
COVID-19 and brain aging	149
Lessons from resilience	146
Retraction Note: From neurons to microglia, with complements	144
Negative self-experiences shape responses to others’ emotional states	142
Glioblastoma–neuron networks	142
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	139
An organoid biobank for neurodevelopmental disorders	138
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	132
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	131
Gender and geographical disparity in editorial boards of journals in psychology and neuroscience	129
TDP-43 loss induces cryptic polyadenylation in ALS/FTD	129
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes	128
Common and stimulus-type-specific brain representations of negative affect	127
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	127
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	126
Psychedelic research must be grounded in pharmacology	120
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	117
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	117
Aging and injury drive neuronal senescence in the dorsal root ganglia	117
Marc G. Caron (1946–2022)	116
Aversion crosses over	115
Widespread brain–body integration during changes of arousal	113
A European perspective on structural barriers to women’s career progression in neuroscience	113
Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD	109
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing	109
Astrocytes make room for microglia	109
A neural mechanism for conserved value computations integrating information and rewards	109
Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy	109
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	107
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	107
CRISPRi screening in cultured human astrocytes uncovers distal enhancers controlling genes dysregulated in Alzheimer’s disease	106
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	105
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	104
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease	104
Adult-born dentate granule cells promote hippocampal population sparsity	102
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	102

Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	102
In conversation with Corey Harwell	101
The developmental emergence of reliable cortical representations	101
Activity map of a cortico-cerebellar loop underlying motor planning	101
A synergistic core for human brain evolution and cognition	101
Cerebellar organoids get active	100
Real control in virtual rats	100
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	100
Translation for transmission	100
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	100
Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery	99
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	97
Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms	97
Big data for classifying ASD	96
Chronic brain recordings reveal objective biomarkers of chronic pain	96
Facial expressions in mice reveal latent cognitive variables and their neural correlates	95
Commensals boost nerve regeneration	95
A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging	92
Flipping APOE to reverse Alzheimer’s disease traits	91
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	90
Increased neural excitability and glioma synaptic activity drives glioma proliferation in human cortex	88
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging	88
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	88
Dynamics of mature myelin	88
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	87
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	87
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	87
Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	87
How to build a cognitive map	86
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state	86
A fragile imbalance	85
In conversation with Carla Shatz	84
Personalized EES for SCI	84
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	83
AI predicts risk of mental health disorders	83
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	83
Gene programs driving cortical neuron specifications	82
Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells	82
From pain to brain	81
How the brain regulates its own immune system	81
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	81
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	80
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	80
Reply to: A curious concept of CNS clearance	79
Publisher Correction: Hormonal milieu influences whole-brain structural dynamics across the menstrual cycle using dense sampling in multiple individuals	79
How collaboration between bioethicists and neuroscientists can advance research	79
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways	79
Using temperature to analyze the neural basis of a time-based decision	78
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	78
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	77
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	77
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement	77
Charting brain morphology in international healthy and neurological populations	76
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	76
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	76
Shared computational principles for language processing in humans and deep language models	75
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	75
Semantic reconstruction of continuous language from non-invasive brain recordings	75
Natural language instructions induce compositional generalization in networks of neurons	75
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	75
Thalamus-driven functional populations in frontal cortex support decision-making	75
Complex topology meets simple statistics	74
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	74
(Lost) gut feeling	74
In conversation with Fernando de Castro Soubriet	73
Gonads drive the brain	73
Refining the negative into general and specific	72
TDP-43 loss brings RNA to a twist ending	71
Silencing gut CCK cells alters gut reaction to sugar	71
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	71
Spatially clustered neurons in the bat midbrain encode vocalization categories	71
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	70
Sleep cycles process memories	70
Neurogenic–angiogenic synchrony via lactate	70
A. D. (Bud) Craig, Jr. (1951–2023)	69
Estrogen dominance drives distinct patterns of brain plasticity	69
Rapid motor skill adjustment is associated with population-level modulation of cerebellar error signals	69
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	68
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	68
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	68

Freezing forgetting in C. elegans to extend memory retention	67
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	67
Restoring sensation to prosthetics	67
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	66
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	66
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	66
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	65
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	65
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains	65
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	65
Thalamic subnetworks as units of function	65
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus	65
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)	64
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	64
The cell-type underpinnings of the human functional cortical connectome	64
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	64
Large-scale high-density brain-wide neural recording in nonhuman primates	63
Anorexia nervosa microbiota	62
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	62
A very sexy circuit	62
Salience in the raphe	62
The eyes have it	61
A common voice for neural data	61
Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans	60
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	60
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	60
Resilient cortical maps	59
Endocannabinoid protection of the brain vasculature leads to stress resilience	59
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	59
AI beats neuroscientists’ predictions	59
Stress and autophagy	59
When protein turns toxic	58
Author Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain	58
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	58
Propagation of neuronal micronuclei regulates microglial characteristics	57
Cerebellar associative learning underlies skilled reach adaptation	57
Convergent information flows explain recurring firing patterns in cerebral cortex	57
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	57
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	56
Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning	56
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	55
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	55
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	55
Control and recalibration of path integration in place cells using optic flow	55
The role of the lateral orbitofrontal cortex in creating cognitive maps	54
Blood-to-brain communication in aging and rejuvenation	54
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	54
High-precision mapping reveals the structure of odor coding in the human brain	54
Updating the striatal–pallidal wiring diagram	54
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	53
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	53
Gradients of neurotransmitter receptor expression in the macaque cortex	53
In conversation with Aniruddha Das	52
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	52
Blood proteins control microglia	52
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	52
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	52
Altruism and social rewards	51
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	51
Lewy body disease can spread via two distinct body-first routes	51
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	51
Puberty reverses sex differences in learning	51
Place fields illuminated	51
Multilevel visual motion opponency in Drosophila	50
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	50
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning	49
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	49
Value dynamics affect choice preparation during decision-making	49
Tirzepatide affects NAc activity and food preoccupation	48
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	48
Reducing publication bias with Registered Reports	48
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes	47
A unifying theory explains seemingly contradictory biases in perceptual estimation	47
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	47
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	47
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	47
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	46
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	46
A distinct hypothalamus–habenula circuit governs risk preference	46
Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS	46
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	45
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	45
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	45
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	45
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	45
Leveraging insights from neuroscience to build adaptive artificial intelligence	45
Adolescent sleep molds adult social preferences	44
Twenty-five years of Nature Neuroscience	44
Lack of myelin improves axon survival in inflammatory lesions in the CNS	44
A cholinergic auditory pathway	44
Multi-region m6A epitranscriptome profiling of the human brain reveals spatial and temporal variation and enrichment of disease-associated loci	43
Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia	43
Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits	43
A motor association area in the depths of the central sulcus	43
Together but opposites in reward	43