International Journal of Molecular Medicine

Papers
(The TQCC of International Journal of Molecular Medicine is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Pyroptosis in gastric mucosal injury‑related diseases (Review)401
Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states88
[Retracted] TGF‑β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis83
[Retracted] Long noncoding RNA SNHG14 promotes the aggressiveness of retinoblastoma by sponging microRNA‑124 and thereby upregulating STAT372
YWHAH‑driven autophagy via MAPK/ERK signaling enhances CRC cell migration and invasion67
Inhibitory effect of PDE2 on inflammation and apoptosis in cerebral ischemia‑reperfusion injury59
Common methods in mitochondrial research (Review)59
Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)58
Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)55
Laminin α1 as a target for the treatment of epidural fibrosis by regulating fibrotic mechanisms50
TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation49
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration49
[Retracted] Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure46
Epstein‑Barr virus as a promoter of tumorigenesis in the tumor microenvironment of breast cancer (Review)44
Effects of sesamin on the chemosensitivity, invasiveness and immune evasion mechanism of human lung adenocarcinoma44
Research progress, challenges and perspectives of phospholipids metabolism in the LXR‑LPCAT3 signaling pathway and its relation to NAFLD (Review)44
New advances of nanozymes for the diagnosis and treatment of digestive system diseases (Review)43
miR‑4730 suppresses the progression of liver cancer by targeting the high mobility group A1 pathway42
Targeting p38 MAPK signaling pathway:  Quercetin as a novel therapy for TMJ synovitis41
NLRP3 inflammasome in health and disease (Review)40
[Retracted] Downregulation of CKS1B restrains the proliferation, migration, invasion and angiogenesis of retinoblastoma cells through the MEK/ERK signaling pathway39
Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease (Review)39
Hydrogen sulfide attenuates cigarette smoke‑induced pyroptosis through the TLR4/NF‑κB signaling pathway38
Enocyanin promotes osteogenesis and bone regeneration by inhibiting MMP937
Exosomes derived from human dermal fibroblasts protect against UVB‑induced skin photoaging37
Current strategies for nonalcoholic fatty liver disease treatment (Review)36
[Retracted] Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway36
Effects and potential mechanism of Ca2+/calmodulin‑dependent protein kinase II pathway inhibitor KN93 on the development of ovarian follicle35
Takotsubo syndrome: Unraveling the mystery behind its triggers (Review)35
Role and mechanisms of noncoding RNAs in the regulation of metabolic reprogramming in bladder cancer (Review)35
Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF34
Human umbilical cord mesenchymal stem cell‑derived exosomes improve ovarian function in natural aging by inhibiting apoptosis33
Association of endometriosis with cardiovascular disease: Genetic aspects (Review)33
Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway32
Mitochondrial dysfunction in chronic neuroinflammatory diseases (Review)31
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.231
Identification of novel molecules and pathways associated with fascin actin‑bundling protein 1 in laryngeal squamous cell carcinoma through comprehensive transcriptome analysis30
[Corrigendum] Μolecular impact of bone morphogenetic protein 7, on lung cancer cells and its clinical significance30
MEIS1‑regulated miR‑488‑3p suppresses the malignant progression of laryngeal squamous cell carcinoma by targeting ACVR1C30
Mechanisms of action of retinal microglia in diabetic retinopathy (Review)29
Cholesterol metabolism and cancer: Molecular mechanisms, immune regulation and an epidemiological perspective (Review)29
Apelin‑13 in the paraventricular nucleus (PVN) attenuates myocardial ischemia through V1a receptors in PVN/nucleus tractus solitarii (NTS) and GARγ2 in NTS28
HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple‑negative breast cancer metastasis via the inhibition of CXCR4 expression27
Effects of Sulforaphane on SARS‑CoV‑2 infection and NF‑κB dependent expression of genes involved in the COVID‑19 ‘cytokine storm’26
[Retracted] Sirt1 inhibits HG‑induced endothelial injury: Role of Mff‑based mitochondrial fission and F‑actin homeostasis‑mediated cellular migration26
Understanding the impact of mitochondrial DNA mutations on aging and carcinogenesis (Review)25
Attenuation of hepatic ischemia‑reperfusion injury by adipose stem cell‑derived exosome treatment via ERK1/2 and GSK‑3β signaling pathways25
Upregulation of MTHFD2 is associated with PD‑L1 activation in bladder cancer via the PI3K/AKT pathway24
Free fatty acids induce coronary microvascular dysfunction via inhibition of the AMPK/KLF2/eNOS signaling pathway24
Protective effect of exercise on metabolic dysfunction‑associated fatty liver disease: Potential epigenetic mechanisms (Review)23
Predictive value of the sFlt‑1/PlGF ratio in women with suspected preeclampsia: An update (Review)23
Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy23
Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease23
[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues23
From banked human cord blood to induced pluripotent stem cells: New opportunities and promise in induced pluripotent stem cell banking (Review)23
Current status of severe fever with thrombocytopenia syndrome in China (Review)22
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ322
Multifaceted regulation and functions of 53BP1 in NHEJ‑mediated DSB repair (Review)21
Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy via the miR‑18a‑3p/Gsdmd pathway21
[Corrigendum] Pharmacokinetics and antitumor efficacy of DSPE‑PEG2000 polymeric liposomes loaded with quercetin and temozolomide: Analysis of their effectiveness in enhancing the chemosensitization of20
[Corrigendum] A potential therapeutic effect of CYP2C8 overexpression on anti‑TNF‑α activity20
[Retracted] Isopsoralen‑mediated suppression of bone marrow adiposity and attenuation of the adipogenic commitment of bone marrow‑derived mesenchymal stem cells19
Vitamin D affects antiphospholipid syndrome by regulating T cells (Review)19
[Retracted] Knockdown of SNHG16 suppresses the proliferation and induces the apoptosis of leukemia cells via miR‑193a‑5p/CDK819
[Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway19
m6A modification of non‑coding RNA: Mechanisms, functions and potential values in human diseases (Review)18
MTHFD2 promotes esophageal squamous cell carcinoma progression via m6A modification‑mediated upregulation and modulation of the PEBP1‑RAF1 interaction18
HIF‑1α: Its notable role in the maintenance of oxygen, bone and iron homeostasis (Review)18
Doxorubicin sensitizes breast cancer cells to natural killer cells in connection with increased Fas receptors18
Lymphangiogenesis: A new strategy for heart disease treatment (Review)18
Elimination of intracellular Ca2+ overload by BAPTA‑AM liposome nanoparticles: A promising treatment for acute pancreatitis18
[Expression of Concern] S100A8‑targeting siRNA enhances arsenic trioxide‑induced myeloid leukemia cell death by down‑regulating autophagy18
Exploring the association between melatonin and nicotine dependence (Review)17
Short‑chain fatty acids regulate hepatocellular carcinoma progression: A metabolic perspective on tumor immunity (Review)17
Deciphering the emerging landscape of HOX genes in cardiovascular biology, atherosclerosis and beyond (Review)17
Molecular pathways associated with oxidative stress and their potential applications in radiotherapy (Review)16
Study on the in vitro changes of human bone marrow‑related mesenchymal stem cells16
C3a/C3aR axis is involved in diabetic kidney injury by regulating podocyte mitophagy in diabetic nephropathy16
Quercetin ameliorates senescence and promotes osteogenesis of BMSCs by suppressing the repetitive element‑triggered RNA sensing pathway16
[Corrigendum] miR‑490‑5p regulates the proliferation, migration, invasion and epithelial‑mesenchymal transition of pharyngolaryngeal cancer cells by targeting mitogen‑activated protein kinase kinase k16
GW8510 alleviates muscle atrophy and skeletal muscle dysfunction in mice through AMPK/PGC1α signaling16
Emerging role of small RNAs in inflammatory bowel disease and associated colorectal cancer (Review)16
Importance of STAT3 signaling in preeclampsia (Review)16
[Corrigendum] Knockdown of HOXA10 reverses the multidrug resistance of human chronic mylogenous leukemia K562/ADM cells by downregulating P‑gp and MRP‑116
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy16
The gut‑skin axis: Emerging insights in understanding and treating skin diseases through gut microbiome modulation (Review)16
New insights into the role of ubiquitination in angiogenesis (Review)15
In situ hybridization for the assessment of urokinase plasminogen activator and plasminogen activator inhibitor type‑1 in formalin‑fixed paraffin‑embedded breast cancer specimens15
Ferroptosis and head and neck cancer: Mechanisms and therapeutic perspectives (Review)15
MicroRNA‑885‑5p regulates cell cycle progression in liver cancer cells15
Inflammation and coagulation abnormalities via the activation of the HMGB1‑RAGE/NF‑κB and F2/Rho pathways in lung injury induced by acute hypoxia15
ZNF667 facilitates angiogenesis after myocardial ischemia through transcriptional regulation of VASH1 and Wnt signaling pathway15
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines15
[Retracted] Hedgehog signaling is involved in the BMP9‑induced osteogenic differentiation of mesenchymal stem cells15
Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review)15
[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes15
Dysregulated programmed cell death of intestinal epithelial cells in ulcerative colitis: Molecular mechanisms and novel therapeutic interventions (Review)14
Metformin prevents the onset and progression of intervertebral disc degeneration: New insights and potential mechanisms (Review)14
Current updates regarding biogenesis, functions and dysregulation of microRNAs in cancer: Innovative approaches for detection using CRISPR/Cas13‑based platforms (Review)14
Beclin‑1 exerts protective effects against cerebral ischemia‑reperfusion injury by promoting DNA damage repair through a non‑autophagy‑dependent regulatory mechanism14
Osteoking exerts pro‑osteogenic and anti‑adipogenic effects in promoting bone fracture healing via EGF/EGFR/HDAC1/Wnt/β‑catenin signaling14
Unveiling the multifaceted role of adropin in various diseases (Review)14
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer13
Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome13
Gossypin induces apoptosis and autophagy via the MAPK/JNK pathway in HT‑29 human colorectal cancer cells12
PANoptosis: Novel insight into regulated cell death and its potential role in cardiovascular diseases (Review)12
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways12
New insight for SS‑31 in treating diabetic cardiomyopathy: Activation of mitoGPX4 and alleviation of mitochondria‑dependent ferroptosis12
Role of lysine lactylation in neoplastic and inflammatory pulmonary diseases (Review)12
Molecular mechanisms and clinicopathological characteristics of inhibin βA in thyroid cancer metastasis12
Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice12
lncRNA DHFRL1‑4 knockdown attenuates cerebral ischemia/reperfusion injury by upregulating the levels of angiogenesis‑related genes12
Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer12
Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)12
Circular RNAs and the regulation of gene expression in diabetic nephropathy (Review)12
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy12
Copper supplementation alleviates hypoxia‑induced ferroptosis and oxidative stress in neuronal cells12
Ablation of CXCR4 expression in cardiomyocytes exacerbates isoproterenol‑induced cell death and heart failure12
Insight into microbial extracellular vesicles as key communication materials and their clinical implications for lung cancer (Review)12
Repositioning of aripiprazole, an anti‑psychotic drug, to sensitize the chemotherapy of pancreatic cancer12
Spotlight on HOX cluster‑embedded antisense lncRNAs in cardiovascular diseases (Review)12
SDF2 promotes glioma progression via GRP78‑mediated ERAD and copper homeostasis disruption11
Changes in the endoplasmic reticulum‑mitochondria communication in dermal fibroblasts from early‑stage bipolar disorder patients: Skin‑brain axis as a new route to understand the pathophysiology of me11
[Retracted] miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab1011
[Retracted] Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway11
Lipid metabolism in microglia: Emerging mechanisms and therapeutic opportunities for neurodegenerative diseases (Review)11
[Retracted] Altered expression of miR‑92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis11
Multidisciplinary approaches to study anaemia with special mention on aplastic anaemia (Review)11
Silencing of circular RNA‑ZYG11B exerts a neuroprotective effect against retinal neurodegeneration11
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD411
[Corrigendum] Bax inhibitor‑1 suppresses early brain injury following experimental subarachnoid hemorrhage in rats11
[Corrigendum] SCF increases cardiac stem cell migration through PI3K/AKT and MMP‑2/‑9 signaling11
[Retracted] Antagonist targeting miR‑106b‑5p attenuates acute renal injury by regulating renal function, apoptosis and autophagy via the upregulation of TCF411
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway11
miR‑27b‑3p modulates CD4+CD39+ Tregs to drive immune‑mediated intervertebraldisc degeneration11
Stanniocalcin‑1 suppresses TGF‑β‑induced mitochondrial dysfunction and cellular fibrosis in human renal proximal tubular cells11
Mitochondrial dysfunction in perimenopausal mood disorders: From hormonal shifts to neuroenergetic failure (Review)11
[Corrigendum] miR‑29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC‑1α signaling: Implications for age‑related hearing loss11
13‑cis‑retinoic acid inhibits the self‑renewal, migration, invasion and adhesion of cholangiocarcinoma cells10
Metformin reverses oxidative stress‑induced mitochondrial dysfunction in pre‑osteoblasts via the EGFR/GSK‑3β/calcium pathway10
Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)10
Multi‑omics analysis of right ventricles in rat models of pulmonary arterial hypertension: Consideration of mitochondrial biogenesis by chrysin10
Giant Centella asiatica, a novel cultivar rich in madecassoside and asiaticoside, suppresses α‑melanocyte‑stimulating hormone‑induced melanogenesis through MC1R binding10
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis10
Advances in the study of regulators of ferroptosis in head and neck squamous cell carcinoma (Review)10
[Corrigendum] Spicatoside A in red Liriope platyphylla displays a laxative effect in a constipation rat model via regulating mAChRs and ER stress signaling10
Insights on the differences between two‑ and three‑dimensional culture systems in tumor models (Review)10
Role of the TGF‑β/Smad signaling pathway in the transition from acute kidney injury to chronic kidney disease (Review)10
Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)10
Topical calcineurin and mammalian target of rapamycin inhibitors in inflammatory dermatoses: Current challenges and nanotechnology‑based prospects (Review)9
Role of solute carrier transporters in ovarian cancer (Review)9
Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)9
Activin A rescues preterm brain injury through a novel Noggin/BMP4/Id2 signaling pathway9
Paeoniflorigenone inhibits ovarian cancer metastasis through targeting the MUC1/Wnt/β‑catenin pathway9
Research progress in myocardial function and diseases related to muscarinic acetylcholine receptor (Review)9
Dual roles of oxostephanine as an Aurora kinase inhibitor and angiogenesis suppressor9
Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)9
2,3,4',5‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside ameliorates gentamicin‑induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling9
Role of MEX3A in tumorigenesis: Mechanisms, tumor‑specific effects and therapeutic implications (Review)9
Splice variants denote differences between a cancer stem cell side population of EWSR1‑ERG‑based Ewing sarcoma cells, its main population and EWSR1‑FLI‑based cells9
Effects of DNA methylation and its application in inflammatory bowel disease (Review)9
Lamin B2 contributes to the proliferation of bladder cancer cells via activating the expression of cell division cycle‑associated protein 39
Research progress on mesenchymal stem cell‑derived exosomes in the treatment of osteoporosis induced by knee osteoarthritis (Review)9
[Corrigendum] Morroniside protects SK‑N‑SH human neuroblastoma cells against H2O2‑induced damage9
Thrombocytopenia in COVID‑19 and vaccine‑induced thrombotic thrombocytopenia9
Tanshinone IIA protects against chronic obstructive pulmonary disease via exosome‑shuttled miR‑486‑5p9
Compound Kushen injection attenuates angiotensin II‑mediated heart failure by inhibiting the PI3K/Akt pathway9
Expansion of B10 cells in vitro: Pathways, techniques and applications in transplantation (Review)9
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