International Journal of Molecular Medicine

Article	Citations
IL13Rα2‑ and EGFR‑targeted pseudomonas exotoxin potentiates the TRAIL‑mediated death of GBM cells	255
[Retracted] Sulforaphane regulates apoptosis‑ and proliferation‑related signaling pathways and synergizes with cisplatin to suppress human ovarian cancer	155
HINT3 suppresses AKT/mTOR signaling pathway activity during breast cancer tumorigenesis through PTEN transcriptional activation	121
[Corrigendum] The role of VIT1/FBXO11 in the regulation of apoptosis and tyrosinase export from endoplasmic reticulum in cultured melanocytes	117
[Retracted] Adipose extracellular matrix promotes skin wound healing by inducing the differentiation of adipose‑derived stem cells into fibroblasts	102
[Retracted] Downregulation of CKS1B restrains the proliferation, migration, invasion and angiogenesis of retinoblastoma cells through the MEK/ERK signaling pathway	96
KIF4A promotes the development of bladder cancer by transcriptionally activating the expression of CDCA3	58
[Retracted] TGF‑β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis	58
[Retracted] Astragaloside IV inhibits oxidized low‑density lipoprotein‑induced endothelial damage via upregulation of miR‑140‑3p	54
[Corrigendum] Nano‑hydroxyapatite/collagen film as a favorable substrate to maintain the phenotype and promote the growth of chondrocytes cultured in vitro	51
lncRNA DHFRL1‑4 knockdown attenuates cerebral ischemia/reperfusion injury by upregulating the levels of angiogenesis‑related genes	51
Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma	48
Triptonide protects retinal cells from oxidative damage via activation of Nrf2 signaling	47
Calcium chelator BAPTA‑AM protects against iron overload‑induced chondrocyte mitochondrial dysfunction and cartilage degeneration	46
[Corrigendum] MicroRNA‑24 attenuates diabetic vascular remodeling by suppressing the NLRP3/caspase‑1/IL‑1β signaling pathway	45
[Corrigendum] Dendritic cell‑derived exosomal miR‑494‑3p promotes angiogenesis following myocardial infarction	44
An LGR4 agonist activates the GSK‑3β pathway to inhibit RANK‑RANKL signaling during osteoclastogenesis in bone marrow‑derived macrophages	41
[Retracted] Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin‑1 in breast cancer cells	38
[Retracted] Circular RNA CSNK1G1 promotes the progression of osteoarthritis by targeting the miR‑4428/FUT2 axis	37
[Retracted] Suppression of endoplasmic reticulum stress‑induced invasion and migration of breast cancer cells through the downregulation of heparanase	37
[Retracted] MicroRNA‑718 serves a tumor‑suppressive role in non‑small cell lung cancer by directly targeting CCNB1	36
Intracellular CIRP promotes liver regeneration via STAT3 signaling pathway activation after partial hepatectomy in mice	35
[Retracted] Long noncoding RNA SNHG14 promotes the aggressiveness of retinoblastoma by sponging microRNA‑124 and thereby upregulating STAT3	35
Research progress on the molecular mechanisms of Saikosaponin D in various diseases (Review)	35
NLRP3 inflammasome in health and disease (Review)	34

Potential and challenges of utilizing exosomes in osteoarthritis therapy (Review)	34
Ablation of CXCR4 expression in cardiomyocytes exacerbates isoproterenol‑induced cell death and heart failure	33
Clarifying the molecular mechanism of tomentosin‑induced antiproliferative and proapoptotic effects in human multiple myeloma via gene expression profile and genetic interaction network analysis	33
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition	32
[Corrigendum] Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury in rats	31
[Retracted] KIF22 promotes bladder cancer progression by activating the expression of CDCA3	30
Exosomes derived from human dermal fibroblasts protect against UVB‑induced skin photoaging	29
Claudin 1, 4, 6 and 18 isoform 2 as targets for the treatment of cancer (Review)	29
[Corrigendum] Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes	29
Role of Agrin in tissue repair and regeneration: From mechanisms to therapeutic opportunities (Review)	29
A functional polymorphism at the miR‑491‑5p binding site in the 3'‑untranslated region of the MMP‑9 gene increases the risk of developing ventilator‑associated pneumonia	28
Molecular mechanisms and clinicopathological characteristics of inhibin βA in thyroid cancer metastasis	28
Inhibitory effect of PDE2 on inflammation and apoptosis in cerebral ischemia‑reperfusion injury	28
Enhancing diabetic foot ulcer healing: Impact of the regulation of the FUS and ILF2 RNA‑binding proteins through negative pressure wound therapy	28
RKIP suppresses the influenza A virus‑induced airway inflammatory response via the ERK/MAPK pathway	27
Protein aggregation and biomolecular condensation in hypoxic environments (Review)	26
Laminin α1 as a target for the treatment of epidural fibrosis by regulating fibrotic mechanisms	26
Arctiin attenuates iron overload‑induced osteoporosis by regulating the PI3K/Akt pathway	25
Hydrogen sulfide attenuates cigarette smoke‑induced pyroptosis through the TLR4/NF‑κB signaling pathway	25
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration	24
TMEM16 proteins: Ca2+‑activated chloride channels and phospholipid scramblases as potential drug targets (Review)	24
Pro‑differentiating compounds for human intervertebral disc cells are present in Violina pumpkin leaf extracts	24
TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation	24
Metabolic heterogeneity protects metastatic mucosal melanomas cells from ferroptosis	23
Myocardin‑related transcription factor A nuclear translocation contributes to mechanical overload‑induced nucleus pulposus fibrosis in rats with intervertebral disc degeneration	23
Apelin‑13 alleviates diabetic nephropathy by enhancing nitric oxide production and suppressing kidney tissue fibrosis	23
Pericyte‑derived extracellular vesicles‑mimetic nanovesicles improves peripheral nerve regeneration in mouse models of sciatic nerve transection	22
Effect and mechanism of propranolol on promoting osteogenic differentiation and early implant osseointegration	22
Role of integrin‑linked kinase in static compressive stress‑induced autophagy via phosphatidylinositol 3 kinase in human periodontal ligament cells	22
Role of the m6A demethylase ALKBH5 in gastrointestinal tract cancer (Review)	21
Role and mechanism of chaperones calreticulin and ERP57 in restoring trafficking to mutant HERG‑A561V protein	21
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy	21
[Corrigendum] Abnormal expression of SIRTs in psoriasis: Decreased expression of SIRT 1‑5 and increased expression of SIRT 6 and 7	21
miR‑4730 suppresses the progression of liver cancer by targeting the high mobility group A1 pathway	20
RepSox effectively promotes the induced differentiation of sheep fibroblasts into adipocytes via the inhibition of the TGF‑β1/Smad pathway	20
ABCG8‑mediated sterol efflux increases cancer cell progression via the LRP6/Wnt/β‑catenin signaling pathway in radiotherapy‑resistant MDA‑MB‑231 triple‑negative breast cancer cells	20
Impact of CYLD on chromatin structure and histone methylation in malignant melanoma	20
Role of the S100 protein family in liver disease (Review)	20
Downregulating FGGY carbohydrate kinase domain containing promotes cell senescence by activating the p53/p21 signaling pathway in colorectal cancer	20
Role of Ca2+ channels in non-alcoholic fatty liver disease and their implications for therapeutic strategies (Review)	20
Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states	20
[Corrigendum] A regulation loop between Nrf1α and MRTF‑A controls migration and invasion in MDA‑MB‑231 breast cancer cells	20
Taxifolin suppresses the malignant progression of gastric cancer by regulating the AhR/CYP1A1 signaling pathway	19
Development of a cancer cells self‑activating and miR‑125a‑5p expressing poly‑pharmacological nanodrug for cancer treatment	19
Pathophysiology of stress granules: An emerging link to diseases (Review)	19
New insight for SS‑31 in treating diabetic cardiomyopathy: Activation of mitoGPX4 and alleviation of mitochondria‑dependent ferroptosis	19
Inhibition of HDAC6 alleviates cancer‑induced bone pain by reducing the activation of NLRP3 inflammasome	19
The metabolic and molecular mechanisms of α‑mangostin in cardiometabolic disorders (Review)	19
Autologous cell therapy in diabetes‑associated critical limb ischemia: From basic studies to clinical outcomes (Review)	19
Overexpression of salusin‑α upregulates AdipoR2 and activates the PPARα/ApoA5/SREBP‑1c pathway to inhibit lipid synthesis in HepG2 cells	18

Role of 2‑series prostaglandins in the pathogenesis of type 2 diabetes mellitus and non‑alcoholic fatty liver disease (Review)	18
[Corrigendum] Effects of miR‑340 overexpression and knockdown on the proliferation and metastasis of NSCLC cell lines	18
Mechanisms of microRNA‑142 in mitochondrial autophagy and hippocampal damage in a rat model of epilepsy	18
Common methods in mitochondrial research (Review)	18
TP53 mutations in cancer: Molecular features and therapeutic opportunities (Review)	17
Remimazolam alleviates myocardial ischemia/reperfusion injury and inflammation via inhibition of the NLRP3/IL‑1β pathway in mice	17
Comparison of HepaRG and HepG2 cell lines to model mitochondrial respiratory adaptations in non‑alcoholic fatty liver disease	17
Repositioning of aripiprazole, an anti‑psychotic drug, to sensitize the chemotherapy of pancreatic cancer	17
miR‑100: A key tumor suppressor regulatory factor in human malignant tumors (Review)	17
Spotlight on HOX cluster‑embedded antisense lncRNAs in cardiovascular diseases (Review)	17
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation	17
Elevated neuregulin‑1 expression modulates tumor malignancy and autophagy in esophageal squamous cell carcinoma	17
Ultrasound‑targeted microbubble destruction technology delivering β‑klotho to the heart enhances FGF21 sensitivity and attenuates heart remodeling post‑myocardial infarction	16
Role of lysine lactylation in neoplastic and inflammatory pulmonary diseases (Review)	15
Role of ubiquitination in the occurrence and development of osteoporosis (Review)	15
Epstein‑Barr virus as a promoter of tumorigenesis in the tumor microenvironment of breast cancer (Review)	15
Protective effect of ginseng extract and total ginsenosides on hematopoietic stem cell damage by inhibiting cell apoptosis and regulating the intestinal microflora	15
Euphorbia factor L2 suppresses the generation of liver metastatic ascites in breast cancer via inhibiting NLRP3 inflammasome activation	15
Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease (Review)	15
Protective role of wogonin following traumatic brain injury by reducing oxidative stress and apoptosis via the PI3K/Nrf2/HO‑1 pathway	14
Role of GLP‑1 receptor agonists in sepsis and their therapeutic potential in sepsis‑induced muscle atrophy (Review)	14
2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines	14
CircRNA: A novel potential strategy to treat thyroid cancer (Review)	14
Extracellular vesicles from tonsil‑derived mesenchymal stromal cells show anti‑tumor effect via miR‑199a‑3p	14
Neutrophil extracellular traps promote gastric cancer metastasis by inducing epithelial‑mesenchymal transition	14
Research progress, challenges and perspectives of phospholipids metabolism in the LXR‑LPCAT3 signaling pathway and its relation to NAFLD (Review)	14
Downregulation of HAS‑2 regulates the chondrocyte cytoskeleton and induces cartilage degeneration by activating the RhoA/ROCK signaling pathway	14
The impact of diet upon mitochondrial physiology (Review)	13
Piperlongumine induces apoptosis via the MAPK pathway and ERK‑mediated autophagy in human melanoma cells	13
Overview of the immunological mechanism underlying severe fever with thrombocytopenia syndrome (Review)	13
Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis	13
Role of microglia/macrophage polarisation in intraocular diseases (Review)	13
An update on genetic basis of generalized pustular psoriasis (Review)	13
MEIS1 and its potential as a cancer therapeutic target (Review)	13
Role of ferroptosis in the pathogenesis and as a therapeutic target of inflammatory bowel disease (Review)	13
Molecular and cellular mechanisms of spastin in neural development and disease (Review)	13
Neuronal injuries in cerebral infarction and ischemic stroke: From mechanisms to treatment (Review)	13
[Corrigendum] Use of methylation profiling to identify significant differentially methylated genes in bone marrow mesenchymal stromal cells from acute myeloid leukemia	12
[Corrigendum] MicroRNA‑218 inhibits the proliferation and metastasis of esophageal squamous cell carcinoma cells by targeting BMI1	12
Demetra Application: An integrated genotype analysis web server for clinical genomics in endometriosis	12
Long noncoding RNA network: Novel insight into hepatocellular carcinoma metastasis (Review)	12
Platelet activation stimulates macrophages to enhance ulcerative colitis through PF4/CXCR3 signaling	12
Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway	12
Overexpression of miR‑375 reverses the effects of dexamethasone on the viability, migration, invasion and apoptosis of human airway epithelial cells by targeting DUSP6	12
Salusin‑α alleviates lipid metabolism disorders via regulation of the downstream lipogenesis genes through the LKB1/AMPK pathway	12
Role and mechanisms of noncoding RNAs in the regulation of metabolic reprogramming in bladder cancer (Review)	12
Circular RNAs and the regulation of gene expression in diabetic nephropathy (Review)	12
Immune response (IgG) following full inoculation with BNT162b2 COVID‑19 mRNA among healthcare professionals	12
RAS‑stimulated release of exosomal miR‑494‑3p promotes the osteolytic bone metastasis of breast cancer cells	11
[Retracted] Antagonist targeting miR‑106b‑5p attenuates acute renal injury by regulating renal function, apoptosis and autophagy via the upregulation of TCF4	11
[Corrigendum] MCMV triggers ROS/NLRP3‑associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss	11
Overexpression of microRNA‑486 affects the proliferation and chemosensitivity of mesothelioma cell lines by targeting PIM1	11
[Corrigendum] Knockdown of mesenchymal stem cell‑derived exosomal LOC100129516 suppresses the symptoms of atherosclerosis via upregulation of the PPARγ/LXRα/ABCA1 signaling pathway	11
Genotoxicity of chloroacetamide herbicides and their metabolites in vitro and in vivo	11
[Corrigendum] miR‑29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC‑1α signaling: Implications for age‑related hearing loss	11
[Corrigendum] Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway	11
Association of endometriosis with cardiovascular disease: Genetic aspects (Review)	11
[Corrigendum] SCF increases cardiac stem cell migration through PI3K/AKT and MMP‑2/‑9 signaling	11
Silencing of circular RNA‑ZYG11B exerts a neuroprotective effect against retinal neurodegeneration	11
miR‑30a‑5p mitigates autophagy by regulating the Beclin‑1/ATG16 pathway in renal ischemia/reperfusion injury	11
Gab2 promotes the growth of colorectal cancer by regulating the M2 polarization of tumor‑associated macrophages	11
E74‑like ETS transcription factor 5 facilitates cell proliferation through regulating the expression of adenomatous polyposis coli 2 in non‑small cell lung cancer	10
Role of Sam68 in different types of cancer (Review)	10
Connexins and angiogenesis: Functional aspects, pathogenesis, and emerging therapies (Review)	10
Multidisciplinary approaches to study anaemia with special mention on aplastic anaemia (Review)	10
[Corrigendum] Synergistic cardioprotective effects of Danshensu and hydroxysafflor yellow A against myocardial ischemia-reperfusion injury are mediated through the Akt/Nrf2/HO-1 pathway	10
Enocyanin promotes osteogenesis and bone regeneration by inhibiting MMP9	10
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2	10
Interference with the expression of S1PR1 or STAT3 attenuates valvular damage due to rheumatic heart disease	10
Selective inhibition of JNK located on mitochondria protects against mitochondrial dysfunction and cell death caused by endoplasmic reticulum stress in mice with LPS‑induced ALI/ARDS	10
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway	10
[Retracted] Ubiquitin‑specific protease 4 inhibits breast cancer cell growth through the upregulation of PDCD4	10
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway	10
Effects of PCSK9 on thrombosis and haemostasis in a variety of metabolic states: Lipids and beyond (Review)	10
Role of microRNA‑375‑3p‑mediated regulation in tinnitus development	10
Roles of long non‑coding RNAs in esophageal cell squamous carcinoma (Review)	9
Effect of EGCG on bronchial epithelial cell premalignant lesions induced by cigarette smoke and on its CYP1A1 expression	9
Starvation mediates pancreatic cancer cell sensitivity to ferroptosis via ERK1/2, JNK and changes in the cell mesenchymal state	9
Scutellarein regulates the PTEN/AKT/NFκB signaling pathway to reduce pirarubicin related liver inflammation	9
miR‑29b suppresses proliferation and induces apoptosis of hepatocellular carcinoma ascites H22 cells via regulating TGF‑β1 and p53 signaling pathway	9

Smooth muscle cells, interstitial cells and neurons in the gallbladder (GB): Functional syncytium of electrical rhythmicity and GB motility (Review)	9
MicroRNA‑101 inhibits renal tubular epithelial‑to‑mesenchymal transition by targeting TGF‑β1 type I receptor	9
[Retracted] Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway	9
Antioxidant stress and anticancer activity of peptide‑chelated selenium in vitro	9
Pathology and physiology of acid‑sensitive ion channels in the digestive system (Review)	9
Molecular modelling of novel ADCY3 variant predicts a molecular target for tackling obesity	9
Comparative analysis of long non‑coding RNA expression profiles induced by resveratrol and metformin treatment for hepatic insulin resistance	9
Interleukin‑27 ameliorates allergic asthma by alleviating the lung Th2 inflammatory environment	9
Unveiling the role of RhoA and ferroptosis in vascular permeability: Implications for osteoarthritis	9
lncRNA NORAD is consistently detected in breastmilk exosomes and its expression is downregulated in mothers of preterm infants	9