OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Headache and Pain is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Identification of disease- and headache-specific mediators and pathways in migraine using blood transcriptomic and metabolomic analysis	458
Efficacy and safety of fremanezumab in patients with episodic and chronic migraine with documented inadequate response to 2 to 4 classes of migraine preventive medications over 6 months of treatment i	228
Two-year effectiveness of erenumab in resistant chronic migraine: a prospective real-world analysis	148
The International Headache Congress – IHS and EHF joint congress 2021: late breaking abstracts	108
Calcitonin gene-related peptide-targeting drugs and Raynaud’s phenomenon: a real-world potential safety signal from the WHO pharmacovigilance database	103
Development and validation of a novel model for characterizing migraine outcomes within real-world data	96
Real-World experience of interictal burden and treatment in migraine: a qualitative interview study	94
Episodic headache with spontaneous hypothermia reveal Shapiro’s syndrome variant with effectiveness of clonidine therapy	86
Role of CGRP pathway polymorphisms in migraine: a systematic review and impact on CGRP mAbs migraine therapy	78
Tracking tDCS induced grey matter changes in episodic migraine: a randomized controlled trial	71
CGRP-dependent sensitization of PKC-δ positive neurons in central amygdala mediates chronic migraine	63
Interictal osmophobia is associated with longer migraine disease duration	61
MAB-MIG: registry of the spanish neurological society of erenumab for migraine prevention	59
Galcanezumab effect on “whole pain burden” and multidimensional outcomes in migraine patients with previous unsuccessful treatments: a real-world experience	56
Migraine susceptibility is modulated by food triggers and analgesic overuse via sulfotransferase inhibition	55
Altered functional connectivity of the right caudate nucleus in chronic migraine: a resting-state fMRI study	53
Deterioration of headache impact and health-related quality of life in migraine patients after cessation of preventive treatment with CGRP(−receptor) antibodies	51
Migraine-relevant sex-dependent activation of mouse meningeal afferents by TRPM3 agonists	50
The headache registry of the German Migraine and Headache Society (DMKG): baseline data of the first 1,351 patients	50
The economic and personal burden of cluster headache: a controlled cross-sectional study	47
Long term evaluation of a multidisciplinary trigeminal neuralgia service	47
Altered effective connectivity in migraine patients during emotional stimuli: a multi-frequency magnetoencephalography study	47
Interleukin-6 induces spatially dependent whole-body hypersensitivity in rats: implications for extracephalic hypersensitivity in migraine	46
Anti-CGRP monoclonal antibodies in chronic migraine with medication overuse: real-life effectiveness and predictors of response at 6 months	46
Enhanced functional connectivity between habenula and salience network in medication-overuse headache complicating chronic migraine positions it within the addiction disorders: an ICA-based resting-st	44

Altered speech patterns in subjects with post-traumatic headache due to mild traumatic brain injury	44
Sphingosine-1 phosphate receptor 1 contributes to central sensitization in recurrent nitroglycerin-induced chronic migraine model	43
Migraine patients in Germany - need for medical recognition and new preventive treatments: results from the PANORAMA survey	41
Shift from high-frequency to low-frequency episodic migraine in patients treated with Galcanezumab: results from two global randomized clinical trials	40
Osmophobia in primary headache patients: associated symptoms and response to preventive treatments	40
Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance	39
Whole-brain morphological alterations associated with trigeminal neuralgia	39
Cerebral perfusion variance in new daily persistent headache and chronic migraine: an arterial spin-labeled MR imaging study	37
Single-Pulse Transcranial Magnetic Stimulation for the preventive treatment of difficult-to-treat migraine: a 12-month prospective analysis	37
Correction to: Migraine-relevant sex-dependent activation of mouse meningeal afferents by TRPM3 agonists	37
Correction to: Burden of migraine and unmet needs from the patients’ perspective: a survey across 11 specialized headache clinics in Korea	36