OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Physiology and Biochemistry is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Pyroptosis in inflammation-related respiratory disease	48
The role of anthocyanins as antidiabetic agents: from molecular mechanisms to in vivo and human studies	43
Baicalin suppresses renal fibrosis through microRNA-124/TLR4/NF-κB axis in streptozotocin-induced diabetic nephropathy mice and high glucose-treated human proximal tubule epithelial cells	38
Pyroptosis in stroke-new insights into disease mechanisms and therapeutic strategies	36
The role of protein tyrosine phosphatase 1B (PTP1B) in the pathogenesis of type 2 diabetes mellitus and its complications	34
Effects of gut microbiota–derived extracellular vesicles on obesity and diabetes and their potential modulation through diet	30
Metabolically healthy obesity and metabolically obese normal weight: a review	28
A current view of molecular dissection in autophagy machinery	28
Role of miRNAs in the pathogenesis of T2DM, insulin secretion, insulin resistance, and β cell dysfunction: the story so far	26
Exosome-derived SNHG16 sponging miR-4500 activates HUVEC angiogenesis by targeting GALNT1 via PI3K/Akt/mTOR pathway in hepatocellular carcinoma	24
Regulation of peroxisome proliferator-activated receptor-gamma activity affects the hepatic stellate cell activation and the progression of NASH via TGF-β1/Smad signaling pathway	23
Concurrent vitamin D supplementation and exercise training improve cardiac fibrosis via TGF-β/Smad signaling in myocardial infarction model of rats	21
FTO inhibits oxidative stress by mediating m6A demethylation of Nrf2 to alleviate cerebral ischemia/reperfusion injury	21
Autophagy blockage promotes the pyroptosis of ox-LDL-treated macrophages by modulating the p62/Nrf2/ARE axis	20
Exosomal transfer of circ_0006174 contributes to the chemoresistance of doxorubicin in colorectal cancer by depending on the miR-1205/CCND2 axis	20
Procyanidin A1 alleviates DSS-induced ulcerative colitis via regulating AMPK/mTOR/p70S6K-mediated autophagy	20
Gender-associated differences in oral microbiota and salivary biochemical parameters in response to feeding	19
Emerging roles of microRNAs in intestinal ischemia/reperfusion–induced injury: a review	19
Extracellular vesicles and exosome: insight from physiological regulatory perspectives	19
Posttranslational modification of pyruvate kinase type M2 (PKM2): novel regulation of its biological roles to be further discovered	18
Long non-coding RNA CRNDE promotes malignant progression of hepatocellular carcinoma through the miR-33a-5p/CDK6 axis	18
Maresin 1 regulates insulin signaling in human adipocytes as well as in adipose tissue and muscle of lean and obese mice	18
Adiponectin and leptin exert antagonizing effects on proliferation and motility of papillary thyroid cancer cell lines	18
The potentials of distinct functions of autophagy to be targeted for attenuation of myocardial ischemia/reperfusion injury in preclinical studies: an up-to-date review	18
miR-124-3p targeted SIRT1 to regulate cell apoptosis, inflammatory response, and oxidative stress in acute myocardial infarction in rats via modulation of the FGF21/CREB/PGC1α pathway	17

Downregulation of fatty acid oxidation by involvement of HIF-1α and PPARγ in human gastric adenocarcinoma and related clinical significance	17
Hypoxia: molecular pathophysiological mechanisms in human diseases	17
miRNA signatures in diabetic retinopathy and nephropathy: delineating underlying mechanisms	16
Detrimental effects of hypoxia on glomerular podocytes	16
Inhibition of HMGB1 reduced high glucose-induced BMSCs apoptosis via activation of AMPK and regulation of mitochondrial functions	16
Potential roles of bone morphogenetic protein-9 in glucose and lipid homeostasis	15
MicroRNAs sequencing of plasma exosomes derived from patients with atrial fibrillation: miR-124-3p promotes cardiac fibroblast activation and proliferation by regulating AXIN1	15
Astaxanthin attenuates hepatic steatosis in high-fat diet-fed rats by suppressing microRNA-21 via transactivation of nuclear factor erythroid 2-related factor 2	14
Lactosylceramide induced by elastin-derived peptides decreases adipocyte differentiation	14
Metabolic dysfunction–associated fatty liver disease (MAFLD): an update of the recent advances in pharmacological treatment	14
Obesity of mice lacking VAP-1/SSAO by Aoc3 gene deletion is reproduced in mice expressing a mutated vascular adhesion protein-1 (VAP-1) devoid of amine oxidase activity	14
miR-155 activates the NLRP3 inflammasome by regulating the MEK/ERK/NF-κB pathway in carotid atherosclerotic plaques in ApoE−/− mice	13
LncRNA AFAP1-AS1 promotes M1 polarization of macrophages and osteogenic differentiation of valve interstitial cells	12
Metformin reverses the effects of high glucose on human dermal fibroblasts of aged skin via downregulating RELA/p65 expression	12
Strictosamide alleviates the inflammation in an acute ulcerative colitis (UC) model	12
Retinoprotective effect of agmatine in streptozotocin-induced diabetic rat model: avenues for vascular and neuronal protection	12
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction	12
In the shadow of resveratrol: biological activities of epsilon-viniferin	11
Role of the microRNA-29 family in myocardial fibrosis	11
High expression of NEK2 promotes gastric cancer progression via activating AKT signaling	11
Inflammation and oxidative stress, the links between obesity and COVID-19: a narrative review	10
Benefits, mechanisms, and risks of intermittent fasting in metabolic syndrome and type 2 diabetes	10
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways	10
Autophagy plays a double-edged sword role in liver diseases	10
Inhibitor of growth 2 regulates the high glucose-induced cell cycle arrest and epithelial-to-mesenchymal transition in renal proximal tubular cells	10
miR-455-5p regulates atrial fibrillation by targeting suppressor of cytokines signaling 3	9
FOXA2 inhibits doxorubicin-induced apoptosis via transcriptionally activating HBP rate-limiting enzyme GFPT1 in HCC cells	9
Estrogen alleviates hepatocyte necroptosis depending on GPER in hepatic ischemia reperfusion injury	9
Structure, regulation, and physiological functions of NADPH oxidase 5 (NOX5)	9
HIF-1 signaling: an emerging mechanism for mitochondrial dynamics	9
HIIT and MICT attenuate high-fat diet-induced hepatic lipid accumulation and ER stress via the PERK-ATF4-CHOP signaling pathway	9
AMPKα2 deficiency exacerbates hypoxia-induced pulmonary hypertension by promoting pulmonary arterial smooth muscle cell proliferation	9
Role of serine protease inhibitor, ulinastatin, in rat model of hepatic encephalopathy: aquaporin 4 molecular targeting and therapeutic implication	9
Vaspin attenuates steatosis-induced fibrosis via GRP78 receptor by targeting AMPK signaling pathway	9
α2,6-Sialylation promotes hepatocellular carcinoma cells migration and invasion via enhancement of nSmase2-mediated exosomal miRNA sorting	9
Circadian rhythm disorder: a potential inducer of vascular calcification?	8
Hippo pathway effectors YAP and TAZ and their association with skeletal muscle ageing	8
Cholecystectomy as a risk factor for metabolic dysfunction-associated fatty liver disease: unveiling the metabolic and chronobiologic clues behind the bile acid enterohepatic circulation	8
Stroma-targeting strategies in pancreatic cancer: a double-edged sword	8
Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway	7
Antidiabetic and anti-obesity properties of a polyphenol-rich flower extract from Tagetes erecta L. and its effects on Caenorhabditis elegans fat storages	7
Melatonin modulates proliferation of pancreatic stellate cells through caspase-3 activation and changes in cyclin A and D expression	7
Swimming exercise versus L-carnosine supplementation for Alzheimer’s dementia in rats: implication of circulating and hippocampal FNDC5/irisin	7
Effects of high-intensity interval training on gut microbiota profiles in 12 months’ old ICR mice	7
The serum uric acid/creatinine ratio is associated with nonalcoholic fatty liver disease in the general population	7
MicroRNA-451a attenuates angiotensin II–induced cardiac fibrosis and inflammation by directly targeting T-box1	7
Extracellular vesicular lncRNA FAL1 promotes hepatocellular carcinoma cell proliferation and invasion by inducing macrophage M2 polarization	7
The progress of research on histone methylation in ischemic stroke pathogenesis	7