Drugs & Aging

Article	Citations
Topical Medications for Chronic Itch in Older Patients: Navigating a Pressing Need	98
Metformin: An Old Drug with New Tricks—Promising Role in Vascular Aging and Cardioprotection	68
Association between the Use of Suvorexant and Hip Fracture in Older Adults in Japan Using a Nationwide Administrative Claims Database: A Matched Case–Control Study	61
Real-World Drug Survival of Biologics and Targeted Synthetic Disease-Modifying Anti-rheumatic Drugs Among Patients with Psoriatic Arthritis	48
Perioperative Anticholinergic Medication Use and Incident Dementia among Older Surgical Patients: a Retrospective Cohort Study using Real-World Data	46
Seborrheic Dermatitis in Older Adults: Pathogenesis and Treatment Options	46
Symptoms of Orthostatic Hypotension and Drugs Affecting Autonomic Function are Associated with the Onset of Frailty in Community-Dwelling Persons Aged 80 Years and Above: A Prospective Observational S	45
Anticholinergic Exposure, Drug Dose and Postoperative Delirium: Comparison of Dose-Related and Non-Dose-Related Anticholinergic Burden Scores in a Retrospective Cohort Study of Older Orthopaedic and T	44
The Aging Patient with Cystic Fibrosis	43
Prevalence of Self-Reported Adverse Effects to Cannabis by Older Canadians: A Cross-Sectional Analysis	42
Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care	38
Ulcerative Colitis in Adulthood and in Older Patients: Same Disease, Same Outcome, Same Risks?	37
Changes in Medication Complexity and Post-Hospitalization Outcomes in Older Adults Hospitalized for Heart Failure	35
Safety Study of Anticoagulants for Preventing Deep Venous Thrombosis after Intracerebral Hemorrhage: Data from the Chinese Stroke Center Alliance	34
The Difficulties of Managing Pain in People Living with Frailty: The Potential for Digital Phenotyping	34
Serum Concentration of Apixaban in Relation to Renal Function in Older Hospitalized Patients	33
Pilocarpine in the Treatment of Presbyopia: Progress, Issues, and Future Prospects	32
Psychotropic Medication Prescribing to Patients with Dementia Admitted to Acute Hospitals in Ireland	31
Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing	30
Difficult-to-Treat Rheumatoid Arthritis in Older Adults: Implications of Ageing for Managing Patients	26
Time-Varying Use of Proton Pump Inhibitors and Cognitive Impairment and Dementia: A Real-World Analysis from Germany	26
Correction: Treating Lower Urinary Tract Symptoms in Older Adults: Intravesical Options	24
Patient-Centric Approach for the Treatment of Rheumatoid Arthritis-Associated Interstitial Lung Disease in Older People	24
Prescription and Non-prescription Medication Pill Burdens and Their Associations with Health-Related Quality of Life in Older Adults: A Cross-Sectional Study	23
Utility of Big Data to Explore Medication Adherence in Māori and Non-Māori Community-Dwelling Older Adults with Heart Failure in Aotearoa New Zealand: A Cross-sectional Study	23

Safety and Efficacy of Cenobamate for the Treatment of Focal Seizures in Older Patients: Post Hoc Analysis of a Phase III, Multicenter, Open-Label Study	23
The PROMISING Project: A Pilot Study to Improve Geriatric Care Through a Pharmacist-Led Psychotropic Stewardship Program	21
Associations Between Midlife Anticholinergic Medication Use and Subsequent Cognitive Decline: A British Birth Cohort Study	20
Development of a Predictive Model for Potentially Inappropriate Medications in Older Patients with Cardiovascular Disease	20
International Deprescribing Guidelines Did Not Impact Actual Practice in Deprescribing of Potentially Inappropriate Medications for Nursing Home Residents: An Interrupted Time Series Analysis	18
Exploring Sex, Gender, and Gender-Related Sociocultural Factors in Clinical Decision-Making for Older Adults Using a Prescribing Cascade Vignette: A Transnational Qualitative Study	18
Classifying Polypharmacy According to Pharmacotherapeutic and Clinical Risks in Older Adults: A Latent Class Analysis in Quebec, Canada	17
Correction to: Assessment of Comorbidity Burden and Treatment Response: Reanalysis of the SCD-HEFT Trial	16
Exploring Hyperkalemia Risk in Frail Older Patients Using RAAS Inhibitors	16
Reduced-Dose Edoxaban in Patients Aged ≥ 80 Years: A Single-Center Real-World Analysis	16
Methodological Considerations for Describing Medication Changes in Relation to Clinical Events and Death: An Applied Example in Patients with Type 2 Diabetes and Cancer	16
The Relationship Between Antipsychotics, Cognitive Enhancers, and Major Adverse Cardiovascular/Cerebrovascular Events (MACCE) in Older Adults with Behavioral and Psychological Symptoms of Dementia	16
New Migraine Drugs for Older Adults	15
The Current Landscape of Pharmacotherapies for Sarcopenia	15
Trends in Drug Duplications in Swedish Older Adults: A Nationwide Register Study from 2006 to 2021	15
Exploring Transplant Medication-Taking Behaviours in Older Adult Kidney Transplant Recipients: A Qualitative Study of Semi-Structured Interviews	15
How Should Clinicians Discuss Deprescribing with Caregivers of Older Adults Living with Dementia? A Qualitative Study	15
Antihypertensive Drugs and Risk of Bone Fractures	15
Rosacea in Older Adults and Pharmacologic Treatments	14
Modifiable Determinants of Satisfaction with Intravitreal Treatment in Patients with Neovascular Age-Related Macular Degeneration	14
Anti-hypertensive Drug Classes and Risk of New-Onset Atrial Fibrillation in Healthy Older Adults: A Post Hoc Analysis of ASPREE Trial	14
Incident Functional Limitations Among Community-Dwelling Adults Using Opioids: A Retrospective Cohort Study Using a Propensity Analysis with the Health and Retirement Study	13
Frailty and Potentially Inappropriate Prescribing in Older People with Polypharmacy: A Bi-Directional Relationship?	13
Effect of Information Intervention on Prescribing Practice for Neuropathic Pain in Older Patients: A Nationwide Register-Based Study	13
Authors’ Reply to Langford et al.: “Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing”	13
Renal Function, Cardiovascular Diseases, Appropriateness of Drug Prescription and Outcomes in Hospitalized Older Patients	12
Optimizing Reversal of Neuromuscular Block in Older Adults: Sugammadex or Neostigmine	12
Characteristics of Late-Onset Systemic Lupus Erythematosus: Clinical Manifestations and Diagnostic and Treatment Challenges	12
Menopause, Hormone Therapy, and Gout in Older Women: An Overlooked Connection	12
Comment on “The Relationship Between Antipsychotics, Cognitive Enhancers, and Major Adverse Cardiovascular/Cerebrovascular Events (MACCE) in Older Adults with Behavioral and Psychological Symptoms of	12
Antidepressants to Manage Osteoarthritic Pain: The Value of Pain Phenotyping	11
Use of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees	11
Medical Cannabis Use Among Older Adults in Canada: Self-Reported Data on Types and Amount Used, and Perceived Effects	10
Prescription Opioid Use in Older Adults: Trends and Changes in New and Long-Term Use in the United States, 2013–2020	10
Elevating Safe Use of Over-The-Counter Medications in Older Adults: A Narrative Review of Pharmacy Involved Interventions and Recommendations for Improvement	10
The Association of Gabapentin Initiation with Cognitive and Behavioral Changes in Older Adults with Cognitive Impairment: A Retrospective Cohort Study	10
The FORTA (Fit for the Aged) List 2024: Fifth Version of a Validated Clinical Aid for Improved Pharmacotherapy in Older Adults	10
Association Between Gabapentinoid Use and Changes in Claims-Based Frailty Among Long-Term Opioid Users	10
The Prognostic Utility of Anticholinergic Burden Scales: An Integrative Review and Gap Analysis	10
Unlocking Deprescribing Potential in Nursing Homes: Insights from a Focus Group Study with Healthcare Professionals	10
Pain in Osteoporosis: Current and Future Strategies	10
Fall-Risk-Increasing Drugs and Gait Performance in Community-Dwelling Older Adults: Exploratory Results from the Gait and Brain Study	10
Anesthesia Considerations in Older Adults Undergoing Emergency Mechanical Thrombectomy for Acute Ischaemic Stroke	9
Inclusion of Older Adults in Early-Phase Cancer Clinical Trials: Safety, Efficacy and a Way Forward	9
Management of Scleritis in Older Adults	9
Do Proton Pump Inhibitors Reduce Upper Gastrointestinal Bleeding in Older Patients with Atrial Fibrillation Treated with Oral Anticoagulants? A Nationwide Cohort Study in France	9
Toxicity in Older Patients with Cancer Receiving Immunotherapy: An Observational Study	9
Rho Kinase Inhibitors: Strategies in Glaucoma Treatment in Older Adults	9
From Drugs to Dry Mouth: A Systematic Review Exploring Oral and Psychological Health Conditions Associated with Dry Mouth in Older Adults with Polypharmacy	9
Minimising Harm and Managing Pain: Deprescribing Opioids in Older Adults	9

Benzodiazepine Receptor Agonists Use and Cessation Among Multimorbid Older Adults with Polypharmacy: Secondary Analysis from the OPERAM Trial	9
Comparison of Anticholinergic Burden Scales and Their Association with Cognitive and Functional Impairment in Older Adults: A Cross-Sectional Study Using the REPOSI Database	8
Associated Factors to Efficacy and Tolerance of Immunotherapy in Older Patients with Cancer Aged 70 Years and Over: Impact of Coprescriptions	8
Pharmacological Treatments for Presbyopia	8
Factors Influencing Hospital Physicians’ Recognition of Prescribing Cascades: A Qualitative Interview Study	8
Initial Real-World Evidence for Lecanemab in the United States	8
Prospective Observational Study Evaluating the Prognostic Value of the G8 Screening Tool for Extensive-Stage Small Cell Lung Cancer Patients Who Received Programmed Death-Ligand 1 Inhibitor plus Plati	8
Pharmacological Risk Assessment Among Older Patients with Polypharmacy Using the Clinical Decision Support System Janusmed Risk Profile: A Cross-Sectional Register Study	8
Aging in Granulomatosis with Polyangiitis and Microscopic Polyangiitis: From Pathophysiology to Clinical Management	8
A Proactive Approach to Prevent Hematopoietic Exhaustion During Cancer Chemotherapy in Older Patients: Temporary Cell-Cycle Arrest	8
Deprescribing Medications that Increase the Risk of Falls in Older People: Exploring Doctors' Perspectives Using the Theoretical Domains Framework (TDF)	8
A Motivational Interviewing Intervention to Improve Adherence to ACEIs/ARBs among Nonadherent Older Adults with Comorbid Hypertension and Diabetes	8
Secular Trends in Central Nervous System-Active Polypharmacy Among Serial Cross-Sections of US Adults, 2009–2020	8
Patient-Reported Outcomes in Geriatric Oncology—Balancing Quality of Life and Therapeutic Effectiveness Using Primary Breast Cancer as a Model	7
Correction: Burden of Disease and Treatment Gap in Patients with an Osteoporotic Hip Fracture between 2015 and 2019 in Italy	7
Ageing with HIV: Medicine Optimisation Challenges and Support Needs for Older People Living with HIV: A Systematic Review	7
Prevention of Chemotherapy-Induced Nausea and Vomiting in the Older Patient: Optimizing Outcomes	7
Polypharmacy and Aging in People Living with HIV: 6 Years of Experience in a Multidisciplinary Outpatient Clinic	7
Optimizing Prevention of Recurrent Urinary Tract Infections in Older Patients with Frailty	7
Drugs and Healthy Aging	7
Correction to: Prevalence and factors associated with inappropriate dosing of apixaban and rivaroxaban in hospitalized older adults with atrial fibrillation: a cross‑sectional study	7
Current Pharmacological Therapies for the Management of Spondyloarthritis: Special Considerations in Older Patients	7
Hypotension Under Antihypertensive Treatment and Incident Hospitalizations of Nursing Home Residents	7
Treating Hypercholesterolemia in Older Adults for Primary Prevention of Cardiovascular Events	7
Managing Gout in Patients with Metabolic Syndrome	7
Influenza and Aging: Clinical Manifestations, Complications, and Treatment Approaches in Older Adults	7
Benefit–Risk Assessment of Psychotropic Drugs in Older Patients with Chronic Obstructive Pulmonary Disease	7
A 12-Year Retrospective Study of the Prevalence of Anticholinergic Polypharmacy and Associated Outcomes Among Medicare Patients with Overactive Bladder in the USA	7
NSAIDs for Pain Control During the Peri-Operative Period of Hip Fracture Surgery: A Systematic Review	7
Efficacy and Safety of Dupilumab in the Treatment of Refractory Atopic Dermatitis in Older Adults: A Retrospective, Single-Center Study	7
Efficacy and Safety of Dupilumab in Older Patients (Aged 80 Years and Above) with Atopic Dermatitis: A Prospective Study	7
The Prevalence of Adverse Drug Reactions and Adverse Drug Events from Heart Failure Medications in Frail Older Adults: A Systematic Review	7
Efficacy and Safety of 7-Day Non-Bismuth Concomitant Quadruple Therapy for First-Line Helicobacter pylori Eradication in the Elderly	6
Predictors and Moderators of Hospitalisation and Mortality in People with Dementia Using Antipsychotics: Systematic Review	6
Frequency and Acceptance of Clinical Decision Support System-Generated STOPP/START Signals for Hospitalised Older Patients with Polypharmacy and Multimorbidity	6
Polypharmacy and Antibody Response to SARS-CoV-2 Vaccination in Residents of Long-Term Care Facilities: The GeroCovid Vax Study	6
Validation of MyFORTA: An Automated Tool to Improve Medications in Older People Based on the FORTA List	6
Systematic Review and Meta-analysis of Interventions to Reduce Adverse Drug Reactions in Older Adults: An Update	6
Impact of a Comprehensive Intervention Bundle Including the Drug Burden Index on Deprescribing Anticholinergic and Sedative Drugs in Older Acute Inpatients: A Non-randomised Controlled Before-and-Afte	6
Low-Dose Glucocorticoids in Older Patients with Rheumatoid Arthritis: What Does the Evidence Say?	6
Testosterone Therapy in Older Men: Present and Future Considerations	6
Prevention of Chronic Kidney Disease and Its Complications in Older Adults	6
Chronic Urticaria in Older Adults: Treatment Considerations	6
Efficacy and safety of insomnia treatment with lemborexant in older adults: analyses from three clinical trials	6
Hallucinations, Antipsychotic Use, and Mortality in Older Adults with Dementia: Retrospective Cohort Study of Two Medicare-Linked National Health Surveys	6
Anesthesia and Sedation in Older Adults with Pre-existing Cognitive Impairment	6
Potentially Inappropriate Psychotropic Drugs in Nursing Homes: An Italian Observational Study	6
Safety of Low-Dose Quetiapine for Insomnia in Older Adults	6
Temporal Trends Over Two Decades in the Use of Anticholinergic Drugs Among Older Community-Dwelling People in Helsinki, Finland	5
The FORTA (Fit fOR The Aged) List 2021: Fourth Version of a Validated Clinical Aid for Improved Pharmacotherapy in Older Adults	5
Current Therapies and Drug Development Pipeline in Lewy Body Dementia: An Update	5
Medication Complexity Among Older Adults with HF: How Can We Assess Better?	5
Safety and Tolerability of Antimicrobial Agents in the Older Patient	5
Crushed Tablet Administration for Patients with Dysphagia and Enteral Feeding: Challenges and Considerations	5
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders	5
Decreased Kidney Function Explains Higher Vancomycin Exposure in Older Adults	5
Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models	5
One-Year Survival and Postoperative Complications in Older Patients with Intertrochanteric Fractures: Association with Polypharmacy—A Multicenter Retrospective Cohort Study	5
Association of Antipsychotic Dose with Surrogate Efficacy and Safety Outcomes in Hospitalized Older Adults: A Retrospective Cohort Study	5
Prescribing Appropriate Medicines to Older Adults: A Finnish Experience with the Web-Based Meds75+ Database	5
Risk factors predictive of adverse drug events and drug-related falls in aged care residents: secondary analysis from the ReMInDAR trial	5
Using Medication Dispensation Data to Identify Clusters with Similar Prescribing Patterns in Older Adults Living with Dementia	5
HOSPITAL Score and LACE Index to Predict Mortality in Multimorbid Older Patients	5
Medicine Optimisation and Deprescribing Intervention Outcomes for Older People with Dementia or Mild Cognitive Impairment: A Systematic Review	5
Individualized Dosing Patterns in the Treatment of Older Patients with Gastrointestinal Stromal Tumors: Results of a Registry-Based Observational National Cohort Study Including 871 Patients	5
Acknowledgement to Referees	4
Assessing Frailty-Specific Treatment Effect in Cardiovascular Disease: A Systematic Review	4
Frailty-Informed Pain Management: A Clinical Imperative Beyond Chronological Age	4
Opioid Prescriptions for Low Back Pain among Military-Connected Older Adults Across Multiple Care Systems	4
Correction to: The FORTA (Fit fOR The Aged) List 2021: Fourth Version of a Validated Clinical Aid for Improved Pharmacotherapy in Older Adults	4
Association of Tumor Necrosis Factor-α Inhibitors with Incident Dementia: Analysis Based on Population-Based Cohort Studies	4
Detection of Potential Prescribing Cascades in Multimorbid Older Patients Hospitalised with Acute Illness—An Observational Prospective Prevalence Study	4
Barriers and Enablers of Healthcare Providers to Deprescribe Cardiometabolic Medication in Older Patients: A Focus Group Study	4
Pain Management in Older Adults with Chronic Wounds	4
Dementia Medications and Their Association with Pain Medication Use in Medicare Beneficiaries with Alzheimer’s Disease/Alzheimer’s Disease-Related Dementias and Chronic Pain	4
Patterns and Characteristics of Gabapentin Use Among Medicare Beneficiaries	4
Acknowledgement to Referees	4
Independent Association Between Use of Proton Pump Inhibitors and Muscle Wasting in Patients with Heart Failure: A Single-Center, Ambispective, Observational Study	4
The Impact of Polypharmacy on Management of Lower Urinary Tract Symptoms in Parkinson’s Disease	4
Depression in Patients with Parkinson’s Disease: Current Understanding of its Neurobiology and Implications for Treatment	4

Deprescribing for People with Dementia: A Roadmap	4
Development of a Frailty Screening Tool Using Electronic Community Pharmacy Records	4
Executive Summary: Treatment of Osteoporosis and Osteoarthritis in the Oldest Old	4
Opioid Initiation and the Hazard of Falls or Fractures Among Older Adults with Varying Levels of Central Nervous System Depressant Burden	4
Association of Psychotropic Education with Quality of Life: A Before-After Study in Residential Aged Care Facilities	4
Onychomycosis in Older Adults: Prevalence, Diagnosis, and Management	3
Use of Psychedelic Agents in Older Adults with Treatment-Resistant Major Depressive Disorder: What the Evidence Shows	3
Association of Potentially Inappropriate Medication Classes with Mortality Risk Among Older Adults Initiating Hemodialysis	3
Amyloid-related Imaging Abnormalities (ARIA) in the Context of Alzheimer’s Disease and Amyloid-targeting Therapies: An Introduction for Advanced Practice Providers	3
Impact of Disease-Modifying Antirheumatic Drugs on Cognitive Function in Older Adults with Rheumatoid Arthritis	3
Interprofessional Interventions Involving Pharmacists and Targeting the Medicines Management Process Provided to Older People Residing in Nursing Homes: A Systematic Review and Meta-Analysis of Random	3
Basal Insulin and GLP-1 Receptor Agonist Combination Therapy in Frail Older Inpatients: A Real-World Observational Study	3
The Information-Seeking Behavior and Unmet Knowledge Needs of Older Medicinal Cannabis Consumers in Canada: A Qualitative Descriptive Study	3
Trajectories of Benzodiazepine Use among Older Adults from a Concordance-with-Guidelines Perspective: A Nationwide Cohort Study	3
A Systematic Review of the Current Evidence from Randomised Controlled Trials on the Impact of Medication Optimisation or Pharmacological Interventions on Quantitative Measures of Cognitive Function i	3
Exploring Antipsychotic Use for Delirium Management in Adults in Hospital, Sub-Acute Rehabilitation and Aged Care Settings: A Systematic Literature Review	3
Deprescribing Antipsychotics and Proton Pump Inhibitors in Long-Term Care: A Prescribing Portraits Approach	3
One-Year Mortality in Hospitalized, Frail Older Adults with Atrial Fibrillation on Oral Anticoagulant Therapy: Impact of Stroke and Bleeding Events	3
Benefit–Risk Assessment of Rivaroxaban in Older Patients With Nonvalvular Atrial Fibrillation or Venous Thromboembolism	3
The Incidence of Myocarditis Following an Influenza Vaccination: A Population-Based Observational Study	3
Antihypertensive Use and the Risk of Alzheimer’s Disease and Related Dementias among Older Adults in the USA	3
Healthcare Costs Associated with Potentially Inappropriate Medication Prescribing Detected by Computer Algorithm Among Older Patients	3
Still’s Disease Onset in Older Adults: Clinical Features, Diagnosis, and Management	3
Pharmacotherapies in Older Adults with COPD: Challenges and Opportunities	3
Sacubitril/Valsartan Reduces the Risk of All-Cause Dementia in Patients with Heart Failure: A Systematic Review and Meta-Analysis	3
Medication Use and Quality of Life in Older Adults with Personality Disorders	3
Cross-Cultural Adaptation and Clinical Validation of TIME Criteria to Detect Potentially Inappropriate Medication Use in Older Adults: Methodological Report from the TIME International Study Group	3
Measuring Quality of Life in Deprescribing Trials: A Scoping Review	3
Toxicity of Cancer Immunotherapies in Older Patients: Does Age Make a Difference?	3
Pharmacological Management of IgG4-Related Disease: From Traditional to Mechanism-Based Targeted Therapies	3
Cutaneous Lupus Erythematosus: Review and Considerations for Older Populations	3
Guideline-Directed Medical Therapies for Heart Failure with a Reduced Ejection Fraction in Older Adults: A Narrative Review on Efficacy, Safety and Timeliness	3
Current Management of Hypertension in Older Adults	3
A Review of Therapeutics for Treatment-Resistant Depression in the Older Adult	3
Factors Influencing General Practitioners’ Deprescribing Decisions for Older Adults, with Insights into Frailty: a Qualitative Study in Greek Primary Care	3
Evaluating Provider and Pharmacy Discordance in Potential Calcium Channel Blocker–Loop Diuretic Prescribing Cascade	3