Molecular Diagnosis & Therapy

Papers
(The median citation count of Molecular Diagnosis & Therapy is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
The Role of [18F]F-FDG PET/CT for Predicting Histology and Prognosis in Patients with Thymic Lesions117
Real-World Evidence of the Prevalence of Driver Mutations in Anorectal Melanoma73
The Complement System and C4b-Binding Protein: A Focus on the Promise of C4BPα as a Biomarker to Predict Clopidogrel Resistance66
Validation of HER2 Status in Whole Genome Sequencing Data of Breast Cancers with the Ploidy-Corrected Copy Number Approach52
Evaluation of the Suitability of RNAscope as a Technique to Measure Gene Expression in Clinical Diagnostics: A Systematic Review52
RNA Sequencing Data from Human Intracranial Aneurysm Tissue Reveals a Complex Inflammatory Environment Associated with Rupture46
Diagnostic Accuracy of Two Molecular Tools for Diagnosis of Congenital Chagas Disease43
The Road Traveled and Journey Ahead for the Genetics and Genomics of Tinnitus38
Single Nucleotide Variants in KIF14 Gene May Have Prognostic Value in Breast Cancer37
Candidate MicroRNA Biomarkers in Lupus Nephritis: A Meta-analysis of Profiling Studies in Kidney, Blood and Urine Samples35
Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option34
Genetic Alterations of Melanoma Brain Metastases: A Systematic Review and Meta-Analysis32
Pitfalls in Cutaneous Melanoma Diagnosis and the Need for New Reliable Markers31
Single-Cell Sequencing in Neurodegenerative Disorders30
The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta-analysis28
Predictive Ability of Serum Amino Acid Levels to Differentiate Fibromyalgia Patients from Healthy Subjects28
ADORA3: A Key Player in the Pathogenesis of Intracranial Aneurysms and a Potential Diagnostic Biomarker26
Identification of Plasmatic MicroRNA-206 as New Predictor of Early Recurrence of Atrial Fibrillation After Catheter Ablation Using Next-generation Sequencing25
Multicenter Performance Evaluation of the Revogene® GBS DS Real-Time PCR Assay for Group B Streptococcus Detection During Labor22
Decoding Molecular Mechanisms Underlying Outcomes After Ischemic Stroke Thrombectomy by RNA Sequencing of Retrieved Clots22
Diagnostic Approaches to Investigate JAK2-Unmutated Erythrocytosis Based on a Single Tertiary Center Experience22
MicroRNA-146a Signature in Psoriasis: A Systematic Review and Meta-Analysis20
Beyond Death: Unmasking the Intricacies of Apoptosis Escape20
In vivo LNP-CRISPR Approaches for the Treatment of Hemophilia20
Evaluation of the Oncomine Comprehensive Assay Plus NGS Panel and the OncoScan CNV Assay for Homologous Recombination Deficiency Detection19
Performance of a Rapid Digital PCR Test for the Detection of Non-Small Cell Lung Cancer (NSCLC) Variants19
Correction to: System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration18
Targeted Therapy in Salivary Gland Cancer: Prevalence of a Selected Panel of Actionable Molecular Alterations in a German Tertiary Referral Center Patient Cohort18
Genotype and Phenotype of Renal Hypouricemia: A Single-Center Study from China17
Clinical Validation of a Targeted RNA-Sequencing Assay for Driver Gene Alteration Detection in Non-Small Cell Lung Cancer17
Analytical and Clinical Performance of Droplet Digital PCR in the Detection and Quantification of SARS-CoV-217
Molecular Diagnosis of Inherited Cardiac Diseases in the Era of Next-Generation Sequencing: A Single Center’s Experience Over 5 Years17
Omidubicel: First Approval17
Detecting ALK Rearrangement with RT-PCR: A Reliable Approach Compared with Next-Generation Sequencing in Patients with NSCLC16
Acute Fluid Biomarkers for Diagnosis and Prognosis in Children with Mild Traumatic Brain Injury: A Systematic Review16
The Opportunities and Challenges of Molecular Tagging Next-Generation Sequencing in Liquid Biopsy15
Commercial ctDNA Assays for Minimal Residual Disease Detection of Solid Tumors14
Achromatopsia: Genetics and Gene Therapy14
Internal Standardization of the Interpretation and Reporting of Sequence Variants in Hematologic Neoplasms13
Lutetium Lu 177 Vipivotide Tetraxetan: First Approval13
IDH Inhibitors and Beyond: The Cornerstone of Targeted Glioma Treatment13
Metastasis Prevention: Focus on Metastatic Circulating Tumor Cells13
Longitudinal Relationship between Idylla Plasma ctBRAF V600 Mutation Detection and Tumor Burden in Patients with Metastatic Melanoma13
Prognostic Biomarker-Based Identification of Drugs for Managing the Treatment of Endometrial Cancer12
Proclarix, A New Biomarker for the Diagnosis of Clinically Significant Prostate Cancer: A Systematic Review12
Molecular Therapy for Choroideremia: Pre-clinical and Clinical Progress to Date11
Preimplantation Genetic Testing for Monogenic Conditions: Is Cell-Free DNA Testing the Next Step?11
Prognostic Value of Programmed Death Ligand-1 Expression in Solid Tumors Irrespective of Immunotherapy Exposure: A Systematic Review and Meta-Analysis11
The Value of Pharmacogenetics to Reduce Drug-Related Toxicity in Cancer Patients11
Targeting Mutated KRAS Genes to Treat Solid Tumours11
Biomarkers for Nonexudative Age-Related Macular Degeneration and Relevance for Clinical Trials: A Systematic Review11
Indirect Clinical Validation of a Programmed Death-Ligand 1 Laboratory-Developed Test for Gastric/Gastroesophageal Junction Adenocarcinoma with 22C3 Antibody Concentrate11
Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients11
Follicular T Helper and Breg Cell Balance in Severe Allergic Asthma Before and After Omalizumab Therapy11
Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis11
A Window of Opportunity for Newborn Screening11
Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta-Analysis10
Digital PCR-Based Method for Detecting CDKN2A Loss in Brain Tumours10
Detection of the Copy Number Variants of Genes in Patients with Familial Cardiac Diseases by Massively Parallel Sequencing10
Gene Therapy for Cardiomyocyte Renewal: Cell Cycle, a Potential Therapeutic Target9
Personalized Cancer Monitoring Assay for the Detection of ctDNA in Patients with Solid Tumors9
Gene Therapies in Clinical Development to Treat Retinal Disorders9
Clinical Potential of Expanded Noninvasive Prenatal Testing for Detection of Aneuploidies and Microdeletion/Microduplication Syndromes9
Role of lncRNAs in Remodeling of the Coronary Artery Plaques in Patients with Atherosclerosis9
Is the Homologous Recombination Repair Mutation Defined by a 15-Gene Panel Associated with the Prognosis of Epithelial Ovarian Cancer?9
Urothelial Bladder Cancer: Genomic Alterations in Fibroblast Growth Factor Receptor9
Exploring the Role of HtrA Family Genes in Cancer: A Systematic Review9
Nanocarrier-Mediated Delivery of MicroRNAs for Fibrotic Diseases9
Developing a DNA Methylation Signature to Differentiate High-Grade Serous Ovarian Carcinomas from Benign Ovarian Tumors8
Molecular Therapeutics in Development to Treat Hyperlipoproteinemia8
Identification of Immunodominant Epitopes of Dengue Virus 2 Envelope and NS1 Proteins: Evaluating the Diagnostic Potential of a Synthetic Peptide8
Sensitive and Specific Droplet Digital PCR Assays for Circulating Tumor HPV DNA: Development, Validation, and Clinical Application in HPV-Associated Cancers8
Clinical Exome Reanalysis: Current Practice and Beyond8
Correction to: Molecular Therapeutics in Development to Treat Alzheimer’s Disease8
Comment on “Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta‑Analysis”8
Molecular Dynamic Simulations to Determine Individualized Therapy: Tetrabenazine for the GNAO1 Encephalopathy E246K Variant8
Multicenter In-House Evaluation of an Amplicon-Based Next−Generation Sequencing Panel for Comprehensive Molecular Profiling7
The Metabolic Landscape of Breast Cancer and Its Therapeutic Implications7
Emerging Landscape of SARS-CoV-2 Variants and Detection Technologies7
Mycobacterium tuberculosis Detection Using CRISPR Technology: An Updated Systematic Review and Meta-analysis7
Selecting Targets for Molecular Imaging of Gastric Cancer: An Immunohistochemical Evaluation7
Validation of a Transcriptome-Based Assay for Classifying Cancers of Unknown Primary Origin7
Flotufolastat F 18: Diagnostic First Approval7
Epidermolysis Bullosa: A Review of the Tissue-Engineered Skin Substitutes Used to Treat Wounds7
Immune-Checkpoint Expression on CD4, CD8 and NK Cells in Blood, Bronchoalveolar Lavage and Lymph Nodes of Sarcoidosis7
Smelling the Disease: Diagnostic Potential of Breath Analysis7
Worldwide Prevalence of Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer: A Meta-Analysis7
Saliva Collection Methods Among Children and Adolescents: A Scoping Review6
Elivaldogene Autotemcel: First Approval6
Zevorcabtagene Autoleucel: First Approval6
Evaluation of Factors that Affect the Performance of COVID-19 Molecular Assays Including Presence of Symptoms, Number of Detected Genes and RNA Extraction Type6
Lifileucel: First Approval6
Flow Cytometry of CD5-Positive Hairy Cell Leukemia6
Author’s Reply to ‘‘Comment on ‘Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta-Analysis’’6
Identification of Somatic Genetic Variants in Superficial Vascular Malformations by Liquid Biopsy in a Cohort of 88 Patients from a French Hospital6
Clinical Utility of Implementing a Frontline NGS-Based DNA and RNA Fusion Panel Test for Patients with Suspected Myeloid Malignancies6
The Role οf Ion Channels in the Development and Progression of Prostate Cancer6
Piflufolastat F 18: Diagnostic First Approval6
Expression Signature of Immune-Related MicroRNAs in Autoimmune Skin Disease: Psoriasis and Vitiligo Insights5
Immune Checkpoint Blockade Therapy for Breast Cancer: Lessons from Epithelial–Mesenchymal Transition5
Correction: Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders5
A Prospective Evaluation of the Analytical Performance of GENECUBE® HQ SARS-CoV-2 and GENECUBE® FLU A/B5
Molecular Diagnosis of Primary Cardiomyopathy in 231 Unrelated Pediatric Cases by Panel-Based Next-Generation Sequencing: A Major Focus on Five Carriers of Biallelic TNNI3 Pathogenic Variants5
Luminal Breast Cancer: Risk of Recurrence and Tumor-Associated Immune Suppression5
Prevalence of NTRK Fusions in Canadian Solid Tumour Cancer Patients5
Development of a Novel Internally Controlled HrpB1 Gene-Based Real-Time qPCR Assay for Detection of Burkholderia pseudomallei5
How Do Molecular Classifications Affect the Neoadjuvant Treatment of Muscle-Invasive Urothelial Carcinoma?5
Celomic Fluid: Laboratory Workflow for Prenatal Diagnosis of Monogenic Diseases5
Advances in RNA Viral Vector Technology to Reprogram Somatic Cells: The Paramyxovirus Wave5
Functional Association of miR-133b and miR-21 Through Novel Gene Targets ATG5, LRP6 and SGPP1 in Coronary Artery Disease5
Nucleic Acid Quality Assessment is Critical to the Success of the Oncomine Dx Target Test for Lung Cancer5
Genetic Characterization of a Cohort of Italian Patients with Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency5
Diagnostic Utility of a 90-Gene Expression Assay (Canhelp-Origin) for Patients with Metastatic Cancer with an Unclear or Unknown Diagnosis5
Development and Evaluation of a Droplet Digital PCR Assay for 8p23 β-Defensin Cluster Copy Number Determination5
Genetic Profiling of Diffuse Large B-Cell Lymphoma: A Comparison Between Double-Expressor Lymphoma and Non-Double-Expressor Lymphoma5
Optimization of a Quantitative PCR Methodology for Detection of Aspergillus spp. and Rhizopus arrhizus4
Expanded Alternatives of CRISPR–Cas9 Applications in Immunotherapy of Colorectal Cancer4
Characterization of 13 Novel Genetic Variants in Genes Associated with Epilepsy: Implications for Targeted Therapeutic Strategies4
Introducing Circulating Vasculature-Related Transcripts as Biomarkers in Coronary Artery Disease4
Tumour Marker Expression in Head and Neck Malignancies to Identify Potential Targets for Intraoperative Molecular Near-Infrared Imaging4
Bridging the Gap: Cost-Effective Strategies for Detecting Ph-Like B-Lineage ALL in Resource-Limited Settings4
Serum Levels of miR-146a in Patients with Psoriasis4
The Potential of Nanobodies for COVID-19 Diagnostics and Therapeutics4
Relationship between Proclarix and the Aggressiveness of Prostate Cancer4
Selective Signal Capture from Multidimensional GPCR Outputs with Biased Agonists: Progress Towards Novel Drug Development4
Clinical Performance of the cobas Liat SARS-CoV-2 & Influenza A/B Assay in Nasal Samples4
Tabelecleucel: First Approval4
Long-Read Nanopore Sequencing of RPGR ORF15 is Enhanced Following DNase I Treatment of MinION Flow Cells4
Development of an Affordable ELISA Targeting the SARS-CoV-2 Nucleocapsid and Its Application to Samples from the Ongoing COVID-19 Epidemic in Ghana4
Effect of E-cadherin on Prognosis of Colorectal Cancer: A Meta-Analysis Update4
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