Molecular Diagnosis & Therapy

Papers
(The median citation count of Molecular Diagnosis & Therapy is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
ADORA3: A Key Player in the Pathogenesis of Intracranial Aneurysms and a Potential Diagnostic Biomarker135
Predictive Ability of Serum Amino Acid Levels to Differentiate Fibromyalgia Patients from Healthy Subjects79
The Role of MicroRNAs in the Pathogenesis and as Biomarkers for Pediatric Epilepsy: A Systematic Review79
Comment on “Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta‑Analysis”58
Indirect Clinical Validation of a Programmed Death-Ligand 1 Laboratory-Developed Test for Gastric/Gastroesophageal Junction Adenocarcinoma with 22C3 Antibody Concentrate56
Personalized Cancer Monitoring Assay for the Detection of ctDNA in Patients with Solid Tumors56
Gene Therapy for Cardiomyocyte Renewal: Cell Cycle, a Potential Therapeutic Target41
Expression Signature of Immune-Related MicroRNAs in Autoimmune Skin Disease: Psoriasis and Vitiligo Insights39
Personalized Medicine in Cystic Fibrosis: Characterization of Eight Rare CFTR Variants in Intestinal Organoids and Cellular Models36
Evaluation of Minimal Residual Disease in Patients with Neuroblastoma36
Drug Hypersensitivity Reactions in Patients with Cystic Fibrosis: Potential Value of the Lymphocyte Toxicity Assay to Assess Risk35
FAPI-Targeted Molecular Imaging: Transforming Insights into Post-Ischemic Myocardial Remodeling?35
The Role of Non-coding RNAs in Connective Tissue Diseases: Diagnostic and Therapeutic Potential of miRNAs, lncRNAs and circRNAs34
Research Progress on Signal Conversion Based on Aptamer Combined CRISPR/Cas System in Biosensors32
Correction to: Revakinagene Taroretcel: First Approval31
Prediction of Biomarker Expression on Primary Pancreatic Ductal Adenocarcinoma Tissues Using Fine-Needle Biopsies: Paving the Way for a Patient-Tailored Molecular Imaging Approach31
Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders28
Inflammatory Gene Panel Guiding the Study of Genetics in Inflammatory Bowel Disease26
Fatty Acid Desaturase: The Yin or Yang of Disease Pathology25
Personalizing Oncolytic Immunovirotherapy Approaches24
Glioma 2021 WHO Classification: The Superiority of NGS Over IHC in Routine Diagnostics23
Development of a Nomogram to Predict Therapeutic Resistance in Metastatic Melanoma Using Longitudinal ctDNA Kinetics23
Afamitresgene Autoleucel: First Approval23
Clinical Metagenomic Next-Generation Sequencing for Diagnosis of Central Nervous System Infections: Advances and Challenges23
Long-Range PCR and Nanopore Sequencing Enables High-Throughput Detection of TCF4 Trinucleotide Repeat Expansions in Fuchs Endothelial Corneal Dystrophy22
Comment on “The Diagnostic and Prognostic Value of miR‑155 in Cancers: An Updated Meta‑analysis”22
Advances and Challenges in the Diagnosis of Leishmaniasis22
Transcript-Based Diagnosis and Expanded Phenotype of an Intronic Mutation in TPM3 Myopathy21
Development of a New Rapid Simultaneous Molecular Assay for the Detection of STI Pathogens and Drug Resistance-Associated Mutations20
Molecular Therapeutics in Development to Treat Alzheimer’s Disease19
Diagnosis of Lung Cancer Through Exhaled Breath: A Comprehensive Study19
Advances in Pompe Disease Treatment: From Enzyme Replacement to Gene Therapy18
Single Nucleotide Variants in KIF14 Gene May Have Prognostic Value in Breast Cancer18
Targeted Therapy in Salivary Gland Cancer: Prevalence of a Selected Panel of Actionable Molecular Alterations in a German Tertiary Referral Center Patient Cohort17
Molecular Dynamics as a Precision Therapy: A Perspective on Epileptic Encephalopathies17
In vivo LNP-CRISPR Approaches for the Treatment of Hemophilia17
Performance of a Rapid Digital PCR Test for the Detection of Non-Small Cell Lung Cancer (NSCLC) Variants17
The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta-analysis17
The Emerging Role of Olfactory Receptors: From Genomics to Precision Medicine17
Correction to: Molecular Therapeutics in Development to Treat Alzheimer’s Disease16
Evolutionary Overview and Future Perspectives: ESR1 Mutations, Liquid Biopsy, and Artificial Intelligence for a New Era of Personalized Medicine in ER+ Breast Cancer16
Selecting Targets for Molecular Imaging of Gastric Cancer: An Immunohistochemical Evaluation16
Is the Homologous Recombination Repair Mutation Defined by a 15-Gene Panel Associated with the Prognosis of Epithelial Ovarian Cancer?15
Neuromuscular Junction as a Molecular Target in Sarcopenia: Mechanisms, Therapeutic Strategies, and Future Directions15
Lifileucel: First Approval14
The Role οf Ion Channels in the Development and Progression of Prostate Cancer14
Role of lncRNAs in Remodeling of the Coronary Artery Plaques in Patients with Atherosclerosis14
Diagnostic Performance of the ASCL1/ZNF582 Methylation Test for Detection of High-Grade Vulvar Intraepithelial Neoplasia and Vulvar Cancer14
TROP2-Targeted Therapeutics in Development to Treat Gastrointestinal Tumors14
Correction: Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders14
Cell-Free HPV-DNA in Screening, Diagnosis, Prognosis, and Treatment Response Monitoring of Cervical Cancer14
Cytokines at the Crossroads of Mitochondrial Dysfunction and Inflammation in Colorectal Cancer: Implications for Postoperative Complications13
Psoriasis: A Multidimensional Review of Onset, Progression, Treatment, and the Evolution of Disease Models13
Bridging the Gap: Cost-Effective Strategies for Detecting Ph-Like B-Lineage ALL in Resource-Limited Settings13
Comment on “Prognostic Value of Programmed Death Ligand-1 Expression in Solid Tumors Irrespective of Immunotherapy Exposure: A Systematic Review and Meta‑Analysis”13
Correction to: Optimization of a Quantitative PCR Methodology for Detection of Aspergillus spp. and Rhizopus arrhizus12
Emerging RNAi Therapies to Treat Hypertension12
Correction to: Exploratory Prognostic Biomarkers of Complement-Mediated Thrombotic Microangiopathy (CM-TMA) in Adults with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of a Phase III Study of R12
Exploratory Prognostic Biomarkers of Complement-Mediated Thrombotic Microangiopathy (CM-TMA) in Adults with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of a Phase III Study of Ravulizumab11
Obecabtagene Autoleucel: First Approval11
Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of “Second Hit” in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma11
Future Prospects for Epigenetics in Autism Spectrum Disorder11
Author reply to Wang et al.: “The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta‑analysis”11
Human Papillomavirus Type and Viral Load in Relation to Circulating Cell-Free Tumour HPV DNA Level and Survival in Cervical Cancer11
Extracellular Histones Profiles of Pediatric H3K27-Altered Diffuse Midline Glioma11
Inner Ear Gene Therapy: An Overview from Bench to Bedside11
Chimeric Genes Causing 11β-Hydroxylase Deficiency: Implications in Clinical and Molecular Diagnosis11
Fluorescence Imaging-Assessed Surgical Margin Detection in Head and Neck Oncology by Passive and Active Targeting11
Retroviral Remnants in the Human Genome: Classification, Integration and Regulation11
Blood Biomarkers of Long COVID: A Systematic Review11
Real-World Evidence of the Prevalence of Driver Mutations in Anorectal Melanoma10
Flavonoids in the Treatment of Non-small Cell Lung Cancer via Immunomodulation: Progress to Date10
Diagnostic Approaches to Investigate JAK2-Unmutated Erythrocytosis Based on a Single Tertiary Center Experience10
The Complement System and C4b-Binding Protein: A Focus on the Promise of C4BPα as a Biomarker to Predict Clopidogrel Resistance10
Papillary Thyroid Carcinoma: Correlation Between Molecular and Clinical Features10
Pre-analytical Best Practices for RNA Sequencing from Small Biopsies and Cytologic Specimens10
The Role of [18F]F-FDG PET/CT for Predicting Histology and Prognosis in Patients with Thymic Lesions10
Circulating Tumor DNA Profiling Reveals Genomic Evolution in Recurrent Gastric or Gastroesophageal Junction Cancer10
Comment on: “Personalized Medicine in Cystic Fibrosis: Characterization of Eight Rare CFTR Variants in Intestinal Organoids and Cellular Models”9
Author’s Reply to Yang and Wang: “Personalized Medicine in Cystic Fibrosis: Characterization of Eight Rare CFTR Variants in Intestinal Organoids and Cellular Models”9
Smart Nanomedicines for Neurodegenerative Diseases: Empowering New Therapies with Molecular Imaging and Artificial Intelligence9
Nanocarrier-Mediated Delivery of MicroRNAs for Fibrotic Diseases9
Effective Utilization of a Customized Targeted Hybrid Capture RNA Sequencing in the Routine Molecular Categorization of Adolescent and Adult B-Lineage Acute Lymphoblastic Leukemia: A Real-World Experi9
Exploring the Role of HtrA Family Genes in Cancer: A Systematic Review9
Zevorcabtagene Autoleucel: First Approval8
Characterization of 13 Novel Genetic Variants in Genes Associated with Epilepsy: Implications for Targeted Therapeutic Strategies8
Cardiovascular Aging: From Molecular Mechanisms to Targeted Therapies8
Tumour Marker Expression in Head and Neck Malignancies to Identify Potential Targets for Intraoperative Molecular Near-Infrared Imaging8
The Potential of Nanobodies for COVID-19 Diagnostics and Therapeutics8
Advances in RNA Viral Vector Technology to Reprogram Somatic Cells: The Paramyxovirus Wave8
Interlesional Heterogeneity of EGFR Mutations: A Systematic Review and Meta-analysis8
Functional Association of miR-133b and miR-21 Through Novel Gene Targets ATG5, LRP6 and SGPP1 in Coronary Artery Disease8
Long-Read Nanopore Sequencing of RPGR ORF15 is Enhanced Following DNase I Treatment of MinION Flow Cells7
‘Longing’ for the Next Generation of Liquid Biopsy: The Diagnostic Potential of Long Cell-Free DNA in Oncology and Prenatal Testing7
Optimization of a Quantitative PCR Methodology for Detection of Aspergillus spp. and Rhizopus arrhizus7
The Future of Chemogenetics for the Treatment of Spasticity7
Expanded Alternatives of CRISPR–Cas9 Applications in Immunotherapy of Colorectal Cancer7
Molecular Diagnosis of Primary Cardiomyopathy in 231 Unrelated Pediatric Cases by Panel-Based Next-Generation Sequencing: A Major Focus on Five Carriers of Biallelic TNNI3 Pathogenic Variants7
SARS-CoV-2 Testing Strategies in the Diagnosis and Management of COVID-19 Patients in Low-Income Countries: A Scoping Review7
Identification of Somatic Genetic Variants in Superficial Vascular Malformations by Liquid Biopsy in a Cohort of 88 Patients from a French Hospital7
Is There a Role for FAPI PET in Urological Cancers?6
Dengue Fever Diagnosis: Performance Characteristics of Current Tests and Emerging Detection Technologies6
The Future of CAR T Therapeutics to Treat Autoimmune Disorders6
Radioligand–Antibody Conjugates: Integrating Antibody Engineering, Chelator Chemistry, and Radioligands for Precision Theranosis6
Clonal Hematopoiesis from a Diagnostic Perspective: 10 Years of CHIP6
Clinical Utility of an RNA-based Gene Fusion Assay in Sarcoma for Diagnosis and Management: Experience in an Australian Laboratory6
Clinical Progresses and Challenges of Bispecific Antibodies for the Treatment of Solid Tumors6
Real-Time Detection of Colorectal Cancer Using Topical Application of a pH-Activatable Fluorophore6
Modern Biomarkers for Autism Spectrum Disorder: Future Directions6
Cell Therapy of Severe Ischemia in People with Diabetic Foot Ulcers—Do We Have Enough Evidence?6
A miRNA-Based Approach in Autosomal Dominant Polycystic Kidney Disease: Challenges and Insights from Adult to Pediatric Evidence6
Clostridium Bacteria: Harnessing Tumour Necrosis for Targeted Gene Delivery6
Targeting Cytotoxic T-Cell Effector Function with Granzyme B PET: Translational Advances Toward Predicting Immunotherapy Outcomes6
Tracking the Plasma C-Terminal Agrin Fragment as a Biomarker of Neuromuscular Decline in 18- to 87-Year-Old Men6
Clinical Validation of a Targeted RNA-Sequencing Assay for Driver Gene Alteration Detection in Non-Small Cell Lung Cancer5
Why are Some Tissues More Vulnerable? Revisiting Tissue Specificity in Hereditary Cancer Syndromes5
Single-Cell Sequencing in Neurodegenerative Disorders5
Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis5
Pitfalls in Cutaneous Melanoma Diagnosis and the Need for New Reliable Markers5
Multicenter Performance Evaluation of the Revogene® GBS DS Real-Time PCR Assay for Group B Streptococcus Detection During Labor5
Cell-Free DNA: Features and Attributes Shaping the Next Frontier in Liquid Biopsy5
Digital PCR-Based Method for Detecting CDKN2A Loss in Brain Tumours5
Gene Therapies in Clinical Development to Treat Retinal Disorders5
MicroRNA-146a Signature in Psoriasis: A Systematic Review and Meta-Analysis5
Zopapogene Imadenovec: First Approval5
Advancing Rabies Diagnosis: Time for a New “Gold Standard”?5
Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta-Analysis5
Exosomal Cargo-Derived Mediators of Ovarian Cancer Chemoresistance5
Development of a Novel Internally Controlled HrpB1 Gene-Based Real-Time qPCR Assay for Detection of Burkholderia pseudomallei4
Multicenter In-House Evaluation of an Amplicon-Based Next−Generation Sequencing Panel for Comprehensive Molecular Profiling4
Mycobacterium tuberculosis Detection Using CRISPR Technology: An Updated Systematic Review and Meta-analysis4
Beyond Binary FISH Results: Targeted NGS Provides Deeper Characterization of MYC and Broader Genomic Alterations in DLBCL4
Clinical Potential of Expanded Noninvasive Prenatal Testing for Detection of Aneuploidies and Microdeletion/Microduplication Syndromes4
The Metabolic Landscape of Breast Cancer and Its Therapeutic Implications4
Smelling the Disease: Diagnostic Potential of Breath Analysis4
From PIK3CA Mutations to Rational PI3K Inhibition for the Treatment of Colorectal Cancer4
Validation of a Transcriptome-Based Assay for Classifying Cancers of Unknown Primary Origin4
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