Molecular Diagnosis & Therapy

Papers
(The median citation count of Molecular Diagnosis & Therapy is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Predictive Ability of Serum Amino Acid Levels to Differentiate Fibromyalgia Patients from Healthy Subjects112
ADORA3: A Key Player in the Pathogenesis of Intracranial Aneurysms and a Potential Diagnostic Biomarker80
The Role of MicroRNAs in the Pathogenesis and as Biomarkers for Pediatric Epilepsy: A Systematic Review73
Comment on “Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta‑Analysis”59
Personalized Cancer Monitoring Assay for the Detection of ctDNA in Patients with Solid Tumors53
A Window of Opportunity for Newborn Screening48
Indirect Clinical Validation of a Programmed Death-Ligand 1 Laboratory-Developed Test for Gastric/Gastroesophageal Junction Adenocarcinoma with 22C3 Antibody Concentrate47
Gene Therapy for Cardiomyocyte Renewal: Cell Cycle, a Potential Therapeutic Target42
Personalized Medicine in Cystic Fibrosis: Characterization of Eight Rare CFTR Variants in Intestinal Organoids and Cellular Models39
Evaluation of Minimal Residual Disease in Patients with Neuroblastoma39
FAPI-Targeted Molecular Imaging: Transforming Insights into Post-Ischemic Myocardial Remodeling?32
Expression Signature of Immune-Related MicroRNAs in Autoimmune Skin Disease: Psoriasis and Vitiligo Insights31
Drug Hypersensitivity Reactions in Patients with Cystic Fibrosis: Potential Value of the Lymphocyte Toxicity Assay to Assess Risk31
Research Progress on Signal Conversion Based on Aptamer Combined CRISPR/Cas System in Biosensors29
Prediction of Biomarker Expression on Primary Pancreatic Ductal Adenocarcinoma Tissues Using Fine-Needle Biopsies: Paving the Way for a Patient-Tailored Molecular Imaging Approach27
Glioma 2021 WHO Classification: The Superiority of NGS Over IHC in Routine Diagnostics26
Afamitresgene Autoleucel: First Approval26
Personalizing Oncolytic Immunovirotherapy Approaches25
Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders25
Correction to: Revakinagene Taroretcel: First Approval25
Inflammatory Gene Panel Guiding the Study of Genetics in Inflammatory Bowel Disease22
Advances and Challenges in the Diagnosis of Leishmaniasis21
Fatty Acid Desaturase: The Yin or Yang of Disease Pathology20
Development of a New Rapid Simultaneous Molecular Assay for the Detection of STI Pathogens and Drug Resistance-Associated Mutations20
Clinical Metagenomic Next-Generation Sequencing for Diagnosis of Central Nervous System Infections: Advances and Challenges20
Transcript-Based Diagnosis and Expanded Phenotype of an Intronic Mutation in TPM3 Myopathy19
Comment on “The Diagnostic and Prognostic Value of miR‑155 in Cancers: An Updated Meta‑analysis”18
Diagnosis of Lung Cancer Through Exhaled Breath: A Comprehensive Study18
Long-Range PCR and Nanopore Sequencing Enables High-Throughput Detection of TCF4 Trinucleotide Repeat Expansions in Fuchs Endothelial Corneal Dystrophy18
MET-Targeted Therapies and Clinical Outcomes: A Systematic Literature Review17
Advances in Pompe Disease Treatment: From Enzyme Replacement to Gene Therapy17
Molecular Therapeutics in Development to Treat Alzheimer’s Disease17
Single Nucleotide Variants in KIF14 Gene May Have Prognostic Value in Breast Cancer16
Performance of a Rapid Digital PCR Test for the Detection of Non-Small Cell Lung Cancer (NSCLC) Variants16
Smart PROTACs Enable Controllable Protein Degradation for Precision Cancer Therapy16
Targeted Therapy in Salivary Gland Cancer: Prevalence of a Selected Panel of Actionable Molecular Alterations in a German Tertiary Referral Center Patient Cohort15
Achromatopsia: Genetics and Gene Therapy15
In vivo LNP-CRISPR Approaches for the Treatment of Hemophilia15
The Road Traveled and Journey Ahead for the Genetics and Genomics of Tinnitus15
Evolutionary Overview and Future Perspectives: ESR1 Mutations, Liquid Biopsy, and Artificial Intelligence for a New Era of Personalized Medicine in ER+ Breast Cancer15
Molecular Dynamics as a Precision Therapy: A Perspective on Epileptic Encephalopathies15
Correction to: Molecular Therapeutics in Development to Treat Alzheimer’s Disease14
Lifileucel: First Approval14
Role of lncRNAs in Remodeling of the Coronary Artery Plaques in Patients with Atherosclerosis14
Is the Homologous Recombination Repair Mutation Defined by a 15-Gene Panel Associated with the Prognosis of Epithelial Ovarian Cancer?14
The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta-analysis14
Selecting Targets for Molecular Imaging of Gastric Cancer: An Immunohistochemical Evaluation13
Correction: Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders13
Celomic Fluid: Laboratory Workflow for Prenatal Diagnosis of Monogenic Diseases13
Bridging the Gap: Cost-Effective Strategies for Detecting Ph-Like B-Lineage ALL in Resource-Limited Settings12
The Role οf Ion Channels in the Development and Progression of Prostate Cancer12
Cell-Free HPV-DNA in Screening, Diagnosis, Prognosis, and Treatment Response Monitoring of Cervical Cancer12
Human Papillomavirus Type and Viral Load in Relation to Circulating Cell-Free Tumour HPV DNA Level and Survival in Cervical Cancer11
Correction to: Optimization of a Quantitative PCR Methodology for Detection of Aspergillus spp. and Rhizopus arrhizus11
Comment on “Prognostic Value of Programmed Death Ligand-1 Expression in Solid Tumors Irrespective of Immunotherapy Exposure: A Systematic Review and Meta‑Analysis”11
Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of “Second Hit” in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma11
Fluorescence Imaging-Assessed Surgical Margin Detection in Head and Neck Oncology by Passive and Active Targeting11
Psoriasis: A Multidimensional Review of Onset, Progression, Treatment, and the Evolution of Disease Models11
Extracellular Histones Profiles of Pediatric H3K27-Altered Diffuse Midline Glioma11
Emerging RNAi Therapies to Treat Hypertension11
Correction to: Exploratory Prognostic Biomarkers of Complement-Mediated Thrombotic Microangiopathy (CM-TMA) in Adults with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of a Phase III Study of R11
Chimeric Genes Causing 11β-Hydroxylase Deficiency: Implications in Clinical and Molecular Diagnosis10
Author reply to Wang et al.: “The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta‑analysis”10
Exploratory Prognostic Biomarkers of Complement-Mediated Thrombotic Microangiopathy (CM-TMA) in Adults with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of a Phase III Study of Ravulizumab10
Inner Ear Gene Therapy: An Overview from Bench to Bedside10
EasyNAT MP Assay: A Simple, Rapid, and Low-Cost Method to Detect Mycoplasma pneumoniae Using Cross-Priming Amplification Technology10
Future Prospects for Epigenetics in Autism Spectrum Disorder10
Blood Biomarkers of Long COVID: A Systematic Review10
Papillary Thyroid Carcinoma: Correlation Between Molecular and Clinical Features10
Obecabtagene Autoleucel: First Approval10
Flavonoids in the Treatment of Non-small Cell Lung Cancer via Immunomodulation: Progress to Date9
Mutational Characteristics of Primary Mucosal Melanoma: A Systematic Review9
Diagnostic Approaches to Investigate JAK2-Unmutated Erythrocytosis Based on a Single Tertiary Center Experience9
Circulating Tumor DNA Profiling Reveals Genomic Evolution in Recurrent Gastric or Gastroesophageal Junction Cancer9
Cardiovascular Aging: From Molecular Mechanisms to Targeted Therapies8
Real-World Evidence of the Prevalence of Driver Mutations in Anorectal Melanoma8
Prognostic Value of Programmed Death Ligand-1 Expression in Solid Tumors Irrespective of Immunotherapy Exposure: A Systematic Review and Meta-Analysis8
Identification of Somatic Genetic Variants in Superficial Vascular Malformations by Liquid Biopsy in a Cohort of 88 Patients from a French Hospital8
Long-Read Nanopore Sequencing of RPGR ORF15 is Enhanced Following DNase I Treatment of MinION Flow Cells8
The Role of [18F]F-FDG PET/CT for Predicting Histology and Prognosis in Patients with Thymic Lesions8
Evaluation of the Suitability of RNAscope as a Technique to Measure Gene Expression in Clinical Diagnostics: A Systematic Review8
Exploring the Role of HtrA Family Genes in Cancer: A Systematic Review8
Evaluation of Factors that Affect the Performance of COVID-19 Molecular Assays Including Presence of Symptoms, Number of Detected Genes and RNA Extraction Type8
Effective Utilization of a Customized Targeted Hybrid Capture RNA Sequencing in the Routine Molecular Categorization of Adolescent and Adult B-Lineage Acute Lymphoblastic Leukemia: A Real-World Experi8
Smart Nanomedicines for Neurodegenerative Diseases: Empowering New Therapies with Molecular Imaging and Artificial Intelligence8
The Complement System and C4b-Binding Protein: A Focus on the Promise of C4BPα as a Biomarker to Predict Clopidogrel Resistance8
Nanocarrier-Mediated Delivery of MicroRNAs for Fibrotic Diseases8
Molecular Diagnosis of Primary Cardiomyopathy in 231 Unrelated Pediatric Cases by Panel-Based Next-Generation Sequencing: A Major Focus on Five Carriers of Biallelic TNNI3 Pathogenic Variants8
Optimization of a Quantitative PCR Methodology for Detection of Aspergillus spp. and Rhizopus arrhizus7
Zevorcabtagene Autoleucel: First Approval7
Advances in RNA Viral Vector Technology to Reprogram Somatic Cells: The Paramyxovirus Wave7
Characterization of 13 Novel Genetic Variants in Genes Associated with Epilepsy: Implications for Targeted Therapeutic Strategies7
The Potential of Nanobodies for COVID-19 Diagnostics and Therapeutics7
Tumour Marker Expression in Head and Neck Malignancies to Identify Potential Targets for Intraoperative Molecular Near-Infrared Imaging7
Functional Association of miR-133b and miR-21 Through Novel Gene Targets ATG5, LRP6 and SGPP1 in Coronary Artery Disease7
Clinical Progresses and Challenges of Bispecific Antibodies for the Treatment of Solid Tumors6
The Future of CAR T Therapeutics to Treat Autoimmune Disorders6
Expanded Alternatives of CRISPR–Cas9 Applications in Immunotherapy of Colorectal Cancer6
Clinical Utility of an RNA-based Gene Fusion Assay in Sarcoma for Diagnosis and Management: Experience in an Australian Laboratory6
‘Longing’ for the Next Generation of Liquid Biopsy: The Diagnostic Potential of Long Cell-Free DNA in Oncology and Prenatal Testing6
Clostridium Bacteria: Harnessing Tumour Necrosis for Targeted Gene Delivery6
The Future of Chemogenetics for the Treatment of Spasticity6
Is There a Role for FAPI PET in Urological Cancers?6
Cell Therapy of Severe Ischemia in People with Diabetic Foot Ulcers—Do We Have Enough Evidence?6
Advancing Rabies Diagnosis: Time for a New “Gold Standard”?6
SARS-CoV-2 Testing Strategies in the Diagnosis and Management of COVID-19 Patients in Low-Income Countries: A Scoping Review6
A miRNA-Based Approach in Autosomal Dominant Polycystic Kidney Disease: Challenges and Insights from Adult to Pediatric Evidence6
Clonal Hematopoiesis from a Diagnostic Perspective: 10 Years of CHIP5
Modern Biomarkers for Autism Spectrum Disorder: Future Directions5
Zopapogene Imadenovec: First Approval5
Single-Cell Sequencing in Neurodegenerative Disorders5
From PIK3CA Mutations to Rational PI3K Inhibition for the Treatment of Colorectal Cancer5
Tracking the Plasma C-Terminal Agrin Fragment as a Biomarker of Neuromuscular Decline in 18- to 87-Year-Old Men5
Clinical Validation of a Targeted RNA-Sequencing Assay for Driver Gene Alteration Detection in Non-Small Cell Lung Cancer5
Pitfalls in Cutaneous Melanoma Diagnosis and the Need for New Reliable Markers5
Multicenter Performance Evaluation of the Revogene® GBS DS Real-Time PCR Assay for Group B Streptococcus Detection During Labor5
Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta-Analysis5
Gestational Diabetes is Associated with an Increased Expression of miR-27a in Peripheral Blood Mononuclear Cells5
MicroRNA-146a Signature in Psoriasis: A Systematic Review and Meta-Analysis5
Cell-Free DNA: Features and Attributes Shaping the Next Frontier in Liquid Biopsy5
Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option5
Clinical Potential of Expanded Noninvasive Prenatal Testing for Detection of Aneuploidies and Microdeletion/Microduplication Syndromes5
Proclarix, A New Biomarker for the Diagnosis of Clinically Significant Prostate Cancer: A Systematic Review4
Immune Checkpoint Blockade Therapy for Breast Cancer: Lessons from Epithelial–Mesenchymal Transition4
Clinical Utility of Implementing a Frontline NGS-Based DNA and RNA Fusion Panel Test for Patients with Suspected Myeloid Malignancies4
Digital PCR-Based Method for Detecting CDKN2A Loss in Brain Tumours4
Mycobacterium tuberculosis Detection Using CRISPR Technology: An Updated Systematic Review and Meta-analysis4
Gene Therapies in Clinical Development to Treat Retinal Disorders4
Validation of a Transcriptome-Based Assay for Classifying Cancers of Unknown Primary Origin4
Diagnostic Potential of Cross-Specimen microRNA Panels as Biomarkers for Colorectal Cancer: A Systematic Review and Meta-analysis4
Multicenter In-House Evaluation of an Amplicon-Based Next−Generation Sequencing Panel for Comprehensive Molecular Profiling4
The Metabolic Landscape of Breast Cancer and Its Therapeutic Implications4
Smelling the Disease: Diagnostic Potential of Breath Analysis4
Development of a Novel Internally Controlled HrpB1 Gene-Based Real-Time qPCR Assay for Detection of Burkholderia pseudomallei4
Prevalence of NTRK Fusions in Canadian Solid Tumour Cancer Patients4
Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis4
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