OOIR: Observatory of International Research

Papers

(The TQCC of Experimental and Molecular Medicine is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
LINC00319 promotes cancer stem cell-like properties in laryngeal squamous cell carcinoma via E2F1-mediated upregulation of HMGB3	454
Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy	228
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability	225
Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations in mismatch repair genes in methotrexate-resistant HT-29 cells	190
BIX01294 inhibits EGFR signaling in EGFR-mutant lung adenocarcinoma cells through a BCKDHA-mediated reduction in the EGFR level	181
MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 interaction with Toll-like receptor-4	179
The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis	173
Calbindin regulates Kv4.1 trafficking and excitability in dentate granule cells via CaMKII-dependent phosphorylation	171
Exploiting the mechanism of estrogen-induced transcription to fight breast cancer	168
Novel KCNQ4 variants in different functional domains confer genotype- and mechanism-based therapeutics in patients with nonsyndromic hearing loss	153
Methods in organoids: a model that goes beyond our imagination	151
Plasma extracellular vesicle delivery of miR-210-3p by targeting ATG7 to promote sepsis-induced acute lung injury by regulating autophagy and activating inflammation	148
Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response	136
TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway	108
Hypothalamic primary cilium: A hub for metabolic homeostasis	91
Fibrinolytic nanocages dissolve clots in the tumor microenvironment, improving the distribution and therapeutic efficacy of anticancer drugs	89
Neuroendocrine control of appetite and metabolism	86
Slimy partners: the mucus barrier and gut microbiome in ulcerative colitis	73
Protein arginine methyltransferases: promising targets for cancer therapy	72
Type I and III interferon responses in SARS-CoV-2 infection	72
Roles of circadian clocks in cancer pathogenesis and treatment	71
Lipidome profile predictive of disease evolution and activity in rheumatoid arthritis	70
TRIM45 causes neuronal damage by aggravating microglia-mediated neuroinflammation upon cerebral ischemia and reperfusion injury	64
Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis	64
Aurora kinase A, a synthetic lethal target for precision cancer medicine	62

Hypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss	60
The impact of fine particulate matter (PM) on various beneficial functions of human endometrial stem cells through its key regulator SERPINB2	59
The p53-caspase-2 axis in the cell cycle and DNA damage response	57
Glutathione peroxidase-1 regulates ASK1-dependent apoptosis via interaction with TRAF2 in RIPK3-negative cancer cells	55
The clinical use of blood-test factors for Alzheimer’s disease: improving the prediction of cerebral amyloid deposition by the QPLEXTM Alz plus assay kit	55
MicroRNA-26a/b-5p promotes myocardial infarction-induced cell death by downregulating cytochrome c oxidase 5a	51
Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells	49
LncRNA HSPA7 in human atherosclerotic plaques sponges miR-223 and promotes the proinflammatory vascular smooth muscle cell transition	45
Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis	44
Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair	44
ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP1	43
Epigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia	42