OOIR: Observatory of International Research

Papers

(The median citation count of Korean Journal of Physiology & Pharmacology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Aspirin-induced acetylation of APE1/Ref-1 enhances RAGE binding and promotes apoptosis in ovarian cancer cells	32
Mad2B forms a complex with Cdc20, Cdc27, Rev3 and Rev1 in response to cisplatin-induced DNA damage	17
Low-frequency auricular vagus nerve stimulation facilitates cerebrospinal fluid influx by promoting vasomotion	14
Characterization of a conjugated polysuccinimide-carboplatin compound	13
Carbon monoxide activation of delayed rectifier potassium currents of human cardiac fibroblasts through diverse pathways	13
The NADPH oxidase inhibitor diphenyleneiodonium suppresses Ca²⁺ signaling and contraction in rat cardiac myocytes	11
Hyperbaric oxygenation applied before or after mild or hard stress: effects on the redox state in the muscle tissue	11
3,3′,4,4′-tetrachlorobiphenyl (PCB77) enhances human Kv1.3 channel currents and alters cytokine production	10
Neogambogic acid relieves myocardial injury induced by sepsis via p38 MAPK/NF-κB pathway	10
Role of TGF-β1/SMADs signalling pathway in resveratrol-induced reduction of extracellular matrix deposition by dexamethasone-treated human trabecular meshwork cells	10
Deletion of adipose triglyceride lipase abolishes blood flow increase after β3-adrenergic stimulation in visceral adipose tissue of mice	9
Corrigendum to: Pre-ischemic treatment with ampicillin reduces neuronal damage in the mouse hippocampus and neostriatum after transient forebrain ischemia	9
Wogonin attenuates vascular remodeling by inhibiting smooth muscle cell proliferation and migration in hypertensive rat	9
A simple and novel equation to estimate the degree of bleeding in haemorrhagic shock: mathematical derivation and preliminary in vivo validation	9
Carvacrol improves blood lipid and glucose in rats with type 2 diabetes mellitus by regulating short-chain fatty acids and the GPR41/43 pathway	9
Protective effects and mechanism of coenzyme Q10 and vitamin C on doxorubicin-induced gastric mucosal injury and effects of intestinal flora	9
Naringenin modulates GABA mediated response in a sexdependent manner in substantia gelatinosa neurons of trigeminal subnucleus caudalis in immature mice	9
HMGB1 increases RAGE expression in vascular smooth muscle cells via ERK and p-38 MAPK-dependent pathways	8
Microglial galectin-3 increases with aging in the mouse hippocampus	8
Unveiling the impact of lysosomal ion channels: balancing ion signaling and disease pathogenesis	8
Ca²⁺ entry through reverse Na+/Ca²⁺ exchanger in NCI-H716, glucagon-like peptide-1 secreting cells	8
Aurantio-obtusin exerts an anti-inflammatory effect on acute kidney injury by inhibiting NF-κB pathway	8
The impact of CYP2D6 on donepezil concentration and its lack of effect on the treatment response and adverse effect in Korean patients with Alzheimer's disease	7
Lactobacillus johnsonii JERA01 upregulates the production of Th1 cytokines and modulates dendritic cells-mediated immune response	7
Lyso-globotriaosylsphingosine induces endothelial dysfunction via autophagy-dependent regulation of necroptosis	7

Effects of sleep deprivation on coronary heart disease	7
Hemin attenuates bleomycin-induced lung fibrosis in mice by regulating the TGF-β1/MAPK and AMPK/SIRT1/PGC-1α/HO-1/NF-κB pathways	7
Monotropein resists atherosclerosis by reducing inflammation, oxidative stress, and abnormal proliferation and migration of vascular smooth muscle cells	7
MST1R as a potential new target antigen of chimeric antigen receptor T cells to treat solid tumors	7
Gaseous signal molecule SO₂ regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes	7
Transcriptional regulation of genetic variants in the SLC40A1 promoter	6
Specific kinesin and dynein molecules participate in the unconventional protein secretion of transmembrane proteins	6
Development and assessment of nano drug delivery systems for combined delivery of rosuvastatin and ezetimibe	6
Lithium and exercise ameliorate insulin-deficient hyperglycemia by independently attenuating pancreatic α-cell mass and hepatic gluconeogenesis	6
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling	6
GBA inhibition suppresses ovarian cancer growth, survival and receptor tyrosine kinase AXL-mediated signaling pathways	6
Functional interplay between non-canonical inflammasomes and autophagy in inflammatory responses and diseases	6
Construction and validation of a synthetic phage-displayed nanobody library	6
Biophysically stressed vascular smooth muscle cells express MCP-1 via a PDGFR-β-HMGB1 signaling pathway	6
Mechanism of Wenshen Xuanbi Decoction in the treatment of osteoarthritis based on network pharmacology and experimental verification	6
Neurosteroids and neurological disorders	6
Vinpocetine, a phosphodiesterase 1 inhibitor, mitigates atopic dermatitis-like skin inflammation	5
Roles of metabotropic glutamate receptor 5 in low [Mg²⁺]_o-induced interictal epileptiform activity in rat hippocampal slices	5
Docetaxel-loaded PLGA nanoparticles to increase pharmacological sensitivity in MDA-MB-231 and MCF-7 breast cancer cells	5
Requirement of β subunit for the reduced voltage-gated Na⁺ current of a Brugada syndrome patient having novel double missense mutation (p.A385T/R504T) of SCN5A	5
Association between metabolic syndrome components and cardiac autonomic modulation in southern Indian adults with pre-metabolic syndrome: hyperglycemia is the major contributing factor	5
Corrigendum to: Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion	5
Nicotinamide phosphoribosyltransferase regulates the cell differentiation and mineralization in cultured odontoblasts	5
Chios gum mastic enhance the proliferation and odontogenic differentiation of human dental pulp stem cells	5
Apoptin gene delivery by a PAMAM dendrimer modified with a nuclear localization signal peptide as a gene carrier for brain cancer therapy	5
Hydrogen sulfide restores cardioprotective effects of remote ischemic preconditioning in aged rats via HIF-1α/Nrf2 signaling pathway	4
Corrigendum to: Development and assessment of nano drug delivery systems for combined delivery of rosuvastatin and ezetimibe	4
Whole body hypoxic preconditioning-mediated multiorgan protection in db/db mice via nitric oxide-BDNF-GSK-3β-Nrf2 signaling pathway	4
Curcumin attenuates renal ischemia reperfusion injury via JNK pathway with the involvement of p300/CBP-mediated histone acetylation	4
Loss of RAR-α and RXR-α and enhanced caspase-3-dependent apoptosis in N-acetyl-p-aminophenol-induced liver injury in mice is tissue factor dependent	4
Antioxidation and anti-inflammatory effects of gamma-irradiated silk sericin and fibroin in H2O2-induced HaCaT Cell	4
Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway	4
Carnosol induces the osteogenic differentiation of bone marrow-derived mesenchymal stem cells via activating BMP-signaling pathway	4
Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner	4
Beneficial effects of naringenin and morin on interleukin-5 and reactive oxygen species production in BALB/c mice with ovalbumin-induced asthma	4
Lysophosphatidylcholine induces azurophil granule translocationviaRho/Rho kinase/F-actin polymerization in human neutrophils	3
Triptolide improves myocardial fibrosis in rats through inhibition of nuclear factor kappa B and NLR family pyrin domain containing 3 inflammasome pathway	3
Cornuside inhibits glucose-induced proliferation and inflammatory response of mesangial cells	3
Rosuvastatin activates autophagy via inhibition of the Akt/mTOR axis in vascular smooth muscle cells	3
Brain energy homeostasis: the evolution of the astrocyte-neuron lactate shuttle hypothesis	3
Store-operated calcium entry in the satellite glial cells of rat sympathetic ganglia	3
Melittin inhibits MPP⁺-induced HT22 cell death by suppressing Bax activation and improving mitochondrial function	3
Astragalus polysaccharide ameliorates diabetic retinopathy by inhibiting the SHH-Gli1-AQP1 signaling pathway in streptozotocin-induced type 2 diabetic rats	3
Inhibitory effects of the atypical antipsychotic, clozapine, on voltage-dependent K⁺ channels in rabbit coronary arterial smooth muscle cells	3
Decrease of glycogen synthase kinase 3β phosphorylation in the rat nucleus accumbens shell is necessary for amphetamineinduced conditioned locomotor activity	3
Cardioprotection via mitochondrial transplantation supports fatty acid metabolism in ischemia-reperfusion injured rat heart	3
Gallic acid-mitochondria targeting sequence-H₃R₉ induces mitochondria-targeted cytoprotection	3
Differential expression of ORAI channels and STIM proteins in renal cell carcinoma subtypes: implications for metastasis and therapeutic targeting	3
Atypical antipsychotic drug olanzapine inhibits 5-HT₃ receptor-mediated currents by allosteric and non-competitive mechanisms	2
MicroRNA-21 promotes epithelial-mesenchymal transition and migration of human bronchial epithelial cells by targeting poly (ADP-ribose) polymerase-1 and activating PI3K/AKT signaling	2

Cell-cell contacts via N-cadherin induce a regulatory renin secretory phenotype in As4.1 cells	2
The changes of nociception and the signal molecules expression in the dorsal root ganglia and the spinal cord after cold water swimming stress in mice	2
The role of discoid domain receptor 1 on renal tubular epithelial pyroptosis in diabetic nephropathy	2
Oxytocin-induced endothelial nitric oxide dependent vasorelaxation and ERK1/2-mediated vasoconstriction in the rat aorta	2
Effects of gas signaling molecule SO₂ in cardiac functions of hyperthyroid rats	2
Circ-SNX27 sponging miR-375/RPN1 axis contributes to hepatocellular carcinoma progression	2
Age-dependent expression of ion channel genes in rat	2
Carbon monoxide activates large-conductance calcium-activated potassium channels of human cardiac fibroblasts through various mechanisms	2
Dexmedetomidine alleviates blood-brain barrier disruption in rats after cerebral ischemia-reperfusion by suppressing JNK and p38 MAPK signaling	2
Kidney protective potential of lactoferrin: pharmacological insights and therapeutic advances	2
Protective effects of lutein against vancomycin-induced acute renal injury in mice via upregulation of peroxisome proliferator-activated receptor gamma/nuclear factor erythroid 2-related factor 2 and	2
Hydrogen sulfide, a gaseous signaling molecule, elongates primary cilia on kidney tubular epithelial cells by activating extracellular signal-regulated kinase	2
ACY-241, a histone deacetylase 6 inhibitor, suppresses the epithelial–mesenchymal transition in lung cancer cells by downregulating hypoxia-inducible factor-1 alpha	2
Effects of rosiglitazone, an antidiabetic drug, on Kv3.1 channels	2
Precision proteomics with TurboID: mapping the suborganelle landscape	2
Quetiapine competitively inhibits 5-HT₃ receptor-mediated currents in NCB20 neuroblastoma cells	1
Flos magnoliae constituent fargesin has an anti-allergic effect via ORAI1 channel inhibition	1
New in vitro multiple cardiac ion channel screening system for preclinical Torsades de Pointes risk prediction under the Comprehensive in vitro Proarrhythmia Assay concepta	1
Saturated fatty acid-inducible miR-103-3p impairs the myogenic differentiation of progenitor cells by enhancing cell proliferation through Twinfilin-1/F-actin/YAP1 axis	1
Carbon monoxide releasing molecule-2 suppresses stretch-activated atrial natriuretic peptide secretion by activating large-conductance calcium-activated potassium channels	1
The physiological and pharmacological roles of prostaglandins in hair growth	1
Depilatory creams increase the number of hair follicles, and dermal fibroblasts expressing interleukin-6, tumor necrosis factor-α, and tumor necrosis factor-β in mouse skin	1
Relation between heart rate variability and spectral analysis of electroencephalogram in chronic neuropathic pain patients	1
Anti-inflammatory effects of LCB 03-0110 on human corneal epithelial and murine T helper 17 cells	1
Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3′3-diindolylmethane suppresses esophageal cancer tumorigenesis	1
Corrigendum to: Cardioprotection via mitochondrial transplantation supports fatty acid metabolism in ischemia-reperfusion injured rat heart	1
RNA polymerase I subunit D activated by Yin Yang 1 transcription promote cell proliferation and angiogenesis of colorectal cancer cells	1
Wogonin inhibits radiation-induced DNA damage repair in hepatocellular carcinoma cells by upregulating p21	1
Glycine induces enhancement of bactericidal activity of neutrophils	1
Exosome-mediated lnc-ABCA12-3 promotes proliferation and glycolysis but inhibits apoptosis by regulating the toll-like receptor 4/nuclear factor kappa-B signaling pathway in esophageal squamous cell c	1
Combination of canagliflozin and puerarin alleviates the lipotoxicity to diabetic kidney in mice	1
Peptides derived from high voltage-gated calcium channel β subunit reduce blood pressure in rats	1
Multiple consecutive-biphasic pulse stimulation improves spatially localized firing of retinal ganglion cells in the degenerate retina	1
Sweroside plays a role in mitigating high glucose-induced damage in human renal tubular epithelial HK-2 cells by regulating the SIRT1/NF-κB signaling pathway	1
Roles of non-coding RNAs in intercellular crosstalk in cardiovascular diseases	1
Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated via TLR4/NF-κB pathway	1
Metformin alleviates chronic obstructive pulmonary disease and cigarette smoke extract-induced glucocorticoid resistance by activating the nuclear factor E2-related factor 2/heme oxygenase-1 signaling	1
Protective effect of 6′-Sialyllactose on LPS-induced macrophage inflammation via regulating Nrf2-mediated oxidative stress and inflammatory signaling pathways	1
Dendritic cells resist to disulfiram-induced cytotoxicity, but reduced interleukin-12/23(p40) production	1
Fine particulate matter induces osteoclast-mediated bone loss in mice	1
Echinochrome A inhibits HMGB1-induced vascular smooth muscle cell migration by suppressing osteopontin expression	1
Kir4.1 is coexpressed with stemness markers in activated astrocytes in the injured brain and a Kir4.1 inhibitor BaCl₂ negatively regulates neurosphere formation in culture	1
Mangiferin ameliorates cardiac fibrosis in D-galactose-induced aging rats by inhibiting TGF-β/p38/MK2 signaling pathway	1
Protective effect of low-intensity treadmill exercise against acetylcholine-calcium chloride-induced atrial fibrillation in mice	1
Rac1 inhibition protects the kidney against kidney ischemia/reperfusion through the inhibition of macrophage migration	1
Chemosensitizing effect and mechanism of imperatorin on the anti-tumor activity of doxorubicin in tumor cells and transplantation tumor model	1
Hydrogen sulfide ameliorates abdominal aorta coarctation-induced myocardial fibrosis by inhibiting pyroptosis through regulating eukaryotic translation initiation factor 2α phosphorylation and activat	1
Myricetin prevents sleep deprivation-induced cognitive impairment and neuroinflammation in rat brain via regulation of brain-derived neurotropic factor	1
Hyaluronan-mediated motility receptor-mediated aerobic glycolysis enhances stem-like properties and chemoresistance in lung adenocarcinoma	1
Novel artesunate-metformin conjugate inhibits bladder cancer cell growth associated with Clusterin/SREBP1/FASN signaling pathway	1
SKF96365 impedes spinal glutamatergic transmission-mediated neuropathic allodynia	1
Kinesin superfamily member 15 knockdown inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma	1
Inhibition of Wnt/β-catenin signaling by monensin in cervical cancer	1