OOIR: Observatory of International Research

Papers

(The TQCC of Korean Journal of Physiology & Pharmacology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Lithium and exercise ameliorate insulin-deficient hyperglycemia by independently attenuating pancreatic α-cell mass and hepatic gluconeogenesis	18
Development and assessment of nano drug delivery systems for combined delivery of rosuvastatin and ezetimibe	17
Effects of gas signaling molecule SO₂ in cardiac functions of hyperthyroid rats	16
Cardioprotection via mitochondrial transplantation supports fatty acid metabolism in ischemia-reperfusion injured rat heart	15
Phytochemicals as promising agents in Axl-targeted cancer treatment	15
Effects of in vivo treatment with K_v7.4 activator, URO-K10, on the impaired relaxation of pulmonary arteries in the monocrotaline-induced pulmonary hypertensive rats	14
Hydrogen sulfide, a gaseous signaling molecule, elongates primary cilia on kidney tubular epithelial cells by activating extracellular signal-regulated kinase	14
Differential expression of ORAI channels and STIM proteins in renal cell carcinoma subtypes: implications for metastasis and therapeutic targeting	14
Chios gum mastic enhance the proliferation and odontogenic differentiation of human dental pulp stem cells	14
Cell-cell contacts via N-cadherin induce a regulatory renin secretory phenotype in As4.1 cells	13
Protective effect of 6′-Sialyllactose on LPS-induced macrophage inflammation via regulating Nrf2-mediated oxidative stress and inflammatory signaling pathways	12
Chelidonine inhibits melanoma cell malignancy by inactivating TLR4/NF-κB and PI3K/AKT signaling pathways	12
Relation between heart rate variability and spectral analysis of electroencephalogram in chronic neuropathic pain patients	12
Hyaluronan-mediated motility receptor-mediated aerobic glycolysis enhances stem-like properties and chemoresistance in lung adenocarcinoma	12
Combination of canagliflozin and puerarin alleviates the lipotoxicity to diabetic kidney in mice	12
Group 1 metabotropic glutamate receptor 5 is involved in synaptically-induced Ca²⁺-spikes and cell death in cultured rat hippocampal neurons	11
Multiple consecutive-biphasic pulse stimulation improves spatially localized firing of retinal ganglion cells in the degenerate retina	11
Rac1 inhibition protects the kidney against kidney ischemia/reperfusion through the inhibition of macrophage migration	11
Sweroside plays a role in mitigating high glucose-induced damage in human renal tubular epithelial HK-2 cells by regulating the SIRT1/NF-κB signaling pathway	10
Ferroptosis and its role in gastric and colorectal cancers	10
Circular RNA circAtxn10 regulates skeletal muscle cell differentiation by targeting miR-143-3p and Chrna1	10
Anti-inflammatory effects of DA-9601, an extract of Artemisia asiatica, on aceclofenac-induced acute enteritis	10
Corrigendum to: Cornuside inhibits glucose-induced proliferation and inflammatory response of mesangial cells	9
Amorfrutin A ameliorates cerebral ischemia/reperfsion injury in vivo and in vitro via modulating Nrf2/HO-1 signaling pathway	9
Antitumor effects of valdecoxib on hypopharyngeal squamous carcinoma cells	9

Emerging role of circular RNAs in diabetic retinopathy	9
Chemopreventive potential of goniothalamin in diethylnitrosamine-induced hepatocellular carcinoma through the suppression of P13K/AKT signalling pathway	9
Effects of exercise on AKT/PGC1-α/FOXO3a pathway and muscle atrophy in cisplatin-administered rat skeletal muscle	8
Involvement of adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 in diallyl trisulfide-induced cytotoxicity in hepatocellular carcinoma cells	8
Edaravone alleviates lung damage in mice with hypoxic pulmonary hypertension by increasing nitric oxide synthase 3 expression	8
Thermotherapy as an alternative to exercise for metabolic health in obese postmenopausal women: focus on circulating irisin level	8
OAC1 improves mitofusin 2 expression to alleviate neuronal injury following experimental ischemic stroke	7
Profiling of endogenous metabolites and changes in intestinal microbiota distribution after GEN-001 (Lactococcus lactis) administration	7
Evaluation of the effects of disulfiram, an alcohol-aversive agent with anti-cancer activity, on mouse bone marrow cells	7
Microglial galectin-3 increases with aging in the mouse hippocampus	7
The transformative impact of large language models on medical writing and publishing: current applications, challenges and future directions	7
The WNT/Ca²⁺ pathway promotes atrial natriuretic peptide secretion by activating protein kinase C/transforming growth factor-β activated kinase 1/activating transcription factor 2 signaling	7
Differential expression of the enzymes regulating myosin light chain phosphorylation are responsible for the slower relaxation of pulmonary artery than mesenteric artery in rats	7
The impact of CYP2D6 on donepezil concentration and its lack of effect on the treatment response and adverse effect in Korean patients with Alzheimer's disease	7
Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ	7
Anti-cancer effects of fenbendazole on 5-fluorouracil-resistant colorectal cancer cells	7
Arctigenin induces caspase-dependent apoptosis in FaDu human pharyngeal carcinoma cells	7
Somatodendritic organization of pacemaker activity in midbrain dopamine neurons	7
Hemin attenuates bleomycin-induced lung fibrosis in mice by regulating the TGF-β1/MAPK and AMPK/SIRT1/PGC-1α/HO-1/NF-κB pathways	6
Unveiling the impact of lysosomal ion channels: balancing ion signaling and disease pathogenesis	6
Astragalus polysaccharide ameliorates diabetic retinopathy by inhibiting the SHH-Gli1-AQP1 signaling pathway in streptozotocin-induced type 2 diabetic rats	6
Hyperbaric oxygenation applied before or after mild or hard stress: effects on the redox state in the muscle tissue	6
Gaseous signal molecule SO₂ regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes	6
Roles of metabotropic glutamate receptor 5 in low [Mg²⁺]_o-induced interictal epileptiform activity in rat hippocampal slices	6
Ca²⁺ entry through reverse Na+/Ca²⁺ exchanger in NCI-H716, glucagon-like peptide-1 secreting cells	6
Beneficial effects of naringenin and morin on interleukin-5 and reactive oxygen species production in BALB/c mice with ovalbumin-induced asthma	6
Decrease of glycogen synthase kinase 3β phosphorylation in the rat nucleus accumbens shell is necessary for amphetamineinduced conditioned locomotor activity	6
Vericiguat reduces pyroptosis in rats with coronary microembolization by inhibiting the AMPK/Nrf2/NLRP3 signaling pathway	5
RNA polymerase I subunit D activated by Yin Yang 1 transcription promote cell proliferation and angiogenesis of colorectal cancer cells	5
New in vitro multiple cardiac ion channel screening system for preclinical Torsades de Pointes risk prediction under the Comprehensive in vitro Proarrhythmia Assay concepta	5
Tricyclic antidepressants dose-dependently modulate the biphasic activity of the TRPC5 channel through opioid receptors	5
Novel artesunate-metformin conjugate inhibits bladder cancer cell growth associated with Clusterin/SREBP1/FASN signaling pathway	5
Identification of telomere-related diagnostic markers in osteoarthritis based on bioinformatics analysis and machine learning	5
Organoid-based modeling and regenerative strategies for salivary gland dysfunction	5
Age-dependent expression of ion channel genes in rat	5
Circ-SNX27 sponging miR-375/RPN1 axis contributes to hepatocellular carcinoma progression	5
Paeonol accelerates skin wound healing by regulating macrophage polarization and inflammation in diabetic rats	5