OOIR: Observatory of International Research

Papers

(The TQCC of Biotechnology and Bioprocess Engineering is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Antioxidant and Probiotic Properties of Lactobacilli and Bifidobacteria of Human Origins	62
Artificial Intelligence in Drug Discovery: A Comprehensive Review of Data-driven and Machine Learning Approaches	47
Albumin: An Emerging Opportunity in Drug Delivery	39
Efficient Immobilization of Enzymes on Amino Functionalized MIL-125-NH2 Metal Organic Framework	32
Fabrication of Non-enzymatic Electrochemical Glucose Sensor Based on Nano-copper Oxide Micro Hollow-spheres	30
Recent Advances in Re-engineering Modular PKS and NRPS Assembly Lines	28
A Novel Strategy for the Microbial Removal of Heavy Metals: Cell-surface Display of Peptides	28
Antioxidant and Antibacterial Profiling of Pomegranate-pericarp Extract Functionalized-zinc Oxide Nanocomposite	27
Urolithin A Induces Brown-like Phenotype in 3T3-L1 White Adipocytes via β3-adrenergic Receptor-p38 MAPK Signaling Pathway	23
Suppressive Activities of Fisetin on Particulate Matter-induced Oxidative Stress	23
Exosome-mediated Let7c-5p Delivery for Breast Cancer Therapeutic Development	22
Hyaluronic Acid-based Biomimetic Hydrogels for Tissue Engineering and Medical Applications	21
Inhibitory Activities of Ononin on Particulate Matter-induced Oxidative Stress	20
Biotechnological Advances and Trends in Engineering Trichoderma reesei towards Cellulase Hyperproducer	20
Recent Advances in Systems Metabolic Engineering Strategies for the Production of Biopolymers	20
Plant Platforms for Efficient Heterologous Protein Production	20
Aptamer-immobilized Gold Nanoparticles Enable Facile and On-site Detection of Staphylococcus aureus	19
Alginate-chitosan Hydrogel Patch with Beta-glucan Nanoemulsion for Antibacterial Applications	19
CHO Cell Line Development and Engineering via Site-specific Integration: Challenges and Opportunities	19
Bioconversion of Plant Hydrolysate Biomass into Biofuels Using an Engineered Bacillus subtilis and Escherichia coli Mixed-whole Cell Biotransformation	19
Enhanced Fatty Acid Productivity by Parachlorella sp., a Freshwater Microalga, via Adaptive Laboratory Evolution Under Salt Stress	18
Production of TiO2-deposited Diatoms and Their Applications for Photo-catalytic Degradation of Aqueous Pollutants	16
Au Nanoparticle-decorated Nanoporous PEDOT Modified Glassy Carbon Electrode: A New Electrochemical Sensing Platform for the Detection of Glutathione	16
Medium Compositions for the Improvement of Productivity in Syngas Fermentation with Clostridium autoethanogenum	16
The Age of Multistimuli-responsive Nanogels: The Finest Evolved Nano Delivery System in Biomedical Sciences	16

Novel Herbal Medicine C-KOK Suppresses the Inflammatory Gene iNOS via the Inhibition of p-STAT-1 and NF-κB	16
A Versatile Surface Modification Method via Vapor-phase Deposited Functional Polymer Films for Biomedical Device Applications	15
Self-assembled Viral Nanoparticles as Targeted Anticancer Vehicles	15
Anticancer Activity of the Potential Pyropia yezoensis Galactan Fractionated in Human Prostate Cancer Cells	15
Recent Advances in Microbial Cell Growth Regulation Strategies for Metabolic Engineering	15
Hydroxyapatite Derived from Marine Resources and their Potential Biomedical Applications	14
Recent Advances in Synthetic Biology for the Engineering of Lactic Acid Bacteria	14
Genetic Biocontainment Systems for the Safe Use of Engineered Microorganisms	14
Metal-polyphenol Complexes as Versatile Building Blocks for Functional Biomaterials	14
The Role of Andrographolide on Skin Inflammations and Modulation of Skin Barrier Functions in Human Keratinocyte	13
Recent Progress in Microalgal Squalene Production and Its Cosmetic Application	13
Development of Origanum vulgare Cell Suspension Culture to Produce Polyphenols and the Stimulation Effect of Salicylic Acid Elicitation and Phenylalanine Feeding	13
Assessment of Computational Modeling of Fc-Fc Receptor Binding Through Protein-protein Docking Tool	12
Loss of ADAMTS15 Promotes Browning in 3T3-L1 White Adipocytes via Activation of β3-adrenergic Receptor	12
Efficient, Simple Production of Corresponding Alcohols from Supplemented C2-C8 Carboxylic Acids in Escherichia coli Using Acyl-CoA Transferase from Megasphaera hexanoica	12
Crosslinker-free Bovine Serum Albumin-loaded Chitosan/alginate Nanocomplex for pH-responsive Bursting Release of Oral-administered Protein	12
Affinity Peptide-based Electrochemical Biosensor for the Highly Sensitive Detection of Bovine Rotavirus	12
Identification of a Lung Cancer Biomarker Using a Cancer Cell Line and Screening of Olfactory Receptors for Biomarker Detection	12
Metabolic Engineering and Synthetic Biology of Cyanobacteria for Carbon Capture and Utilization	12
Applications of Natural and Synthetic Melanins as Biosorbents and Adhesive Coatings	12
Current Status of Pseudomonas putida Engineering for Lignin Valorization	11
Toxicity Evaluation of Household Detergents and Surfactants Using Zebrafish	11
An Enhancement of Antibacterial Activity and Synergistic Effect of Biosynthesized Silver Nanoparticles by Eurotium cristatum with Various Antibiotics	11
Development of a Cell-recycled Continuous Fermentation Process for Enhanced Production of Succinic Acid by High-yielding Mutants of Actinobacillus succinogenes	11
SARS-CoV-2 Variants: Mutations and Effective Changes	11
Co-evolving with Nature: The Recent Trends on the Mussel-inspired Polymers in Medical Adhesion	11
Exosome-modified PLGA Microspheres for Improved Internalization into Dendritic Cells and Macrophages	11
Improving the Microbial Production of Amino Acids: From Conventional Approaches to Recent Trends	11
Advanced Whole-cell Conversion for D-allulose Production Using an Engineered Corynebacterium glutamicum	11
Formulation of Glycyrrhizic Acid-based Nanocomplexes for Enhanced Anti-cancer and Anti-inflammatory Effects of Curcumin	10
Bioactive Peptides and Its Alternative Processes: A Review	10
Engineering Bacillus subtilis Cells as Factories: Enzyme Secretion and Value-added Chemical Production	10
Anti-obesity Potential of Lactobacillus spp. Isolated from Infant Feces	10
Carboxylesterase3 (Ces3) Interacts with Bone Morphogenetic Protein 11 and Promotes Differentiation of Osteoblasts via Smad1/5/9 Pathway	10
Tacrolimus Induces Apoptosis in Leukemia Jurkat Cells through Inactivation of the Reactive Oxygen Species-dependent Phosphoinositide-3-Kinase/Akt Signaling Pathway	10
Cilostazol Induces Apoptosis and Inhibits Proliferation of Hepatocellular Carcinoma Cells by Activating AMPK	10
Renal Protective Effects of Sparstolonin B in a Mouse Model of Sepsis	9
L-Dihydroxyphenylalanine (L-Dopa) Induces Brown-like Phenotype in 3T3-L1 White Adipocytes via Activation of Dopaminergic and β3-adrenergic Receptors	9
Hydrophobic Fractions of Triticum aestivum L. Extracts Contain Polyphenols and Alleviate Inflammation by Regulating Nuclear Factor-kappa B	9
Phenylboronic Acid-conjugated Exosomes for Enhanced Anticancer Therapeutic Effect by Increasing Doxorubicin Loading Efficiency	9
Antimicrobial Peptides Encounter Resistance of Aureolysin during Their Action on Staphylococcus aureus Biofilm	9
The Inhibitory Functions of Sparstolonin B against Ambient Fine Particulate Matter Induced Lung Injury	9
Study of the Extraction Kinetics and Calculation of Effective Diffusivity and Mass Transfer Coefficient in Negative Pressure Cavitation Extraction of Paclitaxel from Taxus chinensis	9
Engineering of Escherichia coli for the Economic Production L-phenylalanine in Large-scale Bioreactor	9
An Overview on Taxol Production Technology and Its Applications as Anticancer Agent	9
An Overview on Wound Dressings and Sutures Fabricated by Electrospinning	9
Progress in Preparation of Cellulase from Lignocellulose Using Fungi	9
Protection of Oxidative Stress-induced DNA Damage and Apoptosis by Rosmarinic Acid in Murine Myoblast C2C12 Cells	9
Nanostructure Materials: Efficient Strategies for Circulating Tumor Cells Capture, Release, and Detection	8
Functional Microbial Pigments Isolated from Chryseobacterium and Deinococcus species for Bio-paint Application	8

Genome-scale Modeling of Metabolism and Macromolecular Expression and Their Applications	8
Anti-inflammatory Effects of Scrophularia buergeriana Extract Mixture Fermented with Lactic Acid Bacteria	8
Effect of Organic Nitrogen Supplements on Syngas Fermentation Using Clostridium autoethanogenum	8
Hepatic Protective Effects of Jujuboside B through the Modulation of Inflammatory Pathways	8
Evaluation of Mechanical and Thermal Properties of Hydroxyapatite-levan Composite Bone Graft	8
Virus-like Particles as Antiviral Vaccine: Mechanism, Design, and Application	8
High-level Expression of an Acidic and Thermostable Chitosanase in Pichia pastoris Using Multi-copy Expression Strains and High-cell-density Cultivation	7
Recent Advances in the Utilization of Brown Macroalgae as Feedstock for Microbial Biorefinery	7
Washing-free Electrochemical Strategy to Detect Target DNA Utilizing Peroxidase Mimicking DNAzyme	7
Characterization of a Novel Acetogen Clostridium sp. JS66 for Production of Acids and Alcohols: Focusing on Hexanoic Acid Production from Syngas	7
Theabrownin in Black Tea Suppresses UVB-induced Matrix Metalloproteinase-1 Expression in HaCaT Keratinocytes	7
Mass Transfer and Rheological Characteristics in a Stirred Tank Bioreactor for Cultivation of Escherichia coli BL21	7
Natural/Synthetic Polymer Materials for Bioink Development	7
Immobilization of Candida rugosa Lipase on Magnetic Biosilica Particles: Hydrolysis and Transesterification Studies	7
Bioactive Porous Biocomposites Coated Magnesium Alloy Implant for Bone Rejuvenation Using a Fracture in Rat Model	7
Enhanced Enzymatic Saccharification of Wheat Flour Arabinoxylan and Barley Straw Using Recombinant Hemicellulases	7
Whole Cell Biotransformation of 1-dodecanol by Escherichia coli by Soluble Expression of ADH Enzyme from Yarrowia lipolytica	7
Osteostimulating Ability of β-tricalcium Phosphate/collagen Composite as a Practical Bone-grafting Substitute: In vitro and in vivo Comparison Study with Commercial One	7
Rapid and Complete Biodegradation of Acrylic Acid by a Novel Strain Rhodococcus ruber JJ-3: Kinetics, Carbon Balance, and Degradation Pathways	7
Efficient Surface Display of L-glutamate Oxidase and L-amino Acid Oxidase on Pichia pastoris Using Multi-copy Expression Strains	7
Nanoemulsion as an Effective Inhibitor of Biofilm-forming Bacterial Associated Drug Resistance: An Insight into COVID Based Nosocomial Infections	7
Regulatory Effect on Skin Differentiation by Mevastatin in Psoriasis Model Using TNF-α and IL-17 Induced HaCaT Cells	7
Biotransformation of Ginsenoside Rb1 to Ginsenoside F2 by Recombinant β-glucosidase from Rat Intestinal Enterococcus gallinarum	7
Optimally Fabricated Chitosan Particles Containing Ovalbumin Induced Cellular and Humoral Immunity in Immunized Mice	7
Production of Polyhydroxyalkanoates with the Fermentation of Methylorubrum extorquens Using Formate as a Carbon Substrate	6
Efficient Production of Various Minor Ginsenosides from PPD- and PPT-type Major Ginsenosides Using a Single Recombinant BglFc Isolated from Flavobacterium chilense	6
The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology	6
Electricity Effectively Utilization by Integrating Microbial Fuel Cells with Microbial Immobilization Technology for Denitrification	6
Antibacterial Activity of Prenylated Flavonoids Isolated from Hop against Fish Pathogens Streptococcus iniae and Vibrio vulnificus	6
New Bacterial Surface Display System Development and Application Based on Bacillus subtilis YuaB Biofilm Component as an Anchoring Motif	6
Optimized Sugar Extraction and Bioethanol Production from Lipid-extracted Sewage Sludge	6
Elucidation of the Mechanism and Kinetics of Ultrasonic Extraction of Paclitaxel from Plant Cell Cultures of Taxus chinensis	6
The Reductive Amination of Carbonyl Compounds Using Native Amine Dehydrogenase from Laribacter hongkongensis	6
Kinetic and Thermodynamic Study of the Ultrasonic Acetone-pentane Fractional Precipitation of Paclitaxel from the Plant Cell Cultures of Taxus chinensis	6
Substrate-binding Site Engineering of Candida antarctica Lipase B to Improve Selectivity for Synthesis of 1-monoacyl-sn-glycerols	6
An Overview on Methanotrophs and the Role of Methylosinus trichosporium OB3b for Biotechnological Applications	6
Selective Recovery of L-pipecolic Acid from L-lysine Bioconversion Mixture by Liquid-liquid Extraction	6
Directed Molecular Engineering of Mig6 Peptide Selectivity between Proto-oncogene ErbB Family Receptor Tyrosine Kinases	6
Kinetic Model for Simultaneous Saccharification and Fermentation of Brewers’ Spent Grain Liquor Using Lactobacillus delbrueckii Subsp. lactis	6
Hyperosmotic Adaptation of Pseudomonas protegens SN15-2 Helps Cells to Survive at Lethal Temperatures	6
Tremella fuciformis TFCUV5 Mycelial Culture-derived Exopolysaccharide Production and Its Anti-aging Effects on Skin Cells	6
Production of Functional Peptide with Anti-obesity Effect from Defatted Tenebrio molitor Larvae Using Proteolytic Enzyme	6
Development of Therapeutic Antibodies and Modulating the Characteristics of Therapeutic Antibodies to Maximize the Therapeutic Efficacy	6
Enhanced Production of 1-Deoxynojirimycin in Bacillus subtilis subsp. inaquosorum by Random Mutagenesis and Culture Optimization	6
Biocatalytic Production and Purification of the High-value Biochemical Paraxanthine	6
Microfluidic Single-cell Trapping and Cultivation for the Analysis of Host-viral Interactions	6
Filbertone Protects Obesity-induced Hypothalamic Inflammation by Reduction of Microglia-mediated Inflammatory Responses	6
Evaluating the Engineered Saccharomyces cerevisiae With High Spermidine Contents for Increased Tolerance to Lactic, Succinic, and Malic Acids and Increased Xylose Fermentation	6
Terminalia chebula Medicinal Uses: A Review of in vitro and in vivo Studies	6