Journal of Ginseng Research

Article	Citations
Ginsenoside Rb1 attenuates coronary microvascular inflammatory injury via NDUFS4-SIRT5-DUSP1-mediated mitochondrial quality control in a murine ischemia-reperfusion model	106
Ginsenoside Rh2 alleviates inflammatory response and enhances motor function recovery in spinal cord injury mice via the ROS/MAPK14 signaling pathway	92
Korean Red Ginseng water extract inhibits cadmium-induced lung injury via suppressing MAPK/ERK1/2/AP-1 pathway	81
Panax ginseng and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects	78
The necrotroph Botrytis cinerea promotes disease development in Panax ginseng by manipulating plant defense signals and antifungal metabolites degradation	76
The antitumor effects and apoptotic mechanism of 20(S)-Protopanaxadiol in acute myeloid leukemia	67
Ginsenoside Rh2 reduces m6A RNA methylation in cancer via the KIF26B-SRF positive feedback loop	65
Ginsenoside Rg5, a potent agonist of Nrf2, inhibits HSV-1 infection-induced neuroinflammation by inhibiting oxidative stress and NF-κB activation	64
Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1	62
Corrigendum to “Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitro and in vivo models” [J Ginseng Res 46 (2022) 426-434]	59
Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathways	59
Anti-thrombotic effects of ginsenoside Rk3 by regulating cAMP and PI3K/MAPK pathway on human platelets	55
Ginsenoside Rg1 suppresses cancer cell proliferation through perturbing mitotic progression	55
Panaxcerol D from Panax ginseng ameliorates the memory impairment induced by cholinergic blockade or Aβ25–35 peptide in mice	47
Ginsenoside F2 Restrains Hepatic Steatosis and Inflammation by Altering the Binding Affinity of Liver X Receptor Coregulators	47
A review of the immunomodulatory activities of polysaccharides isolated from Panax species	45
Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt1	45
Ginsenoside Ro, an oleanolic saponin of Panax ginseng, exerts anti-inflammatory effect by direct inhibiting toll like receptor 4 signaling pathway	42
Korean Red Ginseng saponin fraction exerts anti-inflammatory effects by targeting the NF-κB and AP-1 pathways	42
Inhibitory effect of ginsenglactone A from Panax ginseng on the tube formation of human umbilical vein endothelial cells and migration of human ovarian cancer cells	41
Ginsenoside Rg5 modulates the TLR4 and BCL-2 pathways by inhibiting NOX1, thereby alleviating inflammation, apoptosis and pyroptosis in hyperuricemia nephropathy	40
Protective effects of Panax ginseng berry extract on blue light-induced retinal damage in ARPE-19 cells and mouse retina	39
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway	39
Ginsenoside Rg3-enriched Korean Red Ginseng extract attenuates Non-Alcoholic Fatty Liver Disease by way of suppressed VCAM-1 expression in liver sinusoidal endothelium	37
Production and characterization of lentivirus vector-based SARS-CoV-2 pseudoviruses with dual reporters: Evaluation of anti-SARS-CoV-2 viral effect of Korean Red Ginseng	37

Korean Red Ginseng and Rb1 restore altered social interaction, gene expressions in the medial prefrontal cortex, and gut metabolites under post-weaning social isolation in mice	36
Assessing systemic, developmental, and reproductive toxicity and estrogenicity of Korean red ginseng extract G1899 in juvenile Sprague-Dawley Rats	35
Korean Red Ginseng extract treatment prevents post-antibiotic dysbiosis-induced bone loss in mice	34
Exploring the potential of ginseng-derived compounds in treating cancer cachexia	34
Safety of red ginseng and herb extract complex (RHC) in menopausal women: A randomized, double-blind, placebo-controlled trial	31
Renoprotective mechanisms of bioconverted wild-simulated ginseng: mitigating oxidative stress, inflammation, and apoptosis to protect against ischemic renal injury via Nrf2/HO-1/NF-κB/Caspase-3 signal	31
Korean Red Ginseng slows coreceptor switch in HIV-1 infected patients	30
20 (S)-ginsenoside Rh2 inhibits colorectal cancer cell growth by suppressing the Axl signaling pathway in vitro and in vivo	30
Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway	29
The dehiscence process in Panax ginseng seeds and the stigmasterol biosynthesis pathway in terms of metabolomics	29
Corrigendum to “Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2”[J Ginseng Res 45(5) September 202	29
Effects of Korean red ginseng on T-cell repopulation after autologous hematopoietic stem cell transplantation in childhood cancer patients	28
Compound K-enriched Korean red ginseng prevents lung cancer progression by targeting cancer cells and fibroblasts	28
Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy	27
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway	27
20(S)-ginsenoside Rh2 ameliorates ATRA resistance in APL by modulating lactylation-driven METTL3	27
Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD	27
Ginsenoside compound K reduces ischemia/reperfusion-induced neuronal apoptosis by inhibiting PTP1B-mediated IRS1 tyrosine dephosphorylation	26
Neuroprotective effect of Korean Red Ginseng against single prolonged stress-induced memory impairments and inflammation in the rat brain associated with BDNF expression	24
Long-term administration of red ginseng non-saponin fraction rescues the loss of skeletal muscle mass and strength associated with aging in mice	24
Ginsenoside Re prevents 3-methyladenine-induced catagen phase acceleration by regulating Wnt/β-catenin signaling in human dermal papilla cells	24
Evaluation of storage period of fresh ginseng for quality improvement of dried and red processed varieties	23
Corrigendum to “Nrf2-mediated activation of HO-1 is required in the blocking effect of compound K, a ginseng saponin metabolite, against oxidative stress damage in ARPE-19 human retinal pigment epithe	23
Antiviral effects of Korean Red Ginseng on human coronavirus OC43	23
Ginsenosides repair UVB-induced skin barrier damage in BALB/c hairless mice and HaCaT keratinocytes	22
Ginseng root-derived exosome-like nanoparticles protect skin from UV irradiation and oxidative stress by suppressing activator protein-1 signaling and limiting the generation of reactive oxygen specie	22
Editorial Board	21
Corrigendum to ‘Reciprocal regulation of SIRT1 and AMPK by Ginsenoside compound K impedes the conversion from plasma cells to mitigate for podocyte injury in MRL/lpr mice in a B cell-specific manner’	21
Ginsenoside Rc prevents dexamethasone-induced muscle atrophy and enhances muscle strength and motor function	20
Bacterial endophytes from ginseng and their biotechnological application	20
Maltol, a compound in Korean Red Ginseng, attenuates the Staphylococcus aureus–induced inflammasome activation in the skin	20
Sustainable production of natural products using synthetic biology: Ginsenosides	20
Enhancing effect of Panax ginseng on Zip4-mediated zinc influx into the cytosol	20
Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489/myd88/NF-κB pathway	20
Comprehensive understanding and underlying molecular mechanisms of the adaptogenic effects of Panax ginseng	19
Ginsenoside Rh2 reduces depression in offspring of mice with maternal toxoplasma infection during pregnancy by inhibiting microglial activation via the HMGB1/TLR4/NF-κB signaling pathway	19
Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability	18
Biodistribution and pharmacokinetic evaluation of Korean Red Ginseng components using radioisotopes in a rat model	18
Effects of Panax species and their bioactive components on allergic airway diseases	18
Corrigendum to “Panax notoginseng saponins promotes angiogenesis after cerebral ischemia-reperfusion injury”[J Ginseng Res 48(6), November 2024, 592–602]	18
Panax ginseng alleviates diabetic peripheral neuropathy by suppressing mitochondrial dysfunction and oxidative stress via modulation of the RAGE, NF-κB, and Nrf2 pathways	18
Panax ginseng as a potential therapeutic for neurological disorders associated with COVID-19; Toward targeting inflammasome	18
Effects of red ginseng on gut, microbiota, and brain in a mouse model of post-infectious irritable bowel syndrome	18
The role of ginseng and ginsenosides in ROS and cardiovascular disease	18
Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals	18
Effects of Korean red ginseng on auditory, cognitive, and liver functions in a naturally aged mouse model	17
20(S)-ginsenoside Rg3 exerts anti-fibrotic effect after myocardial infarction by alleviation of fibroblasts proliferation and collagen deposition through TGFBR1 signaling pathways	17
Editorial Board	17
Structural analysis, anti-inflammatory activity of the main water-soluble acidic polysaccharides (AGBP-A3) from Panax quinquefolius L berry	17
Prophylactic role of Korean Red Ginseng in astrocytic mitochondrial biogenesis through HIF-1α	17

Microbiota, co-metabolites, and network pharmacology reveal the alteration of the ginsenoside fraction on inflammatory bowel disease	16
Ginsenoside Rg1 treatment protects against cognitive dysfunction via inhibiting PLC–CN–NFAT1 signaling in T2DM mice	16
Korean red ginseng mitigates pulmonary injury and enhances antiviral immunity in a low-dose pseudo-type SARS-CoV-2 infection model	16
Multi-omics and compositional analysis of bidirectional solid fermentation products from Cordyceps militaris and Panax quinquefolius L	16
Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat	16
Comment on antiviral activities of ginseng and putative benefits against monkeypox virus	16
Rg3-enriched red ginseng extracts enhance apoptosis in CoCl2-stimulated breast cancer cells by suppressing autophagy	15
Korean Red ginseng supplements improve quality of life in patients with mild chronic pancreatitis symptoms: A prospective clinical trial	15
Ginseng-derived nanoparticles induce skin cell proliferation and promote wound healing	15
Editorial Board	15
Corrigendum to “Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2” [J. Ginseng Res. 47 (1) (January	15
The ways for ginsenoside Rh2 to fight against cancer: the molecular evidences in vitro and in vivo.	15
Compositional changes and physiological activities of fresh ginseng extracts prepared at various temperatures in subcritical water	15
Ginsenoside Re promotes osteogenic differentiation via BMP2/p38 pathway in vivo and in vitro	15
Exploring the Panax ginseng Meyer soil metagenome to uncover antagonistic bacteria against ginseng root rot disease	14
Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134–mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression	14
Impact of HIV-1 subtypes on gross deletion in the nef gene after Korean Red Ginseng treatment	14
Ginseng and ginseng byproducts for skincare and skin health	14
Comparative transcriptome and metabolome analyses of four Panax species explore the dynamics of metabolite biosynthesis	14
Ginsenoside Rg3 in combination with artesunate overcomes sorafenib resistance in hepatoma cell and mouse models	14
Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation	14
Antiviral activities of ginseng and its potential and putative benefits against monkeypox virus: A mini review	14
Red ginseng extract inhibits lipopolysaccharide-induced platelet–leukocyte aggregates in mice	13
Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice	13
Growth promotion effect of red ginseng dietary fiber to probiotics and transcriptome analysis of Lactiplantibacillus plantarum	13
Korean Red Ginseng alleviates dextran sodium sulfate-induced colitis through gut microbiota modulation in mice	13
Ginsenoside Rk1 inhibits HeLa cell proliferation through an endoplasmic reticulum signaling pathway	13
Effects of red ginseng oil(KGC11o) on testosterone-propionate-induced benign prostatic hyperplasia	12
P-hydroxybenzoic acid positively affect the Fusarium oxysporum to stimulate root rot in Panax notoginseng	12
Potential benefits of ginseng against COVID-19 by targeting inflammasomes	12
Panax ginseng: A modulator of amyloid, tau pathology, and cognitive function in Alzheimer's disease	12
The effects of Korean Red Ginseng on heme oxygenase-1 with a focus on mitochondrial function in pathophysiologic conditions	12
Inhalation of panaxadiol alleviates lung inflammation via inhibiting TNFA/TNFAR and IL7/IL7R signaling between macrophages and epithelial cells	12
Therapeutic potential of ginsenosides in circadian rhythm-based skin disorders	12
Korean Red Ginseng and Rb1 facilitate remyelination after cuprizone diet-induced demyelination	12
The beneficial potential of ginseng for menopause	12
Ginsenoside compound K ameliorates palmitate-induced atrophy in C2C12 myotubes via promyogenic effects and AMPK/autophagy-mediated suppression of endoplasmic reticulum stress	12
Letter to Editor: Antiviral activities of ginseng and its potential benefit against monkeypox virus: A mini review	12
Cognitive function improvement effects of gintonin-enriched fraction in subjective memory impairment: An assessor- and participant-blinded placebo-controlled study	12
Visualization of the binding between gintonin, a Panax ginseng-derived LPA receptor ligand, and the LPA receptor subtypes and transactivation of the EGF receptor	12
Effect of ginseng and ginsenosides on attention deficit hyperactivity disorder: A systematic review	12
Ginsenoside F1 Attenuates Eosinophilic Inflammation in Chronic Rhinosinusitis by Promoting NK Cell Function	12
Editorial Board	12
Compound K attenuates hyperglycemia by enhancing glucagon-like peptide-1 secretion through activating TGR5 via the remodeling of gut microbiota and bile acid metabolism	12
Synergistic effects of ginsenoside Rb1 and peroxiredoxin 6 in enhancing myocardial injury treatment through anti-inflammatory, anti-oxidative, and anti-apoptotic mechanisms	12
The necessity of eliminating the interference of panaxatriol saponins to maximize the preventive effect of panaxadiol saponins against Parkinson's disease in rats	11
Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy	11
High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture	11
Skin wound healing effects of (+)-syringaresinol from ginseng berry	11
Corrigendum to’ Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice’ [Journal of Ginseng Research Volume 46, Issue 6	11
Ginsenoside compound K reduces the progression of Huntington's disease via the inhibition of oxidative stress and overactivation of the ATM/AMPK pathway	11
Editorial Board	11
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways	11
The effects of Korean Red Ginseng on stress-related neurotransmitters and gene expression: A randomized, double-blind, placebo-controlled trial	11
Can Panax ginseng help control cytokine storm in COVID-19?	11
Ginsenoside Rg1 Epigenetically Modulates Smad7 Expression in Liver Fibrosis via MicroRNA-152	11
Pharmacokinetics and pharmacological activities of protopanaxatriol	10
Metabolism and drug interactions of Korean ginseng based on the pharmacokinetic properties of ginsenosides: Current status and future perspectives	10
Ginsenoside Rg5 promotes muscle regeneration via p38MAPK and Akt/mTOR signaling	10
Methanol-involved heterogeneous transformation of ginsenoside Rb1 to rare ginsenosides using heteropolyacids embedded in mesoporous silica with HPLC-MS investigation	10
Foeniculum vulgare essential oil nanoemulsion inhibits Fusarium oxysporum causing Panax notoginseng root-rot disease	10
The clearing-up of misunderstanding on body temperature changes and heat responses after Panax ginseng or Panax quinquefolium intake	10
Discovery and validation of PURA as a transcription target of 20(S)-protopanaxadiol: Implications for the treatment of cognitive dysfunction	9
Ginsenoside Re Mitigates Aβ1-42-induced Neurotoxicity by Promoting Autophagy and Suppressing NLRP3 Inflammasome	9
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway	9
Ginsenoside Rg3-enriched red ginseng extract mitigates sepsis by inhibiting platelet–leukocyte aggregates and regulates thrombo-inflammatory pathways	9
Ginsenoside 20(S)-Rg3 reduces KIF20A expression and promotes CDC25A proteasomal degradation in epithelial ovarian cancer	9
Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression	9
Enhanced immunity effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial	9
Korean Red Ginseng extract ameliorates demyelination by inhibiting infiltration and activation of immune cells in cuprizone-administrated mice	9
Nitrate enhances the secondary growth of storage roots in Panax ginseng	9
Gintonin, a Panax ginseng-derived LPA receptor ligand, attenuates kainic acid-induced seizures and neuronal cell death in the hippocampus via anti-inflammatory and anti-oxidant activities	9
Ginsenoside F2 enhances glucose metabolism by modulating insulin signal transduction in human hepatocarcinoma cells	9
Ginsenoside Rg5 enhances Abemaciclib sensitivity in ER+ breast cancer by modulating cell cycle proteins via transcriptional and post-translational levels	9
Recent progress (2015–2020) in the investigation of the pharmacological effects and mechanisms of ginsenoside Rb1, a main active ingredient in Panax ginseng Meyer	9
Panaxadiol promotes angiogenesis against chronic cerebral hypoperfusion injury through the VEGF-A/p38 MAPK/Src signaling pathway	9
Synergetic effect of soluble whey protein hydrolysate and Panax ginseng berry extract on muscle atrophy in hindlimb-immobilized C57BL/6 mice	9
Editorial Board	9
Regulation of appetite-related neuropeptides by Panax ginseng: A novel approach for obesity treatment	8
Protective effects of ginsenosides in cerebral small vessel disease: Cellular and molecular mechanisms	8

Modification of ginsenoside saponin composition via the CRISPR/Cas9-mediated knockout of protopanaxadiol 6-hydroxylase gene in Panax ginseng	8
Human disease-related long noncoding RNAs: Impact of ginsenosides	8
Ginsenoside Rb2: A review of pharmacokinetics and pharmacological effects	8
Effects of Panax ginseng on hyperglycemia, hypertension, and hyperlipidemia: A systematic review and meta-analysis	8
Comparative antiplatelet and antithrombotic effects of red ginseng and fermented red ginseng extracts	8
20(S)-Ginsenoside Rh2 induces apoptosis and autophagy in melanoma cells via suppressing Src/STAT3 signaling	8
Total ginsenosides and ginsenoside Rb2 delay hepatocyte senescence by regulating NAD+ metabolism and promoting IDO2/QPRT expression	8
Identification of a key signaling network regulating perennating bud dormancy in Panax ginseng	8
Amelioration of colitis progression by ginseng-derived exosome-like nanoparticles through suppression of inflammatory cytokines	8
COVID-19 infection and ginseng: Predictive influenza virus strains and non-predictive COVID-19 vaccine strains	8
In silico investigation of Panax ginseng lead compounds against COVID-19 associated platelet activation and thromboembolism	8
Panax ginseng exerts cardioprotective effect post myocardial infarction by attenuating myocardial fibrosis and inflammation through SIRT1 signaling pathways	8
Ginsenoside Rg1 exerts antidepressant effect by regulating hepatic kynurenine metabolism through promoting the interaction between HNF4α and PGC1α	8
Korean Red Ginseng, a regulator of NLRP3 inflammasome, in the COVID-19 pandemic	8
Roles of ginsenosides in sepsis	7
Rare ginsenosides transformed from stems and leaves of Panax ginseng reverse obesity by promoting browning of white fat through PKA/CREB pathway via REGγ negative regulation	7
Enzymatic bioconversion of ginseng powder increases the content of minor ginsenosides and potentiates immunostimulatory activity	7
Ginsenosides for the treatment of insulin resistance and diabetes: Therapeutic perspectives and mechanistic insights	7
Respiratory protective effects of Korean Red Ginseng in a mouse model of particulate matter 4-induced airway inflammation	7
The molecular mechanism of ginsenoside Rh2 and its octyl ester derivative on anti-angiogenesis in cancer treatment: The battle between PI3K and ROS	7
Emerging evidence that ginseng components improve cognition in subjective memory impairment, mild cognitive impairment, and early Alzheimer's disease dementia	7
The potential inhibitory effect of ginsenoside Rh2 on mitophagy in UV-irradiated human dermal fibroblasts	7
Ginsenoside Rg2, a principal effective ingredient of Panax ginseng, attenuates DSS-induced ulcerative colitis through NF-κB/NLRP3 pathway	7
Safety and antifatigue effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial	7
Ginsenoside Rb2 suppresses cellular senescence of human dermal fibroblasts by inducing autophagy	7
Potential application of ginseng in sepsis:	7
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization	7
Visualizing the distributions and spatiotemporal changes of metabolites in Panax notoginseng by MALDI mass spectrometry imaging	7
Effect of fermented red ginseng on gut microbiota dysbiosis- or immobilization stress-induced anxiety, depression, and colitis in mice	7
Corrigendum to ‘Effect of fermented red ginseng on gut microbiota dysbiosis- or immobilization stress-induced anxiety, depression, and colitis in mice’[Journal of Ginseng Research Volume 47, Issue 2,	7