Journal of Ginseng Research

Papers
(The median citation count of Journal of Ginseng Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Corrigendum to “Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitro and in vivo models” [J Ginseng Res 46 (2022) 426-434]119
Korean Red Ginseng water extract inhibits cadmium-induced lung injury via suppressing MAPK/ERK1/2/AP-1 pathway106
Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathways99
Anti-thrombotic effects of ginsenoside Rk3 by regulating cAMP and PI3K/MAPK pathway on human platelets88
Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg168
The necrotroph Botrytis cinerea promotes disease development in Panax ginseng by manipulating plant defense signals and antifungal metabolites degradation67
Ginsenoside Rg5, a potent agonist of Nrf2, inhibits HSV-1 infection-induced neuroinflammation by inhibiting oxidative stress and NF-κB activation62
Ginsenoside Rh2 alleviates inflammatory response and enhances motor function recovery in spinal cord injury mice via the ROS/MAPK14 signaling pathway57
Ginsenoside Rb1 attenuates coronary microvascular inflammatory injury via NDUFS4-SIRT5-DUSP1-mediated mitochondrial quality control in a murine ischemia-reperfusion model55
The antitumor effects and apoptotic mechanism of 20(S)-Protopanaxadiol in acute myeloid leukemia53
Inhibitory effect of ginsenglactone A from Panax ginseng on the tube formation of human umbilical vein endothelial cells and migration of human ovarian cancer cells51
Ginsenoside F2 Restrains Hepatic Steatosis and Inflammation by Altering the Binding Affinity of Liver X Receptor Coregulators45
Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt140
Panaxcerol D from Panax ginseng ameliorates the memory impairment induced by cholinergic blockade or Aβ25–35 peptide in mice40
Ginseng acetylcholine from various ginsengs and its in vivo physiological effect40
Ginsenoside Rg5 modulates the TLR4 and BCL-2 pathways by inhibiting NOX1, thereby alleviating inflammation, apoptosis and pyroptosis in hyperuricemia nephropathy39
Ginsenoside Rg3-enriched Korean Red Ginseng extract attenuates Non-Alcoholic Fatty Liver Disease by way of suppressed VCAM-1 expression in liver sinusoidal endothelium35
Production and characterization of lentivirus vector-based SARS-CoV-2 pseudoviruses with dual reporters: Evaluation of anti-SARS-CoV-2 viral effect of Korean Red Ginseng33
20(S)-protopanaxatriol alleviates gastritis by attenuating oxidative stress and inflammatory responses via inhibition of PI3K/AKT and JAK/STAT3 pathways32
Optimizing Component Formula Extracted from Ginseng and Salvia Inhibits Lung Cancer Metastasis and EMT via Suppressing AKT/GSK-3β/β-catenin Pathway31
Ginsenoside Rb1-engineered nanocomposite hydrogel promotes pressure injury repair through SIRT1-AMPK-mediated ferroptosis inhibition and angiogenesis activation31
Protective effects of Panax ginseng berry extract on blue light-induced retinal damage in ARPE-19 cells and mouse retina30
Panax ginseng as a microbial ecosystem modulator: implications for systemic health via the gut-organ axes30
Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway29
Effects of Korean red ginseng on T-cell repopulation after autologous hematopoietic stem cell transplantation in childhood cancer patients29
Quantitative description and microscopic mechanism of ginsenosides’ reactions during the thermal-driven processing of Panax ginseng28
Corrigendum to “Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2”[J Ginseng Res 45(5) September 20228
Targeting mitochondrial quality control: Ginsenoside Rg1 as a therapeutic candidate for neuromuscular diseases28
Renoprotective mechanisms of bioconverted wild-simulated ginseng: mitigating oxidative stress, inflammation, and apoptosis to protect against ischemic renal injury via Nrf2/HO-1/NF-κB/caspase-3 signal28
Korean Red Ginseng slows coreceptor switch in HIV-1 infected patients27
Korean Red Ginseng and Rb1 restore altered social interaction, gene expressions in the medial prefrontal cortex, and gut metabolites under post-weaning social isolation in mice27
Safety of red ginseng and herb extract complex (RHC) in menopausal women: A randomized, double-blind, placebo-controlled trial26
Korean Red Ginseng extract treatment prevents post-antibiotic dysbiosis-induced bone loss in mice26
Activation of BMPR1b–SMAD pathway by Ginsenoside F1 restores osteoblast function in ovariectomy-induced osteoporosis25
Antiplatelet activity of a Korean red ginseng–derived saponin fraction and its inhibition of influenza A virus–induced thrombosis25
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway25
Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD23
Assessing systemic, developmental, and reproductive toxicity and estrogenicity of Korean red ginseng extract G1899 in juvenile Sprague-Dawley Rats22
Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy22
Proteomic profiling reveals the mechanism of ginsenoside synthesis in Panax notoginseng22
Corrigendum to “Nrf2-mediated activation of HO-1 is required in the blocking effect of compound K, a ginseng saponin metabolite, against oxidative stress damage in ARPE-19 human retinal pigment epithe21
Compound K-enriched Korean red ginseng prevents lung cancer progression by targeting cancer cells and fibroblasts21
Exploring the potential of ginseng-derived compounds in treating cancer cachexia21
Ginsenoside Re prevents 3-methyladenine-induced catagen phase acceleration by regulating Wnt/β-catenin signaling in human dermal papilla cells21
Cytogenomic profiling of Panax ginseng cultivars and in vitro root cultures through multi-color PLOP-FISH and flow cytometry Reveals Somaclonal Variations21
Effects of Korean red ginseng on the HIV-1 env sequence length and CpG dinucleotides20
Long-term administration of red ginseng non-saponin fraction rescues the loss of skeletal muscle mass and strength associated with aging in mice20
Contemporary perceptions of ginseng among individuals with health needs: A nationwide questionnaire survey20
Ginsenoside Rg5 alleviates allergic rhinitis in rats by modulating nasal microbiota by inhibiting JAK2/STAT3/BCL-2 and MAPK signaling20
Antiviral effects of Korean Red Ginseng on human coronavirus OC4320
Comprehensive metabolomic profiling of Panax quinquefolius: qualitative and quantitative analysis across different habitats, harvesting seasons and parts by UPLC/Triple TOF-MS and UPLC/Qtrap-MS20
A review of pharmacological properties and pharmacokinetic of 20(S)-protopanaxadiol19
20(S)-ginsenoside Rh2 ameliorates ATRA resistance in APL by modulating lactylation-driven METTL319
Ginsenoside compound K reduces ischemia/reperfusion-induced neuronal apoptosis by inhibiting PTP1B-mediated IRS1 tyrosine dephosphorylation19
Ginseng root-derived exosome-like nanoparticles protect skin from UV irradiation and oxidative stress by suppressing activator protein-1 signaling and limiting the generation of reactive oxygen specie19
Effect of diabetes on the efficacy and safety of Panax notoginseng saponins in ischemic stroke: a prespecified analysis of the PANDA trial18
Ginsenoside Rh7 ameliorates myocardial injury in diabetic cardiomyopathy by promoting M2 polarization of macrophages via SIRT1/FOXO1/β-catenin18
Corrigendum to ‘Reciprocal regulation of SIRT1 and AMPK by Ginsenoside compound K impedes the conversion from plasma cells to mitigate for podocyte injury in MRL/lpr mice in a B cell-specific manner’ 18
Editorial Board18
Korean red ginseng extract inhibits microplastic translocation via the gut−liver axis by ameliorating alcohol-induced intestinal disruption17
Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489/myd88/NF-κB pathway17
Ginsenoside Rc prevents dexamethasone-induced muscle atrophy and enhances muscle strength and motor function17
Protopanaxatriol enhances mucin expression in intestinal epithelial cells and mice17
Maltol, a compound in Korean Red Ginseng, attenuates the Staphylococcus aureus–induced inflammasome activation in the skin17
Sustainable production of natural products using synthetic biology: Ginsenosides17
Ginseng nonsaponins: New insights into their pharmacological potentials in inflammasome-driven inflammation and immunopathology17
Comprehensive understanding and underlying molecular mechanisms of the adaptogenic effects of Panax ginseng17
Effects of Panax species and their bioactive components on allergic airway diseases16
Microbiome-mediated pharmacology of ginseng: Mechanistic insights into metabolic regulation and therapeutic potential16
Biodistribution and pharmacokinetic evaluation of Korean Red Ginseng components using radioisotopes in a rat model16
Panax ginseng as a potential therapeutic for neurological disorders associated with COVID-19; Toward targeting inflammasome16
Corrigendum to “Panax notoginseng saponins promotes angiogenesis after cerebral ischemia-reperfusion injury”[J Ginseng Res 48(6), November 2024, 592–602]16
Valorizing ginseng residues using dimethyl ether: Recovering functional lipids and ginsenosides16
Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals16
Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability16
Editorial Board15
Ginsenosides exhibit potential therapeutic potential in photoaging by regulating keratinocyte ferroptosis15
Panax ginseng alleviates diabetic peripheral neuropathy by suppressing mitochondrial dysfunction and oxidative stress via modulation of the RAGE, NF-κB, and Nrf2 pathways15
The role of ginseng and ginsenosides in ROS and cardiovascular disease15
Rg3-enriched red ginseng extracts enhance apoptosis in CoCl2-stimulated breast cancer cells by suppressing autophagy14
Ginsenoside Re promotes osteogenic differentiation via BMP2/p38 pathway in vivo and in vitro14
Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat14
Comment on antiviral activities of ginseng and putative benefits against monkeypox virus14
Microbiota, co-metabolites, and network pharmacology reveal the alteration of the ginsenoside fraction on inflammatory bowel disease14
Ginsenoside Rg1 treatment protects against cognitive dysfunction via inhibiting PLC–CN–NFAT1 signaling in T2DM mice14
20(S)-ginsenoside Rg3 exerts anti-fibrotic effect after myocardial infarction by alleviation of fibroblasts proliferation and collagen deposition through TGFBR1 signaling pathways14
Korean red ginseng mitigates pulmonary injury and enhances antiviral immunity in a low-dose pseudo-type SARS-CoV-2 infection model14
Editorial Board14
Anti-skin aging effects of black ginseng extracts through regulating inflammatory factors and the CLOCK–ERK pathway in mice14
The ways for ginsenoside Rh2 to fight against cancer: the molecular evidences in vitro and in vivo.14
Structural analysis, anti-inflammatory activity of the main water-soluble acidic polysaccharides (AGBP-A3) from Panax quinquefolius L berry14
Red ginseng-mediated modulation of the NLRP3 Inflammasome in neuroinflammatory-related cognitive impairments14
Multi-omics and compositional analysis of bidirectional solid fermentation products from Cordyceps militaris and Panax quinquefolius L13
Comparative transcriptome and metabolome analyses of four Panax species explore the dynamics of metabolite biosynthesis13
Korean Red ginseng supplements improve quality of life in patients with mild chronic pancreatitis symptoms: A prospective clinical trial13
Effects of Korean red ginseng on auditory, cognitive, and liver functions in a naturally aged mouse model13
Impact of HIV-1 subtypes on gross deletion in the nef gene after Korean Red Ginseng treatment13
Corrigendum to “Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2” [J. Ginseng Res. 47 (1) (January 13
Antiviral activities of ginseng and its potential and putative benefits against monkeypox virus: A mini review13
Ginseng-derived nanoparticles induce skin cell proliferation and promote wound healing13
Compositional changes and physiological activities of fresh ginseng extracts prepared at various temperatures in subcritical water13
Ginsenoside RK3 attenuates isoproterenol-induced heart failure in mice through AMPK/Sirt1/PGC-1α pathway activation13
Effect of Korean red ginseng on deep capillary plexus parameters in diabetic retinopathy: A prospective, randomized, double-blind clinical trial12
Cognitive function improvement effects of gintonin-enriched fraction in subjective memory impairment: An assessor- and participant-blinded placebo-controlled study12
Growth promotion effect of red ginseng dietary fiber to probiotics and transcriptome analysis of Lactiplantibacillus plantarum12
Red ginseng extract inhibits lipopolysaccharide-induced platelet–leukocyte aggregates in mice12
Gintonin prevents paclitaxel-induced neuropathic pain via spinal LPA3 receptors and oligodendrocyte precursor cells in mice12
Ginsenoside Rk1 inhibits HeLa cell proliferation through an endoplasmic reticulum signaling pathway12
Inhalation of panaxadiol alleviates lung inflammation via inhibiting TNFA/TNFAR and IL7/IL7R signaling between macrophages and epithelial cells12
Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation12
Exploring the Panax ginseng Meyer soil metagenome to uncover antagonistic bacteria against ginseng root rot disease11
Korean Red Ginseng and Rb1 facilitate remyelination after cuprizone diet-induced demyelination11
Yin and Yang of Ginsenosides: Molecular Mechanisms of Bidirectional Regulation of Angiogenesis11
P-hydroxybenzoic acid positively affect the Fusarium oxysporum to stimulate root rot in Panax notoginseng11
Ginseng and ginseng byproducts for skincare and skin health11
The beneficial potential of ginseng for menopause11
Therapeutic potential of ginsenosides in circadian rhythm-based skin disorders11
Synergistic effects of ginsenoside Rb1 and peroxiredoxin 6 in enhancing myocardial injury treatment through anti-inflammatory, anti-oxidative, and anti-apoptotic mechanisms11
Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice11
Korean Red Ginseng alleviates dextran sodium sulfate-induced colitis through gut microbiota modulation in mice11
Mechanisms of yield and quality enhancement in Panax Vietnamensis: A comparison of three artificial cultivation models11
Potential benefits of ginseng against COVID-19 by targeting inflammasomes11
The effects of Korean Red Ginseng on heme oxygenase-1 with a focus on mitochondrial function in pathophysiologic conditions10
Editorial Board10
Panax ginseng: A modulator of amyloid, tau pathology, and cognitive function in Alzheimer's disease10
Efficacy and safety of Korean Red Ginseng as adjunctive therapy in type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial10
Letter to Editor: Antiviral activities of ginseng and its potential benefit against monkeypox virus: A mini review10
Ginsenoside Rs3 (G-Rs3) inhibits agonist- and oxLDL-mediated platelet activation and attenuates in vivo arterial thrombosis10
Korean Red Ginseng attenuates glucocorticoid-induced skin barrier dysfunction via mineralocorticoid receptor modulation10
Effect of ginseng and ginsenosides on attention deficit hyperactivity disorder: A systematic review10
Compound K attenuates hyperglycemia by enhancing glucagon-like peptide-1 secretion through activating TGR5 via the remodeling of gut microbiota and bile acid metabolism10
Gintonin, a Panax ginseng-derived LPA receptor ligand, attenuates kainic acid-induced seizures and neuronal cell death in the hippocampus via anti-inflammatory and anti-oxidant activities9
A novel black ginseng processing method for optimizing rare ginsenosides with bioactivity and sustainability9
Ginsenoside Rg5 promotes muscle regeneration via p38MAPK and Akt/mTOR signaling9
The effects of Korean Red Ginseng on stress-related neurotransmitters and gene expression: A randomized, double-blind, placebo-controlled trial9
Ginsenoside Rg1 Epigenetically Modulates Smad7 Expression in Liver Fibrosis via MicroRNA-1529
Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy9
Editorial Board9
Efficacy of ginseng in cardiovascular disease prevention and treatment: An analysis of research from 1998 to 2025 based on the database9
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways9
Skin wound healing effects of (+)-syringaresinol from ginseng berry9
Dual-targeted liposomes delivering ginsenoside CK attenuate cerebral ischemia-reperfusion injury by suppressing PANoptosis via O-GlcNAcylation of RIPK1/RIPK39
The necessity of eliminating the interference of panaxatriol saponins to maximize the preventive effect of panaxadiol saponins against Parkinson's disease in rats9
The clearing-up of misunderstanding on body temperature changes and heat responses after Panax ginseng or Panax quinquefolium intake9
Ginsenoside 20(S)-Rg3 reduces KIF20A expression and promotes CDC25A proteasomal degradation in epithelial ovarian cancer9
Corrigendum to’ Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice’ [Journal of Ginseng Research Volume 46, Issue 69
Metagenomics reveals an interaction among rhizosphere microbial community, soil properties and active ingredients in a medicinal crop Panax notoginseng9
Korean red ginseng extract ameliorates high-fat diet-induced hyperlipidemia by modulating the gut microbiota-liver metabolic axis9
Pharmacokinetics and pharmacological activities of protopanaxatriol8
Metabolism and drug interactions of Korean ginseng based on the pharmacokinetic properties of ginsenosides: Current status and future perspectives8
Ginsenoside F2 enhances glucose metabolism by modulating insulin signal transduction in human hepatocarcinoma cells8
Ginsenoside compound K reduces the progression of Huntington's disease via the inhibition of oxidative stress and overactivation of the ATM/AMPK pathway8
Foeniculum vulgare essential oil nanoemulsion inhibits Fusarium oxysporum causing Panax notoginseng root-rot disease8
Ginsenoside Re mitigates Aβ1-42-induced neurotoxicity by promoting autophagy and suppressing NLRP3 inflammasome8
Korean Red Ginseng extract ameliorates demyelination by inhibiting infiltration and activation of immune cells in cuprizone-administrated mice8
Methanol-involved heterogeneous transformation of ginsenoside Rb1 to rare ginsenosides using heteropolyacids embedded in mesoporous silica with HPLC-MS investigation8
Editorial Board8
Ginsenoside Rg3-enriched red ginseng extract mitigates sepsis by inhibiting platelet–leukocyte aggregates and regulates thrombo-inflammatory pathways8
Enhanced immunity effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial7
Regulation of appetite-related neuropeptides by Panax ginseng: A novel approach for obesity treatment7
Context-dependent modulation of the TAK1–MAPK axis by ginsenoside-based formulations along the NAFLD–HCC continuum7
Ginsenoside Re regulates PFKFB3-mediated glycolysis to inhibit endothelial cell migration to ameliorate atherosclerosis7
Ginsenoside Rb1 inhibits oxidative stress and ferroptosis to alleviate salpingitis infertility by down-regulating PTGS2 and up-regulating GPX47
Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression7
Discovery and validation of PURA as a transcription target of 20(S)-protopanaxadiol: Implications for the treatment of cognitive dysfunction7
Ginsenoside Rg5 enhances Abemaciclib sensitivity in ER+ breast cancer by modulating cell cycle proteins via transcriptional and post-translational levels7
Nitrate enhances the secondary growth of storage roots in Panax ginseng7
Clinical randomized controlled trial and network pharmacological analysis of blood glucose regulation by Korean red ginseng in patients with type 2 diabetes and impaired glucose regulation7
Recombinant single-chain variable fragment-based immunoassay for the authentication of Vietnamese ginseng via quantitative detection of majonoside R27
Ginsenosides: potential therapeutic agents against hepatic fibrosis7
In silico investigation of Panax ginseng lead compounds against COVID-19 associated platelet activation and thromboembolism7
Ginsenoside Rb1 restores dental pulp by promoting odontogenic differentiation of dental pulp stem cells via the TGF-β/Smad signaling pathway7
COVID-19 infection and ginseng: Predictive influenza virus strains and non-predictive COVID-19 vaccine strains7
Panaxadiol promotes angiogenesis against chronic cerebral hypoperfusion injury through the VEGF-A/p38 MAPK/Src signaling pathway7
Ginsenoside Rg1 exerts antidepressant effect by regulating hepatic kynurenine metabolism through promoting the interaction between HNF4α and PGC1α6
20(S)-Ginsenoside Rh2 induces apoptosis and autophagy in melanoma cells via suppressing Src/STAT3 signaling6
Amelioration of colitis progression by ginseng-derived exosome-like nanoparticles through suppression of inflammatory cytokines6
Contemporary utilization of ginseng among individuals with health needs: A nationwide questionnaire survey6
Panax ginseng exerts cardioprotective effect post myocardial infarction by attenuating myocardial fibrosis and inflammation through SIRT1 signaling pathways6
Human disease-related long noncoding RNAs: Impact of ginsenosides6
Modification of ginsenoside saponin composition via the CRISPR/Cas9-mediated knockout of protopanaxadiol 6-hydroxylase gene in Panax ginseng6
Total ginsenosides and ginsenoside Rb2 delay hepatocyte senescence by regulating NAD+ metabolism and promoting IDO2/QPRT expression6
Efficacy of Panax notoginseng saponins on functional outcome in obese patients with acute ischemic stroke6
Protective effects of ginsenosides in cerebral small vessel disease: Cellular and molecular mechanisms6
Identification of a key signaling network regulating perennating bud dormancy in Panax ginseng6
Mechanistic insights into the regulation of glucose‒lipid metabolism by the bioactive constituents of ginseng6
The potential inhibitory effect of ginsenoside Rh2 on mitophagy in UV-irradiated human dermal fibroblasts5
Safety and antifatigue effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial5
Effect of fermented red ginseng on gut microbiota dysbiosis- or immobilization stress-induced anxiety, depression, and colitis in mice5
Corrigendum to ‘Effect of fermented red ginseng on gut microbiota dysbiosis- or immobilization stress-induced anxiety, depression, and colitis in mice’[Journal of Ginseng Research Volume 47, Issue 2, 5
The cardioprotective mechanism of total saponins from mountain cultivated ginseng against doxorubicin-induced heart failure: Insights from gut-heart axis modulation based on gut microbiota and fecal m5
Ginsenoside Rg1 enhances stem cell abundance in aging human skeletal muscle after resistance exercise5
Li-ginseng powder alleviates cancer cachexia in mice by regulating the ubiquitin-proteasome pathway and reducing inflammation5
Emerging evidence that ginseng components improve cognition in subjective memory impairment, mild cognitive impairment, and early Alzheimer's disease dementia5
Roles of ginsenosides in sepsis5
Editorial Board5
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization5
Potential application of ginseng in sepsis:5
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