Allergology International

Article	Citations
Japanese guidelines for food allergy 2020	136
Japanese guidelines for allergic rhinitis 2020	118
Japanese guidelines for atopic dermatitis 2020	106
The roles of IL-5 and anti-IL-5 treatment in eosinophilic diseases: Asthma, eosinophilic granulomatosis with polyangiitis, and eosinophilic chronic rhinosinusitis	102
Mechanisms of allergen-specific immunotherapy and allergen tolerance	90
Japanese guidelines for adult asthma 2020	89
Subtypes of atopic dermatitis: From phenotype to endotype	86
Innovation in the treatment of atopic dermatitis: Emerging topical and oral Janus kinase inhibitors	60
Dupilumab: Basic aspects and applications to allergic diseases	60
Anti-TSLP antibodies: Targeting a master regulator of type 2 immune responses	58
Allergy to COVID-19 vaccines: A current update	57
Roles of omalizumab in various allergic diseases	57
Epidemiological aspects of allergic conjunctivitis	55
Skin microbiome of atopic dermatitis	53
Hydrogen sulfide as a novel biomarker of asthma and chronic obstructive pulmonary disease	48
How to detect eosinophil ETosis (EETosis) and extracellular traps	41
IL-24: A new player in the pathogenesis of pro-inflammatory and allergic skin diseases	40
Recent developments and advances in atopic dermatitis and food allergy	40
Peripheral itch sensitization in atopic dermatitis	39
The multiple functions and subpopulations of eosinophils in tissues under steady-state and pathological conditions	37
Immune-related adverse events in various organs caused by immune checkpoint inhibitors	36
Japanese guidelines for allergic conjunctival diseases 2020	34
Slow low-dose oral immunotherapy: Threshold and immunological change	31
Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins	31
Skin barrier defects in atopic dermatitis: From old idea to new opportunity	30

Eosinophils: Cells known for over 140 years with broad and new functions	29
New medical big data for P4 medicine on allergic conjunctivitis	28
Increased CD69 expression on activated eosinophils in eosinophilic chronic rhinosinusitis correlates with clinical findings	28
Implications of IL-13Rα2 in atopic skin inflammation	26
Japanese guidelines for childhood asthma 2020	26
Biologics for severe asthma: The real-world evidence, effectiveness of switching, and prediction factors for the efficacy	25
Effect of oral immunotherapy in children with milk allergy: The ORIMA study	23
Japanese cedar and cypress pollinosis updated: New allergens, cross-reactivity, and treatment	23
Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases	21
Hyper-IgE syndrome, 2021 update	21
Ocular allergy test and biomarkers on the ocular surface: Clinical test for evaluating the ocular surface condition in allergic conjunctival diseases	20
Screening and diagnosis of acute and chronic bird-related hypersensitivity pneumonitis by serum IgG and IgA antibodies to bird antigens with ImmunoCAP®	19
Exacerbating factors and disease burden in patients with atopic dermatitis	19
Gut microbiota and allergic diseases in children	18
Early introduction of very small amounts of multiple foods to infants: A randomized trial	18
Individual characteristics and associated factors of hay fever: A large-scale mHealth study using AllerSearch	18
Rapid clearance of mepolizumab-resistant bronchial mucus plugs in allergic bronchopulmonary aspergillosis with benralizumab treatment	17
Epidemiological study of oral allergy syndrome in birch pollen dispersal-free regions	17
Chronic urticaria and the pathogenic role of mast cells	17
A novel deep intronic SERPING1 variant as a cause of hereditary angioedema due to C1-inhibitor deficiency	17
Neuro-allergology: Mast cell–nerve cross-talk	16
Mortality and risk factors on admission in toxic epidermal necrolysis: A cohort study of 59 patients	15
The diagnosis and treatment of hereditary angioedema patients in Japan: A patient reported outcome survey	15
Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2021	15
Dupilumab efficacy and safety in Japanese patients with uncontrolled, moderate-to-severe asthma in the phase 3 LIBERTY ASTHMA QUEST study	14
Drug-induced scleroderma-like lesion	14
Early benralizumab for eosinophilic myocarditis in eosinophilic granulomatosis with polyangiitis	14
Cough persistence in adults with chronic cough: A 4-year retrospective cohort study	14
Comparison of sensitization and prevalence of Japanese cedar pollen and mite-induced perennial allergic rhinitis between 2006 and 2016 in hospital workers in Japan	14
Identification of peroxidase-1 and beta-glucosidase as cross-reactive wheat allergens in grass pollen-related wheat allergy	14
Executive summary: Japanese guidelines for allergic rhinitis 2020	14
Respiratory sensitization to insect allergens: Species, components and clinical symptoms	13
Conventional type 2 lung dendritic cells are potent inducers of follicular helper T cells in the asthmatic lung	13
Benralizumab as initial treatment for chronic eosinophilic pneumonia	13
Multiplex component-based allergen macroarray test is useful to predict clinical reactivity to tree nuts in children	13
Trained innate lymphoid cells in allergic diseases	13
Maternal exposure to smoking and infant's wheeze and asthma: Japan Environment and Children's Study	13
Serum polyethylene glycol-specific IgE and IgG in patients with hypersensitivity to COVID-19 mRNA vaccines	13
Two cases of dupilumab-associated eosinophilic pneumonia in asthma with eosinophilic chronic rhinosinusitis: IL-5-driven pathology?	12
Prevention of IL-6 signaling ameliorates toluene diisocyanate-induced steroid-resistant asthma	12
Cycling therapy with benralizumab and dupilumab for severe eosinophilic asthma with eosinophilic chronic rhinosinusitis and eosinophilic otitis media	12
In vivo visualization of eosinophil secretion in eosinophilic granulomatosis with polyangiitis: An ultrastructural study	11
Component-resolved diagnostics can be useful for identifying hazelnut allergy in Japanese children	11
Serum IgG4 as a biomarker reflecting pathophysiology and post-operative recurrence in chronic rhinosinusitis	11
Impact of the COVID-19 pandemic on asthma exacerbations in children: A multi-center survey using an administrative database in Japan	11
Management of hereditary angioedema in Japan: Focus on icatibant for the treatment of acute attacks	11
Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma	11
Thymus and activation-regulated chemokine (TARC/CCL17) predicts decline of pulmonary function in patients with chronic obstructive pulmonary disease	11
The understanding of asthma pathogenesis in the era of precision medicine	11
Real-life long-term safety and effectiveness of omalizumab in Japanese pediatric patients with severe allergic asthma: A post-marketing surveillance	11

ORMDL3/GSDMB genotype as a risk factor for early-onset adult asthma is linked to total serum IgE levels but not to allergic sensitization	11
Dupilumab-resistant facial erythema - Dermoscopic, histological and clinical findings of three patients	10
Biologics for allergy: therapeutic potential for ocular allergic diseases and adverse effects on the eye	10
Strategic Outlook toward 2030: Japan's research for allergy and immunology – Secondary publication	10
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with anticonvulsants in a Japanese population: Matched case–control and cohort studies	10
Drug allergy and autoimmune diseases	10
The effects of mepolizumab on peripheral circulation and neurological symptoms in eosinophilic granulomatosis with polyangiitis (EGPA) patients	10
Treatments of refractory eosinophilic lung diseases with biologics	10
Executive summary: Japanese guidelines for allergic conjunctival diseases 2021	10
Executive summary: Japanese guidelines for adult asthma (JGL) 2021	10
Multi-faceted regulation of IgE production and humoral memory formation	9
Combined assessment of serum eosinophil-derived neurotoxin and YKL-40 may identify Asthma-COPD overlap	9
Direct and indirect action modes of acetylcholine in cholinergic urticaria	9
Neuro-immune crosstalk and food allergy: Focus on enteric neurons and mucosal mast cells	9
Current summary of clinical studies on anti-TSLP antibody, Tezepelumab, in asthma	9
Optimal Aspergillus fumigatus and Asp f 1 serum IgG cut-offs for the diagnosis of allergic bronchopulmonary aspergillosis	9
Activated steady status and distinctive FcεRI-mediated responsiveness in basophils of atopic dermatitis	9
Control of immunity and allergy by steroid hormones	9
Cord blood eosinophilia precedes neonatal onset of food-protein-induced enterocolitis syndrome (FPIES)	9
Prevalence of inhaled allergen-specific IgE antibody positivity in the healthy Japanese population	9
Frailty and muscle weakness in elderly patients with asthma and their association with cumulative lifetime oral corticosteroid exposure	9
Relationship between gut microbiota composition and sensitization to inhaled allergens	9
Comprehensive hospital-based regional survey of anaphylaxis in Japanese children: Time trends of triggers and adrenaline use	8
Time will tell about mast cells: Circadian control of mast cell activation	8
Primary and pollen-associated hazelnut allergy in school-aged children in Germany: A birth cohort study	8
Asthma exacerbation associated with COVID-19 pneumonia	8
L-type amino acid transporter 1 (LAT1)-specific inhibitor is effective against T cell-mediated nasal hyperresponsiveness	8
Serum transglutaminase 2 activity as a potential biomarker of disease severity and response to omalizumab in chronic spontaneous urticaria	8
Efficacy of immunoglobulin replacement therapy and azithromycin in severe asthma with antibody deficiency	8
Efficacy of a house dust mite sublingual immunotherapy tablet as add-on dupilumab in asthma with rhinitis	8
Periostin is an aggravating factor and predictive biomarker of eosinophilic chronic rhinosinusitis	8
ILC2s in skin disorders	8
Propolis suppresses cytokine production in activated basophils and basophil-mediated skin and intestinal allergic inflammation in mice	8
Low-dose oral immunotherapy for walnut allergy with anaphylaxis: Three case reports	8
Inborn errors of immunity with eosinophilia	8
Efficacy, pharmacokinetics, and safety of icatibant for the treatment of Japanese patients with an acute attack of hereditary angioedema: A phase 3 open-label study	7
Interstitial pneumonitis after COVID-19 vaccination: A report of three cases	7
Clinical characteristics of patients with not well-controlled severe asthma in Japan: Analysis of the Keio Severe Asthma Research Program in Japanese population (KEIO-SARP) registry	7
Japanese cedar pollen sublingual immunotherapy is effective in treating seasonal allergic rhinitis during the pollen dispersal period for Japanese cedar and Japanese cypress	7
Neurodevelopment at 6 years of age in children with atopic dermatitis	7
Long-term treatment of Japanese cedar pollinosis with Japanese cedar pollen SLIT drops and persistence of treatment effect: A post-marketing clinical trial	7
Objective evaluation of allergic conjunctival disease (with a focus on the application of artificial intelligence technology)	7
Regional differences in the incidence of asthma exacerbations in Japan: A heat map analysis of healthcare insurance claims data	7
Determination of the cutoff values of Th2 markers for the prediction of future exacerbation in severe asthma: An analysis from the Hokkaido Severe Asthma Cohort Study	7
Components of plant-derived food allergens: Structure, diagnostics, and immunotherapy	7
The efficacy of off-label IL-5-modulating treatment in rare eosinophil-mediated diseases	7
Drug allergy and non-HIV immune reconstitution inflammatory syndrome	7
Effect of topical immunotherapy with squaric acid dibutylester for alopecia areata in Japanese patients	7
Drug-specific history, skin and in vitro tests can reduce the need for drug provocation tests in betalactam-hypersensitivity	6
Dupilumab therapy rapidly improved alopecia areata associated with trichotillomania in an atopic dermatitis patient	6
In vitro basophil activation is reduced by short-term omalizumab treatment in hydrolyzed wheat protein allergy	6
Clinical utility of the basophil activation test in the diagnosis of sweat allergy	6
Nattokinase (Bac s 1), a subtilisin family serine protease, is a novel allergen contained in the traditional Japanese fermented food natto	6
Poorly controlled asthma – Easy wins and future prospects for addressing fungal allergy	6
Reflux-related symptoms reflect poor asthma control and the presence of airway neuronal dysfunction	5
Efficacy of dupilumab and biomarkers for systemic corticosteroid naïve allergic bronchopulmonary mycosis	5
Anaphylaxis from nattokinase in a patient with fermented soybean (natto) allergy	5
Classifications of moderate to severe asthma phenotypes in Japan and analysis of serum biomarkers: A Nationwide Cohort Study in Japan (NHOM Asthma Study)	5
Pork-cat syndrome caused by ingestion of beef intestines in an 8-year-old child	5
Relationship between Aspergillus and asthma	5
Fluctuations of aeroallergen-specific immunoglobulins and children's allergic profiles: Japan Environment & Children's Study of a pilot cohort	5
A clinical and canine experimental study in small-airway response to bronchial thermoplasty: Role of the neuronal effect	5
Group 2 innate lymphoid cells in human asthma	5
Airway epithelial STAT3 inhibits allergic inflammation via upregulation of stearoyl-CoA desaturase 1	5
Pathogenic helper T cells	5
An asthmatic case of psoriasiform eruption caused by administration of dupilumab	5
Epinephrine autoinjector prescription patterns for severe anaphylactic patients in Japan: A retrospective analysis of health insurance claims data	5
A parvalbumin allergy case was successfully treated with oral immunotherapy using hypoallergenic fish	5
Dupilumab maintenance therapy in an asthmatic patient with coronavirus disease 2019 pneumonia	5
Exposure to cold airflow alters skin pH and epidermal filaggrin degradation products in children with atopic dermatitis	5
A diagnostic score for eosinophilic granulomatosis with polyangiitis among eosinophilic disorders	5
Biochemistry, molecular genetics, and clinical aspects of hereditary angioedema with and without C1 inhibitor deficiency	5
Type-I-hypersensitivity to 15 kDa, 28 kDa and 54 kDa proteins in vitellogenin specific to Gadus chalcogrammus roe	5
S100A8 enhances IL-1β production from nasal epithelial cells in eosinophilic chronic rhinosinusitis	5
A case of millet allergy that developed into wheat-induced anaphylaxis by cross-reaction between millet and wheat antigens	5
Current overview of the role of neuropeptides in ILC2s and future directions	5
Development of alopecia areata-like reactions in a patient treated with dupilumab	5
High histamine concentrations in human sweat in association with type I allergy to the semi-purified sweat antigen	5
A validation study of the Japanese version of the Angioedema Activity Score (AAS) and the Angioedema Quality of Life Questionnaire (AE-QoL)	5
Eczema phenotypes and IgE component sensitization in adolescents: A population-based birth cohort	5

Interleukin 2 receptor-α expression after lymphocyte stimulation for non-IgE-mediated gastrointestinal food allergies	5
Overweight improves long-term survival in Japanese patients with asthma	5
Time-restricted feeding in rest phase alters IgE/mast cell–mediated allergic reaction in mice	5
Is oral food challenge useful to avoid complete elimination in Japanese patients diagnosed with or suspected of having IgE-dependent hen's egg allergy? A systematic review	5
Efficacy, safety, and parental anxiety in a randomized trial of two dietary instruction methods for children with suspected hen's egg allergy	5
Differential role of mucus plugs in asthma: Effects of smoking and association with airway inflammation	4
Safety, efficacy, and pharmacokinetics of delgocitinib ointment in infants with atopic dermatitis: A phase 3, open-label, and long-term study	4
Pen a 1-specific IgE does not improve the accuracy of a shrimp allergy diagnosis among Japanese children due to cross-reactivity with Der p 10	4
Plasma miR223 is a possible biomarker for diagnosing patients with severe atopic dermatitis	4
Therapeutic monoclonal antibodies with a focus on hereditary angioedema	4
Summary of the current status of clinically diagnosed cases of Schnitzler syndrome in Japan	4
Association between house renovation during pregnancy and wheezing in the first year of life: The Japan environment and children's study	4
Association of longitudinal changes in quality of life with comorbidities and exacerbations in patients with severe asthma	4
Alarmins/stressorins and immune dysregulation in intractable skin disorders	4
Development of hypertriglyceridemia due to GPIHBP1 autoantibodies prior to clinical diagnosis of systemic lupus erythematosus in a 14-year-old girl	4
A phase 3, randomized, double-blind, clinical study to evaluate the long-term safety and efficacy of gefapixant in Japanese adult participants with refractory or unexplained chronic cough	4
Singlet oxygen -derived nerve growth factor exacerbates airway hyperresponsiveness in a mouse model of asthma with mixed inflammation	4
Latent 1,3-β-D-glucan acts as an adjuvant for allergen-specific IgE production induced by Japanese cedar pollen exposure	4
Clinical and histological characterization of transient dermal pain triggered by sweating stimuli	4
Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath	4
The prevalence of oral symptoms caused by Rosaceae fruits and soybean consumption in children; a Japanese population-based survey	4
Serum level of hemokinin-1 is significantly lower in patients with chronic spontaneous urticaria than in healthy subjects	4
Similarities and differences in autoinflammatory diseases with urticarial rash, cryopyrin-associated periodic syndrome and Schnitzler syndrome	4
Tolerability and safety of a new elimination diet for pediatric eosinophilic gastritis and duodenitis	4
Blood eosinophil count variability in chronic obstructive pulmonary disease and severe asthma	4
Association between the NOS2 pentanucleotide repeat polymorphism and risk of postoperative recurrence of chronic rhinosinusitis with nasal polyps in a Japanese population	4
Is oral food challenge test useful for avoiding complete elimination of cow's milk in Japanese patients with or suspected of having IgE-dependent cow's milk allergy?	4
Successful concomitant therapy with mepolizumab and dupilumab for atypical eosinophilic granulomatosis with polyangiitis	4
Comparison of clinical characteristics of the nasal manifestations of eosinophilic granulomatosis with polyangiitis (EGPA) and eosinophilic chronic rhinosinusitis (ECRS)	4
Diagnosis of non-immediate hypersensitivity to amoxicillin in children by skin test and drug provocation tests: A retrospective case-series study	4
Effect of gut microbial composition and diversity on major inhaled allergen sensitization and onset of allergic rhinitis	4
Crossing the valley of death: Toward translational research regarding ILC2	4
Efficacy and safety of tezepelumab in patients recruited in Japan who participated in the phase 3 NAVIGATOR study	4
Factors associated with the development of oral allergy syndrome: A retrospective questionnaire survey of Japanese university students	3
High prevalence of epilepsy in HAE with normal C1–INH	3
Effectiveness and safety of subcutaneous immunotherapy with standardized house dust mite extract for patients under the age of 5 years: A prospective cohort study	3
Novel inhibitors of histamine-releasing factor suppress food allergy in a murine model	3
Effect of endoscopic sinus surgery for chronic rhinosinusitis on the state of coexisting asthma	3
Characteristics of Japanese cypress pollen-induced allergic rhinitis by environmental challenge chamber	3
Analysis of drug-induced anaphylaxis cases using the Japanese Adverse Drug Event Report (JADER) database – secondary publication	3
A case of zonisamide-induced toxic epidermal necrolysis with acute respiratory failure	3
Isolation and characterization of the major centipede allergen Sco m 5 from Scolopendra subspinipes mutilans	3
The A118G single-nucleotide polymorphism in OPRM1 is a risk factor for asthma severity	3
M2 macrophage polarization in chronic spontaneous urticaria refractory to antihistamine treatment	3
A novel detection method for cross-linking of IgE-receptors by autoantibodies in chronic spontaneous urticaria	3
Calcium ionophore-activated platelets induce eosinophil extracellular trap formation	3
Three cases of diffuse panbronchiolitis in children with a past history of difficult-to-treat bronchial asthma: A case report from a single medical facility	3
Focal eosinophilic myositis with Charcot-Leyden crystal formation	3
Respiratory complications of Stevens-Johnson syndrome (SJS): 3 cases of SJS-induced obstructive bronchiolitis	3
The relationship between the development of erythroderma in patients with atopic dermatitis and the avoidance of anti-inflammatory topical drugs	3
IL-33-induced keratoconjunctivitis is mediated by group 2 innate lymphoid cells in mice	3
Single-cell RNA sequencing of peripheral blood mononuclear cells from Kimura disease patient successfully treated with dupilumab	3
Chitin induces steroid-resistant airway inflammation and airway hyperresponsiveness in mice	3
Wheezing trajectories from childhood to adulthood in a population-based cohort	3
A 60-minute dosing interval is safer than a 30- or 40-minute interval in oral food challenge	3
Successful management of eosinophilic chronic rhinosinusitis complicated by severe asthma using dupilumab, following negative initial results with benralizumab	3
Diagnostic utility of the basophil activation test in natto-induced hypersensitivity	3
Investigating Japanese cedar pollen-induced allergic rhinitis and related terms using Google Trends	3
Hypersensitivity to mosquito bites: A versatile Epstein–Barr virus disease with allergy, inflammation, and malignancy	3
Mapping naso-ocular symptom scores to EQ-5D-5L utility values in Japanese cedar pollinosis	3
Distinct subsets of innate lymphoid cells in nasal polyp	3
A case of hen's egg-dependent exercise-induced immediate-type allergy	3
Protease-digested egg-white products induce oral tolerance in mice but elicit little IgE production upon epicutaneous exposure	3
Low serum soluble ST2 level in early childhood is associated with the risk for asthma at 7 years of age	3
Contribution of monocyte and macrophage extracellular traps to neutrophilic airway inflammation in severe asthma	3
The clinical cross-reactivity and immunological cross-antigenicity of wheat and barley	3
Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma	3
Radiological significance of mediastinal lymphadenopathy in eosinophilic granulomatosis with polyangiitis	3
Real-world clinical practices for spontaneous urticaria and angioedema in Japan: A nation-wide cross-sectional web questionnaire survey	3
Executive summary: Japanese pediatric guideline for the treatment and management of asthma (JPGL) 2020	3
Corrigendum to “The multiple functions and subpopulations of eosinophils in tissues under steady-state and pathological conditions” [Allergol Int 70 (2021) 9–18]	3
Pretreatment circulating MAIT cells, neutrophils, and periostin predicted the real-world response after 1-year mepolizumab treatment in asthmatics	3