OOIR: Observatory of International Research

Papers

(The TQCC of Allergology International is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
A systematic review and meta-analysis of macrolides in the management of adult patients with asthma	139
Efficacy and safety of systemic targeted therapies for atopic dermatitis in children: A systematic review and meta-analysis	113
The relationship of polyunsaturated and monounsaturated fatty acids intake and serum concentrations on inhalant allergen sensitization and allergic rhinitis development	97
Validation of asthma discrimination criteria using health insurance claims data in Japan: Additional proposals for more specific criteria	74
Nailfold capillaroscopic abnormalities in angioedema with eosinophilia	71
Chitin induces steroid-resistant airway inflammation and airway hyperresponsiveness in mice	71
Sensitization to macadamia 7S globulin amino-terminus with clinical relevance in Japanese children with macadamia nut allergy	56
Efficacy and safety of dupilumab with concomitant topical corticosteroids in Japanese pediatric patients with moderate-to-severe atopic dermatitis: A randomized, double-blind, placebo-controlled phase	53
Small airway dysfunction in asthma based on oscillometry	51
Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma	45
Individual multidisciplinary clinical phenotypes of nasal and ocular symptoms in hay fever: Crowdsourced cross-sectional study using AllerSearch	43
Cluster analysis of phenotypes, job exposure, and inflammatory patterns in elderly and nonelderly asthma patients	41
S100A8 enhances IL-1β production from nasal epithelial cells in eosinophilic chronic rhinosinusitis	37
Association of walnut proteins in household dust with household walnut consumption and Jug r 1 sensitization	33
Cross-antigen analysis for allergies to multiple legumes (azuki beans, runner beans, white pea beans)	33
Assessment of serum periostin level as a predictor of requirement for intensive treatment for type-2 inflammation in asthmatics in future: A follow-up study of the KiHAC cohort	32
Potential determinants of T helper 2 markers and their distribution in school-aged children	32
Celecoxib induced respiratory symptoms without urinary LTE 4 increase in a patient with AERD	30
Airway epithelial STAT3 inhibits allergic inflammation via upregulation of stearoyl-CoA desaturase 1	29
A phase 3, randomized, double-blind, clinical study to evaluate the long-term safety and efficacy of gefapixant in Japanese adult participants with refractory or unexplained chronic cough	28
Periostin is an aggravating factor and predictive biomarker of eosinophilic chronic rhinosinusitis	28
CYP27A1-27-hydroxycholesterol axis in the respiratory system contributes to house dust mite-induced allergic airway inflammation	25
Blood eosinophil count variability in chronic obstructive pulmonary disease and severe asthma	24
LncRNA FAM239A modulates T helper cell responses via tyrosine phosphatase SHP2 in allergic rhinitis	23
Current perspective on allergen immunotherapy for food allergies	23

Effects of raw seafood on the risk of hypersensitivity reaction recurrence in patients with an Anisakis allergy: A retrospective observational study in Japan	23
Efficacy and safety of tezepelumab in patients recruited in Japan who participated in the phase 3 NAVIGATOR study	20
In vitro cross-reactivity between hen's egg and quail's egg in children with hen's egg allergy	19
Age-related differences in olfactory profiles and surgical outcomes in eosinophilic chronic rhinosinusitis	19
Regulation of the IgE response by T follicular regulatory cells	19
T follicular helper and memory B cells in IgE recall responses	18
Chronic urticaria and the pathogenic role of mast cells	18
T follicular helper cells and IgE	18
Control of immunity and allergy by steroid hormones	18
A 60-minute dosing interval is safer than a 30- or 40-minute interval in oral food challenge	18
Safety of local nasal immunotherapy using hypoallergenic birch pollen ointment in patients with pollen-food allergy syndrome: A preliminary study of five cases	17
Hyper-IgE syndrome, 2021 update	17
Questionnaire survey among ophthalmic allergists on dupilumab-associated ocular surface disease in Japan	17
Efficacy of dupilumab for airway hypersecretion and airway wall thickening in patients with moderate-to-severe asthma: A prospective, observational study	17
Group 2 innate lymphoid cells in human asthma	17
Similarities and differences in autoinflammatory diseases with urticarial rash, cryopyrin-associated periodic syndrome and Schnitzler syndrome	16
Elevated MS4A2 and IgE interaction in nasal polyps contributing to poor postoperative prognosis in patients with eosinophilic chronic rhinosinusitis	16
Cytokine profile of the stratum corneum in atopic dermatitis lesions differs between the face and the trunk	16
Neurodevelopment at 6 years of age in children with atopic dermatitis	16
Association of Japanese cedar pollen sensitization in children with Dermatophagoides pteronyssinus sensitization and maternal sensitization: Insights from the Yamanashi adjunct study within the Japan	16
Three-year prognoses after low-dose oral food challenge for cow's milk	15
Investigator-initiated, multi-center, single-arm, open-label study of the effectiveness of canakinumab in Japanese patients with Schnitzler syndrome	15
Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses	15
Multiple at-risk groups have lower lung function during the grass pollen season	14
Treatments of refractory eosinophilic lung diseases with biologics	14
Role of basal cells in nasal polyp epithelium in the pathophysiology of eosinophilic chronic rhinosinusitis (eCRS)	14
Non-IgE-mediated food allergy: Where are we now?	14
Safety, efficacy, and pharmacokinetics of delgocitinib ointment in infants with atopic dermatitis: A phase 3, open-label, and long-term study	14
Valuable lessons from analyses of common signs and symptoms in rare diseases	13
Efficacy of a house dust mite sublingual immunotherapy tablet as add-on dupilumab in asthma with rhinitis	13
The latest findings on ILC2s, from bench to bedside	13
Clinical and histological characterization of transient dermal pain triggered by sweating stimuli	13
Rapid progress in molecular targeted therapy for allergic diseases	13
Fasting-associated urticaria and/or anaphylaxis: A case report	12
Nonepisodic angioedema with eosinophilia during sublingual immunotherapy with house dust mite extract	12
Analysis of drug-induced anaphylaxis cases using the Japanese Adverse Drug Event Report (JADER) database – secondary publication	12
Poorly controlled asthma – Easy wins and future prospects for addressing fungal allergy	11
Is oral food challenge useful to avoid complete elimination in Japanese patients diagnosed with or suspected of having IgE-dependent hen's egg allergy? A systematic review	11
Allergic bronchopulmonary mycosis associated with a novel pathogen: Bjerkandera adusta	11
A diagnostic score for eosinophilic granulomatosis with polyangiitis among eosinophilic disorders	10
Reducing the solubility of the major birch pollen allergen Bet v 1 by particle-loading mitigates Th2 responses	10
Relationship between Aspergillus and asthma	10
Characteristics of food protein-induced enterocolitis syndrome with metabolic acidosis: A case–control study	10
Overviewing allergy epidemiology in Japan - Findings from birth cohorts (JECS and T-Child study)	10
IL-33-induced keratoconjunctivitis is mediated by group 2 innate lymphoid cells in mice	10
Genomic analysis reveals novel allergens of Blomia tropicalis	10
Antigen analysis of patients with gastrointestinal symptoms resulting from immediate allergic reactions to mushrooms	10
Mucus plugs in severe asthma and related airway diseases	10
A clinical and canine experimental study in small-airway response to bronchial thermoplasty: Role of the neuronal effect	10
Sub-pollen in platelet products: A potential cause of allergic transfusion reactions	10

Meropenem allergy testing performed at the bedside of hospitalized patients labelled with a penicillin allergy	10
Advantage of spirometry over oscillometry to detect dupilumab's effect on small airway dysfunction	10
Efficacy of sequential fecal-marker examination for evaluating gastrointestinal inflammation in solid food protein-induced enterocolitis syndrome	10
Contribution of monocyte and macrophage extracellular traps to neutrophilic airway inflammation in severe asthma	10
Potential of MAIT cells to modulate asthma	9
Executive summary: Japanese guidelines for allergic rhinitis 2020	9
Overweight improves long-term survival in Japanese patients with asthma	9
Management of severe asthma during the COVID-19 pandemic: A retrospective study using a Japanese database	9
Alarmins/stressorins and immune dysregulation in intractable skin disorders	9
Gut microbiota and allergic diseases in children	9
Local nasal immunotherapy with birch pollen-galactomannan conjugate-containing ointment in mice and humans	9
Exacerbating factors and disease burden in patients with atopic dermatitis	9
Prevention of IL-6 signaling ameliorates toluene diisocyanate-induced steroid-resistant asthma	9
ORMDL3/GSDMB genotype is associated with distinct phenotypes of adult asthma	9
Fluctuations of aeroallergen-specific immunoglobulins and children's allergic profiles: Japan Environment & Children's Study of a pilot cohort	8
Effects of subcutaneous allergen immunotherapy on non-targeted allergen-induced immune responses	8
Biochemistry, molecular genetics, and clinical aspects of hereditary angioedema with and without C1 inhibitor deficiency	8
Analysis of the relationship between comorbid obstructive sleep apnea and clinical outcomes in patients with asthma in Japan	8
Mortality and risk factors on admission in toxic epidermal necrolysis: A cohort study of 59 patients	8
Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents	8
Impact of obesity in asthma: Possible future therapies	8
Insights from the COCOA birth cohort: The origins of childhood allergic diseases and future perspectives	8
Periostin upregulates the effector functions of neutrophils	8
Association between house renovation during pregnancy and wheezing in the first year of life: The Japan environment and children's study	8
The clinical features of intractable allergic rhinitis based on a questionnaire administered to clinicians	8
Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans	8