Neurogastroenterology and Motility

Article	Citations
Tamoxifen administration alters gastrointestinal motility in mice	51
Mucosal eosinophils, mast cells, and intraepithelial lymphocytes in youth with rumination syndrome	51
The visceral sensitivity index: A novel tool for measuring GI‐symptom‐specific anxiety in inflammatory bowel disease	48
Effect of intracolonic volume on gastric sensory‐motor responses in constipation‐predominant irritable bowel syndrome	44
Retraction: PKC‐delta and PKD activate MAPK signal pathway in mechano‐transcription of colonic smooth muscle cells	41
Chagas' disease achalasia may represent a sub‐group of type 2 achalasia without focal elevated pressures	41
Front Cover	40
Placebo effects in functional dyspepsia: Causes and implications for clinical trials	40
Letter in response to Black et al. (2020): Authors’ Reply	40
Issue Information	40
Clinical Characteristics and Outcomes of Patients With Rome IV Functional Dyspepsia Who Consume Opioids: A Real‐World Study	40
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Achalasia: Current therapeutic options	33
Natural history and impact of irritable bowel syndrome‐type symptoms in inflammatory bowel disease during 12 months of longitudinal follow‐up	32
Prescription pain medications for disorders of gut–brain interaction: Comparing usage patterns with clinical practice recommendations	31
TypeIIachalasia with focal elevated pressures: A distinct manometric and clinicalsub‐group	29
Issue Information	29
The integrated relaxation pressure may not be an appropriate gold standard for deglutitive relaxation due to reliance on a single intragastric reference sensor	29
Effect of Thickened Fluids on Swallowing Function in Oropharyngeal Dysphagia: Impact of Shear Rheology and Disorder Subtype	27
The epidemiology and impact of disorders of gut–brain interaction in Canada: Results from the Rome Foundation Global Epidemiologic Study	26
Assessing the diagnostic yield of achalasia using provocative testing in high‐resolution esophageal manometry: Serial diagnostic study	26
High amplitude propagated contractions with glycerin versus bisacodyl: Are we comparing apples to oranges?	25

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Gastric electrical stimulation is safe during pregnancy and delivery: Results from a French cohort	25
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Maximum lingual pressure impacts both swallowing safety and efficiency in individuals with amyotrophic lateral sclerosis	24
Effect of high altitude on human postprandial 13C‐octanoate metabolism, intermediary metabolites, gastrointestinal peptides, and visceral perception	23
Issue Information	22
Introducing the Journal's new Editors' team	22
Improved diagnosis of reflux hypersensitivity	22
Factors associated with hiatal hernia in neurologically impaired children	21
COVID‐19–related personal product shortages are associated with psychological distress in people living with gastrointestinal disorders: A cross‐sectional survey	21
Optimizing educational methods for the low FODMAP diet in disorders of gut–brain interaction: A feasibility randomized controlled trial	21
Parkinson's disease is associated with low striated esophagus contractility potentially contributing to the development of dysphagia	20
Virtual Tai Chi program for patients with irritable bowel syndrome with constipation: Proof‐of‐concept feasibility trial	19
He who controls Clostridia and Bacteroidia controls the gut microbiome: The concept of targeted probiotics to restore the balance of keystone taxa in irritable bowel syndrome	19
Sacral neuromodulation in children and adolescents with defecation disorders	18
Characterization of idiopathic chronic diarrhea and associated intestinal inflammation and preliminary observations of effects of vagal nerve stimulation in a non‐human primate	18
The rise and fall of esophageal function tests. Comment on: Taft et al. Initial assessment of medical post‐traumatic stress among patients with chronic esophageal diseases	18
Diagnostic yield of colonoscopy for organic disease in irritable bowel syndrome and its risk factors: A meta‐analysis	17
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Regulation of the central amygdala on intestinal motility and behavior via the lateral hypothalamus in irritable bowel syndrome model mice	16
Abstracts of the 19th American Neurogastroenterology and Motility Society Annual Scientific Meeting August 13–15, 2021 Boston, Massachusetts, USA	16
The impact of primary peristalsis, contractile reserve, and secondary peristalsis on esophageal clearance measured by timed barium esophagogram	16
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Issue Information	15
Cover Image	15
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Abstract	15
Author Index	15
AUTHOR INDEX	15
Oral and parenteral anti‐neuropathic agents for the management of pain and discomfort in irritable bowel syndrome: A systematic review and meta‐analysis	14
Gastric sensorimotor function and its clinical measurement	14
Reply: The key to success: Targeting enzymes to their dietary counterpart	14
Peripherally‐active mu‐opioid receptor antagonists for constipation in critically ill patients receiving opioids: A case‐series and a systematic review and meta‐analysis of the literature	14
Enhanced neuron–glia network in the submucosa and increased neuron outgrowth into the mucosa are associated with distinctive expressions of neuronal factors in the colon of rat IBS model	13
Diagnostic yield of left‐sided colonic manometry in identifying colonic dysmotility in pediatric patients	13
Association of adverse childhood experiences with irritable bowel syndrome in Mexican adults: A cross‐sectional study	13
Latent profile analysis reveals the central role of psychological symptoms in driving disease severity in chronic constipation	13
Prevalence and impact of Rome IV versus Rome III irritable bowel syndrome in patients with inflammatory bowel disease	13
Differences in provider recommendations for Black/African American and White patients with irritable bowel syndrome	13
Should we have to include transcutaneous neuromodulation in the therapeutic GERD armamentarium?	13
Optimizing techniques for measuring anal resting and squeeze pressures with high‐resolution manometry	13
Allergen‐free extracts from birch, ragweed, and hazel pollen activate human and guinea‐pig submucous and spinal sensory neurons	13
Radiopaque marker colonic transit study in the pediatric population BSPGHAN Motility Working Group consensus statement	13
Placebo response to sham electroacupuncture in patients with chronic functional constipation: A secondary analysis	13
Episode‐level reflux characteristics: How experienced reviewers differentiate true reflux from artifact on pH‐impedance studies	12
Association between dietary factors, symptoms, and psychological factors in adults with dyspepsia: A cross‐sectional study	12
The key to success: Targeting enzymes to their dietary counterpart	12
Issue Information	12
Optimizing nutrition in pediatric intestinal pseudo‐obstruction syndrome	12
Issue Information	12

Association between childhood constipation and exposure to stressful life events: a systematic review	12
Efficacy and safety of vibegron for the treatment of irritable bowel syndrome in women: Results of a randomized, double‐blind, placebo‐controlled phase 2 trial	12
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Towards a more precise classification of esophageal motility disorders in patients with systemic sclerosis	12
The effect of combined oral contraceptives and Nexplanon on gastroesophageal reflux disease in premenopausal women: A nationwide database analysis	12
Effects of dexmedetomidine on pharyngeal swallowing and esophageal motility—A double‐blind randomized cross‐over study in healthy volunteers	12
Antroduodenal motility recording identifies characteristic patterns in gastroparesis related to underlying etiology	12
Author response to letter to the editor	12
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Secondary peristalsis and esophagogastric junction distensibility in symptomatic post‐fundoplication patients	11
Pharmacogenomic testing for CYP2C19 and CYP2D6 in cyclic vomiting syndrome	11
Mast cell mediation of visceral sensation and permeability in irritable bowel syndrome	11
Association between dietary protein intake and constipation: Data from the National Health and nutrition examination survey 2005–2010	11
Perspectives, experiences, and concerns with cyclical vomiting syndrome: Insights from online targeted‐disease forums	11
Esophageal mucosal sensory nerves and potential mechanoreceptors in patients with ineffective esophageal motility	11
Barostat or syringe‐assisted sensory biofeedback training for constipation with rectal hyposensitivity: A randomized controlled trial	11
Identifying hiatal hernia with impedance planimetry during esophageal distension testing	11
A multidisciplinary approach to identifying and managing heterotopic gastric inlet patches	11
Relationship between symptoms during a gastric emptying study, daily symptoms and quality of life in patients with diabetes mellitus	11
Laxative and purgative actions of phytoactive compounds from beetroot juice against loperamide‐induced constipation, oxidative stress, and inflammation in rats	11
The antroduodenal transition time is prolonged in adults with type 1 diabetes	11
L‐glutathione 1% promotes neuroprotection of nitrergic neurons and reduces the oxidative stress in the jejunum of rats with Walker‐256‐bearing tumor	10
Normal Anal Sensibility in Patients Born With Anorectal Malformations	10
Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction	10
Effect of liquid and solid test meals on symptoms and gastric myoelectrical activity in patients with gastroparesis and functional dyspepsia	10
Issue Information	10
Treatment for chronic idiopathic constipation: Use and satisfaction from a nationwide survey of US participants	10
Fecal luminal factors from patients with irritable bowel syndrome induce distinct gene expression of colonoids	10
Association between post‐reflux swallow‐induced peristaltic wave index and esophageal mucosal integrity in patients with GERD symptoms	10
The Milan Score Predicts Objective Gastroesophageal Reflux Disease in Patients With Type 2 Esophagogastric Junction	10
The clinical application value of salivary pepsin in the diagnosis of gastroesophageal reflux diseases	10
Effects of menthol on esophageal motility in humans: Studies using high‐resolution manometry	10
Pediatric Rome IV diagnosis agreement is greater than agreement on diagnostic testing	10
Clinical characteristics and long‐term outcomes in patients with cyclic vomiting syndrome: A 15‐year experience at a tertiary referral center	10
Latent class analysis does not support the existence of Rome IV functional bowel disorders as discrete entities	10
Magnetic Resonance Imaging of Gastric Motility in Conscious Rats	10
Effect of hiatus hernia on reflux patterns and mucosal integrity in patients with non‐erosive reflux disease	10
The role of microbiota and its modulation in colonic diverticular disease	10
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Enteric neuroprotection—A matter of balancing redox potentials, limiting inflammation, and boosting resilience	10
Symptom bothersomeness and life interference support Rome clinical criteria as clinically relevant indicators of DGBI	9
High‐resolution in vivo monophasic gastric slow waves to quantify activation and recovery profiles	9
Reliability of pediatric Rome IV criteria for the diagnosis of disorders of gut–brain interaction	9
Clinical efficacy and mechanism of transcutaneous neuromodulation on ineffective esophageal motility in patients with gastroesophageal reflux disease	9
Body Surface Gastric Mapping Delineates Specific Patient Phenotypes in Adolescents With Functional Dyspepsia and Gastroparesis	9
Dysphagia lusoria: utility of high‐resolution impedance manometry to identify true disease	9
The impact of transcutaneous electrical acustimulation (TEA) on rectal distension‐induced pain in patients with irritable bowel syndrome (IBS)—A study to determine the optimal	9
Quantification of gastric emptying with magnetic resonance imaging in healthy volunteers: A systematic review	9
Post‐operative colonic manometry in children with anorectal malformations: A systematic review	9
The patient with obstructed defecatory symptoms: Management differs considerably between physicians and surgeons	9
Greater intolerance to uncertainty predicts poorer quality of life in adults with cyclic vomiting syndrome	9
Short‐ and long‐term reproducibility of body surface gastric mapping using the Gastric Alimetry® system	9
Discriminating “impaired” from “disordered” contractile response on FLIP panometry by utilizing pressure measurement	9
Visceral hypersensitivity induced by mild traumatic brain injury via the corticotropin‐releasing hormone receptor: An animal model	8
Self‐reported gastrointestinal disorders among veterans with gulf war illness with and without posttraumatic stress disorder	8
Authors' Response to: Do not forget recommendations for transition to the adult world in esophageal atresia patients!	8
Fifteen‐year symptomatic outcome of patients with nonactionable motor findings on high‐resolution manometry	8
Erratum	8
Do antro‐duodenal manometry parameters predict clinical response after gastric peroral endoscopic pyloromyotomy in refractory gastroparesis?	8
Correlation of deglutitive striated esophagus motor function and pharyngeal phase swallowing biomechanical events	8
Prevalence and impact of disorders of Gut–Brain interaction in Sweden	8
Rikkunshito improves anorexia through ghrelin‐ and orexin‐dependent activation of the brain hypothalamus and mesolimbic dopaminergic pathway in rats	8
Intra‐ and interindividual variability in fasted gastric content volume	8
Fecal bacteria and short‐chain fatty acids in irritable bowel syndrome: Relations to subtype	8
Plecanatide for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation: Post hoc analyses of placebo‐controlled trials in adults with severe constipation	8
Transvaginal rectocoele repair for the surgical treatment of a “symptomatic” rectocoele when conservative measures fail: A 12 year experience of 215 patients	8
The ghrelin agonist, HM01 activates central vagal and enteric cholinergic neurons and reverses gastric inflammatory and ileus responses in rats	8
High‐resolution versus conventional manometry for the diagnosis of small bowel motor dysfunction	8
Comparison of measurement of integrated relaxation pressure by esophageal manometry with analysis of swallowing sounds with artificial intelligence in patients with achalasia	8
Activation of CRF1 receptors expressed in brainstem autonomic nuclei stimulates colonic enteric neurons and secreto‐motor function in male rats	8
Milk coagulation and gastric emptying in women experiencing gastrointestinal symptoms after ingestion of cow's milk	8
Effect of Iberogast (STW5) on tolerance to colonic gas in patients with irritable bowel syndrome: A randomized, double‐blind, placebo control clinical trial	8
Somatic, emotional, and gastrointestinal symptom severity are increased among children and adolescents with COVID‐19	8
Positive psychological well‐being: A novel concept for improving symptoms, quality of life, and health behaviors in irritable bowel syndrome	8
Autoimmune and viral risk factors are associated with achalasia: A case‐control study	8
Author Index	8
Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: Two prospective longitudinal population‐based studies	8
Genome‐Wide DNA Methylation Identifies Potential Disease‐Specific Biomarkers and Pathophysiologic Mechanisms in Irritable Bowel Syndrome, Inflammatory Bowel Disease, and Celiac Disease	7
Cyclic vomiting syndrome: A patient/parent perspective	7
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Authors' Reply to Letter—Role of Prokinetics in Ineffective Esophageal Motility: A Call for Broader Consideration and Future Innovations	7
Esophagogastric junction outflow obstruction	7
A Heavy Feeling in the Stomach: Neural Correlates of Anxiety in Crohn's Disease	7
Effects of pharmacological agents for neurogenic oropharyngeal dysphagia: A systematic review and meta‐analysis	7
Chronic jetlag reprograms gene expression in the colonic smooth muscle layer inducing diurnal rhythmicity in the effect of bile acids on colonic contractility	7
Cannabis use patterns and association with hyperemesis: A comprehensive review	7
Could the Therapeutic Effect of Physical Activity on Irritable Bowel Syndrome Be Mediated Through Changes to the Gut Microbiome? A Narrative and Hypothesis Generating Review	7
Trends in Prevalence of Rome IV Disorders of Gut‐Brain Interaction During the COVID‐19 Pandemic: Results From a Nationally Representative Sample of Over 160,000 People in the US	7
Standardized system and App for continuous patient symptom logging in gastroduodenal disorders: Design, implementation, and validation	7
Functional and anatomical gastric regions and their relations to motility control	7
Gastrointestinal Cognition: Pain Catastrophizing in Irritable Bowel Syndrome, a Cross‐Sectional Study in Mexico	7
Clinical associations of functional dyspepsia with gastric dysrhythmia on electrogastrography: A comprehensive systematic review and meta‐analysis	7
Sex Differences, Menses‐Related Symptoms and Menopause in Disorders of Gut–Brain Interaction	7
Repetitive antegrade contractions on high‐resolution manometry: A physiologic pattern related to sustained esophageal distention in Abelchia	7
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin‐releasing hormone receptor 2	7
Systematic Review: Integrated Models of Care for Managing Irritable Bowel Syndrome	7
Magnetic resonance imaging as a non‐invasive tool to assess gastric emptying in mice	7
How to effectively use and interpret the barium swallow: Current role in esophageal dysphagia	7
Epigastric symptom response to low FODMAP dietary advice compared with standard dietetic advice in individuals with functional dyspepsia	7
Extensive scintigraphic gastric motor function testing with concurrent symptom recording predicts prospectively measured daily dyspeptic symptoms	6
Targeting the pylorus in gastroparesis: From physiology to endoscopic pyloromyotomy	6
Appropriate use of p‐values	6
Gastrointestinal Dysfunction and Low‐Grade Inflammation Associate With Enteric Neuronal Amyloid‐β in a Model for Amyloid Pathology	6
Prospective Evaluation of Autonomic Function and Intestinal Blood Flow in Health and Irritable Bowel Syndrome Shows Differences Limited to Patients With Constipation Predominance	6
Decoding Gastric Reflexes: The Role of Mechanosensitive Enteric Neurons in Stomach Motility	6
Dumping syndrome: Update on pathophysiology, diagnosis, and management	6
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Tolerability, gastric emptying patterns, and symptoms during the Nottingham Test Meal in 330 secondary care non‐diabetic dyspeptic patients	6
Relationships among symptoms of gastroparesis to those of avoidant/restrictive food intake disorder in patients with gastroparesis	6
Evaluation of a Novel Smart Capsule Bacterial Detection System Device for Diagnosis of Small Intestinal Bacterial Overgrowth	6
Gastrointestinal diagnoses in patients with eating disorders: A retrospective cohort study 2010–2020	6
Isoflurane anesthesia suppresses gastric myoelectric power in the ferret	6
Nasopharyngeal airway assistance improves esophageal intubation rates of high‐resolution esophageal manometry catheters	6
Proximal esophageal impedance baseline increases the yield of impedance‐pH and is associated with response to PPIs in chronic cough patients	6
Is global score better than a single histological parameter for assessing microscopic esophagitis?	6
Exploring the Antiemetic Potential of Caffeic Acid: A Combined In Vivo and Computational Approach	6
Issue Information	6
Characterization of Anal Slow Waves and Ultraslow Waves in Patients With Constipation and Healthy Subjects	6
A Software Framework for the Functional Lumen Imaging Probe—Mechanics (MechView)	6
Issue Information	6
The Clinical value of brain‐gut behavioral therapies for functional esophageal disorders and symptoms	6
Direct Stimulation of Gastric Smooth Muscle Cells via Gq Proteins With Light	6
Examining the optimal cutoff values of HADS, PHQ‐9 and GAD‐7 as screening instruments for depression and anxiety in irritable bowel syndrome	6
Acute care of cyclic vomiting syndrome and cannabinoid hyperemesis syndrome in the home and emergency department	6
Central mechanisms of emesis: A role for GDF15	6
Impact of anesthetics on pyloric characteristics measured using the EndoFLIP® system in patients with gastroparesis	6
Spastic secondary contractile patterns identified by FLIP panometry in symptomatic patients with unremarkable high‐resolution manometry	6
Evaluation of bidirectional gut‐brain axis and anorectal function in Parkinson's disease with constipation	6
Validation of the Dynamic Imaging Grade of Swallowing Toxicity for Amyotrophic Lateral Sclerosis	6
Symptom Patterns in Adults With Cyclic Vomiting Syndrome: A 6‐Month Prospective Observational Study	6
Advancements in Our Understanding and Management of Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis	6
Treatment outcomes in patients with globus: A randomized control trial of psychoeducation, neuromodulators, and proton pump inhibitors	6
Role of inflammation in pediatric irritable bowel syndrome	6
When to p and when not to p	6
The Rome Foundation Global Epidemiology study: Research opportunities national and worldwide	6
Assessing the Clinical Value of 2‐h Versus 4‐h Gastric Emptying Scintigraphy in Pediatrics: A Systematic Review and Meta‐Analysis	6
Because secondary intestinal pseudo‐obstruction is potentially treatable, its etiology needs to be clarified	5
Prokinetics‐safety and efficacy: The European Society of Neurogastroenterology and Motility/The American Neurogastroenterology and Motility Society expert review	5
The effect of sleep positional therapy on nocturnal gastroesophageal reflux measured by esophageal pH‐impedance monitoring	5
Cardiac autonomic regulation and joint hypermobility in adolescents with functional abdominal pain disorders	5
Role of stimulator of interferon genes (STING) in the enteric nervous system in health and disease	5
Prevalence and beverage‐related risk factors of gastroesophageal reflux disease: An original study in Chinese college freshmen, a systemic review and meta‐analysis	5
Automated extraction of anorectal pressures from high‐resolution manometry reports	5
Anxiety correlates with excessive air swallowing and PPI refractoriness in patients with concomitant symptoms of GERD and functional dyspepsia	5
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Comparison of the epidemiology of disorders of gut–brain interaction in four Latin American countries: Results of The Rome Foundation Global Epidemiology Study	5
Rectocele: Incidental or important? Observe or operate? Contemporary diagnosis and management in the multidisciplinary era	5
Issue Information	5
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In the memory of our following colleagues, and friends	5
Autoantigen characterization in the lower esophageal sphincter muscle of patients with achalasia	5
Lidocaine before esophageal manometry and ambulatory pH monitoring: A randomized controlled trial	5
Development and validation of an electronic version of Sydney Swallow Questionnaire	5
Age‐related differences of γ‐aminobutyric acid (GABA)ergic transmission in human colonic smooth muscle	5
News from the Editors	5
The clinical effect of benesco™ on reflux symptoms: A double‐blind randomized placebo‐controlled trial	5
Burden of illness and treatment attitudes among participants meeting Rome IV criteria for irritable bowel syndrome: A nationwide survey in the United States	5
Methodological considerations and prevalence trends in disorders of gut–brain interaction: Lessons from comparative studies	5
The epidemiology and burden of gastroparesis: Real‐world data from a large healthcare provider in Israel	5
High‐resolution impedance manometry characterizes the functional role of distal colonic motility in gas transit	5
Downregulation of BDNF–TrkB signaling may contribute to the colonic motility disorders in mice with streptozocin‐induced diabetes	5
Magnetic resonance imaging assessed enteric motility and luminal content analysis in patients with severe bloating and visible distension	5
Impact of Rome IV criteria on the prevalence of post‐infection irritable bowel syndrome	5
Issue Information	5
Liquid and solid gastric emptying and correlation with clinical characteristics in pediatric patients with dyspepsia	5
Feeding during the resting phase causes gastrointestinal tract dysfunction and desynchronization of metabolic and neuronal rhythms in rats	5
Identifying spastic variant of type II achalasia after treatment with high‐resolution manometry and FLIP Panometry	5
On‐therapy impedance‐pH monitoring can efficiently characterize PPI‐refractory GERD and support treatment escalation	5
Defecatory disorders in patients with type 1 diabetes and chronic constipation	5
Using a footstool does not aid simulated defecation in undifferentiated constipation: A randomized trial	5
First study to assess the reliability of commonly used pain scales in children with disorders of gut‐brain interaction	5
An investigation into the effect of nasogastric intubation on markers of autonomic nervous function	5
Multidisciplinary behavioral therapy reduces rumination	5