Cell Death and Differentiation

Article	Citations
HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2	853
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis	496
NKAP acts with HDAC3 to prevent R-loop associated genome instability	405
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development	329
Retraction Note to: Glucose-6-phosphate dehydrogenase plays a crucial role in protection from redox-stress-induced apoptosis	311
The Smad4-MYO18A-PP1A complex regulates β-catenin phosphorylation and pemigatinib resistance by inhibiting PAK1 in cholangiocarcinoma	274
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment	274
NAT10 regulates mitotic cell fate by acetylating Eg5 to control bipolar spindle assembly and chromosome segregation	238
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC progression by mediating HIF heterodimerization and histone trimethylation under a hypoxic microenvironment	236
Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease	232
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution	218
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling	196
PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions	178
Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt–β-catenin–STAT3 signaling	167
Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss	161
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response	156
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A	148
Long Covid: where we stand and challenges ahead	146
USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L1	145
Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease	136
The birth of death, 30 years ago	135
USP38 functions as an oncoprotein by downregulating the p53 pathway through deubiquitination and stabilization of MDM2	132
Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activato	130
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer	124
Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development	119

KRAS mutation increases histone H3 lysine 9 lactylation (H3K9la) to promote colorectal cancer progression by facilitating cholesterol transporter GRAMD1A expression	118
Disrupting CCDC137-mediated LZTS2 and β-TrCP interaction in the nucleus inhibits hepatocellular carcinoma development via β-catenin and AKT	117
Uridine 5’-monophosphate (UMP) synthesis connects nucleotide metabolism to programmed cell death in C. elegans	117
Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent	113
The bone–liver interaction modulates immune and hematopoietic function through Pinch-Cxcl12-Mbl2 pathway	112
Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics	109
A chromosome-coupled ubiquitin-proteasome pathway is required for meiotic surveillance	107
MLKL post-translational modifications: road signs to infection, inflammation and unknown destinations	106
USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins	105
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs	104
miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1	94
Targeting necroptosis prevents viral-induced lung damage	87
AF9 targets acetyl-modified STAT6 to diminish purine metabolism and accelerate cell apoptosis during metastasis	87
Correction: NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells	81
Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions	79
Aberrant activation of p53/p66Shc-mInsc axis increases asymmetric divisions and attenuates proliferation of aged mammary stem cells	76
Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1	76
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer	73
Sub-lethal signals in the mitochondrial apoptosis apparatus: pernicious by-product or physiological event?	71
The USP43/RNF2 axis negatively regulates antiviral innate immunity by promoting TBK1 ubiquitination and degradation	70
DDHD2, whose mutations cause spastic paraplegia type 54, enhances lipophagy via engaging ATG8 family proteins	70
CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity	69
Daniel Aberdam, the legacy of a mentor	69
Correction: The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis	67
Dying in self-defense: cell death signaling in animals and plants	66
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer	65
A viral interferon regulatory factor degrades RNA-binding protein hnRNP Q1 to enhance aerobic glycolysis via recruiting E3 ubiquitin ligase KLHL3 and decaying GDPD1 mRNA	64
Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer	63
TIN2 modulates FOXO1 mitochondrial shuttling to enhance oxidative stress-induced apoptosis in retinal pigment epithelium under hyperglycemia	62
Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress	61
SIRT5-mediated ME2 desuccinylation promotes cancer growth by enhancing mitochondrial respiration	61
Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor	59
Chromosomal 3p loss and 8q gain drive vasculogenic mimicry via HIF-2α and VE-cadherin activation in uveal melanoma	59
Targeting N-glycosylation of 4F2hc mediated by glycosyltransferase B3GNT3 sensitizes ferroptosis of pancreatic ductal adenocarcinoma	58
The multifaceted role of ferroptosis in liver disease	57
Crosstalk between GLTSCR1-deficient endothelial cells and tumour cells promotes colorectal cancer development by activating the Notch pathway	56
Correction to: Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc	54
A truncating variant of RAD51B associated with primary ovarian insufficiency provides insights into its meiotic and somatic functions	54
GSK3β mediates the spatiotemporal dynamics of NLRP3 inflammasome activation	53
Single cell-derived spheroids capture the self-renewing subpopulations of metastatic ovarian cancer	52
Decoding p53 tumor suppression: a crosstalk between genomic stability and epigenetic control?	52
SOCS2-enhanced ubiquitination of SLC7A11 promotes ferroptosis and radiosensitization in hepatocellular carcinoma	51
SPOP mutations promote p62/SQSTM1-dependent autophagy and Nrf2 activation in prostate cancer	51
Apoptotic priming is defined by the dynamic exchange of Bcl-2 proteins between mitochondria and cytosol	50
A novel feedback loop between DYRK2 and USP28 regulates cancer homeostasis and DNA damage signaling	50
Regulation of Semaphorin3A in the process of cutaneous wound healing	50
Deer antlers: the fastest growing tissue with least cancer occurrence	49
BAX and BAK dynamics control mitochondrial DNA release during apoptosis	49
Correction: Inhibition of ferroptosis counteracts the advanced maternal age-induced oocyte deterioration	48
Lymphoma cells lacking pro-apoptotic BAX are highly resistant to BH3-mimetics targeting pro-survival MCL-1 but retain sensitivity to conventional DNA-damaging drugs	48

Cell death in multiple sclerosis	48
Human skin specific long noncoding RNA HOXC13-AS regulates epidermal differentiation by interfering with Golgi-ER retrograde transport	48
The cGAS-Ku80 complex regulates the balance between two end joining subpathways	47
A novel HIF-2α targeted inhibitor suppresses hypoxia-induced breast cancer stemness via SOD2-mtROS-PDI/GPR78-UPRER axis	46
Extreme conservation of the poly-glutamine tract in huntingtin is related to neurodevelopmental functions: the “better” may become the “enemy of the good” in the course of evolution	46
Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries	46
ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression	46
Publisher Correction: Cell death as an architect of adult skin stem cell niches	45
Cell cycle regulation: p53-p21-RB signaling	45
Correction to: S100 family proteins are linked to organoid morphology and EMT in pancreatic cancer	44
CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death	44
CRL4B complex-mediated H2AK119 monoubiquitination restrains Th1 and Th2 cell differentiation	43
p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways	43
Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis	43
Non-coding small nucleolar RNA SNORD17 promotes the progression of hepatocellular carcinoma through a positive feedback loop upon p53 inactivation	43
Transcriptional regulation of autophagy and its implications in human disease	43
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility	42
TREM2 macrophage promotes cardiac repair in myocardial infarction by reprogramming metabolism via SLC25A53	42
The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities	42
E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson’s Disease model	42
Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation	41
SPY1 inhibits neuronal ferroptosis in amyotrophic lateral sclerosis by reducing lipid peroxidation through regulation of GCH1 and TFR1	41
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions	41
DEPTOR suppresses lymphomagenesis by promoting EGFR degradation via HUWE1 E3 ligase	41
A positive feedback loop between SERPINH1 and MMP-9/TGF-β1 promotes lung adenocarcinoma progression	40
SLC25A51 promotes tumor growth through sustaining mitochondria acetylation homeostasis and proline biogenesis	40
HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells	39
The PML1-WDR5 axis regulates H3K4me3 marks and promotes stemness of estrogen receptor-positive breast cancer	38
ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis	37
Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma	37
Cockayne syndrome mice reflect human kidney disease and are defective in de novo NAD biosynthesis	37
C9orf72 functions in the nucleus to regulate DNA damage repair	37
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity	37
Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state	36
Correction to: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development	36
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection	36
Mechanisms controlling plant proteases and their substrates	36
GCLC desuccinylation regulated by oxidative stress protects human cancer cells from ferroptosis	35
Hepatic factor MANF drives hepatocytes reprogramming by detaining cytosolic CK19 in intrahepatic cholangiocarcinoma	35
Atg7 autophagy-independent role on governing neural stem cell fate could be potentially applied for regenerative medicine	34
Cancer-intrinsic Cxcl5 orchestrates a global metabolic reprogramming for resistance to oxidative cell death in 3D	34
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis	33
SNORD88C guided 2′-O-methylation of 28S rRNA regulates SCD1 translation to inhibit autophagy and promote growth and metastasis in non-small cell lung cancer	33
Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation	33
RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria	33
Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak	33
RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation	33
Externalized phosphatidylinositides on apoptotic cells are eat-me signals recognized by CD14	33
E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB2	32
Correction: Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease	31
Telomerase deficiency and dysfunctional telomeres in the lung tumor microenvironment impair tumor progression in NSCLC mouse models and patient-derived xenografts	31
Correction: Global deletion of optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget’s disease	31
O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interaction	31
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies	31
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice	31
Sirtuin 4 activates autophagy and inhibits tumorigenesis by upregulating the p53 signaling pathway	31
Deubiquitinase USP7 stabilizes KDM5B and promotes tumor progression and cisplatin resistance in nasopharyngeal carcinoma through the ZBTB16/TOP2A axis	30
MARCH8/NSUN6/ROS-mediated DNA damage positive feedback loop regulates cisplatin resistance in osteosarcoma	30
Mutant p53 reactivation restricts the protumorigenic consequences of wild type p53 loss of heterozygosity in Li-Fraumeni syndrome patient-derived fibroblasts	30
A STING for necroptosis	30
GPX4-AUTAC induces ferroptosis in breast cancer by promoting the selective autophagic degradation of GPX4 mediated by TRAF6-p62	30
Correction to: M6A RNA methylation-mediated RMRP stability renders proliferation and progression of non-small cell lung cancer through regulating TGFBR1/SMAD2/SMAD3 pathway	30
The role(s) of NF-Y in development and differentiation	30
The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway	30
LUBAC enables tumor-promoting LTβ receptor signaling by activating canonical NF-κB	29
The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine	29
NLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development	29
Oxoglutarate dehydrogenase-like inhibits the progression of hepatocellular carcinoma by inducing DNA damage through non-canonical function	29
TRIM24-mediated K27-linked ubiquitination of ULK1 alleviates energy stress-induced autophagy and promote prostate cancer growth in the context of SPOP mutation	29
Extrinsic apoptosis and necroptosis in telencephalic development: a single-cell mass cytometry study	29
EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma	28
Correction to: Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas	28
A BAK subdomain that binds mitochondrial lipids selectively and releases cytochrome C	28
Ubiquitin ligase E3 HUWE1/MULE targets transferrin receptor for degradation and suppresses ferroptosis in acute liver injury	28
Correction: lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into th	27
Targeting KAT8 alleviates self-RNA-driven skin inflammation by modulating histone H4 lysine 16 acetylation in psoriasis	27
Exploring fructose metabolism as a potential therapeutic approach for pancreatic cancer	27
Exploring the future of research in the Tp53 field	27
Collagen I-DDR1 signaling promotes hepatocellular carcinoma cell stemness via Hippo signaling repression	27
Visualization of BOK pores independent of BAX and BAK reveals a similar mechanism with differing regulation	27

iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers	27
DJ-1 binds to Rubicon to Impair LC-3 Associated Phagocytosis	27
IKAROS: from chromatin organization to transcriptional elongation control	27
Transient targeting of BIM-dependent adaptive MCL1 preservation enhances tumor response to molecular therapeutics in non-small cell lung cancer	27
Lineage tracing of mutant granulosa cells reveals in vivo protective mechanisms that prevent granulosa cell tumorigenesis	26
Small extracellular vesicles delivering lncRNA WAC-AS1 aggravate renal allograft ischemia‒reperfusion injury by inducing ferroptosis propagation	26
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer	26
N6-Methyladenosine-modified circSAV1 triggers ferroptosis in COPD through recruiting YTHDF1 to facilitate the translation of IREB2	26
PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation	26
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4	26
Hypoxia-activated XBP1s recruits HDAC2-EZH2 to engage epigenetic suppression of ΔNp63α expression and promote breast cancer metastasis independent of HIF1α	26
Histone deacetylase 6 deacetylates and ubiquitinates ATG3 to regulate autophagy	26
Remembering foods and foes: emerging principles of transcriptional memory	25
Mitochondria in the line of fire	25
Anaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell growth	25
CSTF2-impeded innate αβ T cell infiltration and activation exacerbate immune evasion of pancreatic cancer	25
ZNF451 collaborates with RNF8 to regulate RNF168 localization and amplify ubiquitination signaling to promote DNA damage repair and regulate radiosensitivity	25
Collaborative orchestration of BH3-only proteins governs Bak/Bax-dependent hepatocyte apoptosis under antiapoptotic protein-deficiency in mice	25
METTL3 confers oxaliplatin resistance through the activation of G6PD-enhanced pentose phosphate pathway in hepatocellular carcinoma	24
circTGFBR2(3-6) acts as an assembly platform for RNA-binding protein IGF2BP3 and TGFBR1 mRNA to enhance breast cancer cell plasticity	24
Correction to: The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival	24
ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2	24
Current and novel approaches in yeast cell death research	24
AMBRA1 promotes intestinal inflammation by antagonizing PP4R1/PP4c mediated IKK dephosphorylation in an autophagy-independent manner	23
MARCH5 regulates mitotic apoptosis through MCL1-dependent and independent mechanisms	23
The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma	23
Methionine-driven YTHDF1 expression facilitates bladder cancer progression by attenuating RIG-I-modulated immune responses and enhancing the eIF5B-PD-L1 axis	23
DNMT1-mediated lncRNA IFFD controls the follicular development via targeting GLI1 by sponging miR-370	23
Designed Ankyrin Repeat Proteins as a tool box for analyzing p63	22
Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy	22
Localized release of muscle-generated BDNF regulates the initial formation of postsynaptic apparatus at neuromuscular synapses	22
An update on the tumor-suppressive functions of the RasGAP protein DAB2IP with focus on therapeutic implications	22
Crosstalk between O-GlcNAcylation and phosphorylation in metabolism: regulation and mechanism	22
Proteinase 3 depletion attenuates leukemia by promoting myeloid differentiation	22
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death	22
127aa encoded by circSpdyA promotes FA synthesis and NK cell repression in breast cancers	22
cGAS suppresses hepatocellular carcinoma independent of its cGAMP synthase activity	21
The JNK-EGR1 signaling axis promotes TNF-α-induced endothelial differentiation of human mesenchymal stem cells via VEGFR2 expression	21
S-Nitrosylation of cathepsin B affects autophagic flux and accumulation of protein aggregates in neurodegenerative disorders	21
Thymic egress and peripheral T cell homeostasis regulated by Rho GTPase-activating protein 30	21
Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly	21
Sphingosine kinase 2 deficiency impairs VLDL secretion by inhibiting mTORC2 phosphorylation and activating chaperone-mediated autophagy	21
LncRNA GLTC targets LDHA for succinylation and enzymatic activity to promote progression and radioiodine resistance in papillary thyroid cancer	21
KBTBD2 controls bone development by regulating IGF-1 signaling during osteoblast differentiation	20
RING1 dictates GSDMD-mediated inflammatory response and host susceptibility to pathogen infection	20
Ionizing radiation-induced mitophagy promotes ferroptosis by increasing intracellular free fatty acids	20
The USP1-WDR48 deubiquitinase complex functions as a molecular switch regulating tumor-associated macrophage activation and anti-tumor response	20
Multimodal detection of molecular residual disease in high-risk locally advanced squamous cell carcinoma of the head and neck	20
TP53: the unluckiest of genes?	20
USP2 promotes metabolic dysfunction-associated steatotic liver disease progression via stabilization of PPARγ	20
DUBA sustains the stability of NOD2 and RIPK2 to enhance innate immune responses	20
m6A demethylation of FOSL1 mRNA protects hepatoma cells against necrosis under glucose deprivation	20
c-Kit+ cells that intercalate with crypt Lgr5+ cells are distinctively multipotent in colonic epithelium renewal and repair	19
Inhibition of nucleo-cytoplasmic proteasome translocation by the aromatic amino acids or silencing Sestrin3—their sensing mediator—is tumor suppressive	19
The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis	19
PUMA-induced apoptosis drives bone marrow failure and genomic instability in telomerase-deficient mice	19
Integrated stress response plasticity governs normal cell adaptation to chronic stress via the PP2A-TFE3-ATF4 pathway	19
HSC70 mediated autophagic degradation of oxidized PRL2 is responsible for osteoclastogenesis and inflammatory bone destruction	19
CD95/Fas stoichiometry in future precision medicine	19
DUSP4 modulates RIG-I- and STING-mediated IRF3-type I IFN response	19
Caspase-8 expression and its Src dependent phosphorylation on Tyrosine 380 triggers NRF2 signaling activation in glioblastoma	19
Correction to: Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells	19
The histone demethylase Kdm6b regulates the maturation and cytotoxicity of TCRαβ+CD8αα+ intestinal intraepithelial lymphocytes	18
Targeting the BCKDK/BCLAF1/MYC/HK2 axis to alter aerobic glycolysis and overcome Trametinib resistance in lung cancer	18
Correction: SENP3 inhibition suppresses hepatocellular carcinoma progression and improves the efficacy of anti-PD-1 immunotherapy	18
CaSSiDI: novel single-cell “Cluster Similarity Scoring and Distinction Index” reveals critical functions for PirB and context-dependent Cebpb repression	18
Fatty acid synthesis promotes mtDNA release via ETS1-mediated oligomerization of VDAC1 facilitating endothelial dysfunction in sepsis-induced lung injury	18
STING directly interacts with PAR to promote apoptosis upon acute ionizing radiation-mediated DNA damage	18
GAS5 protects against nonalcoholic fatty liver disease via miR-28a-5p/MARCH7/NLRP3 axis-mediated pyroptosis	18
Genome-wide CRISPR screening identifies a role for ARRDC3 in TRP53-mediated responses	18
The p53 endoplasmic reticulum stress-response pathway evolved in humans but not in mice via PERK-regulated p53 mRNA structures	18
A novel auxin-inducible degron system for rapid, cell cycle-specific targeted proteolysis	18
CRISPR/Cas9-mediated inactivation of miR-34a and miR-34b/c in HCT116 colorectal cancer cells: comprehensive characterization after exposure to 5-FU reveals EMT and autophagy as key processes regulated	18
The integrated stress response in ischemic diseases	18
IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death	18
The embryonic patterning gene Dbx1 governs the survival of the auditory midbrain via Tcf7l2-Ap2δ transcriptional cascade	18
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions	18
Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc	18
High expression of PPP1CC promotes NHEJ-mediated DNA repair leading to radioresistance and poor prognosis in nasopharyngeal carcinoma	18
USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy	17
Regulating GSDMB pore formation: to ignite or inhibit?	17
Distinct developmental outcomes in DNA repair-deficient FANCC c.67delG mutant and FANCC−/− Mice	17
ZNF593 regulates the cGAS-mediated innate immune response by attenuating cGAS-DNA binding	17
Correction to: LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury	17
DCC/netrin-1 regulates cell death in oligodendrocytes after brain injury	17
The metabolic enzyme GYS1 condenses with NONO/p54nrb in the nucleus and spatiotemporally regulates glycogenesis and myogenic differentiation	16
A self-amplifying USP14-TAZ loop drives the progression and liver metastasis of pancreatic ductal adenocarcinoma	16
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy	16
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation	16
SCML2 contributes to tumor cell resistance to DNA damage through regulating p53 and CHK1 stability	16
DNA-PKcs regulates myogenesis in an Akt-dependent manner independent of induced DNA damage	16
Coordination between cell proliferation and apoptosis after DNA damage in Drosophila	16
Hornerin mediates phosphorylation of the polo-box domain in Plk1 by Chk1 to induce death in mitosis	16
LncRNA LY6E-DT and its encoded metastatic-related protein play oncogenic roles via different pathways and promote breast cancer progression	16
Role of Fra-2 in cancer	16