Cell Death and Differentiation

Article	Citations
COVID-19 vaccines: where we stand and challenges ahead	597
Cell cycle regulation: p53-p21-RB signaling	299
Cellular degradation systems in ferroptosis	278
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease	270
Molecular mechanisms of cell death in neurological diseases	266
The multifaceted role of ferroptosis in liver disease	218
An aberrant STAT pathway is central to COVID-19	212
Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities	196
p53 in ferroptosis regulation: the new weapon for the old guardian	192
Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)	182
Patients with COVID-19: in the dark-NETs of neutrophils	177
Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis	164
Ubiquitin signaling in cell cycle control and tumorigenesis	142
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation	142
Ubiquitination in the regulation of inflammatory cell death and cancer	140
Organelle-specific regulation of ferroptosis	139
Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics	129
Specific expression and functions of circular RNAs	115
Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells	113
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination	111
Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer	101
Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2	99
Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis	99
Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease	99
SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1	97

Ki-67 gene expression	91
CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression	91
PRMT4 promotes ferroptosis to aggravate doxorubicin-induced cardiomyopathy via inhibition of the Nrf2/GPX4 pathway	89
T cell apoptosis characterizes severe Covid-19 disease	86
Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis	85
YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect	84
Long noncoding RNA NEAT1 promotes ferroptosis by modulating the miR-362-3p/MIOX axis as a ceRNA	83
TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα	83
lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus	81
LINC00941 promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF-β/SMAD2/3 signaling pathway	80
Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis	79
Crosstalk between cGAS–STING signaling and cell death	78
The ubiquitin system: from cell signalling to disease biology and new therapeutic opportunities	77
Deubiquitinating enzyme OTUB1 promotes cancer cell immunosuppression via preventing ER-associated degradation of immune checkpoint protein PD-L1	76
GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy	75
The role of Ubiquitination in Apoptosis and Necroptosis	72
Adipogenesis of skeletal muscle fibro/adipogenic progenitors is affected by the WNT5a/GSK3/β-catenin axis	71
Targeting mitochondrial metabolism for precision medicine in cancer	70
Apoptotic cell death in disease—Current understanding of the NCCD 2023	70
SOCS2-enhanced ubiquitination of SLC7A11 promotes ferroptosis and radiosensitization in hepatocellular carcinoma	70
The regulation of necroptosis by post-translational modifications	70
Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment	69
ER-mitochondria contact sites in neurodegeneration: genetic screening approaches to investigate novel disease mechanisms	69
Immune response in COVID-19: what is next?	68
BH3 mimetics selectively eliminate chemotherapy-induced senescent cells and improve response in TP53 wild-type breast cancer	67
Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma	66
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis	65
Roles and mechanisms of BAP1 deubiquitinase in tumor suppression	64
Mutant p53: it’s not all one and the same	64
Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis	63
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration	62
The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses	62
MLKL in cancer: more than a necroptosis regulator	60
USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 1	60
KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway	60
Organoid-based modeling of intestinal development, regeneration, and repair	59
Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer’s mice	58
Organoid systems to study the human female reproductive tract and pregnancy	57
Functions of outer mitochondrial membrane proteins: mediating the crosstalk between mitochondrial dynamics and mitophagy	57
Gastric organoids—an in vitro model system for the study of gastric development and road to personalized medicine	57
Syncytia formation during SARS-CoV-2 lung infection: a disastrous unity to eliminate lymphocytes	56
Mitophagy protein PINK1 suppresses colon tumor growth by metabolic reprogramming via p53 activation and reducing acetyl-CoA production	55
The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute	55
Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease	53
IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages	53
Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment	53
Cuproptosis: p53-regulated metabolic cell death?	52
The miR-92a-2-5p in exosomes from macrophages increases liver cancer cells invasion via altering the AR/PHLPP/p-AKT/β-catenin signaling	51
PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma	51
Mitochondria and cell death-associated inflammation	51

E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer	49
Non-coding RNAs and ferroptosis: potential implications for cancer therapy	49
The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis	48
RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages	48
Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with disease	48
Of the many cellular responses activated by TP53, which ones are critical for tumour suppression?	47
Inhibition of Drp1 SUMOylation by ALR protects the liver from ischemia-reperfusion injury	47
Should mutant TP53 be targeted for cancer therapy?	47
Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation	46
Primidone blocks RIPK1-driven cell death and inflammation	45
M6A RNA methylation-mediated RMRP stability renders proliferation and progression of non-small cell lung cancer through regulating TGFBR1/SMAD2/SMAD3 pathway	45
p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways	45
HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1α-dependent acyloxyacyl hydrolase expression	44
EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma	44
ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation	44
Ubiquitin ligase E3 HUWE1/MULE targets transferrin receptor for degradation and suppresses ferroptosis in acute liver injury	44
The role of E3 ubiquitin ligases in the development and progression of glioblastoma	44
Functional crosstalk between myeloid Foxo1–β-catenin axis and Hedgehog/Gli1 signaling in oxidative stress response	43
Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer	42
Neuronal cell life, death, and axonal degeneration as regulated by the BCL-2 family proteins	42
Ubiquitination of NF-κB p65 by FBXW2 suppresses breast cancer stemness, tumorigenesis, and paclitaxel resistance	42
DAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagy	42
Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death	42
LncRNA NEAT1 controls the lineage fates of BMSCs during skeletal aging by impairing mitochondrial function and pluripotency maintenance	42
Circular RNA Cwc27 contributes to Alzheimer’s disease pathogenesis by repressing Pur-α activity	41
Cell death and inflammation during obesity: “Know my methods, WAT(son)”	41
The Met1-linked ubiquitin machinery in inflammation and infection	40
Building inner ears: recent advances and future challenges for in vitro organoid systems	40
Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma	40
Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy	39
Snail/PRMT5/NuRD complex contributes to DNA hypermethylation in cervical cancer by TET1 inhibition	39
UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance	39
Ubiquitin signaling in neurodegenerative diseases: an autophagy and proteasome perspective	39
Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice	39
Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL	39
CD9 induces cellular senescence and aggravates atherosclerotic plaque formation	38
Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis	38
Comorbidity-associated glutamine deficiency is a predisposition to severe COVID-19	38
p53-dependent elimination of aneuploid mitotic offspring by entosis	37
Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis	37
SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK	36
SARS-CoV-2 N501Y variants of concern and their potential transmission by mouse	36
Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation	36
MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly	35
A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells	35
MS4A15 drives ferroptosis resistance through calcium-restricted lipid remodeling	35
Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection	34
Targeting androgen receptor (AR) with antiandrogen Enzalutamide increases prostate cancer cell invasion yet decreases bladder cancer cell invasion via differentially altering the AR/circRNA-ARC1/miR-1	33
Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus	33
Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions	33
Selective ferroptosis vulnerability due to familial Alzheimer’s disease presenilin mutations	33
YAP–TEAD1 control of cytoskeleton dynamics and intracellular tension guides human pluripotent stem cell mesoderm specification	33
The circRNA CNEACR regulates necroptosis of cardiomyocytes through Foxa2 suppression	33
TLR4 downregulation by the RNA-binding protein PUM1 alleviates cellular aging and osteoarthritis	32
Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration	32
The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target	32
TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization	32
USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription	32
Build-UPS and break-downs: metabolism impacts on proteostasis and aging	32
Bedaquiline, an FDA-approved drug, inhibits mitochondrial ATP production and metastasis in vivo, by targeting the gamma subunit (ATP5F1C) of the ATP synthase	30
Met1-linked ubiquitin signalling in health and disease: inflammation, immunity, cancer, and beyond	30
Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt–β-catenin–STAT3 signaling	30
Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2	30
A novel HIF-2α targeted inhibitor suppresses hypoxia-induced breast cancer stemness via SOD2-mtROS-PDI/GPR78-UPRER axis	30
Epithelium- and endothelium-derived exosomes regulate the alveolar macrophages by targeting RGS1 mediated calcium signaling-dependent immune response	30
Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy	30
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin	30
O-GlcNAcylation of MORC2 at threonine 556 by OGT couples TGF-β signaling to breast cancer progression	30
TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1	29
Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer	29
Targeting triple-negative breast cancers with the Smac-mimetic birinapant	29
Opposing functions of β-arrestin 1 and 2 in Parkinson’s disease via microglia inflammation and Nprl3	29
LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2	29
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer	29
Trends and challenges in modeling glioma using 3D human brain organoids	29
Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries	29
BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer	29
Repression of p53 function by SIRT5-mediated desuccinylation at Lysine 120 in response to DNA damage	29
Necroptosis is dispensable for the development of inflammation-associated or sporadic colon cancer in mice	28
Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy	28

The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer	27
RIP3-mediated necroptosis is regulated by inter-filament assembly of RIP homotypic interaction motif	27
Sequential ubiquitination of p53 by TRIM28, RLIM, and MDM2 in lung tumorigenesis	27
Deubiquitylases in developmental ubiquitin signaling and congenital diseases	27
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function	27
Inhibiting the Pkm2/b-catenin axis drives in vivo replication of adult cardiomyocytes following experimental MI	27
Loss of Ryanodine Receptor 2 impairs neuronal activity-dependent remodeling of dendritic spines and triggers compensatory neuronal hyperexcitability	26
Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a	26
SPY1 inhibits neuronal ferroptosis in amyotrophic lateral sclerosis by reducing lipid peroxidation through regulation of GCH1 and TFR1	26
Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis	26
OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation	26
RUNX2 recruits the NuRD(MTA1)/CRL4B complex to promote breast cancer progression and bone metastasis	26
CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway	26
Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene	26
Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing	25
Beyond DNA repair and chromosome instability—Fanconi anaemia as a cellular senescence-associated syndrome	25
USP22 positively modulates ERα action via its deubiquitinase activity in breast cancer	25
The noncoding RNAs SNORD50A and SNORD50B-mediated TRIM21-GMPS interaction promotes the growth of p53 wild-type breast cancers by degrading p53	25
Deubiquitination of MYC by OTUB1 contributes to HK2 mediated glycolysis and breast tumorigenesis	25
USP42 drives nuclear speckle mRNA splicing via directing dynamic phase separation to promote tumorigenesis	25
SPOP mutations promote p62/SQSTM1-dependent autophagy and Nrf2 activation in prostate cancer	25
Targeting the miR-34a/LRPPRC/MDR1 axis collapse the chemoresistance in P53 inactive colorectal cancer	25
Ubiquitin-dependent and -independent functions of OTULIN in cell fate control and beyond	25
TEAD1 protects against necroptosis in postmitotic cardiomyocytes through regulation of nuclear DNA-encoded mitochondrial genes	25
The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson’s disease	25
N6-Methyladenosine-modified circSAV1 triggers ferroptosis in COPD through recruiting YTHDF1 to facilitate the translation of IREB2	24
TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer	24
SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis	24
MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions	24
Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation	24
Single-cell RNA-seq reveals novel mitochondria-related musculoskeletal cell populations during adult axolotl limb regeneration process	24
PKA compartmentalization links cAMP signaling and autophagy	24
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer	24
E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis	24
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth	24
Non-coding small nucleolar RNA SNORD17 promotes the progression of hepatocellular carcinoma through a positive feedback loop upon p53 inactivation	23
Activating transcription factor-4 promotes neuronal death induced by Parkinson’s disease neurotoxins and α-synuclein aggregates	23
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex	23
Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response	23
Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy	23
Long Covid: where we stand and challenges ahead	23
Site-specific ubiquitination of MLKL targets it to endosomes and targets Listeria and Yersinia to the lysosomes	23
Adaptors as the regulators of HECT ubiquitin ligases	23
dsDNA-induced AIM2 pyroptosis halts aberrant inflammation during rhabdomyolysis-induced acute kidney injury	23
Arginine hypomethylation-mediated proteasomal degradation of histone H4—an early biomarker of cellular senescence	23
The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1	23
The integrated stress response in ischemic diseases	23
Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection	23
Hypoxia-induced GLT8D1 promotes glioma stem cell maintenance by inhibiting CD133 degradation through N-linked glycosylation	23
Staufen 1 amplifies proapoptotic activation of the unfolded protein response	23
The Smad4-MYO18A-PP1A complex regulates β-catenin phosphorylation and pemigatinib resistance by inhibiting PAK1 in cholangiocarcinoma	23
Structural diversity of p63 and p73 isoforms	22
O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interaction	22
RGS5–TGFβ–Smad2/3 axis switches pro- to anti-apoptotic signaling in tumor-residing pericytes, assisting tumor growth	22
Dying in self-defence: a comparative overview of immunogenic cell death signalling in animals and plants	22
Kdm6a suppresses the alternative activation of macrophages and impairs energy expenditure in obesity	22
LRIK interacts with the Ku70–Ku80 heterodimer enhancing the efficiency of NHEJ repair	22
YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer	22
FOXF2 deficiency accelerates the visceral metastasis of basal-like breast cancer by unrestrictedly increasing TGF-β and miR-182-5p	21
Chemical activation of SAT1 corrects diet-induced metabolic syndrome	21
Selective autophagy controls the stability of TBK1 via NEDD4 to balance host defense	21
Olig2 SUMOylation protects against genotoxic damage response by antagonizing p53 gene targeting	21
Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS	21
PARsylated transcription factor EB (TFEB) regulates the expression of a subset of Wnt target genes by forming a complex with β-catenin-TCF/LEF1	21
Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL	21
The deubiquitinase JOSD2 is a positive regulator of glucose metabolism	21
Lymphotoxin: from the physiology to the regeneration of the thymic function	20
Non-canonical phosphorylation of Bmf by p38 MAPK promotes its apoptotic activity in anoikis	20
A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3	20
Coordination between cell proliferation and apoptosis after DNA damage in Drosophila	20
Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling	20
BAX and BAK dynamics control mitochondrial DNA release during apoptosis	20
Heart failure—emerging roles for the mitochondrial pyruvate carrier	20
The osteoprotective role of USP26 in coordinating bone formation and resorption	20
SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy	20
HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice	20
Palmitoylation restricts SQSTM1/p62-mediated autophagic degradation of NOD2 to modulate inflammation	20
Activation of Drp1 promotes fatty acids-induced metabolic reprograming to potentiate Wnt signaling in colon cancer	20
Therapeutic potential of Nlrp1 inflammasome, Caspase-1, or Caspase-6 against Alzheimer disease cognitive impairment	19
Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation	19
miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1	19
Arginine methyltransferase PRMT5 methylates and stabilizes KLF5 via decreasing its phosphorylation and ubiquitination to promote basal-like breast cancer	19
Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51	19
Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α	19
The long noncoding RNA Synage regulates synapse stability and neuronal function in the cerebellum	19
Targeting a positive regulatory loop in the tumor-macrophage interaction impairs the progression of clear cell renal cell carcinoma	19
PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors	19
Sustained intracellular calcium rise mediates neuronal mitophagy in models of autosomal dominant optic atrophy	18
MBD2 acts as a repressor to maintain the homeostasis of the Th1 program in type 1 diabetes by regulating the STAT1-IFN-γ axis	18
A self-amplifying USP14-TAZ loop drives the progression and liver metastasis of pancreatic ductal adenocarcinoma	18
Phosphorylation by Aurora B kinase regulates caspase-2 activity and function	18
The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein	18
Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation	18
Aquaporin 1 promotes sensitivity of anthracycline chemotherapy in breast cancer by inhibiting β-catenin degradation to enhance TopoIIα activity	18
Sirtuin 4 activates autophagy and inhibits tumorigenesis by upregulating the p53 signaling pathway	18