OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
The neuroimmune interface in retinal regeneration	198
Cell identity changes in ocular surface Epithelia	184
In vivo application of base and prime editing to treat inherited retinal diseases	162
Widefield OCT angiography	158
ICON-PM: International Consensus on Nomenclature for Adult Pathologic Myopia	148
Vogt-Koyanagi-Harada disease under the lens: Insights from multimodal ocular imaging	130
Phenotyping and genotyping FEVR: Molecular genetics, clinical and imaging features, and therapeutics	123
International consensuses and controversies on causes, diagnosis and management of diabetic macular edema (DME)	121
Non-vasogenic cystoid maculopathies	118
Animal models for the evaluation of retinal stem cell therapies	118
Editorial Board	111
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	101
Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation	99
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	97
Unravelling CYP4V2: Clinical features, genetic insights, pathogenic mechanisms and therapeutic strategies in Bietti crystalline corneoretinal dystrophy	89
Corneal stromal repair and regeneration	88
Central serous chorioretinopathy: An evidence-based treatment guideline	87
Editorial Board	87
Quantification of retinal microvascular imaging features from fundus photos in ocular and systemic disease: a framework for standardization	83
A paradigm shift in retinal detachment repair: The concept of integrity	81
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	81
Squishy matters – Corneal mechanobiology in health and disease	80
Myocilin misfolding and glaucoma: A 20-year update	78
Homeostatic plasticity in the retina	77
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	76

Are Müller glial cells gatekeepers of neuroprotection and regeneration in age-related macular degeneration? Unraveling their roles in pathophysiology and therapeutic innovation	72
Risk factors, clinical features and treatment of Behçet's disease uveitis	72
Cell fate decisions, transcription factors and signaling during early retinal development	71
The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	70
Femtosecond lasers in ophthalmology: Mechanisms, clinical breakthroughs, and multidisciplinary frontiers	68
Eye care adherence in pediatric and elderly: Understanding and addressing the challenges	64
RNA-targeting strategies as a platform for ocular gene therapy	62
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	61
Genetic architecture of congenital cataracts: correlation of pathogenic variants with morphology and clinical outcomes	59
How gut microbiota may impact ocular surface homeostasis and related disorders	59
The retinal pigmentation pathway in human albinism: Not so black and white	59
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	56
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	53
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	52
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	50
Scleral remodeling in myopia: mechanisms and therapeutic approaches	50
Retinal Manifestations of Alzheimer’s Disease: Insights from Animal Models, Clinical Detection, and Future Translation	49
Rhodopsin, light-sensor of vision	49
Editorial Board	48
Cellular component transfer between photoreceptor cells of the retina	48
Optical coherence tomography angiography in diabetic retinopathy	48
Pentosan polysulfate maculopathy: clinical considerations, pathobiology, and causality	47
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	46
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	45
Outer retinal tubulation associated with photoreceptor degeneration	44
Drug Delivery Across the Blood-Retinal Barrier: Biological Gateways for Posterior Segment Therapy	43
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	42
Regulation of lens water content: Effects on the physiological optics of the lens	41
Beyond convolutions and supervised learning with transformers and representation learning for retinal image analysis	41
Editorial Board	40
Interventions to reduce incidence and progression of myopia in children and adults	40
Editorial Board	39
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	39
Quantitative analysis of conjunctival vascular alterations: Applications in ocular and systemic disease detection	39
The march to harmonized imaging standards for retinal imaging	38
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	38
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	38
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	36
Gap Junctions Form Bridges between Bench Studies and Clinical Ophthalmology	35
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	35
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	34
The ocular surface in type 2 diabetes: pathophysiology and impact of anti-diabetic drugs	33
The relationship between intraocular pressure and glaucoma: An evolving concept	31
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	31
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation	31
Artificial intelligence in ophthalmology: Progress, challenges, and ethical implications	31
Minimally invasive glaucoma surgery in the surgical landscape of primary angle closure glaucoma: Current innovations and future trends	31
Clinical histopathology and pathogenesis of macular telangiectasia type 2	31
Eye on the horizon: The metabolic landscape of the RPE in aging and disease	30
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies,	30

Familial normal tension glaucoma genetics	28
“Vitreoretinal Bioadhesives: Translational Challenges and Innovative Perspectives”	28
The multifunctional human ocular melanocortin system	27
Potential therapeutic targets for age-related macular degeneration: The nuclear option	27
Polygenic risk scores for glaucoma: Impact on diagnosis and disease course	26
Glymphatic transport and ocular diseases	26
Zebrafish and inherited photoreceptor disease: Models and insights	26
The dark and bright sides of retinal G protein-coupled receptor (RGR) in vision and disease	26
Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy	25
Healing the cornea: Exploring the therapeutic solutions offered by MSCs and MSC-derived EVs	24
Value proposition of retinal imaging in Alzheimer's disease screening: A review of eight evolving trends	24
Decoding pediatric inherited retinal dystrophies: Bridging genetic complexity and clinical heterogeneity	24
Corrigendum to “Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362]	23
Syndromic retinitis pigmentosa	23
Aging, oxidative stress, and cataracts: Therapeutic prospects and translational insights into peroxiredoxin 6	23
Characterizing Bruch's membrane: State-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health	22
Latest advances in white spot syndromes: New findings and interpretations	21
Editorial Board	21
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy	21
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	20
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	20
Imaging of the retinal hypoxia: A journey from oxygen microelectrode to the first hypoxia imaging in the living retina	20
Retinal vessel imaging in inflammatory disease: From endothelial dysfunction to clinical evidence and translation	19
Structural photoreceptor evaluation in age-related macular degeneration. A comprehensive review of methods and clinical significance	19
Ocular gene therapy mediated by AAV vectors: an overview of immunosuppressive treatments and immunomonitoring of patients involved in clinical trials	19
The versatile roles of retinal pigment epithelium in the pathophysiology of retinitis pigmentosa	19
Eye–brain axis: Ocular and visual pathophysiology as driver and therapeutic target across the mood disorder trajectory	19
Ocular manifestations of COVID-19	18
Pericytes in the optic nerve head	18
Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration	17
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	17
The AI revolution in glaucoma: Bridging challenges with opportunities	17
Editorial Board	16
The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up	16
Eyelid dermatitis: Work-up and future diagnostic innovative solutions	16
Shining light on CRISPR/Cas9 therapeutics for inherited retinal diseases	16
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function	15
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases	15
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation	15
Therapy with voretigene neparvovec. How to measure success?	14
Bisretinoid lipofuscin, fundus autofluorescence and retinal disease	14
Optical coherence tomography in the management of diabetic macular oedema	14
Eyes shut homolog (EYS): Connecting molecule to disease	14
Comparative insights into the role of sex hormones in glaucoma among women and men	14
The physiology of dark adaptation: Progress and future directions	14
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications	14
Zinc in eye health, retinal biology and disease	13
Unsolved retinal questions	13
Safety and effectiveness of vital dyes for intraocular surgery	13
In vitro and ex vivo models of microbial keratitis: Present and future	13
Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches	13
Macular fibrosis secondary to neovascular age-related macular degeneration: from clinic to biology	12
Editorial Board	12
The role of the gut microbiome in eye diseases	12
AI in the clinical management of GA: A novel therapeutic universe requires novel tools	12
Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy	12