OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Widefield OCT angiography	234
The neuroimmune interface in retinal regeneration	233
In vivo application of base and prime editing to treat inherited retinal diseases	233
Cell identity changes in ocular surface Epithelia	143
Animal models for the evaluation of retinal stem cell therapies	138
Immunological aspects of RPE cell transplantation	121
Non-vasogenic cystoid maculopathies	120
Editorial Board	98
Unravelling CYP4V2: Clinical features, genetic insights, pathogenic mechanisms and therapeutic strategies in Bietti crystalline corneoretinal dystrophy	97
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	96
Corneal stromal repair and regeneration	94
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	93
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	92
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	88
Central serous chorioretinopathy: An evidence-based treatment guideline	88
Editorial Board	87
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	87
Squishy matters – Corneal mechanobiology in health and disease	80
Photocoagulation for retinal vein occlusion	78
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	78
Homeostatic plasticity in the retina	72
A paradigm shift in retinal detachment repair: The concept of integrity	71
Myocilin misfolding and glaucoma: A 20-year update	70
The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	70
Risk factors, clinical features and treatment of Behçet's disease uveitis	70

Cell fate decisions, transcription factors and signaling during early retinal development	66
Editorial Board	66
Protection against corneal hyperosmolarity with soft-contact-lens wear	64
The retinal pigmentation pathway in human albinism: Not so black and white	63
Genetic architecture of congenital cataracts: correlation of pathogenic variants with morphology and clinical outcomes	63
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	63
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	61
Approaches for corneal endothelium regenerative medicine	61
How gut microbiota may impact ocular surface homeostasis and related disorders	61
RNA-targeting strategies as a platform for ocular gene therapy	61
Cellular component transfer between photoreceptor cells of the retina	60
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	59
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	57
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	57
Rhodopsin, light-sensor of vision	56
Optical coherence tomography angiography in diabetic retinopathy	56
Editorial Board	55
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	54
Retinal pigment epithelium 65 kDa protein (RPE65): An update	53
Regulation of lens water content: Effects on the physiological optics of the lens	53
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	53
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	53
The march to harmonized imaging standards for retinal imaging	52
The retinal pigment epithelium: Development, injury responses, and regenerative potential in mammalian and non-mammalian systems	52
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	50
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	50
Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)	47
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	43
VEGFR1 signaling in retinal angiogenesis and microinflammation	43
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	43
Bacterial keratitis: identifying the areas of clinical uncertainty	43
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	42
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	41
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	41
Artificial intelligence in ophthalmology: Progress, challenges, and ethical implications	40
Editorial Board	39
Eye on the horizon: The metabolic landscape of the RPE in aging and disease	39
Prospects for the application of Müller glia and their derivatives in retinal regenerative therapies	38
Tilted disc syndrome (TDS): New hypotheses for posterior segment complications and their implications in other retinal diseases	37
The relationship between intraocular pressure and glaucoma: An evolving concept	37
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation	36
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies,	35
Value proposition of retinal imaging in Alzheimer's disease screening: A review of eight evolving trends	34
Potential therapeutic targets for age-related macular degeneration: The nuclear option	34
Familial normal tension glaucoma genetics	33
Zebrafish and inherited photoreceptor disease: Models and insights	33
The multifunctional human ocular melanocortin system	31
Syndromic retinitis pigmentosa	31
Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy	31
The dark and bright sides of retinal G protein-coupled receptor (RGR) in vision and disease	30

Healing the cornea: Exploring the therapeutic solutions offered by MSCs and MSC-derived EVs	30
Müller cells and astrocytes in tractional macular disorders	29
Characterizing Bruch's membrane: State-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health	27
Corrigendum to “Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362]	27
Translation of single-cell transcriptomic analysis of uveal melanomas to clinical oncology	27
Editorial Board	26
Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease	26
A reinterpretation of critical flicker-frequency (CFF) data reveals key details about light adaptation and normal and abnormal visual processing	26
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	25
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	25
Editorial Board	24
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy	24
Ocular manifestations of COVID-19	24
The two-faced effects of nerves and neuropeptides in corneal diseases	24
Latest advances in white spot syndromes: New findings and interpretations	24
The AI revolution in glaucoma: Bridging challenges with opportunities	23
Pericytes in the optic nerve head	23
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	21
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases	21
Editorial Board	21
Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration	20
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function	20
The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up	20
Shining light on CRISPR/Cas9 therapeutics for inherited retinal diseases	20
Optical coherence tomography in the management of diabetic macular oedema	19
Age and intraocular pressure in murine experimental glaucoma	19
Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches	18
Artificial intelligence in OCT angiography	18
Therapy with voretigene neparvovec. How to measure success?	18
In vitro and ex vivo models of microbial keratitis: Present and future	18
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation	18
Corrigendum to “Splicing mutations in inherited retinal diseases” [Prog. Retin. Eye Res. 80 (2021) 100874]	18
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications	18
AI in the clinical management of GA: A novel therapeutic universe requires novel tools	17
The role of the gut microbiome in eye diseases	17
Comparative insights into the role of sex hormones in glaucoma among women and men	17
Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities	17
Diabetic macular ischaemia- a new therapeutic target?	16
Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy	16
Editorial Board	15
Toward an internationally accepted standard for reading charts	14
IOP and glaucoma damage: The essential role of optic nerve head and retinal mechanosensors	14
Congenital aniridia beyond black eyes: From phenotype and novel genetic mechanisms to innovative therapeutic approaches	14
Editorial Board	14
Crosslinking with UV-A and riboflavin in progressive keratoconus: From laboratory to clinical practice – Developments over 25 years	14