OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
The neuroimmune interface in retinal regeneration	246
In vivo application of base and prime editing to treat inherited retinal diseases	239
Widefield OCT angiography	238
Cell identity changes in ocular surface Epithelia	150
Immunological aspects of RPE cell transplantation	141
Non-vasogenic cystoid maculopathies	128
Phenotyping and genotyping FEVR: Molecular genetics, clinical and imaging features, and therapeutics	124
Animal models for the evaluation of retinal stem cell therapies	102
Editorial Board	101
Unravelling CYP4V2: Clinical features, genetic insights, pathogenic mechanisms and therapeutic strategies in Bietti crystalline corneoretinal dystrophy	100
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	99
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	97
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	94
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	94
Central serous chorioretinopathy: An evidence-based treatment guideline	92
Corneal stromal repair and regeneration	89
Editorial Board	88
Squishy matters – Corneal mechanobiology in health and disease	82
Myocilin misfolding and glaucoma: A 20-year update	80
Risk factors, clinical features and treatment of Behçet's disease uveitis	80
A paradigm shift in retinal detachment repair: The concept of integrity	76
Photocoagulation for retinal vein occlusion	74
Homeostatic plasticity in the retina	73
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	72
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	72

Cell fate decisions, transcription factors and signaling during early retinal development	69
Editorial Board	68
The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	68
Protection against corneal hyperosmolarity with soft-contact-lens wear	66
RNA-targeting strategies as a platform for ocular gene therapy	64
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	63
Approaches for corneal endothelium regenerative medicine	62
How gut microbiota may impact ocular surface homeostasis and related disorders	62
Genetic architecture of congenital cataracts: correlation of pathogenic variants with morphology and clinical outcomes	62
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	61
The retinal pigmentation pathway in human albinism: Not so black and white	61
Cellular component transfer between photoreceptor cells of the retina	60
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	60
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	59
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	58
Editorial Board	57
Optical coherence tomography angiography in diabetic retinopathy	57
Rhodopsin, light-sensor of vision	57
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	55
Retinal pigment epithelium 65 kDa protein (RPE65): An update	55
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	55
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	54
Regulation of lens water content: Effects on the physiological optics of the lens	54
The retinal pigment epithelium: Development, injury responses, and regenerative potential in mammalian and non-mammalian systems	53
The march to harmonized imaging standards for retinal imaging	52
Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)	50
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	48
Bacterial keratitis: identifying the areas of clinical uncertainty	46
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	45
VEGFR1 signaling in retinal angiogenesis and microinflammation	45
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	45
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	45
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	44
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	43
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	42
Artificial intelligence in ophthalmology: Progress, challenges, and ethical implications	40
Editorial Board	40
Prospects for the application of Müller glia and their derivatives in retinal regenerative therapies	39
Tilted disc syndrome (TDS): New hypotheses for posterior segment complications and their implications in other retinal diseases	39
Eye on the horizon: The metabolic landscape of the RPE in aging and disease	39
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation	38
The relationship between intraocular pressure and glaucoma: An evolving concept	37
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies,	37
Potential therapeutic targets for age-related macular degeneration: The nuclear option	36
Zebrafish and inherited photoreceptor disease: Models and insights	36
Müller cells and astrocytes in tractional macular disorders	35
The multifunctional human ocular melanocortin system	33
Syndromic retinitis pigmentosa	33
Familial normal tension glaucoma genetics	33
Value proposition of retinal imaging in Alzheimer's disease screening: A review of eight evolving trends	31

Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy	31
The dark and bright sides of retinal G protein-coupled receptor (RGR) in vision and disease	31
Healing the cornea: Exploring the therapeutic solutions offered by MSCs and MSC-derived EVs	30
Characterizing Bruch's membrane: State-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health	30
Translation of single-cell transcriptomic analysis of uveal melanomas to clinical oncology	28
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	26
Corrigendum to “Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362]	26
Latest advances in white spot syndromes: New findings and interpretations	26
Editorial Board	26
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy	25
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	25
Editorial Board	24
The two-faced effects of nerves and neuropeptides in corneal diseases	24
Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease	24
The versatile roles of retinal pigment epithelium in the pathophysiology of retinitis pigmentosa	24
A reinterpretation of critical flicker-frequency (CFF) data reveals key details about light adaptation and normal and abnormal visual processing	24
Ocular manifestations of COVID-19	23
Pericytes in the optic nerve head	23
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	23
Editorial Board	22
The AI revolution in glaucoma: Bridging challenges with opportunities	22
The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up	21
Shining light on CRISPR/Cas9 therapeutics for inherited retinal diseases	21
Age and intraocular pressure in murine experimental glaucoma	21
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation	21
Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration	20
Optical coherence tomography in the management of diabetic macular oedema	20
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function	20
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases	20
Bisretinoid lipofuscin, fundus autofluorescence and retinal disease	20
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications	19
In vitro and ex vivo models of microbial keratitis: Present and future	19
Therapy with voretigene neparvovec. How to measure success?	19
Eyes shut homolog (EYS): Connecting molecule to disease	18
Comparative insights into the role of sex hormones in glaucoma among women and men	18
Artificial intelligence in OCT angiography	17
Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches	17
Corrigendum to “Splicing mutations in inherited retinal diseases” [Prog. Retin. Eye Res. 80 (2021) 100874]	17
Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy	17
Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities	16
AI in the clinical management of GA: A novel therapeutic universe requires novel tools	16
Diabetic macular ischaemia- a new therapeutic target?	16
The role of the gut microbiome in eye diseases	15
Editorial Board	14
Toward an internationally accepted standard for reading charts	14
AI explainability in oculomics: How it works, its role in establishing trust, and what still needs to be addressed	14
Editorial Board	14
Congenital aniridia beyond black eyes: From phenotype and novel genetic mechanisms to innovative therapeutic approaches	14