OOIR: Observatory of International Research

Papers

(The median citation count of Progress in Retinal and Eye Research is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
In vivo application of base and prime editing to treat inherited retinal diseases	290
The neuroimmune interface in retinal regeneration	224
Cell identity changes in ocular surface Epithelia	222
Immunological aspects of RPE cell transplantation	217
Non-vasogenic cystoid maculopathies	202
Animal models for the evaluation of retinal stem cell therapies	152
Promises and pitfalls of evaluating photoreceptor-based retinal disease with adaptive optics scanning light ophthalmoscopy (AOSLO)	134
Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions	130
Editorial Board	128
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens	123
Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives	115
Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration	106
The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas	104
Corneal stromal repair and regeneration	92
Central serous chorioretinopathy: An evidence-based treatment guideline	90
Editorial Board	89
Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)	88
Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors	86
Myocilin misfolding and glaucoma: A 20-year update	84
Risk factors, clinical features and treatment of Behçet's disease uveitis	84
A paradigm shift in retinal detachment repair: The concept of integrity	83
Squishy matters – Corneal mechanobiology in health and disease	82
Homeostatic plasticity in the retina	81
Photocoagulation for retinal vein occlusion	79
Cell fate decisions, transcription factors and signaling during early retinal development	75

The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease	75
Uncoupling proteins in the mitochondrial defense against oxidative stress	74
Editorial Board	72
Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration	72
Patient derived stem cells for discovery and validation of novel pathogenic variants in inherited retinal disease	65
Protection against corneal hyperosmolarity with soft-contact-lens wear	65
The retinal pigmentation pathway in human albinism: Not so black and white	65
Genetic Architecture of Congenital Cataracts: Correlation of Pathogenic Variants with Morphology and Clinical Outcomes	64
How gut microbiota may impact ocular surface homeostasis and related disorders	64
The vital role for nitric oxide in intraocular pressure homeostasis	63
RNA-targeting strategies as a platform for ocular gene therapy	62
Approaches for corneal endothelium regenerative medicine	61
Corrigendum to “Optical coherence tomography in the management of diabetic macular oedema” [Prog. Retin. Eye Res. 98 (2024) 101220]	61
Photoreceptor cells and RPE contribute to the development of diabetic retinopathy	61
Cellular component transfer between photoreceptor cells of the retina	60
Exploring single-cell RNA sequencing as a decision-making tool in the clinical management of Fuchs’ endothelial corneal dystrophy	59
Targeting inflammasomes and pyroptosis in retinal diseases—molecular mechanisms and future perspectives	58
Clinical vision and molecular loss: Integrating visual psychophysics with molecular genetics reveals key details of normal and abnormal visual processing	58
Rhodopsin, light-sensor of vision	58
Identification of novel biomarkers for retinopathy of prematurity in preterm infants by use of innovative technologies and artificial intelligence	57
Optical coherence tomography angiography in diabetic retinopathy	57
Editorial Board	56
Female carriers of X-linked inherited retinal diseases – Genetics, diagnosis, and potential therapies	54
Genetic therapies and potential therapeutic applications of CRISPR activators in the eye	54
The retinal pigment epithelium: Development, injury responses, and regenerative potential in mammalian and non-mammalian systems	54
Retinal pigment epithelium 65 kDa protein (RPE65): An update	54
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation	53
Regulation of lens water content: Effects on the physiological optics of the lens	52
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration	51
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma	51
The March to Harmonized Imaging Standards for Retinal Imaging	51
Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives	50
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity	49
Assessment and management of retinopathy of prematurity in the era of anti-vascular endothelial growth factor (VEGF)	49
Bacterial keratitis: identifying the areas of clinical uncertainty	48
VEGFR1 signaling in retinal angiogenesis and microinflammation	48
Translocator protein (18 kDa) (Tspo) in the retina and implications for ocular diseases	47
The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies	46
The role of CFTR in the eye, and the effect of early highly effective modulator treatment for cystic fibrosis on eye health	46
Past, present and future role of retinal imaging in neurodegenerative disease	43
Editorial Board	40
Optic nerve head anatomy in myopia and glaucoma, including parapapillary zones alpha, beta, gamma and delta: Histology and clinical features	40
Tilted disc syndrome (TDS): New hypotheses for posterior segment complications and their implications in other retinal diseases	40
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation	38
Aqueous outflow regulation – 21st century concepts	38
Eye on the horizon: The metabolic landscape of the RPE in aging and disease	38
The relationship between intraocular pressure and glaucoma: An evolving concept	37
Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies,	37
Prospects for the application of Müller glia and their derivatives in retinal regenerative therapies	37
Familial normal tension glaucoma genetics	35

Healing the cornea: Exploring the therapeutic solutions offered by MSCs and MSC-derived EVs	35
Value proposition of retinal imaging in Alzheimer's disease screening: A review of eight evolving trends	34
Zebrafish and inherited photoreceptor disease: Models and insights	33
The dark and bright sides of retinal G protein-coupled receptor (RGR) in vision and disease	33
Müller cells and astrocytes in tractional macular disorders	31
Dominant optic atrophy: Culprit mitochondria in the optic nerve	30
Potential therapeutic targets for age-related macular degeneration: The nuclear option	30
The multifunctional human ocular melanocortin system	29
Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy	29
Translation of single-cell transcriptomic analysis of uveal melanomas to clinical oncology	28
Characterizing Bruch's membrane: State-of-the-art imaging, computational segmentation, and biologic models in retinal disease and health	27
Corrigendum to “Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease” [Progr. Retin. Eye Res. 106 (2025) 101362]	27
Editorial Board	26
Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease	26
Cellular and subcellular optogenetic approaches towards neuroprotection and vision restoration	25
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy	25
A reinterpretation of critical flicker-frequency (CFF) data reveals key details about light adaptation and normal and abnormal visual processing	25
Latest advances in white spot syndromes: New findings and interpretations	24
The two-faced effects of nerves and neuropeptides in corneal diseases	24
Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms	24
Editorial Board	23
Ocular manifestations of COVID-19	23
The AI revolution in glaucoma: Bridging challenges with opportunities	23
Editorial Board	21
Pericytes in the Optic Nerve Head	21
Editorial Board	21
Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice	21
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function	20
The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up	20
Optical coherence tomography in the management of diabetic macular oedema	20
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases	20
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation	19
Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration	19
Age and intraocular pressure in murine experimental glaucoma	19
Corrigendum to “Splicing mutations in inherited retinal diseases” [Prog. Retin. Eye Res. 80 (2021) 100874]	18
Comparative insights into the role of sex hormones in glaucoma among women and men	18
In vitro and ex vivo models of microbial keratitis: Present and future	18
Punctate inner choroidopathy: A review of the current diagnostic and therapeutic approaches	17
Immune responses to retinal gene therapy using adeno-associated viral vectors – Implications for treatment success and safety	17
Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications	17
Artificial intelligence in OCT angiography	15
Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy	15
Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities	15
Therapy with voretigene neparvovec. How to measure success?	15
AI in the clinical management of GA: A novel therapeutic universe requires novel tools	15
The role of the gut microbiome in eye diseases	15
Single-cell RNA sequencing in vision research: Insights into human retinal health and disease	15
Diabetic macular ischaemia- a new therapeutic target?	15