Human Reproduction Update

Papers
(The median citation count of Human Reproduction Update is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
False hope for patients with Klinefelter syndrome on cryopreservation of spermatogonia at younger ages343
The pathophysiological role of estrogens in the initial stages of pregnancy: molecular mechanisms and clinical implications for pregnancy outcome from the periconceptional period to end of the first t177
Maternal and perinatal outcomes in twin pregnancies following assisted reproduction: a systematic review and meta-analysis involving 802 462 pregnancies161
Functional hypothalamic amenorrhoea and polycystic ovarian morphology: a narrative review about an intriguing association116
Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women116
Ultrasonographic criteria in the diagnosis of polycystic ovary syndrome: a systematic review and diagnostic meta-analysis106
Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis91
Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction84
Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis. Critical assessment of a review and meta-analysis83
Correction to: Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis78
Obstetric and neonatal outcomes of pregnancies resulting from preimplantation genetic testing: a systematic review and meta-analysis73
The complicated ART of finding consensus on family-building health policy: a comment on the IFFS consensus document72
What is the optimal GnRH antagonist protocol for ovarian stimulation during ART treatment? A systematic review and network meta-analysis71
Total fertilization failure after ICSI: insights into pathophysiology, diagnosis, and management through artificial oocyte activation68
Driving factors in treatment decision-making of patients seeking medical assistance for infertility: a systematic review67
Autophagy: a multifaceted player in the fate of sperm67
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene–disease relationships65
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries64
RNA modifications in female reproductive physiology and disease: emerging roles and clinical implications63
Obstetric and perinatal outcomes of singleton pregnancies after blastocyst-stage embryo transfer compared with those after cleavage-stage embryo transfer: a systematic review and cumulative meta-analy60
Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing60
HLA Class Ib-receptor interactions during embryo implantation and early pregnancy59
Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review53
The neglected members of the family: non-BRCAmutations in the Fanconi anemia/BRCA pathway and reproduction50
Reply: Artificial cycle frozen embryo transfer and obstetric adverse outcomes: association or causation?50
Assessing the influence of preconception diet on female fertility: a systematic scoping review of observational studies50
Prenatal and postnatal exposures to endocrine disrupting chemicals and timing of pubertal onset in girls and boys: a systematic review and meta-analysis50
IVF and human evolution49
What is the expected live birth rate per thawed oocyte?48
The missing role of diagnosis of confined placental mosaicism in the management of fetal growth restriction46
Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia45
Cell dynamics in human villous trophoblast45
Correction to: Evaluating interventions and adjuncts to optimize pregnancy outcomes in subfertile women: an overview review44
The LH surge and ovulation re-visited: a systematic review and meta-analysis and implications for true natural cycle frozen thawed embryo transfer44
Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine44
Administration of growth hormone improves endometrial function in women undergoing in vitro fertilization: a systematic review and meta-analysis43
COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss42
Infertility treatment and offspring blood pressure—a systematic review and meta-analysis41
Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies39
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain38
Reply: The missing role of diagnosis of confined placental mosaicism in the management of fetal growth restriction38
Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis36
Reply. How much evidence is needed to stop calling endometrial scratching ‘controversial’?36
Reply: What is the expected live birth rate per thawed oocyte?36
Molecular insights into sperm head shaping and its role in human male fertility35
Advances in non-hormonal male contraception targeting sperm motility33
Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility33
Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis32
The effects of bariatric surgery on periconception maternal health: a systematic review and meta-analysis32
The epigenetic approach of varicocele: a focus on sperm DNA and m6A-RNA methylation31
DNA methylation profiles after ART during human lifespan: a systematic review and meta-analysis31
Does the holy grail of the evidence pyramid vindicate the controversial practice of endometrial scratching or is there room for healthy skepticism?31
Moving toward totipotency: the molecular and cellular features of totipotent and naive pluripotent stem cells30
Bioengineering trends in female reproduction: a systematic review30
Spermatogonia: a unique stem cell orchestrating species-specific transition from pluripotency to sperm production30
Harnessing omics data for drug discovery and development in ovarian aging30
Correction to: Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women29
DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies29
The impact of primary ciliary dyskinesia on female and male fertility: a narrative review29
Anti-Müllerian hormone as a marker of ovarian reserve and premature ovarian insufficiency in children and women with cancer: a systematic review29
Remembering Professor John Collins28
Indoor and outdoor air pollution and couple fecundability: a systematic review28
Roles of bone morphogenetic proteins in endometrial remodeling during the human menstrual cycle and pregnancy21
Clinical application of aromatase inhibitors to treat male infertility21
TGFβ signalling: a nexus between inflammation, placental health and preeclampsia throughout pregnancy20
Reply. The role of endometrial scratching in IVF/ICSI: a critical appraisal of individual participant data meta-analysis20
Prevalence of PCOS and related hyperandrogenic traits in premenopausal women with type 1 diabetes: a systematic review and meta-analysis19
From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns19
Declining global fertility rates and the implications for family planning and family building: an IFFS consensus document based on a narrative review of the literature19
Reply: Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis. Critical assessment of a review and meta-analysis18
Impact of Bisphenol A and its alternatives on oocyte health: a scoping review18
A systematic review to determine use of the Endometriosis Health Profiles to measure quality of life outcomes in women with endometriosis18
Contribution of epididymal epithelial cell functions to sperm epigenetic changes and the health of progeny18
Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities18
Comparative efficacy of exercise, diet and/or pharmacological interventions on BMI, ovulation, and hormonal profile in reproductive-aged women with overweight or obesity: a systematic review and netwo17
Navigating fertility dilemmas across the lifespan in girls with Turner syndrome—a scoping review17
Immunotherapies to optimize pregnancy outcomes in subfertile women16
Evaluating the diagnostic accuracy of androgen measurement in polycystic ovary syndrome: a systematic review and diagnostic meta-analysis to inform evidence-based guidelines16
Anti-Müllerian hormone for the diagnosis and prediction of menopause: a systematic review16
Planned oocyte cryopreservation: a systematic review and meta-regression analysis16
Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis16
Reply: Endometrial scratching: the light at the end of the tunnel16
Transcriptional control of human gametogenesis16
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