Human Reproduction Update

Papers
(The median citation count of Human Reproduction Update is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
BMI in children aged 1–18 years conceived after ART with fresh and frozen embryo transfer: a systematic review and meta-analyses438
Maternal and perinatal outcomes in twin pregnancies following assisted reproduction: a systematic review and meta-analysis involving 802 462 pregnancies134
Building a human pluripotent stem cell-based gonadal niche: improving in vitro systems with in vivo insights123
Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women112
The pathophysiological role of estrogens in the initial stages of pregnancy: molecular mechanisms and clinical implications for pregnancy outcome from the periconceptional period to end of the first t107
Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis105
Functional hypothalamic amenorrhoea and polycystic ovarian morphology: a narrative review about an intriguing association95
Ultrasonographic criteria in the diagnosis of polycystic ovary syndrome: a systematic review and diagnostic meta-analysis94
Correction to: Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis91
The complicated ART of finding consensus on family-building health policy: a comment on the IFFS consensus document91
What is the optimal GnRH antagonist protocol for ovarian stimulation during ART treatment? A systematic review and network meta-analysis84
Total fertilization failure after ICSI: insights into pathophysiology, diagnosis, and management through artificial oocyte activation82
Preconception lifestyle interventions for women—a systematic review and meta-analysis of intervention characteristics and behaviour change techniques81
Driving factors in treatment decision-making of patients seeking medical assistance for infertility: a systematic review81
Autophagy: a multifaceted player in the fate of sperm79
Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review73
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries73
Obstetric, neonatal, and child health outcomes following embryo biopsy for preimplantation genetic testing70
RNA modifications in female reproductive physiology and disease: emerging roles and clinical implications70
HLA Class Ib-receptor interactions during embryo implantation and early pregnancy67
Prenatal and postnatal exposures to endocrine disrupting chemicals and timing of pubertal onset in girls and boys: a systematic review and meta-analysis64
Obstetric and perinatal outcomes of singleton pregnancies after blastocyst-stage embryo transfer compared with those after cleavage-stage embryo transfer: a systematic review and cumulative meta-analy63
Reply: Artificial cycle frozen embryo transfer and obstetric adverse outcomes: association or causation?58
The neglected members of the family: non-BRCAmutations in the Fanconi anemia/BRCA pathway and reproduction56
IVF and human evolution55
Assessing the influence of preconception diet on female fertility: a systematic scoping review of observational studies55
Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia53
What is the expected live birth rate per thawed oocyte?50
The LH surge and ovulation re-visited: a systematic review and meta-analysis and implications for true natural cycle frozen thawed embryo transfer49
Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine44
Infertility treatment and offspring blood pressure—a systematic review and meta-analysis43
Correction to: Evaluating interventions and adjuncts to optimize pregnancy outcomes in subfertile women: an overview review43
COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss42
Administration of growth hormone improves endometrial function in women undergoing in vitro fertilization: a systematic review and meta-analysis42
Novel microarchitecture of human endometrial glands: implications in endometrial regeneration and pathologies41
Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis40
Reply. How much evidence is needed to stop calling endometrial scratching ‘controversial’?40
Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility39
Reply: What is the expected live birth rate per thawed oocyte?39
Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis39
Molecular insights into sperm head shaping and its role in human male fertility38
Advances in non-hormonal male contraception targeting sperm motility38
Harnessing omics data for drug discovery and development in ovarian aging37
Bioengineering trends in female reproduction: a systematic review37
Does the holy grail of the evidence pyramid vindicate the controversial practice of endometrial scratching or is there room for healthy skepticism?37
DNA methylation profiles after ART during human lifespan: a systematic review and meta-analysis37
The epigenetic approach of varicocele: a focus on sperm DNA and m6A-RNA methylation35
Spermatogonia: a unique stem cell orchestrating species-specific transition from pluripotency to sperm production35
Moving toward totipotency: the molecular and cellular features of totipotent and naive pluripotent stem cells34
DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies34
Awareness and attitudes toward fertility preservation among healthcare providers: a scoping review of quantitative evidence33
The impact of primary ciliary dyskinesia on female and male fertility: a narrative review32
Anti-Müllerian hormone as a marker of ovarian reserve and premature ovarian insufficiency in children and women with cancer: a systematic review32
Correction to: Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women32
Remembering Professor John Collins31
Embryo metabolism as a novel non-invasive preimplantation test: nutrients turn over and metabolomic analysis of human spent embryo culture media (SECM)29
Roles of bone morphogenetic proteins in endometrial remodeling during the human menstrual cycle and pregnancy29
Indoor and outdoor air pollution and couple fecundability: a systematic review28
Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities27
Reply. The role of endometrial scratching in IVF/ICSI: a critical appraisal of individual participant data meta-analysis27
Prevalence of PCOS and related hyperandrogenic traits in premenopausal women with type 1 diabetes: a systematic review and meta-analysis27
TGFβ signalling: a nexus between inflammation, placental health and preeclampsia throughout pregnancy26
Declining global fertility rates and the implications for family planning and family building: an IFFS consensus document based on a narrative review of the literature26
Impact of Bisphenol A and its alternatives on oocyte health: a scoping review26
A systematic review to determine use of the Endometriosis Health Profiles to measure quality of life outcomes in women with endometriosis25
Bias busters: using the right risk-of-bias tools24
Transcript profiling and gene regulation of the human pre-implantation embryo: parental effects and impact of ARTs24
Navigating fertility dilemmas across the lifespan in girls with Turner syndrome—a scoping review24
The diagnosis and management of extrauterine and uterine ectopic pregnancy22
Comparative efficacy of exercise, diet and/or pharmacological interventions on BMI, ovulation, and hormonal profile in reproductive-aged women with overweight or obesity: a systematic review and netwo22
Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis22
Reply: Endometrial scratching: the light at the end of the tunnel21
Anti-Müllerian hormone for the diagnosis and prediction of menopause: a systematic review21
Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life20
Immunotherapies to optimize pregnancy outcomes in subfertile women20
BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis19
Transcriptional control of human gametogenesis18
Evaluating the diagnostic accuracy of androgen measurement in polycystic ovary syndrome: a systematic review and diagnostic meta-analysis to inform evidence-based guidelines18
Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies18
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