OOIR: Observatory of International Research

Papers

(The TQCC of Human Reproduction Update is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis	176
Endometrial function in women with polycystic ovary syndrome: a comprehensive review	150
Investigation of human trophoblast invasion in vitro	150
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries	148
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary	147
Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence	134
Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis	130
Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice	122
Endometriosis and cancer: a systematic review and meta-analysis	115
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene–disease relationships	113
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain	82
Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure	78
Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses	72
Endometriosis recurrence following post-operative hormonal suppression: a systematic review and meta-analysis	71
Mitochondria: their role in spermatozoa and in male infertility	68
Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies	68
Adenomyosis pathogenesis: insights from next-generation sequencing	62
Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis	61
Immunological changes associated with adenomyosis: a systematic review	59
Number and function of uterine natural killer cells in recurrent miscarriage and implantation failure: a systematic review and meta-analysis	58
IVF and other ART in low- and middle-income countries: a systematic landscape analysis	57
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction	55
Confined placental mosaicism and the association with pregnancy outcome and fetal growth: a review of the literature	54
Uterine natural killer cells: from foe to friend in reproduction	51
The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders	51

Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction	51
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions	51
Haploid male germ cells—the Grand Central Station of protein transport	48
Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome	47
Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis	46
DNA methylation in human sperm: a systematic review	43
Secretory products of the corpus luteum and preeclampsia	41
Preconception genome medicine: current state and future perspectives to improve infertility diagnosis and reproductive and health outcomes based on individual genomic data	41
Anti-Müllerian hormone as a marker of ovarian reserve and premature ovarian insufficiency in children and women with cancer: a systematic review	40
Nanoparticles in pregnancy: the next frontier in reproductive therapeutics	40
Embryo implantation in the laboratory: an update on current techniques	40
Current approaches and developments in transcript profiling of the human placenta	40
Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis	40
All you need to know about sperm RNAs	39
Autophagy: a multifaceted player in the fate of sperm	39
Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation	38
Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract	38
Modelling human embryogenesis: embryo-like structures spark ethical and policy debate	34
The dawn of the future: 30 years from the first biopsy of a human embryo. The detailed history of an ongoing revolution	34
Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety	34
Does an association exist between menstrual cycle length within the normal range and ovarian reserve biomarkers during the reproductive years? A systematic review and meta-analysis	33
SARS-CoV-2, fertility and assisted reproduction	32
Obstetric and neonatal outcomes of pregnancies resulting from preimplantation genetic testing: a systematic review and meta-analysis	31
The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review	31
Studying human reproductive biology through single-cell analysis and in vitro differentiation of stem cells into germ cell-like cells	31
Cell dynamics in human villous trophoblast	31