OOIR: Observatory of International Research

Papers

(The median citation count of Cell Stress & Chaperones is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Heat shock protein A12A activates migration of hepatocellular carcinoma cells in a monocarboxylate transporter 4–dependent manner	151
Elevation of major constitutive heat shock proteins is heat shock factor independent and essential for establishment and growth of Lgl loss and Yorkie gain-mediated tumors in Drosophila	103
Loss of the histone chaperone UNC-85/ASF1 inhibits the epigenome-mediated longevity and modulates the activity of one-carbon metabolism	45
Responses of multifunctional immune complement component 1q (C1q) and apoptosis-related genes in Macrophthalmus japonicus tissues and human cells following exposure to environmental pollutants	41
Flow cytometry FRET reveals post-translational modifications drive Protein Phosphatase-5 conformational changes in mammalian cells	38
Corrigendum to “The mechanism and therapeutic strategies in doxorubicin induced cardiotoxicity: Role of programmed cell death” [Cell Stress Chaperones. 2024;29:666-680]	34
Retraction Note: Sirtuin 3 inhibition induces mitochondrial stress in tongue cancer by targeting mitochondrial fission and the JNK-Fis1 biological axis	31
Ceapin-A7 suppresses the protective effects of Octreotide in human and bovine lung endothelial cells	28
Investigation of inflammation, oxidative stress, and DNA damage in COVID-19 patients	26
Aucubin promotes activation of AMPK and alleviates cerebral ischemia/reperfusion injury in rats	25
Protective effects of epigallocatechin-3-gallate counteracting the chronic hypobaric hypoxia-induced myocardial injury in plain-grown rats at high altitude	23
Partial limitation of cellular functions and compensatory modulation of unfolded protein response pathways caused by double-knockout of ATF6α and ATF6β	23
Cover and caption	20
Discovery and validation of a novel inhibitor of HYPE-mediated AMPylation	18
Transgenerational transmission of environmental effects in livestock in the age of global warming	17
Heat shock protein 90 (Hsp90) inhibitor STA-9090 (Ganetespib) ameliorates inflammation in a mouse model of atopic dermatitis	17
ArHsp90 is important in stress tolerance and embryo development of the brine shrimp, Artemia franciscana	17
Second international symposium on the chaperone code, 2023	17
Human HSP70-escort protein 1 (hHep1) interacts with negatively charged lipid bilayers and cell membranes	17
Hsp90 and phosphorylation of the Slt2(Mpk1) MAP kinase activation loop are essential for catalytic, but not non-catalytic, Slt2-mediated transcription in yeast	15
Cover and caption	15
Construction of a prognostic model for lung adenocarcinoma based on heat shock protein-related genes and immune analysis	14
Molecular characterization of six heat shock protein 70 genes from Arma chinensis and their expression patterns in response to temperature stress	14
FKBP51 overexpression in the corticolimbic system stabilizes circadian rhythms	14
Oxidative stress responses as a marker of toxicity in mice exposed to polluted groundwater from an automobile junk market in South-Western Nigeria	13

An interactome analysis reveals that Arabidopsis thaliana GRDP2 interacts with proteins involved in post-transcriptional processes	13
Editorial Board Members/Copyright	13
RETRACTED ARTICLE: circABCA3 knockdown relieves hypoxia-induced human cardiac microvascular endothelial cell dysfunction by targeting the miR-671-5p/PCSK9 axis	12
Diversity in heat shock protein families: functional implications in virus infection with a comprehensive insight of their role in the HIV-1 life cycle	12
Ameliorative effects of Bifidobacterium longum peptide-1 on benzo(α)pyrene induced oxidative damages via daf-16 in Caenorhabditis elegans	12
Increased intracellular stress responses and decreased KLF2 in adult patients with atopic dermatitis	12
Caspase-mediated cleavage of miRNA processing proteins Drosha, DGCR8, Dicer, and TRBP2 in heat-shocked cells and its inhibition by HSP70 overexpression	12
Hemin protects against cell stress induced by estrogen and progesterone in rat mammary glands via modulation of Nrf2/HO-1 and NF-κB pathways	12
Sequence similarity of HSP65 of Mycobacterium bovis BCG with SARS-CoV-2 spike and nuclear proteins: may it predict an antigen-dependent immune protection of BCG against COVID-19?	12
HSPA12A stimulates “Smurf1-Hif1α-aerobic glycolysis” axis to promote proliferation of renal tubular epithelial cells after hypoxia/reoxygenation injury	11
Transcriptional regulation of small heat shock protein genes by heat shock factor 1 (HSF1) in Liriomyza trifolii under heat stress	11
Prophylactic role of olive fruit extract against cigarette smoke–induced oxidative stress in Sprague–Dawley rats	11
Is the lipochaperone activity of sHSP a key to the stress response encoded in its primary sequence?	11
The abrogation of GRP78 sensitizes liver cancer cells to lysionotin by enhancing ER stress-mediated pro-apoptotic pathway	11
Correction to: Elevated circulating Hsp70 levels are correlative for malignancies in different mammalian species	11
Elevated seasonal temperature disrupts prooxidant-antioxidant homeostasis and promotes cellular apoptosis in the American oyster, Crassostrea virginica, in the Gulf of Mexico: a field study	11
Heat shock response during the resolution of inflammation and its progressive suppression in chronic-degenerative inflammatory diseases	11
Biochemical characterization of ClpB and DnaK from Anaplasma phagocytophilum	10
Endoplasmic reticulum-unfolded protein response pathway modulates the cellular response to mitochondrial proteotoxic stress	10
Mechanism of miR-34a in the metabolism of extracellular matrix in fibroblasts of stress urinary incontinence via Nampt-mediated autophagy	10
Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro	10
The Keap1 signaling in the regulation of HSP90 pathway	10
Comparison between two cryopreservation techniques of human ovarian cortex: morphological aspects and the heat shock response (HSR)	10
FKBP51 functions in the regulation of circadian rhythm and Alzheimer's disease	9
Melatonin ameliorates heat stress-induced oxidative apoptosis in mouse spermatocytes via autophagy and ferroptosis pathways	9
Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8–9, 2022	9
Expansion of the HSP70 gene family in Tegillarca granosa and expression profiles in response to zinc toxicity	9
Elevated circulating Hsp70 levels are correlative for malignancies in different mammalian species	9
HSP70 as a biomarker of the thin threshold between benefit and injury due to physical exercise when exposed to air pollution	9
Nutri-stress, mitochondrial dysfunction, and insulin resistance—role of heat shock proteins	9
Proteotoxic stress-induced autophagy is regulated by the NRF2 pathway via extracellular vesicles	8
Correction: Mechanism of miR-34a in the metabolism of extracellular matrix in fibroblasts of stress urinary incontinence via Nampt-mediated autophagy	8
Cover and caption	8
Hsp90: Bringing it all together	8
Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies	8
Extracellular metallothionein as a therapeutic target in the early progression of type 1 diabetes	8
Investigation of endoplasmic reticulum stress-regulated chaperones as biomarkers in idiopathic nonobstructive azoospermia	8
Genome-wide DNA methylation profiles regulate distinct heat stress response in zebu (Bos indicus) and crossbred (Bos indicus × Bos taurus) cattle	8
Editorial Board Members/Copyright	8
Mechanisms involved in the regulation of mitochondrial quality control by PGAM5 in heart failure	8
The environmental cellular stress response: the intertidal as a multistressor model	8
Transcription factor Nrf2 as a potential therapeutic target for COVID-19	8
Chronic stress promotes gastric cancer progression via the adrenoceptor beta 2/PlexinA1 pathway	8
Comprehensive analysis of human tissues reveals unique expression and localization patterns of HSF1 and HSF2	8
Oxidative stress and neuroimmune proteins in a mouse model of autism	8
Hsf1 and Hsf2 in normal, healthy human tissues: Immunohistochemistry provokes new questions	8
Will artificial intelligence require chaperones?	8
The role of endoplasmic reticulum stress in endometriosis	7
The combination of hypoxia and high temperature affects heat shock, anaerobic metabolism, and pentose phosphate pathway key components responses in the white shrimp (Litopenaeus vannamei)	7
Nicotinamide mononucleotide supplementation mitigates osteopenia induced by modeled microgravity in rats	7

Innate extracellular mouse Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors	7
Functional assessment of the V390F mutation in the CCTδ subunit of chaperonin containing tailless complex polypeptide 1	7
Research is life itself: in memory of Takashi Yura	7
Reduced male fertility of an Antarctic mite following extreme heat stress could prompt localized population declines	7
HSPA2 Emerges as a Key Biomarker: Insights from Global Lysine Acetylproteomic Profiling in Idiopathic Male Infertility	7
Autophagy and unfolded protein response induction: a crosstalk between street rabies virus and the host	6
Seasonal plasticity in immunocompetent cytokines (IL-2, IL-6, and TNF-α), myeloid progenitor cell (CFU-GM) proliferation, and LPS-induced oxido-inflammatory aberrations in a tropical rodent Funambulus	6
Secreted extracellular heat shock protein gp96 and inflammatory cytokines are markers of severe malaria outcome	6
In an experimental myocardial infarction model, L-arginine pre-intervention may exert cardioprotective effects by regulating OTULIN levels and mitochondrial dynamics	6
Pyrotinib induces cell death in HER2-positive breast cancer via triggering HSP90-dependent HER2 degradation and ROS/HSF-1-dependent oxidative DNA damage	6
JNK signaling dominance in hyperthermia	6
ER-stress-induced secretion of circulating glucose-regulated protein 78kDa (GRP78) ameliorates pulmonary artery smooth muscle cell remodelling	6
Circular RNA circ_0008896 contributes to oxidized low-density lipoprotein-induced aortic endothelial cell injury via targeting miR-188-3p/NOD2 axis	6
Novel insights into the involvement of mitochondrial fission/fusion in heart failure: From molecular mechanisms to targeted therapies	6
ACY-1215 suppresses the proliferation and induces apoptosis of chronic myeloid leukemia cells via the ROS/PTEN/Akt pathway	6
Autorepression of yeast Hsp70 cochaperones by intramolecular interactions involving their J-domains	6
Chemogenomic and bioinformatic profiling of ERdj paralogs underpins their unique roles in cancer	6
A novel synthetic chalcone derivative, 2,4,6-trimethoxy-4′-nitrochalcone (Ch-19), exerted anti-tumor effects through stimulating ROS accumulation and inducing apoptosis in esophageal cancer cells	6
Editorial Board Members/Copyright	6
Hsp90 chaperone code and the tumor suppressor VHL cooperatively regulate the mitotic checkpoint	6
Protective effect of hydrogen sulfide against stress-induced lung injury: involvement of Nrf2, NFκB/iNOS, and HIF-1α signaling pathways	6
Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS	5
Extracellular Metallothionein: An Alarmin Regulating Lymphocyte Gene Expression, Cell Signaling, and Immune Function	5
Molecular response of canine testis to GnRH agonist: Insights into AR, HIF-1α, and HSPs expression during arrest and recovery of spermatogenesis	5
Editorial Board Members/Copyright	5
Plasmodium falciparum heat shock proteins as antimalarial drug targets: An update	5
A subfamily of the small heat shock proteins of the marine red alga Neopyropia yezoensis localizes in the chloroplast	5
Temperature response of enriched pre-pubertal caprine male germline stem cells in vitro	5
Coping with harsh heat environments: molecular adaptation of metabolic depression in the intertidal snail Echinolittorina radiata	5
Tenth International Symposium on the Hsp90 chaperone machine	5
PROGRESS STUDY: Progression of chronic kidney disease in children and heat shock proteins	5
PBX1 attenuates H2O2-induced oxidant stress in human trabecular meshwork cells via promoting NANOG-mediated PI3K/AKT signaling pathway	5
The role of the FKBP51–Hsp90 complex in Alzheimer’s disease: An emerging new drug target	5
CHOP aggravates hepatocyte apoptosis upon endoplasmic reticulum stress by downregulating autophagy	5
HDAC1 is involved in the destabilization of the HSF2 protein under nonstress and stress conditions	5
Tanshinone IIA protects mouse testes from heat stress injury by inhibiting apoptosis and TGFβ1/Smad2/Smad3 signaling pathway	5
Editorial: A new chapter for Cell Stress and Chaperones	4
HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells	4
An update on the status of HSP90 inhibitors in cancer clinical trials	4
Cover and caption	4
Cover and caption	4
Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome i	4
Increased eHSP70-to-iHSP70 ratio in prediabetic and diabetic postmenopausal women: a biomarker of cardiometabolic risk	4
An association study of the HSPA8 gene polymorphisms with schizophrenia in a Polish population	4
The effect of tropisetron on peripheral diabetic neuropathy: possible protective actions against inflammation and apoptosis	4
Cellular protection from H2O2 toxicity by Fv-Hsp70: protection via catalase and gamma-glutamyl-cysteine synthase	4
Role of unfolded protein response and ER-associated degradation under freezing, anoxia, and dehydration stresses in the freeze-tolerant wood frogs	4
RETRACTED: Role of mitochondria in doxorubicin-mediated cardiotoxicity: From molecular mechanisms to therapeutic strategies	4
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia–reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis	4
Influence of body composition and cardiorespiratory fitness on plasma HSP72, norepinephrine, insulin, and glucose responses to an acute aerobic exercise bout performed in the fed state	4
SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway	4
Identification and expression analysis of heat shock protein family genes of gall fly (Procecidochares utilis) under temperature stress	4
Takashi Yura—in memory of an inspiring pioneer of the bacterial heat shock response	4
Gambogic acid and gambogenic acid induce a thiol-dependent heat shock response and disrupt the interaction between HSP90 and HSF1 or HSF2	4
Trends in HSPB5 research: a 36-year bibliometric analysis	3
Publisher Correction: Extracellular Hsp90α stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress	3
Cover and caption	3
The mechanism and therapeutic strategies in doxorubicin-induced cardiotoxicity: Role of programmed cell death	3
A review on oligomeric polydispersity and oligomers-dependent holding chaperone activity of the small heat-shock protein IbpB of Escherichia coli	3
Large-scale energy decomposition for the analysis of protein stability	3
Retraction Note: Carvedilol protection against endogenous Aβ-induced neurotoxicity in N2a cells	3
Circulating heat shock protein 90 (Hsp90) in atopic dermatitis and bullous pemphigoid: is there a link?	3
Roles of heat shock protein A12A in the development of diabetic cardiomyopathy	3
ROS inhibition increases KDM6A-mediated NOX2 transcription and promotes macrophages oxidative stress and M1 polarization	3
Cover and caption	3
Corrigendum to “Melatonin ameliorates heat stress-induced oxidative apoptosis in mouse spermatocytes via autophagy and ferroptosis pathways” [Cell Stress Chaperones. 2025;30:100078]	3
Antioxidant effects of bis-indole alkaloid indigo and related signaling pathways in the experimental model of Duchenne muscular dystrophy	3
RNA binding motif protein 3 (RBM3) promotes protein kinase B (AKT) activation to enhance glucose metabolism and reduce apoptosis in skeletal muscle of mice under acute cold exposure	3
Introduction of Dimitra Bourboulia as the new Editor-in-Chief of Cell Stress & Chaperones	3
Editorial Board Members/Copyright	3
Camel whey protein alleviates heat stress-induced liver injury by activating the Nrf2/HO-1 signaling pathway and inhibiting HMGB1 release	3
LED therapy plus idebenone treatment targeting calcium and mitochondrial signaling pathways in dystrophic muscle cells	3
Mutations F352A and Y528A in human HSP90α reduce fibronectin association and fibrillogenesis in cell-derived matrices.	3
Circulating heat shock protein 90 (Hsp90) and autoantibodies to Hsp90 are increased in patients with atopic dermatitis	3
Letter to Professor Currie	3
Endoplasmic reticulum stress-mediated cell death in cardiovascular disease	3
Reviewer acknowledgements	3