OOIR: Observatory of International Research

Papers

(The TQCC of Cell Stress & Chaperones is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
SARS-CoV-2 and Guillain-Barré syndrome: molecular mimicry with human heat shock proteins as potential pathogenic mechanism	99
Human molecular chaperones share with SARS-CoV-2 antigenic epitopes potentially capable of eliciting autoimmunity against endothelial cells: possible role of molecular mimicry in COVID-19	81
The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress?	78
Activation of NRF2/FPN1 pathway attenuates myocardial ischemia–reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis	60
Small heat shock proteins in neurodegenerative diseases	54
Nrf2/ARE is a key pathway for curcumin-mediated protection of TMJ chondrocytes from oxidative stress and inflammation	47
COVID-19 and heme oxygenase: novel insight into the disease and potential therapies	45
Is COVID-19 a proteiform disease inducing also molecular mimicry phenomena?	44
The multifaceted nature of αB-crystallin	35
Stress and immunity in poultry: light management and nanotechnology as effective immune enhancers to fight stress	34
Central role of 70-kDa heat shock protein in adaptation of plants to drought stress	34
Crosstalk between endoplasmic reticulum stress and oxidative stress in the progression of diabetic nephropathy	33
Small heat-shock proteins and their role in mechanical stress	32
Effect of di(2-ethylhexyl) phthalate on Nrf2-regulated glutathione homeostasis in mouse kidney	31
Structural aspects of the human small heat shock proteins related to their functional activities	29
Possible application of H2S-producing compounds in therapy of coronavirus (COVID-19) infection and pneumonia	29
Human Hsp90 cochaperones: perspectives on tissue-specific expression and identification of cochaperones with similar in vivo functions	29
Psychrophilic Pseudomonas helmanticensis proteome under simulated cold stress	28
Structure and function of the co-chaperone protein phosphatase 5 in cancer	28
COVID-19, acute respiratory distress syndrome (ARDS), and hyperbaric oxygen therapy (HBOT): what is the link?	26
Inhibition of hsa_circ_0002570 suppresses high-glucose–induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-1243/angiomotin axis	24
The interaction of heat shock proteins with cellular membranes: a historical perspective	24
The multiple organs insult and compensation mechanism in mice exposed to hypobaric hypoxia	23
Diversity in heat shock protein families: functional implications in virus infection with a comprehensive insight of their role in the HIV-1 life cycle	22
Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attention	22

The mitochondria-targeted antioxidant MitoQ ameliorates myocardial ischemia–reperfusion injury by enhancing PINK1/Parkin-mediated mitophagy in type 2 diabetic rats	21
O-GlcNAcylation: the “stress and nutrition receptor” in cell stress response	20
Urolithin A induces cell cycle arrest and apoptosis by inhibiting Bcl-2, increasing p53-p21 proteins and reactive oxygen species production in colorectal cancer cells	20
Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies	19
Peeking from behind the veil of enigma: emerging insights on small heat shock protein structure and function	19
Hydrolyzed camel whey protein alleviated heat stress-induced hepatocyte damage by activated Nrf2/HO-1 signaling pathway and inhibited NF-κB/NLRP3 axis	19
MiR-17-5p-mediated endoplasmic reticulum stress promotes acute myocardial ischemia injury through targeting Tsg101	19
Ebola virus glycoprotein GP1—host cell-surface HSPA5 binding site prediction	19
Gambogic acid ameliorates high glucose– and palmitic acid–induced inflammatory response in ARPE-19 cells via activating Nrf2 signaling pathway: ex vivo	18
Exogenous recombinant Hsp70 mediates neuroprotection after photothrombotic stroke	18
Lipid chaperones and associated diseases: a group of chaperonopathies defining a new nosological entity with implications for medical research and practice	18
Structural and functional properties of proteins interacting with small heat shock proteins	17
Comparative analysis of differential gene expression of HSP40 and HSP70 family isoforms during heat stress and HIV-1 infection in T-cells	17
Interaction of HSPA5 (Grp78, BIP) with negatively charged phospholipid membranes via oligomerization involving the N-terminal end domain	17
An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space	17
MicroRNA-214-3p aggravates ferroptosis by targeting GPX4 in cisplatin-induced acute kidney injury	16
Human heat shock cognate protein (HSC70/HSPA8) interacts with negatively charged phospholipids by a different mechanism than other HSP70s and brings HSP90 into membranes	15
Mutations in HspB1 and hereditary neuropathies	15
Heat stress promotes lipid accumulation by inhibiting the AMPK-PGC-1α signaling pathway in 3T3-L1 preadipocytes	15
Identification of five small heat shock protein genes in Spodoptera frugiperda and expression analysis in response to different environmental stressors	15
CIGB-258, a peptide derived from human heat-shock protein 60, decreases hyperinflammation in COVID-19 patients	15
Exported plasmodial J domain protein, PFE0055c, and PfHsp70-x form a specific co-chaperone-chaperone partnership	15
The effect of hyperbaric oxygen on mitochondrial and glycolytic energy metabolism: the caloristasis concept	15
β-Glucan from Saccharomyces cerevisiae alleviates oxidative stress in LPS-stimulated RAW264.7 cells via Dectin-1/Nrf2/HO-1 signaling pathway	15
Genome-wide analysis of Hsp70 and Hsp100 gene families in Ziziphus jujuba	14
Autologous extracellular Hsp70 exerts a dual role in rheumatoid arthritis	14
HTR2A promotes the development of cardiac hypertrophy by activating PI3K-PDK1-AKT-mTOR signaling	14
Berberine attenuates mitochondrial dysfunction by inducing autophagic flux in myocardial hypoxia/reoxygenation injury	14
Multivalent protein–protein interactions are pivotal regulators of eukaryotic Hsp70 complexes	13
Iron depletion with deferoxamine protects bone marrow-derived mesenchymal stem cells against oxidative stress-induced apoptosis	13
Hsp70 affects memory formation and behaviorally relevant gene expression in Drosophila melanogaster	13
Direct exposure to mild heat stress stimulates cell viability and heat shock protein expression in primary cultured broiler fibroblasts	13
Involvement of CDKN1A (p21) in cellular senescence in response to heat and irradiation stress during preimplantation development	13
Small but mighty: a functional look at bacterial sHSPs	12
Inhibition of USP14 induces ER stress–mediated autophagy without apoptosis in lung cancer cell line A549	12
Heat shock proteins and the biogenesis of cellular membranes	12
Dynamic changes in blood immune cell composition and function in Holstein and Jersey steers in response to heat stress	12
Elevated seasonal temperature disrupts prooxidant-antioxidant homeostasis and promotes cellular apoptosis in the American oyster, Crassostrea virginica, in the Gulf of Mexico: a field study	12
Short-term cold stress and heat shock proteins in the crustacean Artemia franciscana	12
Chronic heat treatment positively impacts metabolic profile of ovariectomized rats: association with heat shock response pathways	12
Towards an understanding of the role of intrinsic protein disorder on plant adaptation to environmental challenges	12
Tissue-specific effects of temperature on proteasome function	12
Heat shock protein 90 and NFkB levels in serum and urine in patients with chronic glomerulonephritis	12
Increased expression and retention of the secretory chaperone proSAAS following cell stress	11
Stress-induced changes in CARF expression determine cell fate to death, survival, or malignant transformation	11
AlphaB-crystallin and breast cancer: role and possible therapeutic strategies	11
Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate	11
The immunopathobiology of T cells in stress condition: a review	10
The role of PSMB5 in sodium arsenite–induced oxidative stress in L-02 cells	10
The effects of cold stress on Mytilus species in the natural environment	10

Heat-induced endoplasmic reticulum stress in soleus and gastrocnemius muscles and differential response to UPR pathway in rats	10
Elabela blunts doxorubicin-induced oxidative stress and ferroptosis in rat aortic adventitial fibroblasts by activating the KLF15/GPX4 signaling	10
Neutralizing the free radicals could alleviate the disease severity following an infection by positive strand RNA viruses	10
Endoplasmic reticulum-unfolded protein response pathway modulates the cellular response to mitochondrial proteotoxic stress	10
ER stress-related molecules induced by Hantaan virus infection in differentiated THP-1 cells	9
Gene network analyses support subfunctionalization hypothesis for duplicated hsp70 genes in the Antarctic clam	9
HSP70 as a biomarker of the thin threshold between benefit and injury due to physical exercise when exposed to air pollution	9
Iso-mukaadial acetate and ursolic acid acetate inhibit the chaperone activity of Plasmodium falciparum heat shock protein 70-1	9
Nutri-stress, mitochondrial dysfunction, and insulin resistance—role of heat shock proteins	9
Astaxanthin supplementation impacts the cellular HSP expression profile during passive heating	9
Gambogic acid and gambogenic acid induce a thiol-dependent heat shock response and disrupt the interaction between HSP90 and HSF1 or HSF2	9
Tanshinone IIA pretreatment promotes cell survival in human lung epithelial cells under hypoxia via AP-1-Nrf2 transcription factor	9
Hsp90 chaperone code and the tumor suppressor VHL cooperatively regulate the mitotic checkpoint	9
The effect of tropisetron on oxidative stress, SIRT1, FOXO3a, and claudin-1 in the renal tissue of STZ-induced diabetic rats	9