OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Psychiatry is 76. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Integration of valence and conflict processing through cellular-field interactions in human subgenual cingulate during emotional face processing in treatment-resistant depression	596
Neurophysiological correlates of ketamine-induced dissociative state in bipolar disorder: insights from real-world clinical settings	512
Correction: Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pa	490
Activation of β2-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms	392
Divergent time-varying connectivity of thalamic sub-regions characterizes clinical phenotypes and cognitive status in multiple sclerosis	355
Mediating and moderating effects of plasma proteomic biomarkers on the association between poor oral health problems and brain white matter microstructural integrity: the UK Biobank study	332
Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach	304
Quantitative magnetization transfer and g-ratio imaging of white matter myelin in early psychotic spectrum disorders	263
Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP	212
Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders	194
The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder	189
Rare copy number variation in posttraumatic stress disorder	183
5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA	165
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures	159
Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful extinction of fear	159
NLRP3-mediated trained immunity of microglia is involved in the recurrence-like episode of depressive disorders	157
Multivariate patterns linking brain microstructure to temperament and behavior in adolescent eating disorders	145
CLN5 deficiency impairs glucose uptake and uncovers PHGDH as a potential biomarker in Batten disease	136
Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response	132
Electric field distribution models in ECT research	131
Psychedelics, psychosis, and the elusive notion of safety	131
Structure-function relationships of the disease-linked A218T oxytocin receptor variant	128
Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear	126
Abatacept inhibits Th17 differentiation and mitigates α-synuclein-induced dopaminergic dysfunction in mice	125
Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health	124

Maternal stressors disrupt mouse placental proteome and fetal brain development in a sex-specific fashion through inflammation and oxidative stress	124
The role of PPAR-γ in memory deficits induced by prenatal and lactation alcohol exposure in mice	122
Unconsidered issues of measurement noninvariance in biological psychiatry: A focus on biological phenotypes of psychopathology	121
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk	120
MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention	120
Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure	118
Global and local ancestry modulate APOE association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample	115
Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization	114
Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility	112
Crif1 deficiency in dopamine neurons triggers early-onset parkinsonism	111
Melatonin: A potential nighttime guardian against Alzheimer’s	110
Widespread choroid plexus contamination in sampling and profiling of brain tissue	110
Aberrant impulse control circuitry in obesity	107
Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons	104
Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons	103
The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology	102
Neurobiological subtypes of adolescent depression: a multimodal integration of morphometric similarity network and spatial transcriptomics	100
Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters	100
Maternal COVID-19 infection associated with offspring neurodevelopmental disorders	99
Inactivation of hypocretin receptor-2 signaling in dopaminergic neurons induces hyperarousal and enhanced cognition but impaired inhibitory control	99
Dynorphin / kappa-opioid receptor regulation of excitation-inhibition balance toggles afferent control of prefrontal cortical circuits in a pathway-specific manner	99
Transcriptomic pathology of neocortical microcircuit cell types across psychiatric disorders	99
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome	97
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity	96
Shared genetic basis between reproductive behaviors and anxiety-related disorders	95
Transcriptomic and epigenomic consequences of heterozygous loss-of-function mutations in AKAP11, a shared risk gene for bipolar disorder and schizophrenia	95
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia	95
Microbial infection promotes amyloid pathology in a mouse model of Alzheimer’s disease via modulating γ-secretase	94
Negative allosteric modulation of mGlu7 disrupts fear memory reconsolidation and glutamatergic signaling in rat and human brain tissue	94
Neurocognitive effects of stress: a metaparadigm perspective	93
Enhancing GluN2A-type NMDA receptors impairs long-term synaptic plasticity and learning and memory	93
Hyperactivity of subicular parvalbumin interneurons drives early amyloid pathology and cognitive deficits in Alzheimer’s disease	92
Changes in cerebral connectivity and brain tissue pulsations with the antidepressant response to an equimolar mixture of oxygen and nitrous oxide: an MRI and ultrasound study	92
Multi-polygenic score prediction of mathematics, reading, and language abilities independent of general cognitive ability	90
Crosstalk between alcohol use disorder and obesity: two sides of the same coin?	90
Mitochondrial health index correlates with plasma circulating cell-free mitochondrial DNA in bipolar disorder	88
Transcriptomic profiles in major depressive disorder: the role of immunometabolic and cell-cycle-related pathways in depression with different levels of inflammation	87
Sex differences in trajectories of cortical development in autistic children from 2–13 years of age	87
Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer’s disease through potentiating the function of extrasynaptic glycine receptors	86
Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment	86
A burden of rare copy number variants in obsessive-compulsive disorder	85
What genes are differentially expressed in individuals with schizophrenia? A systematic review	85
Rare coding variants as risk modifiers of the 22q11.2 deletion implicate postnatal cortical development in syndromic schizophrenia	84
Tractography-based versus anatomical landmark-based targeting in vALIC deep brain stimulation for refractory obsessive-compulsive disorder	83
Age-related vulnerability of the human brain connectome	83
Stress-induced dysfunction of neurovascular astrocytes in the prefrontal cortex contributes to sex-dependent deficits in cognition and behavior	83
Are behavioural and inflammatory profiles different according to type of stressor, developmental stage, and sex in rodent models of depression? A systematic review	82
The genetics of neurodegenerative diseases is the genetics of age-related damage clearance failure	81
Serotonin effects on human iPSC-derived neural cell functions: from mitochondria to depression	78
Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer’s disease	76

Evaluation of Nav1.8 as a therapeutic target for Pitt Hopkins Syndrome