OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Psychiatry is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters	680
Psychedelics, psychosis, and the elusive notion of safety	504
Mediating and moderating effects of plasma proteomic biomarkers on the association between poor oral health problems and brain white matter microstructural integrity: the UK Biobank study	468
Correction: Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pa	285
Crif1 deficiency in dopamine neurons triggers early-onset parkinsonism	234
Maternal COVID-19 infection associated with offspring neurodevelopmental disorders	215
Associations between mosaic loss and schizophrenia or bipolar disorder of young age	193
NLRP3-mediated trained immunity of microglia is involved in the recurrence-like episode of depressive disorders	177
Rare coding variants as risk modifiers of the 22q11.2 deletion implicate postnatal cortical development in syndromic schizophrenia	176
The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder	173
Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization	167
Rare copy number variation in posttraumatic stress disorder	162
Microglia shape AgRP neuron postnatal development via regulating perineuronal net plasticity	159
ASD mutations in the ciliary gene CEP41 impact development of projection neurons and interneurons in a human cortical organoid model	157
Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP	145
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome	143
Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons	141
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia	139
Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders	137
Stress-induced dysfunction of neurovascular astrocytes in the prefrontal cortex contributes to sex-dependent deficits in cognition and behavior	136
Gene dosage effects of 22q11.2 copy number variants on in-vivo measures of white matter axonal density and dispersion	136
Negative allosteric modulation of mGlu7 disrupts fear memory reconsolidation and glutamatergic signaling in rat and human brain tissue	133
Activation of β2-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms	132
Changes in cerebral connectivity and brain tissue pulsations with the antidepressant response to an equimolar mixture of oxygen and nitrous oxide: an MRI and ultrasound study	128
Multi-polygenic score prediction of mathematics, reading, and language abilities independent of general cognitive ability	127

Microbial infection promotes amyloid pathology in a mouse model of Alzheimer’s disease via modulating γ-secretase	127
Inactivation of hypocretin receptor-2 signaling in dopaminergic neurons induces hyperarousal and enhanced cognition but impaired inhibitory control	122
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures	122
Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach	122
The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk	121
The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology	118
Computational mechanisms of learning and forgetting differentiate affective and substance use disorders	115
Transcriptomic profiles in major depressive disorder: the role of immunometabolic and cell-cycle-related pathways in depression with different levels of inflammation	114
Depression in neurodegenerative disease: neurobiological mechanisms and emerging treatments	114
Mitochondrial health index correlates with plasma circulating cell-free mitochondrial DNA in bipolar disorder	113
“Increasing dopamine synthesis capacity in the dorsal striatum and tonic acetylcholine: implications for the new muscarinic agents in the treatment of schizophrenia”	112
Dynorphin / kappa-opioid receptor regulation of excitation-inhibition balance toggles afferent control of prefrontal cortical circuits in a pathway-specific manner	112
5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA	110
Neurobiological subtypes of adolescent depression: a multimodal integration of morphometric similarity network and spatial transcriptomics	110
Exploring the impact of cognitive profiles on the response to magnetic seizure therapy and electroconvulsive therapy	110
Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment	109
Transcriptomic pathology of neocortical microcircuit cell types across psychiatric disorders	108
Neurophysiological correlates of ketamine-induced dissociative state in bipolar disorder: insights from real-world clinical settings	106
Neurocognitive effects of stress: a metaparadigm perspective	106
Abatacept inhibits Th17 differentiation and mitigates α-synuclein-induced dopaminergic dysfunction in mice	104
Sex differences in trajectories of cortical development in autistic children from 2–13 years of age	102
CLN5 deficiency impairs glucose uptake and uncovers PHGDH as a potential biomarker in Batten disease	101
Maternal stressors disrupt mouse placental proteome and fetal brain development in a sex-specific fashion through inflammation and oxidative stress	100
Quantitative magnetization transfer and g-ratio imaging of white matter myelin in early psychotic spectrum disorders	99
Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response	98
Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health	97
Multivariate patterns linking brain microstructure to temperament and behavior in adolescent eating disorders	97
Global and local ancestry modulate APOE association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample	91
Hyperactivity of subicular parvalbumin interneurons drives early amyloid pathology and cognitive deficits in Alzheimer’s disease	87
Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer’s disease through potentiating the function of extrasynaptic glycine receptors	85
Crosstalk between alcohol use disorder and obesity: two sides of the same coin?	84
Integration of valence and conflict processing through cellular-field interactions in human subgenual cingulate during emotional face processing in treatment-resistant depression	83
MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention	82
Transcriptomic and epigenomic consequences of heterozygous loss-of-function mutations in AKAP11, a shared risk gene for bipolar disorder and schizophrenia	82
Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure	82
Tractography-based versus anatomical landmark-based targeting in vALIC deep brain stimulation for refractory obsessive-compulsive disorder	81
Melatonin: A potential nighttime guardian against Alzheimer’s	81
Fever-like temperatures improve cognitive deficits in the Scn2a autism mouse model via increases in potassium channel activity	80
A burden of rare copy number variants in obsessive-compulsive disorder	80
Age-related vulnerability of the human brain connectome	79
The role of PPAR-γ in memory deficits induced by prenatal and lactation alcohol exposure in mice	79
Evaluation of Nav1.8 as a therapeutic target for Pitt Hopkins Syndrome	78
A higher dysregulation burden of brain DNA methylation in female patients implicated in the sex bias of Schizophrenia	77
Robust and replicable functional brain signatures of 22q11.2 deletion syndrome and associated psychosis: a deep neural network-based multi-cohort study	76
Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer’s disease	76
De novo protein-coding gene variants in developmental stuttering	76
Bcl11a deficiency in cerebellar Purkinje cells causes ataxia and autistic-like behavior by altering Vav3	75
Deep learning algorithms reveal genomic markers for anxiety disorder in a large cohort of children with down syndrome	75
Multimodal microglial and kynurenine pathway alterations across the affective-psychosis spectrum: a systematic review of patterns, heterogeneity, and dimensional implications	74
A transcriptional program associated with neurotransmission in the living human brain	74