OOIR: Observatory of International Research

Papers

(The H4-Index of Cytokine & Growth Factor Reviews is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Editorial Board	147
Potential effects of HMGB1 on viral replication and virus infection-induced inflammatory responses: A promising therapeutic target for virus infection-induced inflammatory diseases	139
COVID-19: From emerging variants to vaccination	119
COVID-19 as a mediator of interferon deficiency and hyperinflammation: Rationale for the use of JAK1/2 inhibitors in combination with interferon	114
Unveiling cytokine charge disparity as a potential mechanism for immune regulation	112
Targeting the metabolism and immune system in pancreatic ductal adenocarcinoma: Insights and future directions	96
Navigating IL-6: From molecular mechanisms to therapeutic breakthroughs	94
Macrophage-derived cytokines in pneumonia: Linking cellular immunology and genetics	79
Proteomics analysis of circulating small extracellular vesicles: Focus on the contribution of EVs to tumor metabolism	76
Insights into IL-6/JAK/STAT3 signaling in the tumor microenvironment: Implications for cancer therapy	75
Editorial Board	74
Editorial Board	67
Editorial Board	67
CDK4/6 inhibition in hormone receptor-positive/HER2-negative breast cancer: Biological and clinical aspects	65
Progranulinopathy: A diverse realm of disorders linked to progranulin imbalances	63
Participation of interferons in psoriatic inflammation	63
Molecular mechanisms of regulation of IL-1 and its receptors	60
Epithelial-to-mesenchymal transition transcription factors: New strategies for mesenchymal tissue regeneration	59
Immuno-metabolic control of the balance between Th17-polarized and regulatory T-cells during HIV infection	58
Gradients in the in vivo intestinal stem cell compartment and their in vitro recapitulation in mimetic platforms	54
The immunosuppressive and pro-tumor functions of CCL18 at the tumor microenvironment	52
Central role of Galectin-3 at the cross-roads of cardiac inflammation and fibrosis: Implications for heart failure and transplantation	51
TGF-β mediated drug resistance in solid cancer	51
Pro-angiogenic activity and vasculogenic mimicry in the tumor microenvironment by leptin in cancer	47
Novel insights into neuroinflammatory mechanisms in traumatic brain injury: Focus on pattern recognition receptors as therapeutic targets	46

Asprosin, a novel pleiotropic adipokine implicated in fasting and obesity-related cardio-metabolic disease: Comprehensive review of preclinical and clinical evidence	45
Exogenous drug-induced mouse models of atopic dermatitis	45
Current utilization of interferon alpha for the treatment of coronavirus disease 2019: A comprehensive review	44
Chemokines and chemokine receptors: Insights from human disease and experimental models of helminthiasis	43
Principles of the activin receptor signaling pathway and its inhibition	43
Immunosuppressive tumor microenvironment and uterine fibroids: Role in collagen synthesis	41
The cGAS-STING pathway: Post-translational modifications and functional implications in diseases	40
Scarless wound healing: Current insights from the perspectives of TGF-β, KGF-1, and KGF-2	38
Suppressor of cytokine signaling 6 in cancer development and therapy: Deciphering its emerging and suppressive roles	38
COVID-19 and dys-regulation of pulmonary endothelium: implications for vascular remodeling	37
Tumor microenvironment, histone modifications, and myeloid-derived suppressor cells	37
MDSCs might be “Achilles heel” for eradicating CSCs	36
Exosomes as a modulator of immune resistance in human cancers	36