OOIR: Observatory of International Research

Papers

(The H4-Index of Cytokine & Growth Factor Reviews is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Editorial Board	165
Targeting the metabolism and immune system in pancreatic ductal adenocarcinoma: Insights and future directions	141
COVID-19 as a mediator of interferon deficiency and hyperinflammation: Rationale for the use of JAK1/2 inhibitors in combination with interferon	123
Potential effects of HMGB1 on viral replication and virus infection-induced inflammatory responses: A promising therapeutic target for virus infection-induced inflammatory diseases	123
COVID-19: From emerging variants to vaccination	110
Unveiling cytokine charge disparity as a potential mechanism for immune regulation	106
Navigating IL-6: From molecular mechanisms to therapeutic breakthroughs	89
CDK4/6 inhibition in hormone receptor-positive/HER2-negative breast cancer: Biological and clinical aspects	86
Editorial Board	84
Editorial Board	77
Editorial Board	71
Proteomics analysis of circulating small extracellular vesicles: Focus on the contribution of EVs to tumor metabolism	71
Insights into IL-6/JAK/STAT3 signaling in the tumor microenvironment: Implications for cancer therapy	69
Metabolic Regulation of cGAS-STING Signaling in the Tumor Microenvironment: Dual Immune Roles and Therapeutic Implications	67
Participation of interferons in psoriatic inflammation	65
Progranulinopathy: A diverse realm of disorders linked to progranulin imbalances	62
Cytokine symphony: Deciphering the tumor microenvironment and metastatic axis in oral cancer	56
Epithelial-to-mesenchymal transition transcription factors: New strategies for mesenchymal tissue regeneration	55
Molecular mechanisms of regulation of IL-1 and its receptors	52
The immunosuppressive and pro-tumor functions of CCL18 at the tumor microenvironment	51
Immuno-metabolic control of the balance between Th17-polarized and regulatory T-cells during HIV infection	50
Gradients in the in vivo intestinal stem cell compartment and their in vitro recapitulation in mimetic platforms	50
Pro-angiogenic activity and vasculogenic mimicry in the tumor microenvironment by leptin in cancer	50
Novel insights into neuroinflammatory mechanisms in traumatic brain injury: Focus on pattern recognition receptors as therapeutic targets	47
Central role of Galectin-3 at the cross-roads of cardiac inflammation and fibrosis: Implications for heart failure and transplantation	47

Exogenous drug-induced mouse models of atopic dermatitis	46
Asprosin, a novel pleiotropic adipokine implicated in fasting and obesity-related cardio-metabolic disease: Comprehensive review of preclinical and clinical evidence	44
TGF-β mediated drug resistance in solid cancer	44
Suppressor of cytokine signaling 6 in cancer development and therapy: Deciphering its emerging and suppressive roles	43
Current utilization of interferon alpha for the treatment of coronavirus disease 2019: A comprehensive review	43
Principles of the activin receptor signaling pathway and its inhibition	41
The cGAS-STING pathway: Post-translational modifications and functional implications in diseases	39
Chemokines and chemokine receptors: Insights from human disease and experimental models of helminthiasis	39
Immunosuppressive tumor microenvironment and uterine fibroids: Role in collagen synthesis	38
Scarless wound healing: Current insights from the perspectives of TGF-β, KGF-1, and KGF-2	37
Tumor microenvironment, histone modifications, and myeloid-derived suppressor cells	36
MDSCs might be “Achilles heel” for eradicating CSCs	36
Exosomes as a modulator of immune resistance in human cancers	36
COVID-19 and dys-regulation of pulmonary endothelium: implications for vascular remodeling	36
Exosomes: Another intercellular lipometabolic communication mediators in digestive system neoplasms?	36