Cytokine & Growth Factor Reviews

Papers
(The median citation count of Cytokine & Growth Factor Reviews is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Editorial Board165
Targeting the metabolism and immune system in pancreatic ductal adenocarcinoma: Insights and future directions141
Potential effects of HMGB1 on viral replication and virus infection-induced inflammatory responses: A promising therapeutic target for virus infection-induced inflammatory diseases123
COVID-19 as a mediator of interferon deficiency and hyperinflammation: Rationale for the use of JAK1/2 inhibitors in combination with interferon123
COVID-19: From emerging variants to vaccination110
Unveiling cytokine charge disparity as a potential mechanism for immune regulation106
Navigating IL-6: From molecular mechanisms to therapeutic breakthroughs89
CDK4/6 inhibition in hormone receptor-positive/HER2-negative breast cancer: Biological and clinical aspects86
Editorial Board84
Editorial Board77
Proteomics analysis of circulating small extracellular vesicles: Focus on the contribution of EVs to tumor metabolism71
Editorial Board71
Insights into IL-6/JAK/STAT3 signaling in the tumor microenvironment: Implications for cancer therapy69
Metabolic Regulation of cGAS-STING Signaling in the Tumor Microenvironment: Dual Immune Roles and Therapeutic Implications67
Participation of interferons in psoriatic inflammation65
Progranulinopathy: A diverse realm of disorders linked to progranulin imbalances62
Cytokine symphony: Deciphering the tumor microenvironment and metastatic axis in oral cancer56
Epithelial-to-mesenchymal transition transcription factors: New strategies for mesenchymal tissue regeneration55
Molecular mechanisms of regulation of IL-1 and its receptors52
The immunosuppressive and pro-tumor functions of CCL18 at the tumor microenvironment51
Gradients in the in vivo intestinal stem cell compartment and their in vitro recapitulation in mimetic platforms50
Pro-angiogenic activity and vasculogenic mimicry in the tumor microenvironment by leptin in cancer50
Immuno-metabolic control of the balance between Th17-polarized and regulatory T-cells during HIV infection50
Novel insights into neuroinflammatory mechanisms in traumatic brain injury: Focus on pattern recognition receptors as therapeutic targets47
Central role of Galectin-3 at the cross-roads of cardiac inflammation and fibrosis: Implications for heart failure and transplantation47
Exogenous drug-induced mouse models of atopic dermatitis46
Asprosin, a novel pleiotropic adipokine implicated in fasting and obesity-related cardio-metabolic disease: Comprehensive review of preclinical and clinical evidence44
TGF-β mediated drug resistance in solid cancer44
Current utilization of interferon alpha for the treatment of coronavirus disease 2019: A comprehensive review43
Suppressor of cytokine signaling 6 in cancer development and therapy: Deciphering its emerging and suppressive roles43
Principles of the activin receptor signaling pathway and its inhibition41
Chemokines and chemokine receptors: Insights from human disease and experimental models of helminthiasis39
The cGAS-STING pathway: Post-translational modifications and functional implications in diseases39
Immunosuppressive tumor microenvironment and uterine fibroids: Role in collagen synthesis38
Scarless wound healing: Current insights from the perspectives of TGF-β, KGF-1, and KGF-237
Exosomes: Another intercellular lipometabolic communication mediators in digestive system neoplasms?36
Tumor microenvironment, histone modifications, and myeloid-derived suppressor cells36
MDSCs might be “Achilles heel” for eradicating CSCs36
Exosomes as a modulator of immune resistance in human cancers36
COVID-19 and dys-regulation of pulmonary endothelium: implications for vascular remodeling36
Multifaceted role of CD14 in innate immunity and tissue homeostasis34
Quantitative and qualitative differences in the activation of a fibroblast growth factor receptor by different FGF ligands33
Editorial Board33
B cell-activating factor and its targeted therapy in autoimmune diseases32
The roles of cell-cell and organ-organ crosstalk in the type 2 diabetes mellitus associated inflammatory microenvironment31
The IFN-γ/miniTrpRS signaling axis: An insight into the pathophysiology of osteoporosis and therapeutic potential31
Netrin-1: An emerging player in inflammatory diseases30
Exploring inflammatory and fibrotic mechanisms driving diabetic nephropathy progression30
Crosstalk between ferroptosis and the epithelial-mesenchymal transition: Implications for inflammation and cancer therapy29
The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies29
Nuclear translocation of RON receptor tyrosine kinase. New mechanistic and functional insights28
Modulation of IL-33/ST2 signaling as a potential new therapeutic target for cardiovascular diseases28
Decoding the roles of heat shock proteins in liver cancer28
The impact of adipokines on vascular networks in adipose tissue26
Forgetting COVID-19 – Introduction to the special issue26
Therapeutic inhibition of the JAK-STAT pathway in the treatment of inflammatory bowel disease25
Role of exosomes in transferring chemoresistance through modulation of cancer glycolytic cell metabolism24
Liquid biopsy analysis of lipometabolic exosomes in pancreatic cancer24
Extracellular vesicles: Emerging mediators of cell communication in gastrointestinal cancers exhibiting metabolic abnormalities23
Exosomal noncoding RNA-mediated spatiotemporal regulation of lipid metabolism: Implications in immune evasion and chronic inflammation23
Editorial Board22
mTOR in programmed cell death and its therapeutic implications22
The role of Extracellular Vesicles in glycolytic and lipid metabolic reprogramming of cancer cells: Consequences for drug resistance22
Cholecystokinin and gastrin as immune modulating hormones: Implications and applications21
Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders21
Could IL-25 be a potential therapeutic target for intestinal inflammatory diseases?20
Glioblastoma-associated macrophages: A key target in overcoming glioblastoma therapeutic resistance20
Exosomes-regulated lipid metabolism in tumorigenesis and cancer progression20
Ferroptosis in immune cells: Implications for tumor immunity and cancer therapy20
Nefarious NTRK oncogenic fusions in pediatric sarcomas: Too many to Trk20
ALCAM/CD166: A pleiotropic mediator of cell adhesion, stemness and cancer progression20
Alternative pathways driven by STING: From innate immunity to lipid metabolism19
Unraveling the intricacies of neutrophil extracellular traps in inflammatory bowel disease: Pathways, biomarkers, and promising therapies19
JAK inhibitors in immune regulation and treatment of vitiligo19
Crosstalk between lncRNAs in the apoptotic pathway and therapeutic targets in cancer19
Regulation of regulated cell death by extracellular vesicles in acute kidney injury and chronic kidney disease18
The critical role of osteopontin (OPN) in fibrotic diseases18
Uncovering key mechanisms and intervention therapies in aging skin18
Multiple post-translational modifications ensure EGFR functionality: Potential therapeutic targets to overcome its drug-resistance mutations18
The journey of STING: Guiding immune signaling through membrane trafficking18
The role and transformative potential of IL-19 in atherosclerosis18
The IL-2A receptor pathway and its role in lymphocyte differentiation and function18
Mechanisms and routes of G-protein coupled receptor-mediated Tau degradation in Alzheimer’s disease18
Editorial Board17
Cancer-associated fibroblasts: Vital suppressors of the immune response in the tumor microenvironment17
An emerging paradigm of CXCL16 involvement in cancer progression16
The conundrum of current anti-SARS-CoV-2 vaccines16
Macrophage migration inhibitor factor (MIF): Potential role in cognitive impairment disorders16
Decoding the neuroimmune axis in colorectal cancer: From neural circuitry to therapeutic innovation16
The functional roles of m6A modification in T lymphocyte responses and autoimmune diseases16
Antiphospholipid antibodies and risk of post-COVID-19 vaccination thrombophilia: The straw that breaks the camel's back?16
The activin-follistatin system: Key regulator of kidney development, regeneration, inflammation, and fibrosis16
LC3B: A microtubule-associated protein influences disease progression and prognosis16
Leptin as a mechanistic link between obesity and systemic lupus erythematous16
GLP-1R agonist therapy and vaccine response: Neglected implications15
Endothelial and macrophage interactions in the angiogenic niche15
Galectins as modulators of receptor tyrosine kinases signaling in health and disease15
The anti-inflammatory effects of itaconate and its derivatives in neurological disorders14
T cell receptor signaling in the differentiation and plasticity of CD4+ T cells14
Interleukin-33/serum stimulation-2 pathway: Regulatory mechanisms and emerging implications in immune and inflammatory diseases14
FGF/FGFR signaling: From lung development to respiratory diseases14
Exosome-mediated metabolic reprogramming: Implications in esophageal carcinoma progression and tumor microenvironment remodeling14
Retard or exacerbate: Role of long non-coding RNA growth arrest-specific 5 in the fibrosis14
Pharmacological therapies and drug development targeting SARS-CoV-2 infection13
Cytokines on the way to secretion13
Immune evasion of neutralizing antibodies by SARS-CoV-2 Omicron13
Recent progress and prospects for anti-cytokine therapy in preclinical and clinical acute lung injury13
Role of lipid signalling in extracellular vesicles-mediated cell-to-cell communication13
The central role of CXCL10-CXCR3 signaling in neuroinflammation and neuropathology13
Revisiting IRF1-mediated antiviral innate immunity13
Cytokines and soluble mediators as architects of tumor microenvironment reprogramming in cancer therapy13
SARS-CoV-2 infection and oxidative stress: Pathophysiological insight into thrombosis and therapeutic opportunities13
The interleukin-1 cytokine family members: Role in cancer pathogenesis and potential therapeutic applications in cancer immunotherapy12
Glycosylation of FGF/FGFR: An underrated sweet code regulating cellular signaling programs12
The impact of cytokines in neuroinflammation-mediated stroke12
Extracellular vesicles as mediators of cell-cell communication in ovarian cancer and beyond – A lipids focus12
The involvement of TH17 cells in the pathogenesis of IBD12
Assessment of clinical studies evaluating combinations of immune checkpoint inhibitors with locoregional treatments in solid tumors12
The Coronavirus pandemic – 2022: Viruses, variants & vaccines12
Mechanisms of NLRP3 inflammasome activation and the development of peptide inhibitors11
Role of growth factors and their interplay during oligodendroglial differentiation and maturation11
Targeting interleukin-17 in radiation-induced toxicity and cancer progression11
Neuroprotective properties of ciliary neurotrophic factor in the retina for the treatment of macular telangiectasia type 211
The odyssey of cGAS: From cytosol to nucleus11
Preexisting immunity: Barrier or bridge to effective oncolytic virus therapy?10
BCR-ABL: The molecular mastermind behind chronic myeloid leukemia10
Unveiling the role of IL-17: Therapeutic insights and cardiovascular implications10
The role of microglial activation on ischemic stroke: Modulation by fibroblast growth factors10
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