OOIR: Observatory of International Research

Papers

(The H4-Index of Apoptosis is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Succinate-mediated SUCNR1 activation in tumor-associated macrophages promotes M2 polarization and cetuximab resistance in colorectal cancer: in vitro and in vivo insights	413
Disruption of iron homeostasis by HERC2-FTL axis leads to chondrocyte loss and exacerbates osteoarthritis	347
Spatially defined danger zone shapes gastric cancer progression through CCDC80+ fibroblast–induced CD8+ T cell dysfunction	272
N6-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m6A/PD-L1 manner	156
Breast cancer: taxonomy, distribution analysis, risk factors, predictive biomarkers, and modern treatment method	115
An integrated investigation of sulfotransferases (SULTs) in hepatocellular carcinoma and identification of the role of SULT2A1 on stemness	101
Transcription factor EB-mediated autophagy affects cell migration and inhibits apoptosis to promote endometriosis	78
Exosomes derived from FN14-overexpressing BMSCs activate the NF-κB signaling pathway to induce PANoptosis in osteosarcoma	63
Global trends in PANoptosis research: bibliometrics and knowledge graph analysis	61
Programmed cell death lives	61
Molecular probes for monitoring pyroptosis: design, imaging and theranostic application	61
Removing therapy-induced senescent cancer cells targets and potentiates the response of pancreatic cancer cells toward PARP inhibitors as maintenance therapy	59
ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP	56
Monitoring yeast regulated cell death: trespassing the point of no return to loss of plasma membrane integrity	53
Mitophagy: a novel avenue for herbal medicines alleviating myocardial ischemia/reperfusion injury	52
Higher replication potential of West Nile virus governs apoptosis induction in human neuroblastoma cells	51
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak	51
The circTIMP2/miR-106a/TIMP2 tumor-suppressive axis versus tumor-derived exosomal counteraction in gastric cancer	51
Multiple myeloma with high expression of SLC7A11 is sensitive to erastin-induced ferroptosis	50
The STING signaling pathways and bacterial infection	50
Caspase-1 in cancer and inflammatory diseases: a potential therapeutic target	50
Tumor cell-derived exosome RNF126 affects the immune microenvironment and promotes nasopharyngeal carcinoma progression by regulating PTEN ubiquitination	49
The CXCL8-CXCR2 axis promotes M2 macrophage polarization in ovarian cancer via RASGRP4-mediated mTOR-STAT3 signaling	48
The ATG14: multi-layer autophagy control and an emerging therapeutic target in cancer	47
Augmenter of liver regeneration reduces mitochondria-derived ROS and NLRP3 inflammasome activation through PINK1/Parkin-mediated mitophagy in ischemia-reperfusion-induced renal tubular injury	47

LncRNA PVT1 delays skin photoaging by sequestering miR-551b-3p to release AQP3 expression via ceRNA mechanism	47
Research progress on the mechanism of FOXO protein in sepsis	46
Targeting cuproptosis in liver cancer: Molecular mechanisms and therapeutic implications	45
Machine learning-based analysis of programmed cell death types and key genes in intervertebral disc degeneration	45
PTGR1-mediated immune evasion mechanisms in late-stage triple-negative breast cancer: mechanisms of M2 macrophage infiltration and CD8+ T cell suppression	45
Transcriptomic responses of cumulus granulosa cells to SARS-CoV-2 infection during controlled ovarian stimulation	44
A double-edged sword: role of apoptosis repressor with caspase recruitment domain (ARC) in tumorigenesis and ischaemia/reperfusion (I/R) injury	43
LncRNA PVT1 drives macrophage polarization and triple-negative breast cancer progression via PPARγ-mediated transcriptional activation	42
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria	41
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release	41
Regulation of autophagy of the heart in ischemia and reperfusion	40
m6A methyltransferase WTAP regulates myocardial ischemia reperfusion injury through YTHDF1/FOXO3a signaling	40
Dual role of endoplasmic reticulum stress-ATF-6 activation in autophagy and apoptosis induced by cyclic stretch in myoblast	39
An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma	38