Apoptosis

Papers
(The TQCC of Apoptosis is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)
ArticleCitations
Transcription factor EB-mediated autophagy affects cell migration and inhibits apoptosis to promote endometriosis279
Nobiletin as an inducer of programmed cell death in cancer: a review213
ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP170
Monitoring yeast regulated cell death: trespassing the point of no return to loss of plasma membrane integrity150
Molecular probes for monitoring pyroptosis: design, imaging and theranostic application119
Exosomes derived from FN14-overexpressing BMSCs activate the NF-κB signaling pathway to induce PANoptosis in osteosarcoma113
Global trends in PANoptosis research: bibliometrics and knowledge graph analysis82
Programmed cell death, redox imbalance, and cancer therapeutics75
Programmed cell death lives51
N6-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m6A/PD-L1 manner47
An integrated investigation of sulfotransferases (SULTs) in hepatocellular carcinoma and identification of the role of SULT2A1 on stemness45
LncRNA PVT1 delays skin photoaging by sequestering miR-551b-3p to release AQP3 expression via ceRNA mechanism45
Machine learning-based analysis of programmed cell death types and key genes in intervertebral disc degeneration45
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak43
Higher replication potential of West Nile virus governs apoptosis induction in human neuroblastoma cells41
The CXCL8-CXCR2 axis promotes M2 macrophage polarization in ovarian cancer via RASGRP4-mediated mTOR-STAT3 signaling39
Multiple myeloma with high expression of SLC7A11 is sensitive to erastin-induced ferroptosis38
Tumor cell-derived exosome RNF126 affects the immune microenvironment and promotes nasopharyngeal carcinoma progression by regulating PTEN ubiquitination37
Augmenter of liver regeneration reduces mitochondria-derived ROS and NLRP3 inflammasome activation through PINK1/Parkin-mediated mitophagy in ischemia-reperfusion-induced renal tubular injury37
The STING signaling pathways and bacterial infection36
PLAGL2-STAU1-NCOA4 axis enhances gastric cancer peritoneal metastasis by resisting ferroptosis via ferritinophagy35
Necroptosis in myocardial ischaemia-reperfusion injury: current update on mechanisms, therapeutic targets, and translational potential35
m6A methyltransferase WTAP regulates myocardial ischemia reperfusion injury through YTHDF1/FOXO3a signaling35
Dual role of endoplasmic reticulum stress-ATF-6 activation in autophagy and apoptosis induced by cyclic stretch in myoblast34
Transcriptomic responses of cumulus granulosa cells to SARS-CoV-2 infection during controlled ovarian stimulation34
A double-edged sword: role of apoptosis repressor with caspase recruitment domain (ARC) in tumorigenesis and ischaemia/reperfusion (I/R) injury32
Genipin protects against acute liver injury by abrogating ferroptosis via modification of GPX4 and ALOX15-launched lipid peroxidation in mice32
Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release30
An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma29
PTGR1-mediated immune evasion mechanisms in late-stage triple-negative breast cancer: mechanisms of M2 macrophage infiltration and CD8+ T cell suppression29
Regulation of autophagy of the heart in ischemia and reperfusion28
Rising impact of cell death research27
JNK-dependent phosphorylation and nuclear translocation of EGR-1 promotes cardiomyocyte apoptosis27
Activation of the 20S proteasome core particle prevents cell death induced by oxygen- and glucose deprivation in cultured cortical neurons26
Correction: Targeting PNPO to suppress tumor growth via inhibiting autophagic flux and to reverse paclitaxel resistance in ovarian cancer26
Analysis of cuproptosis-related lncRNA signature for predicting prognosis and tumor immune microenvironment in pancreatic cancer26
Novel dual inhibitor targeting CDC25 and HDAC for treating triple-negative breast cancer25
LINC00511 promotes cervical cancer progression by regulating the miR-497-5p/MAPK1 axis25
The role of lncRNA OIP5-AS1 in cancer development and progression25
Bufalin targeting BFAR inhibits the occurrence and metastasis of gastric cancer through PI3K/AKT/mTOR signal pathway24
A ZFP42/MARK2 regulatory network reduces the damage of retinal ganglion cells in glaucoma: a study based on GEO dataset and in vitro experiments24
Exploring the role of ITGB6: fibrosis, cancer, and other diseases24
5-Aminolevulinic acid-mediated photodynamic therapy in combination with kinase inhibitor lapatinib enhances glioblastoma cell death24
Zincoptosis: does it exist?23
Integrative analysis of genes reveals endoplasmic reticulum stress-related immune responses involved in dilated cardiomyopathy with fibrosis23
Overview of genetic and epigenetic regulation of human papillomavirus and apoptosis in cervical cancer23
CHI3L1 promotes myocardial fibrosis via regulating lncRNA TUG1/miR-495-3p/ETS1 axis23
The role of the NcRNA/ferroptosis axis in lung cancer: molecular mechanisms and potential therapeutic targets23
Exosome-mediated triple drug delivery enhances apoptosis in pancreatic cancer cells23
LncRNA ENSMUST_147219 mediates the progression of ischemic acute kidney injury by targeting the miR-221-5p/IRF6 axis23
The critical role of X-linked inhibitor of apoptosis protein (XIAP) in tumor development22
Casein kinase 1α mediates eryptosis: a review22
XIAP as a multifaceted molecule in Cellular Signaling22
CACNA1C-AS2 inhibits cell proliferation and suppresses cell migration and invasion via targeting FBXO45 and PI3K/AKT/mTOR pathways in glioma21
Exploring a specialized programmed-cell death patterns to predict the prognosis and sensitivity of immunotherapy in cutaneous melanoma via machine learning21
The role of TIGIT-CD226-PVR axis in mediating T cell exhaustion and apoptosis in NSCLC20
PANoptosis: a potential new target for programmed cell death in breast cancer treatment and prognosis20
Ferroptosis: a novel therapeutic warrior in the battle against leukemia20
Critical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury20
Live-cell imaging and mathematical analysis of the “community effect” in apoptosis19
Let-7a-5p regulated by lncRNA-MEG3 promotes functional differentiation to Schwann cells from adipose derived stem cells via directly inhibiting RBPJ-mediating Notch pathway19
USP43 impairs cisplatin sensitivity in epithelial ovarian cancer through HDAC2-dependent regulation of Wnt/β-catenin signaling pathway18
Brazilin alleviates acute lung injury via inhibition of ferroptosis through the SIRT3/GPX4 pathway17
Human umbilical cord mesenchymal stem cell-derived exosomes carrying miR-1827 downregulate SUCNR1 to inhibit macrophage M2 polarization and prevent colorectal liver metastasis17
The N6-methyladenosine writer METTL3 promotes breast cancer progression through YTHDF2-dependent posttranscriptional silencing of GSDMD17
The regulation of necroptosis by ubiquitylation16
Correction to: NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis16
EFNA4-enhanced deubiquitination of SLC7A11 inhibits ferroptosis in hepatocellular carcinoma16
Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission16
Cuproptosis identifies respiratory subtype of renal cancer that confers favorable prognosis16
Combined effects of natural products and exercise on apoptosis pathways in obesity-related skeletal muscle dysfunction16
MARCH5 promotes aerobic glycolysis to facilitate ovarian cancer progression via ubiquitinating MPC116
Mechanisms of nucleophosmin (NPM)-mediated regulated cell death elucidated by Hsp70 during renal ischemia16
Anticancer effect and apoptosis induction by azaflavanone derivative in human prostate cancer cells16
Targeting mitochondria as a therapeutic anti-gastric cancer approach16
Stemness-related lncRNAs signature as a biologic prognostic model for head and neck squamous cell carcinoma15
Integrating single-cell sequencing and machine learning to uncover the role of mitophagy in subtyping and prognosis of esophageal cancer15
DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells15
Circ_0000523 regulates miR-1184/COL1A1/PI3K/Akt pathway to promote nasopharyngeal carcinoma progression15
Unveiling the hidden role of disulfidptosis in kidney renal clear cell carcinoma: a prognostic signature for personalized treatment15
The mechanistic study of quercetin in the treatment of alcoholic brain injury via the JNK/P38 MAPK signaling pathway15
SNCA is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients15
TBC1D10B promotes tumor progression in colon cancer via PAK4‑mediated promotion of the PI3K/AKT/mTOR pathway15
Correction to: Integrative analysis of genes reveals endoplasmic reticulum stress-related immune responses involved in dilated cardiomyopathy with fibrosis15
Development and experimental validation of a machine learning-based disulfidptosis-related ferroptosis score for hepatocellular carcinoma14
Is long-term administration of PLD-pegylated liposomal doxorubicin able to induce oral cancer?14
Role of the USP family in autophagy regulation and cancer progression14
IGF2BP3 boosts lactate generation to accelerate gastric cancer immune evasion14
Role of ferroptosis in food-borne mycotoxin-induced toxicities14
Bushen Jianpi Tiaoxue Decoction (BJTD) inhibits the LIF-mTOR signaling axis to regulate mitochondrial function and alleviate cyclophosphamide-induced diminished ovarian reserve14
Ferroptosis crosstalk in anti-tumor immunotherapy: molecular mechanisms, tumor microenvironment, application prospects14
DLD is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients14
Inverse regulation of GSDMD and GSDME gene expression during LPS-induced pyroptosis in RAW264.7 macrophage cells14
Unlocking Parkinson’s disease: the role of microRNAs in regulation, diagnosis, and therapy14
Emerging role of PANoptosis in kidney diseases: molecular mechanisms and therapeutic opportunities14
Prognostic implications and therapeutic opportunities related to CAF subtypes in CMS4 colorectal cancer: insights from single-cell and bulk transcriptomics13
Ochratoxin A-induced mitochondrial pathway apoptosis and ferroptosis by promoting glycolysis13
Terpenoids’ anti-cancer effects: focus on autophagy13
microRNA-205 represses breast cancer metastasis by perturbing the rab coupling protein [RCP]-mediated integrin β1 recycling on the membrane13
DDI2 promotes tumor metastasis and resists antineoplastic drugs-induced apoptosis in colorectal cancer13
GJB2 as a novel prognostic biomarker associated with immune infiltration and cuproptosis in ovarian cancer13
Context-dependent activation of p53 target genes and induction of apoptosis by actinomycin D in aerodigestive tract cancers13
Research progress on the mechanism of curcumin in cerebral ischemia/reperfusion injury: a narrative review13
Benzofuran pyran hybrid prevents glucocorticoid induced osteoporosis in mice via modulation of canonical Wnt/β-catenin signaling13
A new perspective on iron-dependent cell death: PRDX-1-mediated ferroptosis in tumor cells13
Targeting ferroptosis: a novel insight against myocardial infarction and ischemia–reperfusion injuries13
The fundamental contribution of James Maxwell Ross Cormack (1909–1975) in suggesting the term “apoptosis”13
A novel programmed cell death signature predicts clinical outcomes in clear cell renal cell carcinoma and identifies PLK1 as a therapeutic target13
Bibliometric analysis and mini-review of global research on pyroptosis in the field of cancer12
Correction: Atorvastatin inhibits the apoptosis of human umbilical vein endothelial cells induced by angiotensin II via the lysosomalmitochondrial axis12
MLKL and other necroptosis-related genes promote the tumor immune cell infiltration, guiding for the administration of immunotherapy in bladder urothelial carcinoma12
Mild hypothermia alleviates oxygen−glucose deprivation/reperfusion-induced apoptosis by inhibiting ROS generation, improving mitochondrial dysfunction and regulating DNA damage repair pathway in PC12 12
EVA1A reverses lenvatinib resistance in hepatocellular carcinoma through regulating PI3K/AKT/p53 signaling axis12
Intravenous immunoglobulin ameliorates doxorubicin-induced intestinal mucositis by inhibiting the Syk/PI3K/Akt axis and ferroptosis12
Diallyl disulfide in oncotherapy: molecular mechanisms and therapeutic potentials12
IGF2BP2 promotes lncRNA DANCR stability mediated glycolysis and affects the progression of FLT3-ITD + acute myeloid leukemia12
A deadly taste: linking bitter taste receptors and apoptosis12
Bufalin inhibits immune escape in metastatic colorectal cancer by regulating M2 macrophage polarization12
Understanding the mechanistic roles of environmental heavy metal stressors in regulating ferroptosis: adding new paradigms to the links with diseases12
Novel impact of metal ion-induced cell death on diabetic cardiomyopathy pathogenesis and therapy12
0.049649953842163