Critical Care

Article	Citations
What every intensivist needs to know about mpox	585
Volatile anaesthetics for ICU sedation: beyond hypnosis?	584
COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation	325
Family concerns in organ donor conversations: a qualitative embedded multiple-case study	251
Weight-normalized norepinephrine dosing and apparent BMI-dependent vasopressin responsiveness	189
Machine learning models compared with current clinical indices to predict the outcome of high flow nasal cannula therapy in acute hypoxemic respiratory failure	167
Adverse events as key risk factors for in-hospital mortality in intensive care units	156
Sodium azide (NaN3) intoxication, “the man who lived”: potential effective antidote and treatment strategy	149
Extracorporeal versus conventional cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: a secondary analysis of the Prague OHCA trial	146
Host Response Biomarkers for Sepsis in the Emergency Room	139
Video versus direct laryngoscopy in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials	134
Identification of a sub-group of critically ill patients with high risk of intensive care unit-acquired infections and poor clinical course using a transcriptomic score	134
Longitudinal mycological profiling of influenza-associated and COVID-19-associated pulmonary aspergillosis	134
What criteria for neuropronostication: consciousness or ability? The neuro-intensivist’s dilemma	134
SOFA-2 score predicts mortality in pneumonia-associated sepsis: a retrospective cohort study	129
Termination-of-resuscitation rule in the emergency department for patients with refractory out-of-hospital cardiac arrest: a nationwide, population-based observational study	127
Prevalence of long-term decision regret and associated risk factors in a large cohort of ICU surrogate decision makers	124
Care pathways of sepsis survivors: sequelae, mortality and use of healthcare services in France, 2015–2018	123
Early intubation and patient-centered outcomes in septic shock: a secondary analysis of a prospective multicenter study	122
Pyroptosis in sepsis-associated acute kidney injury: mechanisms and therapeutic perspectives	114
A genome-wide association study of survival in patients with sepsis	113
The impact of bronchoscopy on the safety of percutaneous tracheostomy: a randomized controlled trial	105
A clinical guide to non-invasive respiratory support in acute respiratory failure: ventilation settings, technical optimization and clinical indications	100
Advanced respiratory mechanics assessment in mechanically ventilated obese and non-obese patients with or without acute respiratory distress syndrome	97
Mental health sequelae and management in survivors of cardiogenic shock: a nationwide population-based study	92

Publisher Correction: Volatile sedation in critically ill adults undergoing mechanical ventilation: not all sedatives are equivalent, in sustainability!	90
Andexanet alfa versus four-factor prothrombin complex concentrate for the reversal of apixaban- or rivaroxaban-associated intracranial hemorrhage: a propensity score-overlap weighted analysis	90
The impact of extracorporeal membrane oxygenation on the exposure to isavuconazole: a plea for thorough pharmacokinetic evaluation	90
One-year patient outcomes based on lung morphology in acute respiratory distress syndrome: secondary analysis of LIVE trial	89
Feasibility of bedside portable MRI in neonates and children during ECLS	88
Overestimation of driving pressure by the analysis of the conductive pressure during venous-arterial ECMO: Airway Closure or Intrinsic PEEP?	88
The protective effect of apolipoprotein H in paediatric sepsis	86
Blood trauma in veno-venous extracorporeal membrane oxygenation: low pump pressures and low circuit resistance matter	84
Mega-dose sodium ascorbate: a pilot, single-dose, physiological effect, double-blind, randomized, controlled trial	84
The on-call intensivist: a pilot in the storm	83
The association between the presence and burden of periodic discharges and outcome in septic patients: an observational prospective study	82
How symptoms of prolonged grief disorder, posttraumatic stress disorder, and depression relate to each other for grieving ICU families during the first two years of bereavement	82
Effectiveness of targeted post-acute interventions and follow-up services for sepsis survivors: a systematic review	82
A randomized controlled trial of catheters with different tips and lengths for patients requiring continuous renal replacement therapy in intensive care unit	82
Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1	82
Fluid management for sepsis-induced hypotension in patients with advanced chronic kidney disease: a secondary analysis of the CLOVERS trial	81
Severe community-acquired Streptococcus pneumoniae bacterial meningitis: clinical and prognostic picture from the intensive care unit	81
Real-time monitoring of air pathogens in the ICU with biosensors and robots	81
Evaluation of the impact of artificial intelligence-assisted image interpretation on the diagnostic performance of clinicians in identifying endotracheal tube position on plain chest X-ray: a multi-ca	79
Hypothermia versus normothermia in patients with cardiac arrest and shockable rhythm: a secondary analysis of the TTM-2 study	78
Restrictive fluid management with early de-escalation versus usual care in critically ill patients (reduce trial): a feasibility randomized controlled trial	78
qSOFA combined with suPAR for early risk detection and guidance of antibiotic treatment in emergency department: a bit sweet and a bit sour randomized controlled trial	77
Hidden Harlequin syndrome in neonatal and pediatric VA-ECMO	77
Red blood cell transfusion in brain injury: Is it solely a matter of hemoglobin threshold?	76
Response to the Letter by Spurling and Colleagues	75
Scoring system: use and not use from the future to present	75
Haloperidol is not the “one drug fits all” solution in the treatment of delirium	74
Disenchantment: the overstated impact of citrate concentration on accumulation risk	73
Invasive group A streptococcal infections requiring admission to ICU: a nationwide, multicenter, retrospective study (ISTRE study)	70
Clinical features and factors associated with outcomes of antibody-negative autoimmune encephalitis in patients requiring intensive care	70
Outcomes of transplant recipients on ECMO for COVID-19 respiratory failure: an ELSO registry study	70
Predictive factors for severe long-term chronic kidney disease after acute kidney injury requiring renal replacement therapy in critically ill patients: an ancillary study of the ELVIS randomized cont	70
Intravenous methylprednisolone pulse therapy and the risk of in-hospital mortality among acute COVID-19 patients: Nationwide clinical cohort study	70
Effect of corticosteroids on mortality in patients with community-acquired pneumonia	69
Letter to the editor regarding “Structural and functional alteration of the gut microbiomes in ICU staff: a cross-sectional analysis”	69
Network of job demands-resources and depressive symptoms in critical care nurses: a nationwide cross-sectional study	69
Monotherapy versus combination therapy in severe Legionella pneumonia: a multicenter retrospective observational study	68
A novel capnogram analysis to guide ventilation during cardiopulmonary resuscitation: clinical and experimental observations	68
Continuous renal replacement therapy with the adsorptive oXiris filter may be associated with the lower 28-day mortality in sepsis: a systematic review and meta-analysis	68
Diagnostic performance of the recruitment-to-inflation ratio to assess lung recruitability by PEEP in ARDS. a computed tomography study	66
A pleural drainage tube misplaced into the right atrium	66
Microcirculatory alterations in critically ill COVID-19 patients analyzed using artificial intelligence	66
Can carotid artery Doppler variations induced by the end-expiratory occlusion maneuver predict fluid responsiveness in septic shock patients?	66
Assessing risk of respiratory depression following initial phenobarbital loading for severe alcohol withdrawal syndrome	65
Impact of the Japanese clinical practice guidelines for management of sepsis and septic shock (J-SSCG) 2020 on real-world adherence and interhospital variation: a nationwide inpatient database study	65
A soleful insight: shoe dislocation as a marker for severe injuries in car accident victims	65
Oral care for intubated patients in the intensive care unit: examination of bacterial count and microbiota	64
Is comorbidity alone responsible for changes in health-related quality of life among critical care survivors? A purpose-specific review	64
Rethinking post-sepsis syndrome: linking cellular dysfunction to the clinical picture	64
The INTOXICATE study: methodology and preliminary results of a prospective observational study	62

The management of heart failure cardiogenic shock: an international RAND appropriateness panel	62
Hyperoxia during venoarterial ECMO: Culprit or co-variate? A comment from the BLENDER investigators	61
Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia	61
REmoval of cytokines during CArdiac surgery (RECCAS): a randomised controlled trial	61
The contribution of mechanical ventilation to critical illness-associated diaphragm dysfunction: a critical appraisal	61
How I manage differential gas exchange in peripheral venoarterial extracorporeal membrane oxygenation	60
Integrative multi-omics analysis unravels the host response landscape and reveals a serum protein panel for early prognosis prediction for ARDS	59
Subphenotypes in acute kidney injury: a narrative review	59
Towards optimised nutrition therapy after critical illness: a position statement and research framework by the global research initiative on post-intensive care nutrition (GRIP) consortium	59
Proenkephalin A 119–159 predicts early and successful liberation from renal replacement therapy in critically ill patients with acute kidney injury: a post hoc analysis of the ELAIN trial	58
Fluid balance and outcome in cardiac arrest patients admitted to intensive care unit	58
Safety and efficacy of the Seraph® 100 Microbind® Affinity Blood Filter to remove bacteria from the blood stream: results of the first in human study	57
Cardiopulmonary resuscitation duration and favorable neurological outcome after out-of-hospital cardiac arrest: a nationwide multicenter observational study in Japan (the JAAM-OHCA registry)	57
Web-based application for predicting the potential target phenotype for recombinant human thrombomodulin therapy in patients with sepsis: analysis of three multicentre registries	57
Trendelenburg position is a reasonable alternative to passive leg raising for predicting volume responsiveness in mechanically ventilated patients in the ICU	57
Longitudinal assessment of immunoglobulin response and disease progression in critically ill patients with community acquired pneumonia	56
Reconsidering the urea-to-creatinine ratio as a signal of muscle catabolism in patients with cirrhosis	56
Early hyperoxia and 28-day mortality in patients on venoarterial ECMO support for refractory cardiogenic shock: a bicenter retrospective propensity score-weighted analysis	55
Use of an innovative cuff pressure control and subglottic secretions drainage system in COVID-19 ARDS patients undergoing pronation	55
Time course of electrical activity of the diaphragm (EAdi) in the peri extubation period and its role as predictor of extubation failure in difficult to wean patients	55
10 years trends and hospitalization outcomes of non-neonatal tetanus: a large-scale multicenter retrospective study in China	55
Demographics and outcome of Legionella pneumonia in the intensive care unit: a retrospective multicenter cohort study	55
Peri-intubation adverse events and clinical outcomes in emergency department patients: the BARCO study	54
The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review	54
Quantitative analysis of apparent diffusion coefficients to predict neurological prognosis in cardiac arrest survivors: an observational derivation and internal–external validation study	54
Gut-derived immune cells and the gut-lung axis in ARDS	53
Potential bias and misclassification of using continuous cardiac output to identify fluid responsiveness compared to calibrated measurements	52
The glycocalyx as a permeability barrier: basic science and clinical evidence	52
Imatinib treatment improves hyperglycaemic dysregulation in severe COVID-19: a secondary analysis of blood biomarkers in a randomised controlled trial	52
Shedding light on carboxyhaemoglobin in extracorporeal membrane oxygenation	52
Albumin for sepsis-related peripheral tissue hypoperfusion	52
Lack of up-to-date studies and data conversion may lead to biased results: a response to Wang et al	51
Factors associated with adverse haemodynamic events during the STARRT-AKI trial: a post-hoc secondary analysis	51
Lung ultrasound and ARDS: global collaboration is the way to go	51
Tailored strategy for managing post-cardiac-arrest patients using an early stratification tool: a French university hospital experience	51
Beyond concordance: differential prognostic value of SpO2/FiO2 and PaO2/FiO2 ratios in ARDS severity classification	51
Small patients, big gaps: why adult CRRT timing evidence does not translate to children	50
Early sepsis recognition: how difficult can this be?	50
Association of epinephrine and outcome in cardiac arrest with refractory shockable rhythm: a population-based, propensity-score matched analysis	50
The association between time definition of reintubation and patient outcomes in critically ill patients: several topics should be noticed	50
Burden of sepsis in China: a systematic analysis from 1990 to 2021	50
Volume of oxygen administered during mechanical ventilation predicts mortality in ICU patients	49
Elevated serum pre-arrest cathepsin D concentrations are associated with higher mortality in in-hospital cardiac arrest	49
Estimation of transpulmonary driving pressure during synchronized mechanical ventilation using a single lower assist maneuver (LAM) in rabbits: a comparison to measurements made with an esophageal bal	49
Difference of 11 years between two periods of VV-ECMO does not impact mortality in large centres: we are not sure	49
Prevalence and incidence of cognitive impairment following acute respiratory distress syndrome of any cause: a systematic review and meta-analysis	48
Temporal trends in mortality and provision of intensive care in younger women and men with acute myocardial infarction or stroke	48
Effects on health-related quality of life of interventions affecting survival in critically ill patients: a systematic review	48
Letter to the Editor Regarding “Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia: a systematic review and meta-analysis of randomized controlle	48
Trends in survival during the pandemic in patients with critical COVID-19 receiving mechanical ventilation with or without ECMO: analysis of the Japanese national registry data	47
Clinical applications for the endotoxin activity assay in sepsis: a scoping review	47
Correction: Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP) in patients with acute exacerbation of COPD: From the French OUTCOMEREA cohort	47
Strategies for lung- and diaphragm-protective ventilation in acute hypoxemic respiratory failure: a physiological trial	47
Prognostic models for outcome prediction following in-hospital cardiac arrest using pre-arrest factors: a systematic review, meta-analysis and critical appraisal	47
Impact of COVID-19 on posttraumatic stress disorder in ICU survivors: a prospective observational comparative cohort study	47
External validation of the modified sepsis renal angina index for prediction of severe acute kidney injury in children with septic shock	46
Extracellular vesicles as biomarkers in traumatic brain injury: a systematic review of animal and clinical studies	46
Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation	46
Liberal transfusion strategies reduce sepsis risk and improve neurological recovery in acute brain injury: an updated systematic review and meta-analysis	45
Temperature control after cardiac arrest	45
Transforming research to improve therapies for trauma in the twenty-first century: an alternative perspective	45
Association between early nutrition support and 28-day mortality in critically ill patients: the FRANS prospective nutrition cohort study	45
Based -evidence, an intervention study to improve sleep quality in awake adult ICU patients: a prospective, single-blind, clustered controlled trial	45
A multicentre prospective registry of one thousand sepsis patients admitted in Indian ICUs: (SEPSIS INDIA) study	44
Sepsis-induced hypocholesterolemia is linked to low cardiomyocyte membrane cholesterol and impaired catecholamine responsiveness	44
Roadmap for the evolution of monitoring: developing and evaluating waveform-based variability-derived artificial intelligence-powered predictive clinical decision support software tools	44
Consensus statement from the 2025 Delphi panel on cerebral microdialysis in critical care	44
In-hospital mortality of patients admitted to the intermediate care unit in hospitals with and without an intensive care unit: a nationwide inpatient database study	44
Prehospital extracorporeal cardiopulmonary resuscitation in refractory out-of-hospital cardiac arrest: retrospective eligibility verification should not be conflated with prospective triage performanc	44
Acute kidney injury after out-of-hospital cardiac arrest	44
Association between cholinesterase activity and critical illness brain dysfunction	43
Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis	43
Noninvasive neuromodulation for disorders of consciousness: an updated systematic review and meta-analysis	43
Use of extracorporeal blood purification therapies in sepsis: the current paradigm, available evidence, and future perspectives	43
Respiratory challenges and ventilatory management in different types of acute brain-injured patients	43
Prospective, multicenter validation of the deep learning-based cardiac arrest risk management system for predicting in-hospital cardiac arrest or unplanned intensive care unit transfer in patients adm	43
Incidence, kinetics, and clinical impact of thrombocytopenia in venovenous ECMO: insights from the multicenter observational PROTECMO study	42
PSP is a promising biomarker of sepsis; however, potential elimination by RRT must be considered	42
Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction	42
Vitamin K: a potential missing link in critical illness–a scoping review	42

Confused with confounders? Understanding the role of directed acyclic graphs in observational research	42
Hospital change to mixed lipid emulsion from soybean oil-based lipid emulsion for parenteral nutrition in hospitalized and critically ill adults improves outcomes: a pre–post-comparative study	42
Trends in mortality in septic patients according to the different organ failure during 15 years	42
Improving frailty assessment: the task is not finished	42
Endotoxin hemoadsorption in refractory septic shock with multiorgan dysfunction and extreme endotoxin activity	41
Spontaneous diuresis in combination with furosemide stress test (SD-FST) as predictor for successful liberation from kidney replacement therapy: a prospective observational study	41
Lactate regulation may be a key factor in the protection of the intestinal barrier in sepsis under high-altitude hypoxic and hypobaric conditions	41
Early trajectories of pulmonary hemodynamics in ARDS patients undergoing V-V ECMO: key determinants and prognostic impact	40
Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study	40
Personalised PEEP that yields the highest lung compliance versus optimal balance between overdistension and collapse during PSV: authors’ reply to Dr Stenqvist	40
Tocilizumab in treating children with refractory septic shock	40
From indication to initiation of invasive intracranial pressure monitoring time differences between neurosurgeons and intensive care physicians: can intracranial hypertension dose be reduced? TIMING-I	40
Covid-19 associated ARDS in pregnant women and timing of delivery: a single center experience	40
Incidence, risk factors and outcomes of nosocomial infection in adult patients supported by extracorporeal membrane oxygenation: a systematic review and meta-analysis	40
Discovery of a resistant cohort to acute kidney injury: insights from patients with septic shock	40
Sepsis mortality among patients with haematological malignancy admitted to intensive care 2000–2022: a binational cohort study	39
Expert clinical pharmacological advice may make an antimicrobial TDM program for emerging candidates more clinically useful in tailoring therapy of critically ill patients	39
Intraosseous catheter confirmation with central venous color flow and doppler waveform, a randomized single-blinded trial	39
Peri-intubation complications in critically ill obese patients: a secondary analysis of the international INTUBE cohort	38
Urinary urea excretion index to guide weaning from renal replacement therapy in patients with acute kidney injury: Still haven’t found what i’m weaning for	38
Transitions of blood immune endotypes and improved outcome by anakinra in COVID-19 pneumonia: an analysis of the SAVE-MORE randomized controlled trial	38
Enhanced exclusive enteral nutrition delivery during the first 7 days is associated with decreased 28-day mortality in critically ill patients with normal lactate level: a post hoc analysis of a multi	38
Understanding and addressing a ‘difficult’ family in ICU	38
Reexamining cholinesterase inhibitors for the prevention and treatment of delirium in high-risk populations	38
Clinical and biological features of CMV reactivation in ARDS: a prospective cohort study	38
Time to positivity as a predictor of catheter-related bacteremia and mortality in adults with Pseudomonas aeruginosa bloodstream infection	37
Spontaneous pneumomediastinum: a surrogate of P-SILI in critically ill COVID-19 patients	37
Inflammation and altered metabolism impede efficacy of functional electrical stimulation in critically ill patients	37
Intravenous vitamin C in adults with sepsis in the intensive care unit: still LOV’IT?	37
A critical reappraisal of vasopressin and steroids in in-hospital cardiac arrest	37
Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial	36
Use of extracorporeal membrane oxygenation in adult trauma patients with refractory acute cardiopulmonary failure: guideline from the Chinese society of extracorporeal life support 2025	36
Comparative effectiveness of alternative spontaneous breathing trial techniques: a systematic review and network meta-analysis of randomized trials	36
Reversible skin microvascular hyporeactivity in patients with immune-mediated thrombocytopenic thrombotic purpura	36
Corticosteroids and community-acquired pneumonia: Africa deserves an explanatory trial	36
Streamlining data recording through optical character recognition: a prospective multi-center study in intensive care units	36
Fluid responsiveness and changes in venous congestion and lung water during volume expansion in critically ill patients: a multicentre observational study	36
Meta-analysis of pulse pressure variation (PPV) and stroke volume variation (SVV) studies: a few rotten apples can spoil the whole barrel	36
Methylene blue as adjunctive therapy in septic shock: correct drug diluent derives optimal efficacy	36
Out-of-hospital cardiac arrest in children: an epidemiological study based on the German Resuscitation Registry identifying modifiable factors for return of spontaneous circulation	35
Attenuated hemodynamic response to adjunct vasopressin in obese septic shock patients: a physiological or dose-dependent effect?	35
Cardiovascular effects of lactate in healthy adults: d-lactate, the forgotten enantiomer—authors' reply	35
Effects of different respiratory training methods on respiratory function in patients with spinal cord injury: a network meta-analysis of randomized controlled trials	35
Tidal lung hysteresis to interpret PEEP-induced changes in compliance in ARDS patients	35
Prevalence and prognostic value of preexisting sarcopenia in patients with mechanical ventilation: a systematic review and meta-analysis	35
Effects of a multilevel intervention of resistance training with or without beta-hydroxy-beta-methylbutyrate in medical ICU patients during entire hospitalisation: a four-arm multicentre randomised co	35
Impact of oxygen and carbon dioxide levels on mortality in moderate to severe traumatic brain injury: a systematic review and meta-analysis	34
Clinical validation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections in ICU practice: a promising diagnostic tool	34
A systematic meta-review of interventions to prevent and manage delirium in the Intensive Care Unit: Part 2 – Non-pharmacological and multicomponent interventions	34
Parameters associated with successful weaning of veno-arterial extracorporeal membrane oxygenation: a systematic review	34
Can we reliably use pulse pressure as a surrogate for stroke volume? Physiological background and potential clinical implications for shock resuscitation	34
Toxicities, intensive care management, and outcome of chimeric antigen receptor T cells in adults: an update	34
Pupillary dysfunction during hypothermic circulatory arrest: insights from automated pupillometry	33
Extracorporeal cardiopulmonary resuscitation versus conventional CPR in cardiac arrest: be aware of the temporal selection bias	33
The future of intensive care: delirium should no longer be an issue	33
Effects of airway pressure release ventilation on lung physiology assessed by electrical impedance tomography in patients with early moderate-to-severe ARDS	33
Dynamic change of PaO2 may affect the association between hyperoxemia and prognosis	33
Predictive enrichment using biomarkers in studies of critically-ill patients with sepsis: a systematic review	33
A user evaluation of speech/phrase recognition software in critically ill patients: a DECIDE-AI feasibility study	33
Low levels of small HDL particles predict but do not influence risk of sepsis	33
Study claiming target in sepsis with erythromycin has no effect upon mortality and secondary outcomes includes patients with CRRT and RRT	33
Pitfall of lung ultrasound in the quantification of pneumothorax	33
Prompt antimicrobial therapy and source control on survival and defervescence of adults with bacteraemia in the emergency department: the faster, the better	33
Circular material flow of medication in the intensive care unit	32
Harmful effects of propofol? The Editor’s standpoint	32
Practical considerations on hypoxemia and hypoxia in V-V ECMO patients	32
Are we ready to think differently about setting PEEP?	32
Sodium-glucose co-transporter-2 inhibitors in the intensive care unit setting: do we really need sodium increase, especially in sepsis? Reply	32
Comparison of mechanical versus manual cardiopulmonary resuscitation in cardiac arrest	32
Early norepinephrine in septic shock: are we treating physiology or system efficiency?	32
Doppler study of portal vein and renal venous velocity predict the appropriate fluid response to diuretic in ICU: a prospective observational echocardiographic evaluation	31
Association between acute kidney injury and delirium in critically ill patients: a retrospective cohort study using two independent databases	31
Epidemiology and outcomes of septic shock in Thai children: a nationwide retrospective study from 2015 to 2022	31
Optimal antibiotic use in the intensive care unit	31
Unlocking survival in traumatic cardiac arrest: global insights, innovations, and unmet needs	31
Critical Illness Weakness, Polyneuropathy and Myopathy: Diagnosis, treatment, and long-term outcomes	31
The lower limit margin: a determinant of autoregulatory sensitivity to changes in cerebral perfusion pressure	31
Image augmentation and automated measurement of endotracheal-tube-to-carina distance on chest radiographs in intensive care unit using a deep learning model with external validation	31
Transforming research to improve therapies for trauma in the twenty-first century	31
Critical care outcomes in decompensated cirrhosis: a United States national inpatient sample cross-sectional study	31
Impairment of neutrophil functions and homeostasis in COVID-19 patients: association with disease severity	31
Ventricular septum curvature ratio: a novel imaging marker to predict clinical deterioration in normotensive acute pulmonary embolism	31
Cytomegalovirus reactivation in the lower respiratory tract as an independent risk factor for mortality in critically Ill patients	31
Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure	30
Factors affecting voriconazole pharmacokinetic variability in critically ill patients: a systematic review	30
Advanced serial analysis of the diaphragm surface EMG: insights into the effect of pressure support on the neuro-ventilatory response during the ICU stay	30
Urinary proteomics identifies distinct immunological profiles of sepsis associated AKI sub-phenotypes	30
Development and validation of the tic score for early detection of traumatic coagulopathy upon hospital admission: a cohort study	30
Effects of rapid chest compression technique on intracranial and cerebral perfusion pressures in acute neurocritical patients: a randomized controlled trial	30
Correction: Co-infection and ICU-acquired infection in COVID-19 ICU patients: a secondary analysis of the UNITE-COVID data set	30
Predicting early prone position ventilation responsiveness in patients with acute respiratory distress syndrome based on electrical impedance tomography: a prospective study	30
Rezafungin: an opportunity to personalize the treatment of patients with candidemia	30
Do critical illness survivors with multimorbidity need a different model of care?	30
Prognostic value of brainstem auditory evoked potentials (BAEPs) and middle latency auditory evoked potentials (MLAEPs) in unconscious patients after cardiac arrest	30
Correction: Using arterial-venous oxygen difference to guide red blood cell transfusion strategy	30