OOIR: Observatory of International Research

Papers

(The H4-Index of Current Opinion in Chemical Biology is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Fluorogenic polymethine dyes by intramolecular cyclization	152
Small-molecule modulators of protein–RNA interactions	79
Noncytotoxic catalytic enzyme functional mimics including cyanide poisoning antidotes	76
Engineered metallobiocatalysts for energy–relevant reactions	75
Peptide-based molecules for the disruption of bacterial Hsp70 chaperones	67
Recent advances in the structural analysis of adenylation domains in natural product biosynthesis	64
Imaging of proteases using activity-based probes	60
Glycosidase mechanisms: Sugar conformations and reactivity in endo- and exo-acting enzymes	60
Glycoengineering in antigen-specific immunotherapies	58
Editorial Board	54
Activity-based protein profiling in microbes and the gut microbiome	53
Accessing and exploring the unusual chemistry by radical SAM-RiPP enzymes	51
The Ramifications of synthetic biology	51
Synthetic transporters for oxoanions	51
Caged lipid probes for controlling lipid levels on subcellular scales	50
Site-specific bioconjugation and nuclear imaging	49
Recent advances in methods for quantifying the cell penetration of macromolecules	48
Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome	46
Recent advances in proximity labeling for chemical proteomics: Paving the way for in vivo applications	45
Extendable and explainable deep learning for pan-cancer radiogenomics research	44
Characteristics of genetic tags for correlative light and electron microscopy	43
Chemical inhibitors of transcription-associated kinases	42
From the forest floor to the lab: Insights into the diversity and complexity of mushroom polyketide synthases	41
Genetically encoded fluorescent sensors for metals in biology	41
Selenium vitaminology: The connection between selenium, vitamin C, vitamin E, and ergothioneine	41

Chemo- and opto-genetic tools for dissecting the role of membrane contact sites in living cells: Recent advances and limitations	40
Network biology bridges the gaps between quantitative genetics and multi-omics to map complex diseases	39
Advances in the understanding and exploitation of carbohydrate-active enzymes	38
Highlighting the roles of transition metals and speciation in chemical biology	37
Editorial Board	37
Critical considerations in N-glycoproteomics	37
Multinuclear non-heme iron dependent oxidative enzymes (MNIOs) involved in unusual peptide modifications	37
Chemistry and biology of enzymes in protein glutathionylation	37
Editorial Board	36
Super-multiplexed vibrational probes: Being colorful makes a difference	36
Natural and engineered precision antibiotics in the context of resistance	36
Towards chemoenzymatic labeling strategies for profiling protein glycosylation	36