OOIR: Observatory of International Research

Papers

(The H4-Index of Current Pharmaceutical Design is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Analysis of the Growth and Development of Children Born with ICSI of Epididymal and Testicular Spermatozoa: A Propensity Matching Study	107
Protective Effects of the Aqueous Extract of Malva sylvestris Plant against the Lethality and Histopathological Damage in Experimental Envenoming of Hemiscorpius lepturus Venom in Balb/c	91
Drug Release and Stability Study of Innovated Losartan Potassium and Rosuvastatin Calcium Fixed-dose Combination Tablet	82
Cytokines as Potential Therapeutic Targets and their Role in the Diagnosis and Prediction of Cancers	82
Computational Exploration of Flavonoids as HCV NS3/4A Protease Inhibitors: Advancing Antiviral Therapies to Mitigate Liver Cancer Risk	71
Salivary Antiviral and Antibacterial Properties in the Encounter of SARS-CoV-2	65
Traditional Uses, Phytochemistry, and Pharmacological Activities of Coleus amboinicus: A Comprehensive Review	56
Mendelian Randomization Study on Serum Metabolites and Diabetic Nephropathy Risk: Identifying Potential Biomarkers for Early Intervention	54
Immune-mediated Bowel Disease: Role of Intestinal Parasites and Gut Microbiome	53
Nanoparticles in CNS Therapeutics: Pioneering Drug Delivery Advancements	52
Is Adrenaline Always the First Choice Therapy of Anaphylaxis? An Allergist-cardiologist Interdisciplinary Point of View	51
Rosuvastatin Improves Endothelial Dysfunction in Diabetes by Normalizing Endoplasmic Reticulum Stress via Calpain-1 Inhibition	44
A Hydrogel for Nitric Oxide Sensitization Chemotherapy Mediated by Tumor Microenvironment Changes in 3D Spheroids and Breast Tumor Models	42
CRISPR-Cas9 for the Treatment of Transthyretin Cardiac Amyloidosis	41
Elucidation of the Molecular Mechanism of Compound Danshen Dripping Pills against Angina Pectoris based on Network Pharmacology and Molecular Docking	39
Topoisomerase Enzyme Inhibitors as Potential Drugs Against Cancer: What Makes Them Selective or Dual? – A Review	35
Prevalence and Death Rate of COVID-19 in Autoimmune Systemic Diseases in the First Three Pandemic Waves. Relationship with Disease Subgroups and Ongoing Therapies	35
Development of Chitosan-Coated Liposomes for Oral Delivery of Nadolol: Preparation, Characterization, and in vitro Permeability Studies	34
Non-synonymous Single Nucleotide Polymorphisms in Human ACE2 Gene May Affect the Infectivity of SARS-CoV-2 Omicron Subvariants	34
Associations Between microRNA-related Genetic Polymorphisms and Clinical Response to Methotrexate in Chinese Rheumatoid Arthritis Patients	34
Impact of Combination Therapy with Chemical Drugs and Megavoltage X-ray Exposure on Breast Cancer Stem Cells’ Viability and Proliferation of MCF-7 and MDA-MB-231 Cell Lines	33
Molecularly Imprinted Polymers (MIPs): A Multifaceted Tool in Modern Analysis	32
Computational Approaches to Designing Antiviral Drugs against COVID-19: A Comprehensive Review	30
Role of Oxidative Stress and Inflammation in Insomnia Sleep Disorder and Cardiovascular Diseases: Herbal Antioxidants and Anti-inflammatory Coupled with Insomnia Detection using Machine Learning	29
ITGA9: Potential Biomarkers and Therapeutic Targets in Different Tumors	27

Colorectal Cancer Stem Cell Biomarkers: Biological Traits and Prognostic Insights	27
Exploring 4D Printing Technology for Biomedical Applications	27
The Potential Mechanism of Liujunzi Decoction in the Treatment of Breast Cancer based on Network Pharmacology and Molecular Docking Technology	27
Phytoestrogens: A Promising Therapeutic Approach for Endometriosis Management, Insights from Preclinical and Clinical Studies	27
The Progress of Immune Cells-induced Inflammatory Response in Gout	27
Novel Approaches to the Management of Diabetes Mellitus in Patients with Coronary Artery Disease	27