OOIR: Observatory of International Research

Papers

(The TQCC of Mutation Research-Genetic Toxicology and Environmental Mutagenesis is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Cancer risk following low doses of ionising radiation – Current epidemiological evidence and implications for radiological protection	37
Mechanisms underlying the pathophysiology of type 2 diabetes: From risk factors to oxidative stress, metabolic dysfunction, and hyperglycemia	34
Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?	21
Mitomycin C induced genotoxic stress in endothelial cells is associated with differential expression of proinflammatory cytokines	21
N-acetyl-l-cysteine mediated regulation of DNA fragmentation, an apoptotic event, against methoxychlor toxicity in the granulosa cells of ovarian antral follicles	20
Crosstalk between different DNA repair pathways for DNA double strand break repairs	19
Pro-inflammatory response and genotoxicity caused by clay and graphene nanomaterials in A549 and THP-1 cells	18
Key read across framework components and biology based improvements	18
Measurement of oxidatively damaged DNA in mammalian cells using the comet assay: Reflections on validity, reliability and variability	17
EURL ECVAM Genotoxicity and Carcinogenicity Database of Substances Eliciting Negative Results in the Ames Test: Construction of the Database	16
Cadmium selenide (CdSe) quantum dots cause genotoxicity and oxidative stress in Allium cepa plants	15
Strategies in genotoxicology: Acceptance of innovative scientific methods in a regulatory context and from an industrial perspective	15
Genotoxicity of selected pyrrolizidine alkaloids in human hepatoma cell lines HepG2 and Huh6	14
Establishment and multiparametric-cytogenetic validation of 60Co-gamma-ray induced, phospho-gamma-H2AX calibration curve for rapid biodosimetry and triage management during radiological emergencies	14
Gasoline-station workers in Brazil: Benzene exposure; Genotoxic and immunotoxic effects	14
Genotoxicity and cellular uptake of nanosized and fine copper oxide particles in human bronchial epithelial cells in vitro	13
Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks	13
Differential effects of cisplatin combined with the flavonoid apigenin on HepG2, Hep3B, and Huh7 liver cancer cell lines	12
TiO2 genotoxicity: An update of the results published over the last six years	12
The 3D reconstructed skin micronucleus assay using imaging flow cytometry and deep learning: A proof-of-principle investigation	12
Influence of bariatric surgery induced weight loss on oxidative DNA damage	11
Genotoxicant exposure, activation of the aryl hydrocarbon receptor, and lipid peroxidation in cultured human alveolar type II A549 cells	10
Calibration of the comet assay using ionising radiation	10
Ionizing radiation, genotoxic stress, and mitochondrial DNA copy-number variation in Caenorhabditis elegans: droplet digital PCR analysis	10
Smoking, chromosomal aberrations, and cancer incidence in healthy subjects	9

Genotoxicity of three mycotoxin contaminants of rice: 28-day multi-endpoint assessment in rats	9
Induction of genotoxicity and mutagenic potential of heavy metals in Thai occupational workers	9
Genotoxic effects of silver nanoparticles on a tropical marine amphipod via feeding exposure	8
Alternariol monomethyl ether toxicity and genotoxicity in male Sprague-Dawley rats: 28-Day in vivo multi-endpoint assessment	8
Genomic instability in people living with HIV	8
New insight into the antigenotoxic activity of Gentiana lutea extracts – Protective effect against food borne mutagens	7
Mutagenicity of N-acyloxy-N-alkoxyamides as an indicator of DNA intercalation: The role of fluorene and fluorenone substituents as DNA intercalators	7
Mode of action assessment of the genotoxic properties of antimony and its compounds evaluated in the ToxTracker assay	7
2-Methylfuran: Toxicity and genotoxicity in male Sprague-Dawley rats	7
Mechanism of reactive oxygen species generation and oxidative DNA damage induced by acrylohydroxamic acid, a putative metabolite of acrylamide	7
Genetic damage in coal and uranium miners	7
Increased micronucleus frequencies in reticulocytes of children exposed to industrial pollution: oxidative stress and the OGG1 S326C polymorphism	7
Evaluation of genotoxic damage in buccal mucosa cytome assays in Iraqi school children exposed to air pollutants emanating from oil fields	6
Exposure of patients to low doses of X-radiation during neuro-interventional imaging and procedures: Dose estimation and analysis of γ-H2AX foci and gene expression in blood lymphocytes	6
Genotoxicity of the organophosphate pesticide malathion and its metabolite dimethylthiophosphate in human cells in vitro	6
Toxicity screening of air extracts representing different source sectors in the Greater Toronto and Hamilton areas: In vitro oxidative stress, pro-inflammatory response, and toxicogenomic analysis	6
Use of the alkaline comet assay for monitoring genotoxic effects of arsenic in human populations	6
D-10-camphorsulfonic acid: Safety evaluation	6
Cytogenetic monitoring of peripheral blood lymphocytes from medical radiation professionals occupationally exposed to low-dose ionizing radiation	6
Genotoxicity studies with an ethanolic extract of Kalanchoe pinnata leaves	6
Consumption pattern and genotoxic potential of various smokeless tobacco products in Assam, India: A public health concern	6
Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug-related metabolite, or drug-	6
Low dose radiation mechanisms: The certainty of uncertainty	6
Repurposing sodium diclofenac as a radiation countermeasure agent: A cytogenetic study in human peripheral blood lymphocytes	6
Emerging roles of DNA topoisomerases in the regulation of R-loops	5
Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence	5
Shortened telomere length in peripheral blood leukocytes of patients with lung cancer, chronic obstructive pulmonary disease in a high indoor air pollution region in China	5
Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency	5
Guidance for publishing comet assay results	5
Effects of sulforaphane on the oxidative response, apoptosis, and the transcriptional profile of human stomach mucosa cells in vitro	5
Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts	5
High homocysteine promotes telomere dysfunction and chromosomal instability in human neuroblastoma SH-SY5Y cells	5
Ionizing radiation-induced genotoxic and oxidative damage in peripheral lymphocytes and plasma of healthy donors	5
Exposure to hypomethylating 5-aza-2′-deoxycytidine (decitabine) causes rapid, severe DNA damage, telomere elongation and mitotic dysfunction in human WIL2-NS cells	5
Genomic instability evaluation by BMCyt and telomere length in Brazilian family farmers exposed to pesticides	5
In vitro genotoxicity assessment of graphene quantum dots nanoparticles: A metabolism-dependent response	5
Synephrine and caffeine combination promotes cytotoxicity, DNA damage and transcriptional modulation of apoptosis-related genes in human HepG2 cells	5
Comprehensive review of genotoxicity data for diclofenac	5
Short- and long-term reproducibility of the COMET assay for measuring DNA damage biomarkers in frozen blood samples of the EPIC-Heidelberg cohort	5
Evaluation of the genotoxic and cytotoxic effects of exposure to the herbicide 2,4-dichlorophenoxyacetic acid in Astyanax lacustris (Pisces, Characidae) and the potential for its removal from contamin	5
Women rag pickers at a dump in Ahmedabad: Genotoxicity and oxidative stress	4
Retrospective cytogenetic analysis of unstable and stable chromosome aberrations in the victims of radiation accident in Bulgaria	4
Genotoxicity assessment of root extracts of Paeonia lactiflora Pall	4
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide	4
Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay	4
Ex vivo/in vitro effects of aspirin and ibuprofen, bulk and nano forms, in peripheral lymphocytes of prostate cancer patients and healthy individuals	4
Brazilian workers occupationally exposed to different toxic agents: A systematic review on DNA damage	4
Transcription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol	4
Histone deacetylase inhibitor 2-hexyl-4-pentynoic acid enhances hydroxyurea therapeutic effect in triple-negative breast cancer cells	4
Modulation of DNA damage by XPF, XPG and ERCC1 gene polymorphisms in pesticide-exposed agricultural workers of Punjab, North-West India	4

Cytotoxicity and genotoxicity of blue LED light and protective effects of AA2G in mammalian cells and associated DNA repair deficient cell lines	4
Evaluation of the genotoxic and antigenotoxic effects of exopolysaccharide pullulan in human lymphocytes in vitro	4
Maternal overnutrition before and during pregnancy induces DNA damage in male offspring: A rabbit model	4
In vitro toxicity and internalization of gold nanoparticles (AuNPs) in human epithelial colorectal adenocarcinoma (Caco-2) cells and the human skin keratinocyte (HaCaT) cells	4
Genotoxicity test battery – An assessment of its utility in early drug development	4
Effects of isolated and combined exposures of Boana curupi (Anura: Hylidae) tadpoles to environmental doses of trichlorfon and ultraviolet radiation	4
Analysis of chromosomal aberrations and γH2A.X foci to identify radiation-sensitive ataxia-telangiectasia patients	4
Epigenetic effects of graphene oxide and its derivatives: A mini-review	4